Download or read book Multipurpose Prevention Technologies for HIV STIs Pregnancies written by Barbara Friedland and published by Frontiers Media SA. This book was released on 2024-02-01 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globally, women of reproductive age face two overlapping issues that have a significant impact on their health and well-being: unintended pregnancy and sexually transmitted infections (STIs), including HIV. A growing body of research indicates that the majority of women across geographies, ages, racial and ethnic backgrounds would prefer a multipurpose prevention technology (MPT) that combines protection against pregnancy and HIV/STIs versus individual products for contraception and disease prevention. Currently, male and female condoms are the only available MPTs. A wider range of MPT options will help women select methods that they are less apt to discontinue, as well as increase uptake by first-time users. A number of MPT candidates – intravaginal rings (IVRs), oral tablets, vaginal fast dissolving inserts (FDIs), implants, injectables and microarray patches (MAPs) are in various stages of development. The goal of this Research Topic is to invigorate continued development on MPTs by providing the most up-to-date research on specific products in development, identifying research gaps related to the field overall, and prepare for introduction into programs and healthcare systems. Our broad approach will cover formulation science, clinical trials, sociobehavioral research, and implementation science to present the latest thinking in all areas of MPT development from “bench to bedside.”
Download or read book Multipurpose Prevention Technologies Call for Innovative Strategies to Address Critical Priorities and Gaps written by Bethany Young Holt and published by Frontiers Media SA. This book was released on 2024-05-31 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The HIV/sexually transmitted infection (STI) syndemics and the unmet need for modern contraceptive methods continue to pose significant health risks for women and other people worldwide. As awareness of the need to address these interlinked risks has increased, the need for new technologies that combine protection against unintended pregnancy, HIV and other STIs is a growing research priority. Multipurpose Prevention Technologies (MPTs) are products that simultaneously prevent HIV, other STIs, and/or unintended pregnancy. They have power to revolutionize women's health by providing prevention for multiple indications.
Download or read book Sexually Transmitted Infections written by National Academies of Sciences, Engineering, and Medicine and published by . This book was released on 2021-12-24 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: One in five people in the United States had a sexually transmitted infection (STI) on any given day in 2018, totaling nearly 68 million estimated infections. STIs are often asymptomatic (especially in women) and are therefore often undiagnosed and unreported. Untreated STIs can have severe health consequences, including chronic pelvic pain, infertility, miscarriage or newborn death, and increased risk of HIV infection, genital and oral cancers, neurological and rheumatological effects. In light of this, the Centers for Disease Control and Prevention, through the National Association of County and City Health Officials, commissioned the National Academies of Sciences, Engineering, and Medicine to convene a committee to examine the prevention and control of sexually transmitted infections in the United States and provide recommendations for action. In 1997, the Institute of Medicine released a report, The Hidden Epidemic: Confronting Sexually Transmitted Diseases. Although significant scientific advances have been made since that time, many of the problems and barriers described in that report persist today; STIs remain an underfunded and comparatively neglected field of public health practice and research. The committee reviewed the current state of STIs in the United States, and the resulting report, Sexually Transmitted Infections: Advancing a Sexual Health Paradigm, provides advice on future public health programs, policy, and research.
Download or read book Multipurpose Prevention Technologies for Reproductive and Sexual Health written by Alan Stone and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Global statistics on unplanned pregnancies, abortions and STIs show that unprotected sex is still widely practised. More needs to be done to provide women and men with a wider choice of convenient protective options. To address this need, international efforts are focusing on developing multipurpose prevention technologies (MPTs) that address two or more indications simultaneously. These technologies would have significant advantages over single-indication products. They include inter alia novel barrier devices, drugs administered either as oral tablets or vaginal/rectal gels, drugs used in combination with medical devices, and genetically engineered organisms which secrete antimicrobial substances. As an example of progress in the MPT field, this paper describes an on-demand contraceptive/antimicrobial vaginal gel, Amphora (previously known as Acidform), now in an advanced stage of development. Clinical trials are currently being planned to find out whether this product's promising antimicrobial profile translates into protective and preventive choices.
Download or read book Trichomonads Parasitic in Humans written by B.M. Honigberg and published by Springer. This book was released on 2011-09-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: G. Piekarski appears not to have been brought home to at Forty years have passed since Trussent pub least some clinicians. Of special importance in lished an important book in the English lan this connection are T. vaginalis and Pentatri guage on Trichomonas vaginalis Donne and uro chomonas hominis (Davaine), the intestinal tri genital trichomoniasis. During the intervening chomonads of many mammalian species, in four decades, much information has been accu cluding humans. Some practitioners still tell mulated on trichomonads parasitic in humans their patients about the possibility of an intesti and on the diseases they cause. In light of this, nal origin of trichomonal infection of the uro many parasitologists and clinicians believe that the time has come for a complete review, in genital tract. book form, of various aspects of these parasites Trichomonas vaginalis infection of new and of the trichomonad parasitemias. This need borns, infants, and young children constitutes has been further reinforced by the finding that, an interesting, although not extensively pur despite the use of effective anti trichomonal sued, area of investigation. For hitherto incom drugs during the past years, the prevalence of pletely understood reasons, the period of preg human urogenital trichomoniasis, the world's nancy appears to favor the increase of most common sexually transmitted disease, has symptomatic trichomoniasis; there is, there been increasing significantly. As might have fore, little doubt that infants can be infected been expected, therefore, discussion of various during birth.
Download or read book Strange Bedfellows written by Ina Park and published by Flatiron Books. This book was released on 2021-02-02 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Joyful and funny . . . Park uses science, compassion, humor, diverse stories and examples of her own shame-free living to take the stigma out of these infections." —The New York Times With curiosity and wit, Strange Bedfellows rips back the bedsheets to expose what really happens when STDs enter the sack. Sexually transmitted diseases have been hidden players in our lives for the whole of human history, with roles in everything from World War II to the growth of the Internet to The Bachelor. But despite their prominence, STDs have been shrouded in mystery and taboo for centuries, which begs the question: why do we know so little about them? Enter Ina Park, MD, who has been pushing boundaries to empower and inform others about sexual health for decades. With Strange Bedfellows, she ventures far beyond the bedroom to examine the hidden role and influence of these widely misunderstood infections and share their untold stories. Covering everything from AIDS to Zika, Park explores STDs on the cellular, individual, and population-level. She blends science and storytelling with historical tales, real life sexual escapades, and interviews with leading scientists—weaving in a healthy dose of hilarity along the way. The truth is, most of us are sexually active, yet we’re often unaware of the universe of microscopic bedfellows inside our pants. Park aims to change this by bringing knowledge to the masses in an accessible, no-nonsense, humorous way—helping readers understand the broad impact STDs have on our lives, while at the same time erasing the unfair stigmas attached to them. A departure from the cone of awkward silence and shame that so often surrounds sexual health, Strange Bedfellows is the straight-shooting book about the consequences of sex that all curious readers have been looking for.
Download or read book Integration of HIV Prevention with Sexual and Reproductive Health Services written by Renee Heffron and published by Frontiers Media SA. This book was released on 2023-03-13 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Implantable Technologies written by Ved Srivastava and published by Royal Society of Chemistry. This book was released on 2021-10-20 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implantable technologies allow for a sustained control over the release of pharmaceuticals into the bloodstream thereby achieving a controlled concentration with the potential to minimise side-effects while increasing patient compliance. Significant progress has been made in various alternative implantable delivery technologies, notably in intraocular and subcutaneous devices. Despite success in research and clinical studies, long-term clinical efficacy may be more limited and different aspects related to drug development and commercialization using these technologies are not well understood or practiced in the commercial setting. This book provides a comprehensive and cohesive picture of the latest in the field while also outlining the opportunities and challenges in implantable technology. Implantable Technologies: Pepties and Biologic Drug Development is an ideal reference for any postgraduate or researcher interested in utilising implantable technologies and novel routes of drug administration. The book will also be of interest to those involved in formulation and clinical application for a wide array of disease areas in addition to more established paradigms such as diabetes and pain management.
Download or read book Anti HIV Activity of the Human Antimicrobial Peptide LL 37 and Its Engineered Peptide 17BIPHE2 written by Ana Vera-Cruz and published by . This book was released on 2022 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Unwanted pregnancies and sexually transmitted infections (STIs) are major health concerns of women worldwide. These concerns have prompted efforts to develop Multipurpose Prevention Technologies (MPTs), which simultaneously provide contraception and prevent STIs, including HIV. LL-37, the only human cathelicidin and an effective spermicide on human sperm, has broad antimicrobial activity including in vitro activity against HIV. 17BIPHE2 is a truncated LL-37 peptide, engineered to contain 5 unnatural residues, thus limiting its protease degradation within vaginal fluid. Hence, this antimicrobial peptide (AMP) represents a promising MPT agent. It was therefore hypothesized that these peptides would be inhibitors of HIV infection in cell lines, PBMC, and CD4+ T cells. In the chronically infected ACH-2 cell line, there was significant reduction in p24 production when cells were treated with 17BIPHE2, but not LL-37. When 17BIPHE2 was pre-incubated with HIV prior to infection and present during infection, viral replication decreased in the TZM-bl reporter cell line, but this result was not recapitulated in the primary activated cells, PBMCs nor isolated CD4+ T cells. Conversely, pre-incubation of 17BIPHE2 with target cells prior to infection significantly inhibited HIV infection in a dose-dependent manner. Therefore, 17BIPHE2 may act on the cell or on the virus/cell interaction rather than on the virus itself to inhibit HIV infection.
Download or read book Managing Complications in Pregnancy and Childbirth written by and published by World Health Organization. This book was released on 2003 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emphasis of the manual is on rapid assessment and decision making. The clinical action steps are based on clinical assessment with limited reliance on laboratory or other tests and most are possible in a variety of clinical settings.
Download or read book HIV AIDS written by Nancy Dumais and published by BoD – Books on Demand. This book was released on 2017-02-22 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: With increasing efficacy of antiretroviral therapy, HIV/AIDS has shifted from a disease with high mortality to a chronic illness with substantial longevity. However, researchers, physicians and social workers still face many challenges, and it is important to raise awareness on several aspects that people living with HIV/AIDS have to deal in their daily lives. This book has assembled an array of chapters on the medical, social and economic aspects of HIV/AIDS. The chapters were written by experts from around the globe reflecting the importance of the topic. This book will be of great interest not only to graduate students but also to active academics and practitioners.
Download or read book Sexually Transmitted Infections Among Adolescents written by Karl L. Dehne and published by . This book was released on 2005 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document presents a comprehensive literature review, documenting existing experience with the provision of services for sexually transmitted infections (STIs) to adolescents. It draws from programme experience worldwide, including the following service delivery models: public and nongovernmental organization health services which have been made adolescent-friendly, sexual and reproductive health clinics and multipurpose centres for young people, school-based or school-linked services, and community-based and private sector services.
Download or read book Sexually Transmitted Diseases written by National Center for Prevention Services (U.S.). Division of STD/HIV Prevention and published by . This book was released on 2002 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nanotechnology and Drug Delivery written by Rakesh K. Sindhu and published by CRC Press. This book was released on 2024-02-06 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of the rapidly developing field of nanotechnology applications in drug delivery systems and covers a variety of technologies and materials that help in achieving vast variation in the particle size needed in technology and drug delivery-based research. It discusses nanotechnology’s use in healthcare for the development of target-specific drug therapy and smart field systems and in the pharmaceutical industry to improve the quality, efficacy, and shelf life of medicines. Bringing together principles, theory, practice, and applications of nanotechnology, the book is a useful resource for chemists, physicists, biomedical researchers, engineers, advanced undergraduate and graduate-level students in nanotechnology, researchers in pharmaceutical sciences, chemistry, biology, biotechnology engineering, and general readers in nanotechnology.
Download or read book The Impact of HIV AIDS on Education and Institutionalizing Preventive Education written by Roy A. Carr-Hill and published by . This book was released on 2002 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the impact of HIV/AIDS on education in sub-Saharan African countries. It looks at the situation at both macro and micro levels and emphasizes the need to react quickly and to institutionalize the response of education systems to the negative consequences of the pandemic. Drawing on studies of a few countries in sub-Saharan Africa, the first part of the book discusses the practicability of implementing a range of indicators for monitoring the impact of HIV/AIDS, specifically on the demand for supply, management, and quality of education at all levels. It underlines the difficulties of assessing and monitoring the impact on demand, supply, and quality in many of the worst affected countries in Africa. The second part focuses on the essential role that the education system has to play in preventing the expansion and mitigating the impact of the epidemic. A range of responses is developed, drawing on the experience of various national and international organizations. This part also presents an overview of the education system in several countries that have attempted programs to impart life skills to children and young people. It considers the problems of evaluating such programs in light of cost effectiveness. (Author/WFA).
Download or read book AIDS and Social Policy in China written by Joan Kaufman and published by BRILL. This book was released on 2020-10-26 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first English language book on China’s AIDS epidemic provides a picture of the current state of the epidemic, a social science and interdisciplinary perspective on gaps in the response, and a blueprint for needed actions. The book’s editors are leading experts on China’s AIDS epidemic, health and political systems. Contributors comprise some of the world’s leading Chinese and international researchers, policy-makers, and civil society representatives working on HIV/AIDS in China. The multi-disciplinary work provides a critically needed social science perspective and analysis of the epidemic, offers a framework for thinking about the spread of HIV in China, and includes suggestions for an effective policy response that also addresses social determinants.
Download or read book Handbook of Mucosal Immunology written by and published by Academic Press. This book was released on 2012-12-02 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers have recently made tremendous progress in the area of mucosal immunology, greatly increasing our understanding of the common mucosal immune system, mucosal infections, and oral immunization. However, thisresearch has not previously been made available in a single work. In its large 81/2"x 11"format, Handbook of Mucosal Immunology covers the entire spectrum of mucosal immunity and is organized in two main sections to present the basic biology of the common mucosal immune system and the immune responses of the mucosae.The first section provides an introduction and historical perspective of the mucosal immune system and includes comprehensive discussion of the development and physiology of mucosal defense. It discusses such topics as the structure and function of themucosal epithelium, characteristics of mucosal-associated lymphoid tissue (MALT), Peyers patches, and concepts of mucosal vaccines. The second section focuses on the secretory immune system with special reference to mucosal diseases in the digestive (GALT), respiratory (BALT), and genitourinary tracts. This information is especially important in light of the current interest in the mechanisms, transmission, and prevention of infectious diseases such as AIDS, hepatitis, and tuberculosis.Virtually all chapters have been authored by the original investigators responsible for key observations on which current concepts are based. This handbook will be an invaluable resource for a diverse group of both researchers and practicing clinicians.Molecular biologists, immunologists, veterinarians, public health workers, physicians in specialties from pediatrics to pulmonology, and graduate students of mucosal immunology will all find this handbook the most complete work on the subject.
