Download or read book Magnetic Resonance of Myelin Myelination and Myelin Disorders written by Marjo S. van der Knaap and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 1255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clearly structured, each chapter describes: * clinical features and laboratory investigations * pathology * pathogenetic considerations * therapy * case presentation * MRI and spectroscopy of a specific myelin disorder Completely updated and expanded by 20 chapters to include the latest information on: - inborn errors of metabolism and neurodegenerative disorders - the role of subcellular structures - enzyme biochemistry - the pathophysiological mechanisms of posthypoxic-ischemic cerebral damage - inflammatory and infectious disorders Plus: Greater coverage of the genetic and pathophysiological mechanisms underlying white matter disorders. Finally: 250 high-quality illustrations depict rare disorders which previously were only described.
Download or read book Magnetic Resonance of Myelination and Myelin Disorders written by Marjo S. van der Knaap and published by Springer Science & Business Media. This book was released on 2005-08-15 with total page 1097 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our thanks go to our colleagues at the VU Univer- Preface to the Third Edition sity Medical Center and to those in other hospitals Reading through the prefaces of the two previous edi- who referred their patients to us. We are indebted to tions,we can say that much of what was said there still all colleagues who allowed us to use their MR images, holds. At the same time,however,much has changed. published or unpublished,making it possible for us to There has been immense progress in the technical present illustrations of nearly all known white matter possibilities of magnetic resonance and in the know- disorders. Two colleagues were particularly helpful ledge of genetic defects, biochemical abnormalities, and provided us with essential and unpublished f- and cellular processes underlying myelin disorders. ures: our friends Susan Blaser,from the Hospital for This immense progress has prompted us to embark Sick Children in Toronto,and Zoltán Patay,from the upon the enormous task of rewriting the previous King Faisal Hospital in Riyadh. edition and adding 40 chapters. In doing so we have Many people at the VU University Medical Center tried to cover most white matter disorders,hereditary have been of great technical help to us in producing and acquired,and to present a collection of images to high quality images and in providing secretarial illustrate the field to the fullest possible extent. This assistance. The contributions of these people are edition will therefore be more complete than the pre- mentioned separately in the acknowledgements.
Download or read book Magnetic Resonance of Myelin Myelination and Myelin Disorders written by Jacob Valk and published by Springer Science & Business Media. This book was released on 1989 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Magnetic Resonance of Myelin Myelination and Myelin Disorders written by Marjo S. van der Knaap and published by . This book was released on 1995 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second, completely rewritten edition of the widely acclaimed book on MR of myelin, myelination and myelin disorders (1989). In the last five years many new data became available with regard to genetics, molecular biology, the role of cellular substructures on one side and on the other side regarding the growing experience with MR patterns of less common myelin disorders. Not only, therefore, the text has been updated, but many new chapters have been added on disorders of which previously the white matter involvement was less clear. The acquired myelin disorders were reorganized and their backgrounds were more extensively elucidated, to place the MR examinations in the clinical context where they belong.
Download or read book Myelination and Myelin Disorders written by Marjo S. van der Knaap and published by . This book was released on 1991 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Myelination and Demyelination written by Seung U. Kim and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: In June 1987, neurobiologists, immunologists, molecular biologists, virologists and neurologists from several countries met in Vancouver to discuss recent advances of relevance to multiple sclerosis. The symposium was a part of the 22nd Canadian Congress of Neurological Sciences meeting and was sponsored by funds from the Multiple Sclerosis Society of Canada and the Medical Research Council of Canada. The presentations covered five major topics: basic neurobiology, molecular biology, the role of viruses in demyelination, immune function and dysfunction in multiple sclerosis, and clinical magnetic resonance imaging studies. It was heartening to note that scientists from several different disciplines were working towards a common end-point: the understanding and treatment of multiple sclerosis. In this book, speakers at the symposium have each presented a chapter of their findings and discussions. In addition, some non-participants at the symposium have been invited to submit chapters in order to give this volume a more complete scope. It is hoped that the reader will find this book a useful reference for several subjects of interest to multiple sclerosis. In closing, I would like to thank the following for their help and support: the Multiple Sclerosis Society of Canada and the Medical Research Council of Canada for their financial support; the contributors of this book for their manuscripts; Dr. A. Eisen, Mrs. K. Eisen, Mrs. P. Bodnarchuk and Mrs. M. Kim for their efforts in planning and organizing the symposium; and Ms. Catherine Schikowski for her secretarial assistance. Seung U. Kim, M.D. Ph.D.
Download or read book Visual System in Myelin Disorders written by A. Neetens and published by Springer Science & Business Media. This book was released on 1984-01-31 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Myelination and Demyelination written by Jarma Palo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: A satellite symposium entitled "Myelination and Demyelination: Recent Chemical Advances" was held in Helsinki from August 29 to 31, 1977, after the Sixth International Meeting of the International Society for Neurochemistry (ISN) in Copenhagen. Myelin is a nervous tissue structure that is most suitable as a subject of biochemical investigation. It is easy to isolate in a highly purified form, is rather stable even after death, and is af fected by a variety of neurological and other diseases. Its lesions are particularly important in the study of multiple sclerosis, a disease which is relatively prevalent in Finland and has therefore been of interest to a great many Finnish scientists. The first half of this book is concerned with the biochemical composition and molecular organization of myelin, the second half with the experimental and clinical aspects of demyelination. The comments given after each of the presentations at the symposium were not recorded as such, but each author was requested to modify his or her paper accordingly. The editing and publication of this book would not have been possible without the excellent efforts and co-operation of my wife, Mrs. L.-M. Palo, acting as general secretary and later as editorial secretary of the symposium. As Organizing Committee Chairman, I would also like to thank the members of the Committee: Dr. M. Haltia, Dr. E. Kivalo, Dr. T. Kosunen, Dr. M. Panelius, and especially Dr.
Download or read book Myelin written by Kazunori Sango and published by Springer Nature. This book was released on 2019-11-23 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest exciting advances in understanding of the structure and function of myelin in the central and peripheral nervous systems under normal and pathological conditions. Readers will find state of the art information from the perspectives of both basic neuroscience and clinical neurology and neuropathology. Detailed attention is paid to the findings and implications of recent research on the myelin-forming glial cells such as oligodendrocytes and Schwann cells. The discussion of myelin pathology encompasses a wide range of diseases and conditions, including, for example, multiple sclerosis, Pelizaeus-Merzbacher disease, traumatic brain and spinal cord injuries, brain tumors of glial cell origin, Charcot-Marie-Tooth disease, immune-mediated neuropathy, and diabetic neuropathy. The authors comprise researchers at the cutting edge of biotechnology and experts in the diseases discussed. The clearly written text is supported by numerous high-quality light and electron microscopy, CT, and MR images.
Download or read book Myelin Biology and Disorders written by Robert A. Lazzarini and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Myelin written by Pierre Morell and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: The division of the mature mammalian brain and spinal cord into regions of "white" matter and "gray" matter is observable upon the most cursory inspection. Microscopic examination indicates that the "white" matter regions are characterized by a multilamellar sheath (myelin) which sur rounds the axons. A morphologically similar myelin imparts the white color to tracts of the peripheral nervous system, although, as is empha sized throughout the book, there are very significant morphological and chemical differences between central and peripheral myelin. The rapid postnatal accumulation of myelin is temporally associated with increasing functional capacity and presumably indicates some important role related to neuronal activity. The ability of myelinated axons to conduct electrical impulses much more rapidly and with much lower use of energy, relative to unmyelinated axons, is now generally accepted. As is evident from the above capsule description, a considerable body of information concerning myelin is available. However, as in other areas of research the unknown expands before us more rapidly than we are able to add to our core of knowledge. This is a corollary of the axiom that a good experiment raises more questions than it answers. Among the areas currendy under investigation in many laboratories are the following: interaction of myelin-forming cells with neurons, assembly and metabo lism of myelin, molecular architecture of myelin, and the details of the functional role of myelin.
Download or read book Magnetic Resonance of Myelination and Myelin Disorders 2005 written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Myelin Repair and Neuroprotection in Multiple Sclerosis written by Ian D. Duncan and published by Springer Science & Business Media. This book was released on 2012-08-31 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myelin Repair and Neuroprotection in Multiple Sclerosis presents an up-date on the translational potential of promoting remyelination in multiple sclerosis (MS). A number of research frontiers still exist in this challenging disease. The cause remains elusive, preventing breakthroughs in its prevention. The move towards oral immunomodulatory therapies has been a major advance, as has the finding of new genes linked to susceptibility that may open the door to new therapeutic approaches. However, a frontier that has been making significant strides in recent years has been that surrounding the neurobiology of myelin regeneration and axon protection: such have been the advances that clinical translation is on the cusp of being achieved. Two broad approaches to therapeutic enhancement of remyelination are envisaged: promoting endogenous remyelination by targeting cells present in the CNS, or, replacing lost myelinating cells from exogenous sources. Current research on oligodendrocyte biology, the pathology of MS, imaging of lesions and the biology of remyelination are paving the way toward opening this new translational frontier. Professor Duncan and Professor Franklin have assembled a broad group of experts in the fields of glial cell biology, neuropathology, radiology and clinical neurology to provide the background toward taking remyelination from experimented models into MS patients.
Download or read book Netter s Atlas of Neuroscience written by David L. Felten and published by Elsevier Health Sciences. This book was released on 2015-11-30 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal for students of neuroscience and neuroanatomy, the new edition of Netter's Atlas of Neuroscience combines the didactic well-loved illustrations of Dr. Frank Netter with succinct text and clinical points, providing a highly visual, clinically oriented guide to the most important topics in this subject. The logically organized content presents neuroscience from three perspectives: an overview of the nervous system, regional neuroscience, and systemic neuroscience, enabling you to review complex neural structures and systems from different contexts. You may also be interested in: A companion set of flash cards, Netter's Neuroscience Flash Cards, 3rd Edition, to which the textbook is cross-referenced. Coverage of both regional and systemic neurosciences allows you to learn structure and function in different and important contexts. Combines the precision and beauty of Netter and Netter-style illustrations to highlight key neuroanatomical concepts and clinical correlations. Reflects the current understanding of the neural components and supportive tissue, regions, and systems of the brain, spinal cord, and periphery. Uniquely informative drawings provide a quick and memorable overview of anatomy, function, and clinical relevance. Succinct and useful format utilizes tables and short text to offer easily accessible "at-a-glance" information. Provides an overview of the basic features of the spinal cord, brain, and peripheral nervous system, the vasculature, meninges and cerebrospinal fluid, and basic development. Integrates the peripheral and central aspects of the nervous system. Bridges neuroanatomy and neurology through the use of correlative radiographs. Highlights cross-sectional brain stem anatomy and side-by-side comparisons of horizontal sections, CTs and MRIs. Features video of radiograph sequences and 3D reconstructions to enhance your understanding of the nervous system. Student Consult eBook version included with purchase. This enhanced eBook experience includes access -- on a variety of devices -- to the complete text, 14 videos, and images from the book. Expanded coverage of cellular and molecular neuroscience provides essential guidance on signaling, transcription factors, stem cells, evoked potentials, neuronal and glial function, and a number of molecular breakthroughs for a better understanding of normal and pathologic conditions of the nervous system. Micrographs, radiologic imaging, and stained cross sections supplement illustrations for a comprehensive visual understanding. Increased clinical points -- from sleep disorders and inflammation in the CNS to the biology of seizures and the mechanisms of Alzheimer's -- offer concise insights that bridge basic neuroscience and clinical application.
Download or read book Myelin written by Russell E. Martenson and published by Taylor & Francis. This book was released on 2023-02-06 with total page 1006 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myelin: Biology and Chemistry provides in-depth reviews and discussions regarding recent findings in the biology and chemistry of myelin. Topics are interdisciplinary and carry readers from the cellular level to that of the gene. Research in demyelinating diseases (naturally occurring and experimentally produced) is described and emphasizes autoimmune and virally induced mechanisms. Advances in molecular biology, such as those that provide details of the structures of the major myelin proteins, demonstrate the control of their synthesis, and explore the mutations within their genes that disrupt the process of myelination, are discussed in depth. Myelin: Biology and Chemistry will be an important addition to the libraries of molecular biologists, biochemists, cell biologists, physical chemists, immunologists, virologists, and pathologists involved in the study of myelin.
Download or read book A Multidisciplinary Approach to Myelin Diseases II written by S. Salvati and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: The diseases that fall under the generalized group of demyelinating diseases -Multiple Sclerosis, Leukodystrophyes, Encephalomyelitis-are the focus of worldwide concern. This volume contains papers presented by leading scientists who attended the NATO Advanced Research Workshop held at the Istituto Superiore di SanitA, Rome, March 1-4, 1993. This book is an update of the previous one published in 1987 of the research discussed at a similar meeting held in 1986. It was decided to hold this 2nd meeting since there has been great progress in the advances in understanding the myelinogenesis process in the last five years. The workshop gathered together scientists from many fields such as cellular and molecular biology, immunology, pathology, virology and of course clinical neurology. Stimulating ideas were exchanged in the hope that more knowledge of demyelinating diseases can lead to new theraupetic approaches. Although the workshop was on the whole similar to the previous one, this time there was more emphasis on experimental models and clinical aspects. In the former the use of animal and cellular models as tools for understanding the pathological mechanisms linked to human disease were discussed; in the latter the clinicians described the filtering down of basic research to clinical treatment The publication of this interdisciplinary exchange is to make known the results of the most recent research among the investigators from allover the world involved in these studies.
Download or read book Disorders of Myelin in the Central and Peripheral Nervous Systems written by Fernando Dangond and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: * Comprehensive reference on all disorders of myelin * Includes both basic science and clinical material * Contains the most recent results of clinical trials in multiple sclerosis Comprehensive reference on all disorders of myelin Includes both basic science and clinical material Contains the most recent results of clinical trials in multiple sclerosis
