Download or read book Multimodal Multispectral Optical Endoscopic Imaging for Biomedical Applications written by Kevin Rongsheng Koh and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy written by Dale Jonathan Waterhouse and published by Springer. This book was released on 2019-07-09 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis describes the design, development, characterisation and clinical translation of three novel devices for optical endoscopic imaging. Over the past decade, rapid innovation in optics and photonics has led to the availability of low-cost and high-performance optical technologies that can be exploited for biomedical applications, but relatively few have been translated into clinic. The work presented outlines for the first time, a comprehensive analysis of the common barriers and unique challenges associated with the translation of optical imaging techniques. To assist developers streamline translation of optical imaging devices in future, a roadmap to clinical translation is outlined, and key translational characteristics are defined. Guided by these, subsequent development of endoscopic devices resulted in preparation and approval of endoscopes for first in human trials in the oesophagus, for early detection of cancer, and in the brain, for delineation of tumour during surgical resection. The thesis culminates in the presentation of results from the first in human use of a compact multispectral endoscope for imaging endogenous tissue contrast in the oesophagus. With continuation of the work as outlined at the end of this thesis, the novel techniques described have the potential to improve the standard of care in their respective indications.
Download or read book Translational Multimodality Optical Imaging written by Fred S. Azar and published by Artech House. This book was released on 2008 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supported with 119 illustrations, this milestone work discusses key optical imaging techniques in self-contained chapters; describes the integration of optical imaging techniques with other modalities like MRI, X-ray imaging, and PET imaging; provides a software platform for multimodal integration; presents cutting-edge computational and data processing techniques that ensure rapid, cost-effective, and precise quantification and characterization of the clinical data; covers advances in photodynamic therapy and molecular imaging, and reviews key clinical studies in optical imaging along with regulatory and business issues.
Download or read book Biomedical Optical Imaging Technologies written by Rongguang Liang and published by Springer Science & Business Media. This book was released on 2012-09-21 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to design of biomedical optical imaging technologies and their applications. The main topics include: fluorescence imaging, confocal imaging, micro-endoscope, polarization imaging, hyperspectral imaging, OCT imaging, multimodal imaging and spectroscopic systems. Each chapter is written by the world leaders of the respective fields, and will cover: principles and limitations of optical imaging technology, system design and practical implementation for one or two specific applications, including design guidelines, system configuration, optical design, component requirements and selection, system optimization and design examples, recent advances and applications in biomedical researches and clinical imaging. This book serves as a reference for students and researchers in optics and biomedical engineering.
Download or read book Endoscopic Diagnostics in Biomedicine written by N. Sujatha and published by Momentum Press. This book was released on 2019-03-04 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concise, yet comprehensive, coverage of various endoscopic forms as provided in this book will help the reader generate new knowledge in this field. Endoscopy has been in practice for many years in diagnostic medicine. From a simple image collection device, the endoscope has grown into an instrument that incorporates multiple imaging modalities to extract structural and functional information from different parts of the human body. Multimodality endoscopes are discussed in detail in this book, along with their clinical applications. The book is intended for graduate-level students as a quick reference to understand the evolving trends in endoscopic design research. The challenges that remain unaddressed could potentially be explored by biomedical researchers to advance this technology to realize the concept of optical biopsy during routine endoscopic examinations. The book portrays the endoscope as a purely optical instrument, and hence hybrid modes of endoscopic imaging are not covered.
Download or read book Imaging Through Optical Multimode Fiber written by Szu-Yu Lee and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical imaging in biomedicine provides pathophysiological information with high resolution, high speed, and minimal invasiveness. Endoscopy in particular has revolutionized healthcare diagnosis and treatment as well as biological research by offering visual access to otherwise unreachable remote tissues. However, existing endoscopic modalities face fundamental limitations in their designs that prohibit miniaturization to below a few millimeters in diameter, which would enable imaging through any natural or artificial lumen and thus unprecedented opportunities. This predicament and unmet medical needs such as deep-brain imaging, imaging-guided needle biopsy, and imaging-guided micro-surgery for new and scalable endoscope designs have motivated the concept of utilizing a single optical multimode fiber (MMF) as a stand-alone image conduit. MMF is fascinating as an optical waveguide attributed to its ultra-small footprint, high data throughput, low cost, and flexibility. Nevertheless, the mode mixing and dispersion effects inherent to MMF are technical barriers to its ability to relay clear images; optical propagation through a short length of MMF scrambles an image completely. The focus of this dissertation research is therefore to study waveguide physics of MMF and to innovate powerful computational methods as compensatory strategies that enable high fidelity imaging and sensing through the fiber: We developed numerical simulation toolboxes and experimental measurement systems to characterize bi-directional light transport through MMF; By modeling the light transmission through MMF and sample interaction with matrix operations, we demonstrated three-dimensional (3D) label-free multi-modal imaging based on computational reconstruction; To facilitate multi-spectral and broadband operations with MMF, we established a parametric dispersion model for efficient fiber calibration across a broad spectrum; The spatio-temporal modes within the MMF can be conveniently leveraged for depth sensing, where we created a high-resolution and long-range axial profiling system using MMF; Finally, we showed a proximal MMF calibration method for implementing flexible MMF-based endoscopes by exploiting the waveguide physics and numerical optimization.
Download or read book Diagnostic Endoscopy written by Haishan Zeng and published by Taylor & Francis. This book was released on 2013-12-09 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining a professional development course on diagnostic endoscopy from SPIE (the international society advancing light-based research) and the authors’ graduate course on biomedical optics, this work is written for researchers in medical optics and biomedical engineering as well as graduate medical optics students. It uses extensive examples/case studies to familiarize readers with the basics of endoscopic optics, the pros and cons of white light endoscopy and fluorescence endoscopy for diagnostic applications, and various microscopic endoscopy imaging modalities. It covers basic optics, details of design and biomedical uses, as well as microscopic endoscopy, and endoscopic spectroscopy.
Download or read book Concept for a Multi modal Endoscopic Imaging System written by Marc Blattmann and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Multimodal Optical Diagnostics of Cancer written by Valery V. Tuchin and published by Springer Nature. This book was released on 2020-10-23 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth description and discussion of different multi-modal diagnostic techniques for cancer detection and treatment using exact optical methods, their comparison, and combination. Coverage includes detailed descriptions of modern state of design for novel methods of optical non-invasive cancer diagnostics; multi-modal methods for earlier cancer diagnostic enhancing the probability of effective cancer treatment; modern clinical trials with novel methods of clinical cancer diagnostics; medical and technical aspects of clinical cancer diagnostics, and long-term monitoring. Biomedical engineers, cancer researchers, and scientists will find the book to be an invaluable resource. Introduces optical imaging strategies; Focuses on multimodal optical diagnostics as a fundamental approach; Discusses novel methods of optical non-invasive cancer diagnostics.
Download or read book Optical Imaging for Biomedical and Clinical Applications written by Ahmad Fadzil Mohamad Hani and published by CRC Press. This book was released on 2017-10-30 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical imaging is a rapidly emerging imaging technique that has been successfjully translated into biomedical applications ranging from clinical diagnosis to molecular biology. This book includes an introductory section to explore various optical imaging devices and their functionality and roles for biomedical applications such as dermatology and ophthalmology. Recent developments as exemplified with the authors research are explored in detail. In depth discussion of other disease conditions and their diagnosis with optical imaging techniques are also covered.
Download or read book Unconventional Optical Imaging for Biology written by Corinne Fournier and published by John Wiley & Sons. This book was released on 2024-05-21 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical imaging of biological systems has undergone spectacular development in recent years, producing a quantity and a quality of information that, just twenty years ago, could only be dreamed of by physicists, biologists and physicians. Unconventional imaging systems provide access to physical quantities – phase, absorption, optical index, the polarization property of a wave or the chemical composition of an object – not accessible to conventional measurement systems. To achieve this, these systems use special optical setups and specific digital image processing to reconstruct physical quantities. This field is also known as computational imaging. This book presents various non-conventional imaging modalities developed for the biomedical field: wave front analysis imaging, digital holography/tomography, optical nanoscopy, endoscopy and singlesensor imaging. Experimental setups and reconstruction algorithms are presented for each modality.
Download or read book Machine Learning and Hyper Spectral Imaging Multi Spectral Endoscopy in the Gastro Intestinal Tract Towards Hyper Spectral Endoscopy written by Martin Hohmann and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Biomedical Optics written by David A. Boas and published by CRC Press. This book was released on 2016-04-19 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamental
Download or read book Translational Multimodality Optical Imaging written by and published by . This book was released on 2008 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Optical Methods in Sensing and Imaging for Medical and Biological Applications written by Dragan Indjin and published by MDPI. This book was released on 2019-01-24 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Optical Methods in Sensing and Imaging for Medical and Biological Applications" that was published in Sensors
Download or read book Development of Quantitative Multi spectral Fluorescence Endoscopic Imaging for Early Cancer Detection written by Chenying Yang and published by . This book was released on 2014 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incidence of esophageal adenocarcinoma has been rising in the western world with a low 5 year survival rate of less than 15%, but it can be treated when diagnosed early. However, conventional white light endoscopy screening has significant limitations because early cancerous lesions usually lie flat on the tissue surface and do not differ in contrast relative to the surrounding area. In an effort to detect early stages of cancer, fluorescence molecular imaging was developed since it improves diagnostic sensitivity and specificity through targeted visualization of multiple biomarkers at the cellular and sub-cellular level. This dissertation presents technologies and algorithms developed for real-time wide-field and quantitative multispectral fluorescence endoscopy for image-guided biopsies and resections. The body of work includes a realistic Barrett's esophagus phantom model development with calibrated fluorescence targets, enhanced visualization and documentation of diagnostic endoscopic records through image mosaicking, real-time compensation for fluorophore emission cross-talk and mitigation of background tissue autofluorescence for high contrast and quantitative molecular endoscopy. Although the scanning fiber endoscope technology forms the basis of the multispectral imaging that was implemented, the concepts, algorithms, and techniques can be applied to a wide range of in vivo and in vitro imaging technologies. In the long term, this work provides the foundation and framework of computer-aided quantitative endoscopy for personalized diagnosis and treatment.
Download or read book Endoscopic Microscopy written by Guillermo J. Tearney and published by SPIE-International Society for Optical Engineering. This book was released on 2006 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of SPIE present the original research papers presented at SPIE conferences and other high-quality conferences in the broad-ranging fields of optics and photonics. These books provide prompt access to the latest innovations in research and technology in their respective fields. Proceedings of SPIE are among the most cited references in patent literature.
