Download or read book Making Medicines Affordable written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-03-01 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thanks to remarkable advances in modern health care attributable to science, engineering, and medicine, it is now possible to cure or manage illnesses that were long deemed untreatable. At the same time, however, the United States is facing the vexing challenge of a seemingly uncontrolled rise in the cost of health care. Total medical expenditures are rapidly approaching 20 percent of the gross domestic product and are crowding out other priorities of national importance. The use of increasingly expensive prescription drugs is a significant part of this problem, making the cost of biopharmaceuticals a serious national concern with broad political implications. Especially with the highly visible and very large price increases for prescription drugs that have occurred in recent years, finding a way to make prescription medicinesâ€"and health care at largeâ€"more affordable for everyone has become a socioeconomic imperative. Affordability is a complex function of factors, including not just the prices of the drugs themselves, but also the details of an individual's insurance coverage and the number of medical conditions that an individual or family confronts. Therefore, any solution to the affordability issue will require considering all of these factors together. The current high and increasing costs of prescription drugsâ€"coupled with the broader trends in overall health care costsâ€"is unsustainable to society as a whole. Making Medicines Affordable examines patient access to affordable and effective therapies, with emphasis on drug pricing, inflation in the cost of drugs, and insurance design. This report explores structural and policy factors influencing drug pricing, drug access programs, the emerging role of comparative effectiveness assessments in payment policies, changing finances of medical practice with regard to drug costs and reimbursement, and measures to prevent drug shortages and foster continued innovation in drug development. It makes recommendations for policy actions that could address drug price trends, improve patient access to affordable and effective treatments, and encourage innovations that address significant needs in health care.

Download or read book The Prairie Homestead Cookbook written by Jill Winger and published by Flatiron Books. This book was released on 2019-04-02 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jill Winger, creator of the award-winning blog The Prairie Homestead, introduces her debut The Prairie Homestead Cookbook, including 100+ delicious, wholesome recipes made with fresh ingredients to bring the flavors and spirit of homestead cooking to any kitchen table. With a foreword by bestselling author Joel Salatin The Pioneer Woman Cooks meets 100 Days of Real Food, on the Wyoming prairie. While Jill produces much of her own food on her Wyoming ranch, you don’t have to grow all—or even any—of your own food to cook and eat like a homesteader. Jill teaches people how to make delicious traditional American comfort food recipes with whole ingredients and shows that you don’t have to use obscure items to enjoy this lifestyle. And as a busy mother of three, Jill knows how to make recipes easy and delicious for all ages. "Jill takes you on an insightful and delicious journey of becoming a homesteader. This book is packed with so much easy to follow, practical, hands-on information about steps you can take towards integrating homesteading into your life. It is packed full of exciting and mouth-watering recipes and heartwarming stories of her unique adventure into homesteading. These recipes are ones I know I will be using regularly in my kitchen." - Eve Kilcher These 109 recipes include her family’s favorites, with maple-glazed pork chops, butternut Alfredo pasta, and browned butter skillet corn. Jill also shares 17 bonus recipes for homemade sauces, salt rubs, sour cream, and the like—staples that many people are surprised to learn you can make yourself. Beyond these recipes, The Prairie Homestead Cookbook shares the tools and tips Jill has learned from life on the homestead, like how to churn your own butter, feed a family on a budget, and experience all the fulfilling satisfaction of a DIY lifestyle.

Download or read book Acute Pulmonary Embolism written by A. Geibel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.

Download or read book Outdoor School written by Diane Borsato and published by Douglas & McIntyre. This book was released on 2021-05 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Outdoor School features recent works of contemporary environmental art and writing by more than twenty-five Canadian and Indigenous artists who propose radical new ways of thinking about and being outdoors together.

Download or read book The ESC Textbook of Cardiovascular Medicine written by A. John Camm and published by . This book was released on 2019 with total page 3198 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Poverty and Shared Prosperity 2016 written by World Bank Group and published by World Bank Publications. This book was released on 2016-10-12 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poverty and Shared Prosperity 2016 is the first of an annual flagship report that will inform a global audience comprising development practitioners, policy makers, researchers, advocates, and citizens in general with the latest and most accurate estimates on trends in global poverty and shared prosperity. This edition will also document trends in inequality and identify recent country experiences that have been successful in reducing inequalities, provide key lessons from those experiences, and synthesize the rigorous evidence on public policies that can shift inequality in a way that bolsters poverty reduction and shared prosperity in a sustainable manner. Specifically, the report will address the following questions: • What is the latest evidence on the levels and evolution of extreme poverty and shared prosperity? • Which countries and regions have been more successful in terms of progress toward the twin goals and which are lagging behind? • What does the global context of lower economic growth mean for achieving the twin goals? • How can inequality reduction contribute to achieving the twin goals? • What does the evidence show concerning global and between- and within-country inequality trends? • Which interventions and countries have used the most innovative approaches to achieving the twin goals through reductions in inequality? The report will make four main contributions. First, it will present the most recent numbers on poverty, shared prosperity, and inequality. Second, it will stress the importance of inequality reduction in ending poverty and boosting shared prosperity by 2030 in a context of weaker growth. Third, it will highlight the diversity of within-country inequality reduction experiences and will synthesize experiences of successful countries and policies, addressing the roots of inequality without compromising economic growth. In doing so, the report will shatter some myths and sharpen our knowledge of what works in reducing inequalities. Finally, it will also advocate for the need to expand and improve data collection—for example, data availability, comparability, and quality—and rigorous evidence on inequality impacts in order to deliver high-quality poverty and shared prosperity monitoring.

Download or read book The Deep End Diary of a Wimpy Kid 15 written by Jeff Kinney and published by Penguin Group Australia. This book was released on 2020-10-27 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: In The Deep End, book 15 of the Diary of a Wimpy Kid series from #1 international bestselling author Jeff Kinney, Greg Heffley and his family hit the road for a cross-country camping trip, ready for the adventure of a lifetime. But things take an unexpected turn, and they find themselves stranded at an RV park that’s not exactly a summertime paradise. When the skies open up and the water starts to rise, the Heffleys wonder if they can save their vacation – or if they’re already in too deep. And don’t miss an all-new fantasy from Greg’s best friend in Rowley Jefferson’s Awesome Friendly Adventure, the follow-up to the instant #1 bestseller Diary of an Awesome Friendly Kid: Rowley Jefferson’s Journal.

Download or read book Diagnosis and Treatment of Aortic Diseases written by C.A. Nienaber and published by Springer Science & Business Media. This book was released on 1999-03-31 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes recent surgical techniques developed to improve prognosis in aortic diseases, and discusses recent interventional strategies such as endovascular stent-graft placement and non-surgical reconstruction of the aorta. Chapters deal with aortic dissection, aortic aneurysm, surgical treatment of aortic aneurysms and dissections, inherited disorders of the aorta, aortic trauma, aortitis, and etiology and pathology of aortic malformations. Each chapter is organized in a similar fashion, with information on demographic aspects, pathology, clinical presentation, and diagnostic and therapeutic approaches. Annotation copyrighted by Book News, Inc., Portland, OR

Download or read book CURRENT Essentials of Medicine Fourth Edition written by Lawrence M. Tierney and published by McGraw Hill Professional. This book was released on 2010-11-12 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: The perfect quick reference on the wards and in the clinic! The famous "one disease per page" design! CURRENT Essentials of Medicine is a practical, point-of-care pocket handbook that offers "nutshell" information on the diagnosis and treatment of more than 500 medical disorders seen in both primary care and hospital settings. Perfect as a quick reference on the wards or in a busy clinic, this is THE ONLY pocket guide to offer disease essentials in a one-disease-per-page bulleted format. Practical pearls, for which the authors are well known, are offered for almost all conditions. Features To-the-point information on the diagnosis and treatment of more than 500 of the most common diseases seen in clinical practice Convenient one-disease-per page presentation Bulleted data for each disease covering Essentials of Diagnosis, Differential Diagnosis, Treatment, Pearl, and Reference Encompasses both ambulatory and inpatient medicine Includes internal medicine, plus specialties such as obstetrics/gynecology, surgery, and pediatrics Updated clinical manifestations, diagnostic tests, and treatment considerations throughout

Download or read book The Elements of Preaching written by Warren W. Wiersbe and published by Tyndale House Publishers, Inc.. This book was released on 1986 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here are basic preaching principles as well as the main preaching prohibitions that can help you sharpen and focus your skills in the pulpit.

Download or read book Extreme Wine written by Mike Veseth and published by Rowman & Littlefield Publishers. This book was released on 2013-07-17 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Extreme Wine, wine economist and best-selling author Mike Veseth circles the globe searching for the best, worst, cheapest, most expensive, and most over-priced wines. Mike seeks out the most outrageous wine people and places and probes the biggest wine booms and busts. Along the way he applauds celebrity wines, tries to find wine at the movies, and discovers wines that are so scarce that they are almost invisible. Why go to such extremes? Because, Mike argues, the world of wine is growing and changing, and if you want to find out what’s really happening you can’t be afraid to step over the edge. Written with verve and appreciation for all things wine, Extreme Wine will surprise and delight readers.

Download or read book Marco Polo Didn t Go There written by Rolf Potts and published by Travelers' Tales. This book was released on 2009-04-01 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marco Polo Didn’t Go There is a collection of rollicking travel tales from a young writer USA Today has called “Jack Kerouac for the Internet Age.” For the past ten years, Rolf Potts has taken his keen postmodern travel sensibility into the far fringes of five continents for such prestigious publications as National Geographic Traveler, Salon.com, and The New York Times Magazine. This book documents his boldest, funniest, and most revealing journeys—from getting stranded without water in the Libyan desert, to crashing the set of a Leonardo DiCaprio movie in Thailand, to learning the secrets of Tantric sex in a dubious Indian ashram. Marco Polo Didn’t Go There is more than just an entertaining journey into fascinating corners of the world. The book is a unique window into travel writing, with each chapter containing a “commentary track”—endnotes that reveal the ragged edges behind the experience and creation of each tale. Offbeat and insightful, this book is an engrossing read for students of travel writing as well as armchair wanderers.

Download or read book Wine Wars II written by Mike Veseth and published by Rowman & Littlefield. This book was released on 2022-07-01 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here’s the inside scoop on the wine world. Globalization has pushed back the borders of the wine world, creating a complex, interconnected market where Old World and New World wines and producers compete head to head. Writing with wit and verve, Mike Veseth (a.k.a. the Wine Economist) tells the compelling story of the war between the market forces that are redrawing the world wine map and the terroirists who resist them. This is the battle for the future of wine—and for its soul. The fight isn't just over bottles bought and sold, however; power and taste are also at stake. Who will call the shots in the wine market of the future? Who will set the price? Whose palate will prevail? Veseth masterfully brings all of these questions together in the only book on the wine business written for all lovers of wine. Wine Wars II begins by exploring wine globalization, where readers follow “Missionaries, Migrants, and Market Reforms” to faraway New Zealand and learn how to unlock the secrets of their local retail “Wine Wall” by mastering the “DaVino Code.” Globalization brings a world of wine to our doorsteps. Commodification helps us make sense of the resulting embarrassment of riches, but at a cost. Readers must decide if they are Martians or Wagnerians, consider why “They Always Buy the Ten Cent Wine,” and then probe the puzzle of “Outlaws, Prisoners, and the Great Escape.” Who stands in the way of the global wine market's assault on wine's very soul? The“Revenge of the Terroirists!” Resistance is not futile, because 'We Are All Terroirists Now,” but that doesn't mean the future of wine is secure. A final section explores “Wine's Triple Crisis,” environmental crisis plus economic crisis, plus identity crisis. Taken together these crises pose the most serious threat to wine as we know and love it. Each section of Wine Wars II ends with a suggested wine tasting that invites readers to experience the book's ideas and arguments with all their senses by sampling a few carefully chosen wines. Can the soul of wine survive – and thrive – in this unfriendly environment? You'll have to read Wine Wars II to find out!

Download or read book Been Down So Long It Looks Like Up to Me written by Richard Farina and published by Penguin. This book was released on 1996-05-01 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: A witty, psychedelic, and telling novel of the 1960s Richard Fariña evokes the Sixties as precisely, wittily, and poignantly as F. Scott Fitzgerald captured the Jazz Age. The hero, Gnossus Pappadopoulis, weaves his way through the psychedelic landscape, encountering-among other things-mescaline, women, art, gluttony, falsehood, science, prayer, and, occasionally, truth. For more than seventy years, Penguin has been the leading publisher of classic literature in the English-speaking world. With more than 1,700 titles, Penguin Classics represents a global bookshelf of the best works throughout history and across genres and disciplines. Readers trust the series to provide authoritative texts enhanced by introductions and notes by distinguished scholars and contemporary authors, as well as up-to-date translations by award-winning translators. From the Trade Paperback edition.

Download or read book Neurogenic bladder and bowel dysfunction written by Peter Wide and published by Linköping University Electronic Press. This book was released on 2020-09-11 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal dysraphism (SD) is a congenital malformation that to a varying extent, often severely, affects the life of the child and the family. Most individuals with SD suffer from neurogenic bladder and bowel dysfunction—with the risk of urinary tract infections, renal deterioration, urinary and fecal incontinence—that affects social participation and quality of life negatively. In newborns with SD, early detection of neurogenic bladder dysfunction and determination of post-void residual urine are required to determine the need of clean intermittent catheterization (CIC) and follow-up. The non-invasive method of four-hour voiding observation with provocation test (VOP) was used to evaluate bladder function in 50 newborn children with SD. Voiding patterns for the children were described and compared with those of 50 healthy newborns evaluated with VOP in an earlier study. Comparison revealed significant differences among several variables. In particular, leakage at provocation test and not voiding with a stream were common in newborns with SD but did not occur in healthy newborns. VOP is a non-invasive standardized method to determine residual urine in newborns with SD. It also adds information on voiding pattern, frequency, voiding with a stream and leakage at provocation. Findings in neonatal VOP of the same cohort of newborns with SD were then related to radiology, presence of urinary tract infections during the first year, and urodynamic findings and use of CIC at the age of one year. It was found that, in children with SD, not voiding with a stream may have a predictive value for the need of CIC at the age of one year, followed probably by lifelong CIC. Despite this, the presence of an open SD per se has stronger predictive value, and each child needs to be evaluated individually while considering a number of factors. The main value of VOP may be as a structured non-invasive screening method to uncover neurogenic bladder-sphincter dysfunction in the newborn. Studies with a larger number of subjects than the present are needed to evaluate the potential of VOP in newborns with closed spinal dysraphism in whom the neurological consequences vary. A retrospective analysis detected renal damage on DMSA scintigraphy in 5 of 41 children with SD who were followed according to a proactive national program with minimal use of surgery. Median follow-up time was 10 years. High baseline pressure was confirmed as a risk factor for renal damage. Compliance with treatment and follow-up is likely to be an important factor for renal health. Therefore, efforts to support children and their families are crucial. A questionnaire-based study of 107 children with SD (age 6–16y) in Sweden and Norway examined aspects of treatment for neurogenic bowel dysfunction focusing on incontinence, independence, general satisfaction and quality of life. It was found that transanal irrigation (TAI) and antegrade colonic enemas (ACE) are effective treatments, but are time-consuming and difficult to perform independently. The majority of children using TAI (72%) and ACE (63%) never went to the toilet alone to empty their bowels. As children achieving independence on the toilet reported higher quality of life, efforts to support independence are beneficial. Continent, self-managing children with healthy kidneys enjoy high quality of life and contribute more fully to society. Therefore, further research is required to investigate and develop existing and new technologies and methods that mitigate the problems related to SD, and to make them accessible to all children with spinal dysraphism. Under de senaste 50 åren har det skett en enastående utveckling av möjligheterna för barn som föds med ryggmärgsbråck. Tidigare har majoriteten av barn med ryggmärgsbråck avlidit redan som spädbarn men idag överlever de flesta till vuxen ålder. Utan aktiva insatser och uppföljning är dock risken för medicinska problem och allvarlig påverkan på livet mycket stor. Nu när nästan alla barn överlever ligger fokus på att också nå okad livskvalitet och självständighet för personer med ryggmärgsbråck. Nästan alla med ryggmärgsbråck måste hantera en allvarlig påverkan på blåsan och tarmen med risk för njurskador, inkontinens och förstoppning. I avhandlingens två första studier värderade vi en metod att, med minimalt obehag för barnet, bedöma blåsfunktionen. Detta för att kunna skilja ut de barn som behöver genomgå mer avancerade undersökningar och få hjälp med blåstömningen genom täta tappningar med kateter, sa kallad ren intermittent kateterisering, RIK. När vi jämförde resultatet av testet för 50 nyfödda med ryggmärgsbråck med samma undersökning av 50 friska nyfödda fann vi stora skillnader. Mest tydligt var att de flesta nyfödda med ryggmärgsbråck (69%) men inga friska nyfödda läckte urin när man tryckte över blåsan. Av nyfödda med ryggmärgsbråck kissade de flesta (74%) inte med stråle vilket alla friska nyfödda gjorde. Att inte kissa med stråle talade också starkt för att barnet skulle komma att behöva hjälp med RIK för att tomma blåsan vid ett ars ålder, och då sannolikt livet ut. Sammantaget visade avhandlingens två första arbeten att den metod för bedömning av blåsfunktion vi undersökt kan användas för att styra uppföljning och behandling av nyfödda med ryggmärgsbråck. Avhandlingens tredje studie visade att aktiv uppföljning av barnen enligt ett nationellt vårdprogram lyckades förhindra njurskador hos de flesta, men att höga tryck i urinblåsan och återkommande urinvägsinfektioner ökade risken för skador. Även familjernas förmåga att i en pressad vardag klara av att genomföra de ofta krävande behandlingar och undersökningar som rekommenderas verkade vara viktig för att förhindra njurskador. Stöttning av familjerna är därför viktig. Avhandlingens fjärde arbete berörde tarmen som nästan alltid är påverkad vid ryggmärgsbråck, med risk för svår förstoppning och avföringsläckage. Detta har påtaglig påverkan på barnen och deras familjer. En tredjedel av de 107 familjerna i vår enkätundersökning i Sverige och Norge (barn 6-16 år) beskrev att man fått avstå från aktiviteter såsom resor på grund av barnets tarmproblem och de barn som hade avföringsläckage rapporterade tydligt lägre livskvalitet än andra. Trots denna allvarliga påverkan finns det hittills inga studier som jämför de olika behandlingar som barnet kan använda. I vår enkät kartlade vi därför vilka metoder som användes och hur bra de fungerade. Vi ställde frågor till både barn och föräldrar, särskilt om avföringsläckage, hur nöjd man var med metoden, barnens livskvalitet och självständighet på toaletten. Det var utifrån svaren tydligt att båda de vanligaste typerna av tarmsköljning var effektiva men tidskrävande och svara för barn och ungdomar att klara att utföra på egen hand. Ingen metod visade sig överlägsen den andra men de barn som klarade att skota tarmtomningen själva skattade sin livskvalitet klart högre än övriga. Vi drar därför slutsatsen att det är viktigt att vårdpersonal diskuterar de olika behandlingsalternativen med barn och föräldrar, och tillsammans med dem väljer den metod som passar det enskilda barnet bäst. Då skapas bästa förutsättningar för att gemensamt arbeta vidare för att uppnå största möjliga självständighet. Självständiga individer, med friska njurar och utan urin- och avföringsinkontinens upplever högre livskvalitet och behöver mindre sjukvård och andra samhällsinsatser. Det behövs mer forskning för att utveckla existerande och nya metoder att hantera de allvarliga komplikationer som riskerar att drabba barn och vuxna med ryggmärgsbråck.

Download or read book Finding Your Business Mojo written by Kevin Gammie and published by . This book was released on 2016-09-29 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finding Your Business Mojo will get you focused: helping you find more ideal clients, improve your confidence and your time management. In 2012, reeling from the effects of GFC on the business I'd owned for 15 years, I'd had enough. Realising there must be a better way. I dedicated my time to understanding how small business owners could get their life back whilst growing their business, and the results were amazing: Architect 12 years - grows by 25% spending more time with family in 6 months IT Business owner 10+ years - stops working 60, 70+ hours and grows 20% Recruiter 18 months - Develops a game changer, adding $100k+ sales Cloud Integration Start-up - focused and profitable within 9 months From time to time we all fall from our path, lose our groove or just get stuck. If that sounds familiar and instead you'd like more focus, ideal clients and better time management creating the lifestyle you deserve, Finding Your Business Mojo will provide the framework and resources to do exactly that.

Download or read book Nimmer on Copyright written by Melville B. Nimmer and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: