Download or read book Mycobacterium Tuberculosis Pathogenesis Infection Prevention and Treatment written by Riccardo Miggiano and published by Mdpi AG. This book was released on 2020-10 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled "Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment" that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies.
Download or read book Mycobacterium Tuberculosis Pathogenesis Infection Prevention and Treatment written by Davide Maria Ferraris and published by . This book was released on 2020 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled “Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment” that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies.
Download or read book Tuberculosis in Adults and Children written by Dorothee Heemskerk and published by Springer. This book was released on 2015-07-17 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.
Download or read book Tuberculosis written by Barry R. Bloom and published by . This book was released on 1994 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors discuss fundamental questions about the biology, genetics, mechanisms of pathogenicity, mechanisms of resistance, and drug development strategies that are likely to provide important new knowledge about TB and new interventions to prevent and treat this disease.
Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Download or read book Tuberculosis Pathogenesis and Control written by Megan Durham and published by Foster Academics. This book was released on 2019-06-24 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tuberculosis (TB) is an infectious disease primarily affecting the lungs. It is caused by a species of pathogenic bacteria called mycobacterium tuberculosis. TB infection converts into disease when the immune system defenses are overcome by bacilli that begin to multiply. Tuberculosis can also reoccur after treatment especially in patients with HIV. A short course treatment of TB involves the use of antibiotics such as isoniazid, rifampicin, ethambutol, etc. These are known as first-line drugs. A series of second-line drugs may also be used in case the first-line drugs prove to be inefficient to treat the disease. This book discusses the fundaments as well as modern approaches of tuberculosis pathogenesis, control and treatment. The topics included herein are of utmost significance and bound to provide incredible insights to readers.
Download or read book Tuberculosis written by M. Monir Madkour and published by Springer Science & Business Media. This book was released on 2003-11-18 with total page 974 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive textbook on tuberculosis that covers all aspects of the disease: epidemiology, microbiology, diagnosis, treatment, control and prevention. The main part of the book comprises very detailed and richly illustrated clinical chapters. The copious images are the advantage of this book. Chapters on new methods and treatments and on animal tuberculosis are included. The material is based on a wealth of experience in tuberculosis as seen in endemic countries such as Saudi Arabia that enjoy free access to advanced investigative and therapeutic facilities. This coexistence of endemicity of the disease and state-of-the-art facilities is rare in poor and developing countries or in rich and developed nations. This multidisciplinary volume is ideal for all clinicians, laboratory and research workers, epidemiologists, university teachers and students, health care planners and international organizations involved in world health and infectious disease.
Download or read book Mycobacterium Tuberculosis Molecular Infection Biology Pathogenesis Diagnostics and New Interventions written by Seyed Ehtesham Hasnain and published by Springer Nature. This book was released on 2019-11-30 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease. Despite being completely curable, tuberculosis is still one of the leading global causes of death. M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. Presenting a wealth of information on the molecular infection biology of M. tuberculosis, as well as nontuberculous mycobacteria (NTM), the book provides an overview of the functional role of the PE/PPE group of proteins, which is exclusive to the genus Mycobacteria, of host-pathogen interactions, and virulence. It also explores the pathogenesis of the infection, pathology, epidemiology, and diagnosis of NTM. Finally it discusses current and novel approaches in vaccine development against tuberculosis, including the role of nanotechnology. With state-of-the-art contributions from experts in the respective domains, this book is an informative resource for practitioners as well as medical postgraduate students and researchers.
Download or read book Tuberculosis Pathogenesis Diagnosis and Treatment written by June Middleton and published by American Medical Publishers. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tuberculosis (TB) is a contagious disease that mainly causes damage to the lungs. This disease is caused by the Mycobacterium tuberculosis (Mtb) bacteria. It can be transmitted from an infected person to a healthy person, through tiny droplets released while sneezing and coughing. Some common symptoms of TB include coughing for more than three weeks, chest pain, or pain while coughing and breathing, fatigue, fever, and loss of appetite. Several conditions like diabetes, severe kidney disease, malnutrition, and HIV makes a person more prone to TB bacteria by reducing the capacity of immune system to work efficiently. Tuberculosis can cause death if left untreated. Furthermore, it is a leading cause of complications like spinal pain, swelling in the membranes covering the brain, heart disorders, and liver or kidney problems. Its diagnosis starts with a physical examination of lymph nodes for swelling. Other diagnostic methods include blood tests, imaging tests and sputum tests. DOT (directly observed therapy) is a predominant treatment of TB. This book includes some of the vital pieces of work being conducted across the world, on various topics related to tuberculosis. It will provide comprehensive knowledge to the readers on the pathogenesis, diagnosis and treatment of this disease.
Download or read book WHO operational handbook on tuberculosis Module 1 written by World Health Organization and published by World Health Organization. This book was released on 2023-08-31 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infection prevention and control activities are amongst the key components envisaged by the End TB Strategy to curb the tuberculosis (TB) burden worldwide. This handbook provides practical advice on how to implement the WHO recommendations on TB infection prevention and control within the clinical and programmatic management of TB, using a public health approach. The guidance emphasizes the importance of building integrated, well-coordinated, multisectoral actions across all levels of health care and other settings where there is a high risk of M. tuberculosis transmission. It shares best practices and experiences and provides checklists and job aids to support the implementation and monitoring of actions to cut transmissions, and promotes an implementation hierarchy of interventions across all settings as an integrated package. The target audience for the handbook includes policy-makers at national and subnational level; programme managers for TB, HIV and noncommunicable disease programmes; managers and clinicians at inpatient and outpatient health care facilities; managers at various congregate settings; occupational health officials; engineers; medical practitioners; frontline health care workers; and other key stakeholders in the public and private sectors.
Download or read book Tuberculosis A Clinical Practice Guide written by Rafael Laniado-Laborín and published by Bentham Science Publishers. This book was released on 2020-12-01 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tuberculosis is an infection of the lungs caused by Mycobacterium tuberculosis and related species. It is prevalent in tropical regions and continues to occur in more than 10 million new individuals annually and despite many advances in medicine, still results in 1.3 million deaths annually. This clinical practice handbook presents information on all topics related to the disease, including its epidemiology, microbiology, clinical features, diagnostic procedures, treatments, BCG vaccination and infection control in health facilities. Special topics such as the treatment of tuberculosis is pediatric patients, surgery, multi-drug resistance and adverse reactions to tuberculosis drugs are also covered. Information is presented in 16 simple easy-to read chapters with key figures, tables and references that help to explain relevant topics. Tuberculosis: A Clinical Practice Guide is an ideal reference manual for medical students and healthcare personnel seeking information about tuberculosis.
Download or read book WHO consolidated guidelines on tuberculosis written by World Health Organization and published by World Health Organization. This book was released on 2022-08-12 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the targets of the Sustainable Development Goals (SDGs) for the period 2015-2030 is to end the global TB epidemic. In line with this target, the WHO End TB Strategy, approved by the World Health Assembly in 2014, calls for a 90% reduction in TB deaths and an 80% decrease in the TB incidence rate by 2030. The strategy emphasizes the need for prevention across all approaches, including infection prevention and control (IPC) in health care services and other settings where the risk of Mycobacterium tuberculosis transmission is high. IPC practices are vital to reduce the risk of M. tuberculosis transmission, by reducing the concentration of infectious droplet nuclei in the air and the exposure of susceptible individuals to such aerosols. Initial WHO recommendations on TB IPC focused primarily on decreasing the risk of transmission in health care facilities in resource-limited settings.17,18 These initial recommendations were then expanded in 2009 to provide further guidance on the use of specific measures for health care facilities, congregate settings and households. After the 2009 guidelines had been in effect for almost 10 years, the need for an update was anticipated, to provide a revised evidence assessment, reinforcing earlier recommendations and linking to core components of effective IPC programmes overall. The present updated guidelines also stress the importance of implementing IPC measures in a systematic and objective way that prioritizes consideration of the hierarchy of IPC controls.
Download or read book Molecular Epidemiology Study of Mycobacterium Tuberculosis Complex written by Yogendra Shah and published by BoD – Books on Demand. This book was released on 2021-09-15 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tuberculosis (TB), which is caused by the infectious agent Mycobacterium tuberculosis (MTB), is a major global public health problem that infects one third of the world’s population. This book provides an overview of the molecular epidemiology pattern, transmission dynamics, host response, evolution, and pathogenesis mechanisms of TB. Chapters explore such topics as mechanisms associated with increasing trends of drug-resistant TB, the development of anti-mycobacterial drugs, genotyping tools, diagnosis and treatment of latent tuberculosis infection, and more.
Download or read book Case Studies in Infectious Disease Mycobacterium Tuberculosis written by Peter Lydyard and published by Garland Science. This book was released on 2009-12 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: Case Studies in Infectious Disease: Mycobacterium tuberculosis presents the natural history of this infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis, and treatment. A set of core questions explores the nature, causation, host response, manifestations, and management of this infectious process. This case also includes summary bullet points, questions and answers, and references.
Download or read book Target product profiles for tuberculosis preventive treatment written by World Health Organization and published by World Health Organization. This book was released on 2020-08-21 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tuberculosis and Non Tuberculous Mycobacteria Infections Control Diagnosis and Treatment written by Onya Opota and published by Frontiers Media SA. This book was released on 2021-12-31 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tuberculosis written by Mario C. Raviglione and published by CRC Press. This book was released on 2016-04-19 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every second a new person is exposed to tuberculosis (TB). Each untreated TB-infected person will infect 10-15 people every year. Following the success of its predecessor, this new edition of Tuberculosis: The Essentials scrutinizes the new discoveries and observations of the key aspects of the disease. Recognized world experts provide a concise, state-of-the-art review of the 15 essential elements of TBsupply an international, current view of the epidemiology, pathophysiology, diagnosis, and treatment methodsdiscuss the emerging threat of XDR-TB and the HIV/AIDS factorassess advances in TB research such as new drugs and vaccinesreflect on the progress of the "Stop TB" strategy.
