Download or read book Muscular Dystrophy written by Gisela Gaina and published by BoD – Books on Demand. This book was released on 2020-12-23 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muscular Dystrophy - Research Update and Therapeutic Strategies is for students, researchers, and clinicians interested in muscular dystrophies who want to improve their knowledge of these complex genetic diseases. The book includes information about the genetics of various types of muscular dystrophies as well as explores new and current therapeutic strategies that aim to ameliorate symptoms and improve patients’ quality of life and life expectancy. In addition, this book reviews information on current clinical trials for muscular dystrophies and presents a framework for what to consider during the design of these trials.
Download or read book Translational Research in Muscular Dystrophy written by Shin'ichi Takeda and published by Springer. This book was released on 2016-02-02 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent advances in translational research on muscular dystrophy (MD) to physicians and researchers, including cutting-edge research on the disease such as regenerative medicine, next-generation DNA sequencing, and nucleic acid therapies. It also describes the current systems for clinical trials and MD patient databases, resources, which will support the early realization of clinical application and improve patients’ quality of life. MD is the one of the most widely known inherited neuromuscular diseases and is classified into diverse types by symptoms, age of onset, mode of inheritance, and clinical progression. With the development of molecular biology, the occurrence mechanisms of each type of MD are gradually being elucidated. Although there is no known permanent cure yet, the stage of treatment research has now advanced to clinical trials.
Download or read book Trends in Muscular Dystrophy Research written by V. N. Burgess and published by Nova Science Publishers. This book was released on 2005 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The muscular dystrophies (MD) are a group of genetic diseases characterised by progressive weakness and degeneration of the skeletal muscles which control movement. There are many forms of muscular dystrophy, some noticeable at birth (congenital muscular dystrophy), others in adolescence (Becker MD), but the 3 most common types are Duchenne, facioscapulohumeral, and myotonic. These three types differ in terms of pattern of inheritance, age of onset, rate of progression, and distribution of weakness. Duchenne MD primarily affects boys and is the result of mutations in the gene that regulates dystrophin -- a protein involved in maintaining the integrity of muscle fibre. Onset is between 3-5 years and progresses rapidly. Most boys become unable to walk at 12, and by 20 have to use a respirator to breathe. Facioscapulohumeral MD appears in adolescence and causes progressive weakness in facial muscles and certain muscles in the arms and legs. It progresses slowly and can vary in symptoms from mild to disabling. Myotonic MD varies in the age of onset and is characterised by myotonia (prolonged muscle spasm) in the fingers and facial muscles; a floppy-footed, high-stepping gait; cataracts; cardiac abnormalities; and endocrine disturbances. Individuals with myotonic MD have long faces and drooping eyelids; men have frontal baldness. This volume presents leading-edge research results on MD.
Download or read book Duchenne Muscular Dystrophy written by Camilla Bernardini and published by Humana Press. This book was released on 2017-10-25 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores experimental approaches used to study Duchenne muscular dystrophy (DMD), an X-linked degenerative skeletal muscle disease caused by mutations in the dystrophin gene. Including the latest progress and scientific achievements, the book covers recent discoveries achieved through in vivo gene editing which have proven to be promising in restoring dystrophin expression, at least in ameliorating skeletal muscle symptoms, and the contents focus on “Omics” techniques in gene expression, protein expression, miRNAs, and long non-coding RNA analysis, as well as experimental studies of the structural/functional changes affecting the skeletal and cardiac muscles and ongoing preclinical studies and clinical trials. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Duchenne Muscular Dystrophy: Methods and Protocols serves as a guide for researchers exploring the complicated nature of dystrophin in the hope of helping the victims of this disorder.
Download or read book Muscular Dystrophy written by National Institute of Neurological Diseases and Stroke and published by . This book was released on 1971 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Muscular Dystrophy Research written by Corrado Angelini and published by . This book was released on 1980-01-01 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Muscular Dystrophy Research written by Corrado Angelini and published by . This book was released on 1991 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, if not only in the last five years, an unprecedented advance occured in the understanding of the primary defect involved in Duchenne muscular dystrophy. As a consequence, new promising lines and trends of research emerged: molecular diagnosis by use of anti-dystrophin antibodies or by DNA probes and those more strictly dealing with the perspectives of therapy, including myoblast transfer and gene therapy. The many outstanding papers which appear in this volume document the incredible power of modern tools of medical research in unravelling the complexity of the pathology and in finding new therapeutical strategies.
Download or read book The NINCDS Muscular Dystrophy and the Neuromuscular Disorders Research Program written by National Institute of Neurological and Communicative Disorders and Stroke and published by . This book was released on 1975 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Research in Muscular Dystrophy The Proceedings of the Third Symposium on Current Research in Muscular Dystrophy 8th 9th January 1965 Edited by the Members of the Research Committee of the Muscular Dystrophy Group With Illustrations written by Central Council for the Disabled (LONDON). Muscular Dystrophy Group. Symposium on Current Research in Muscular Dystrophy and published by . This book was released on 1965 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Research in Muscular Dystrophy The Proceedings of the Second Symposium on Current Research in Muscular Dystrophy Held at the National Hospital Queen Square London 3rd 4th January 1963 Edited by the Members of the Research Committee of the Muscular Dystrophy Group With Illustrations written by Central Council for the Disabled (LONDON). Muscular Dystrophy Group. Symposium on Current Research in Muscular Dystrophy and published by . This book was released on 1963 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Duchenne Muscular Dystrophy written by Camilla Bernardini and published by Humana. This book was released on 2018-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores experimental approaches used to study Duchenne muscular dystrophy (DMD), an X-linked degenerative skeletal muscle disease caused by mutations in the dystrophin gene. Including the latest progress and scientific achievements, the book covers recent discoveries achieved through in vivo gene editing which have proven to be promising in restoring dystrophin expression, at least in ameliorating skeletal muscle symptoms, and the contents focus on “Omics” techniques in gene expression, protein expression, miRNAs, and long non-coding RNA analysis, as well as experimental studies of the structural/functional changes affecting the skeletal and cardiac muscles and ongoing preclinical studies and clinical trials. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Duchenne Muscular Dystrophy: Methods and Protocols serves as a guide for researchers exploring the complicated nature of dystrophin in the hope of helping the victims of this disorder.
Download or read book Muscular Dystrophy written by Paula Johanson and published by The Rosen Publishing Group, Inc. This book was released on 2008-08-15 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muscular dystrophy (MD) is a genetic disorder that gradually weakens a persons muscles. It is caused by missing or incorrect genetic information in the bodys cells. The persons body is unable to make the proteins needed to build and maintain healthy muscles. Although there is no cure for muscular dystrophy, researchers are learning about how to prevent and treat the condition. Doctors have learned a great deal about how to improve muscle and joint function and how to slow the deterioration of muscles. Their goal is to help children, teenagers, and adults with muscular dystrophy live active and independent lives for as long as possible. This book delves into the history of the disorder, the genetic basis of MD, the main types of MD, and living with MD and suggests some coping strategies. It also explores diagnostic tests for MD, genetic research, and the promising effects of gene therapy.
Download or read book Muscular Dystrophy written by Raymond A. Huml and published by Springer. This book was released on 2015-07-16 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical and concise guide offers an overview of muscular dystrophy's complicated features, treatment options and general resources. New treatments and a greater understanding of proteins and structures associated with MD are discussed along with long term patient care. Also included are clinical and developmental challenges within the current regulatory landscape and recent scientific and clinical advances. Muscular Dystrophy offers clinicians, researchers, pharmaceutical executives and patient advocacy groups an easy-to-read reference that provides the necessary perspectives of the care giver and patient.
Download or read book Muscular Dystrophy Research written by and published by . This book was released on 1991 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Muscular Dystrophies Advances in Research and Treatment 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muscular Dystrophies: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Muscular Dystrophies in a compact format. The editors have built Muscular Dystrophies: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Muscular Dystrophies in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Muscular Dystrophies: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book A Report on the Liberty Muscular Dystrophy Research Foundation Symposium on Muscular Dystrophy October 4 and 5 1963 Etc written by Liberty Muscular Dystrophy Research Foundation (HOUSTON) and published by . This book was released on 1964 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Research in Muscular Dystrophy written by Symposium on Current Research in Muscular Dystrophy, 3D, Londres,1965 and published by . This book was released on 1965 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt:
