Download or read book Moyamoya Disease Explored Through RNF213 written by Akio Koizumi and published by Springer. This book was released on 2017-02-21 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest findings on biological, epidemiological, and clinical investigations of RNF213, which is thought to be involved in many biological processes and plays a key role in cerebro- and cardiovascular disease . By discussing the epidemiology and genetic epidemiology of the disease with a particular focus on the molecular function of RNF213, research using animal models, diagnosis, therapy and clinical management around the world, this work makes a valuable contribution to the study of the disease.Moyamoya Disease Explored Through RNF213 is an indispensable resource for both beginning and experienced researchers, pediatricians, neurologists, and neurosurgeons who are seeking comprehensive information on adult and childhood stroke.
Download or read book Moyamoya Disease Current Knowledge and Future Perspectives written by Satoshi Kuroda and published by Springer Nature. This book was released on 2021-02-26 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together the latest knowledge on moyamoya disease, covering diagnostic criteria, status as a disease entity, genetic aspects, pathophysiology, novel neuroradiological findings, and surgical therapy. Information is also provided on recent basic and clinical research with the aim of identifying future perspectives on the disease. Since moyamoya disease was first reported in an English language article more than 50 years ago, our understanding of it has advanced considerably. Genetic and radiological analysis has delivered novel insights, and the latest multicenter studies are changing routine diagnosis and surgical therapy. The gene encoding the ring finger protein 213 (RNF213) has been identified as a susceptibility gene for moyamoya disease. Indications and procedures for surgical revascularization have been revised, with resultant improvements in outcomes, and studies performed over the past decade have provided new knowledge on the neuroradiological findings before and after surgery. In describing these advances, this book will be an invaluable asset for all general physicians, pediatricians, neurologists, radiologists, and neurosurgeons who care for patients with moyamoya disease across the world.
Download or read book New Developments in Understanding Brain and Cerebromicrovascular Aging Toward Prevention of Vascular Cognitive Impairment and Alzheimer s Disease written by Stefano Tarantini and published by Frontiers Media SA. This book was released on 2022-07-05 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Moyamoya Disease Update written by Byung-Kyu Cho and published by Springer Science & Business Media. This book was released on 2010-02-26 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Moyamoya disease (MMD) was first reported as a new entity among vascular disorders in 1957. Named for the abnormal vascular networks found around the occluded distal internal carotid artery, it is the most common pediatric cerebrovascular disease in East Asia. In recent years large amounts of data on MMD have been collected and important investigations have been carried out in Japan and Korea, even as the pathophysiology of the disease remains to be discovered. This monograph covers a diversity of topics and presents a systematic compilation of the data and current status of MMD in clinical practice and basic research. With contributions by more than 70 authors, the book includes sections on genetics, computational analysis of hemodynamic shear stress, new imaging techniques, and endovascular treatment of MMD, along with practical applications and future directions for gene and stem cell therapies. For neurosurgeons as well as neurologists and pediatricians, this volume will help lead to more efficient and informed management of MMD.
Download or read book The Smartbook of Neurosugery written by Elizabeth Ogando-Rivas and published by bohrpub. This book was released on with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been done thinking about the most common challenging situations and questions that come during the daily activities as a resident or young neurosurgeon. Introducing The Smartbook of Neurosurgery, is a concise, informative, useful, and evidence-based guide for residents, young neurosurgeons, and health care professionals interested in neurosurgery. - This book has been thought about the most common challenging situations and questions that come during the daily activities as a resident or young neurosurgeon. - This book contains over 2,000 questions divided into 8 chapters and these chapters include basic, translational, clinical, and surgical scenarios - The question and answer for the topics Neuroanatomy, Neurophysiology, neurological surgery, Neuropharmacology, Neuroradiology, cranial and brain surgery, Neuroradiology, Neuropathology, Neurology, Pediatric Neurosurgery, Spine Surgery, Peripheral Nerve, Tips and Tricks on the cranial approach, intracranial tumor neurosurgery, endoscopic neurosurgery, acromegaly, cerebrovascular surgery, and cranial trauma neurosurgery are clearly defined as The Smartbook of Neurosurgery. - This book represents a resource for on-the-fly consults on a busy hospital day, as a refresher for boards and to prepare medical students for their neurosurgical rotations or before getting into the residency.
Download or read book Moyamoya Disease 2nd edition written by Yuxiang Gu and published by Frontiers Media SA. This book was released on 2023-05-24 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Moyamoya disease (MMD) is a chronic cerebrovascular disease characterized by progressive stenosis of the arteries of the circle of Willis, and formation of a collateral vascular network at the base of the brain. Moyamoya syndrome is caused by numerous conditions, which lead to arterial occlusion of the circle of Willis and resultant collaterals reminiscent of moyamoya disease. Due to the diverse angioarchitecture and unknown influence factors, the hemodynamic disturbances of MMD/Moyamoya syndrome are complicated, and result in multimodal clinical manifestations including headache, cognitive impairment, seizures, TIA, infarction, and hemorrhage. Surgical revascularization has been proven as effective in decreasing incidence of long-term risk of stroke. However, occurrence of perioperative stroke and complications such as seizures and cerebral hyperperfusion syndrome are still unpredictable. In addition, many patients with cognitive impairment cannot benefit from surgical revascularization and the mechanism remains unclear. Thus, a series of studies focusing on the objective evaluation of MMD/Moyamoya syndrome are needed to help understand this complicated cerebrovascular disease and improve our treatment strategy. The goal of this Research Topic is to better understand the pathophysiological nature of MMD/Moyamoya syndrome through objective neuroimaging. We also aim to generate a reasonable and objective evaluation system for MMD/ Moyamoya syndrome and would like to understand the link between cognitive impairment and brain damage of MMD/Moyamoya syndrome though neuroimaging. Through these findings we also aim to improve the treatment strategy by understanding the pathophysiological link with relevant complications. Finally, we also aim to improve our understanding of the significance of perioperative management for patients with severe complications from the perspective of objective evaluation.
Download or read book NORD Guide to Rare Disorders written by National Organization for Rare Disorders and published by Lippincott Williams & Wilkins. This book was released on 2003 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: NORD Guide to Rare Disorders is a comprehensive, practical, authoritative guide to the diagnosis and management of more than 800 rare diseases. The diseases are discussed in a uniform, easy-to-follow format--a brief description, signs and symptoms, etiology, related disorders, epidemiology, standard treatment, investigational treatment, resources, and references.The book includes a complete directory of orphan drugs, a full-color atlas of visual diagnostic signs, and a Master Resource List of support groups and helpful organizations. An index of symptoms and key words offers physicians valuable assistance in finding the information they need quickly.
Download or read book PanVascular Medicine written by Peter Lanzer and published by Springer. This book was released on 2015-03-30 with total page 5004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular management and care has become a truly multidisciplinary enterprise as the number of specialists involved in the treatment of patients with vascular diseases has steadily increased. While in the past, treatments were delivered by individual specialists, in the twenty-first century a team approach is without doubt the most effective strategy. In order to promote professional excellence in this dynamic and rapidly evolving field, a shared knowledge base and interdisciplinary standards need to be established. Pan Vascular Medicine, 2nd edition has been designed to offer such an interdisciplinary platform, providing vascular specialists with state-of-the art descriptive and procedural knowledge. Basic science, diagnostics, and therapy are all comprehensively covered. In a series of succinct, clearly written chapters, renowned specialists introduce and comment on the current international guidelines and present up-to-date reviews of all aspects of vascular care.
Download or read book Intracranial Atherosclerosis Pathophysiology Diagnosis and Treatment written by J.S. Kim and published by Karger Medical and Scientific Publishers. This book was released on 2016-12-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intracranial atherosclerosis is a leading cause of stroke in Asians and Africans. As these ethnic groups account for more than 70% of the world’s population, it is in fact the major cause of ischemic stroke worldwide. This timely book provides readers with up-to-date knowledge of intracranial atherosclerosis, covering vascular anatomy, pathology, epidemiology, stroke mechanisms and syndromes, diagnostic methods as well as treatment strategies such as antithrombotics, angioplasty/stenting and surgery. Furthermore, nonatherosclerotic intracranial arterial diseases like Moyamoya disease, dissection, vasculitis and other miscellaneous disorders are extensively discussed. Experts from both East and West present the latest findings from cutting-edge research and discuss controversial topics from different yet balanced points of view, allowing readers to form their own unbiased opinion on these issues. With this approach, the book serves as a useful and stimulating guide on the diagnosis and management of intracranial atherosclerosis for neurologists, neurosurgeons, neuroradiologists and vascular interventionists.
Download or read book Introduction to Vascular Neurosurgery written by Justin R. Mascitelli and published by Springer Nature. This book was released on 2022-01-12 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to cover the majority of neurovascular diseases and management. The first section reviews neurovascular anatomy, the basics of angiography, and the basics of craniotomies for neurovascular diseases. Next, an entire section is devoted to intracranial aneurysms, covering the natural history, subarachnoid hemorrhage, endovascular management, microsurgical management, and vasospasm. Following this, a number of chapters are devoted to stroke including natural history, mechanical thrombectomy, intracranial stenosis, Moyamoya disease, bypass surgery, vertebrobasilar insufficiency, intracerebral hemorrhage, sinus thrombosis, and the surgical and endovascular management of extracranial carotid disease. Next, the text covers vascular malformations including arteriovenous malformation, arteriovenous fistulas, carotid cavernous fistulas, vein of Galen malformations, spinal malformations, and cavernous malformations. Finally, the book discusses a few miscellaneous topics including more recent advances in neurovascular care such as venous sinus stenting for idiopathic intracranial hypertension and middle meningeal artery embolization for subdural hematoma. Written by experts in the field, Introduction to Vascular Neurosurgery provides a comprehensive summary of neurovascular disease and management. The book can be used as a daily reference and serves as a trusted resource for medical students, residents, fellows, and young attendings.
Download or read book Stroke Revisited Hemorrhagic Stroke written by Seung-Hoon Lee and published by Springer. This book was released on 2018-09-05 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents state of the art knowledge on hemorrhagic stroke in a unique organizational style. All aspects are covered, including risk factors, pathophysiology, diagnostic modalities, treatment, and prevention. Individual procedures and issues are fully discussed with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to retrieve fundamental information quickly. Furthermore, in an accompanying overview diagnostic and therapeutic processes are dynamically described in a time sequence mirroring real practice. The recent striking advances in brain imaging have resulted in a better understanding of the causes and pathophysiology of hemorrhagic stroke, and management has been enhanced by a variety of surgical techniques, intensive monitoring, and administration of novel medical treatment. Against this background, it is timely to summarize current understanding of hemorrhagic stroke and its management from a practical perspective. This textbook will be invaluable for stroke physicians, surgeons, and students seeking to acquire up-to-date knowledge on the subject.
Download or read book Neurovascular Imaging written by Luca Saba and published by Springer. This book was released on 2016-01-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Neurology, Vascular Neurosurgery and Interventional Neuroradiology are independent fields with dedicated Training Programs. Neuroimaging, and in particular what we call "Neurovascular Imaging" is a unifying factor which can be considered the intersection of these three medical specialties. With this book we aim to cover thoroughly the imaging techniques, potentialities, and present and future applications as applied to all the vascular diseases of the central nervous system from the imaging point of view. This book will comprise eight main sections: (1) The Basics, (2) Arteries of the Head and Neck (3) The basics of Intracranial Arteries (4) Diseases of the vessels (5) Stroke Imaging (6) Veins Imaging (7) Spine Imaging (8) Pediatrics.
Download or read book Vascular neurosurgery and microneuroanatomy written by Feres Chaddad-Neto and published by Frontiers Media SA. This book was released on 2023-07-21 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Warlow s Stroke written by Graeme J. Hankey and published by John Wiley & Sons. This book was released on 2019-04-15 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical textbook, based on a problem-oriented workflow, that will improve patients' likelihood of full recovery from stroke and prevent future strokes from occurring Stroke is the leading cause of adult disability and is in the top five causes of death globally. Warlow's Stroke: Practical Management, 4th Edition takes a problem-oriented approach and addresses the questions posed by a stroke patient in the order they are likely to present in clinical practice, for instance, 'Is it a stroke?', 'What sort of stroke?', 'What caused it?', and 'What can be done about it?'. Beginning with chapters phrased as questions, the book walks the reader through a standard clinical workflow, exploring the practical skills and assessment required at each stage of patient management. Early chapters cover: locating the vascular lesion, identifying the involved arterial territory, the role imaging should play, and the application thereof. Subsequent chapters look at what causes a transient or persistent ischemic event, an intracerebral hemorrhage and a subarachnoid hemorrhage. Unusual causes of ischemic stroke and transient ischemic attack are also covered. The book then presents a practical approach to the management of stroke and transient ischemic attack; offers specific treatments for acute ischemic stroke and aneurysmal subarachnoid hemorrhage; provides ways for professionals to prevent first or recurrent stroke; and more. Final chapters of the book discuss rehabilitation after stroke, how patients and carers can be supported in the short term and long term, prevention of recurrent stroke, and the organization of stroke services. Warlow's Stroke: Practical Management, 4th Edition Follows clinical workflow for stroke analysis Features evidence-based approach throughout Offers practical application aimed at improving patient outcomes Written and edited by internationally renowned experts in the field An essential resource for all practitioners involved in the care of patients who suffer from cerebrovascular disease, but particularly suitable for neurologists, residents, geriatricians, stroke physicians, radiologists and primary care physicians.
Download or read book Moyamoya Disease written by Vicente Vanaclocha and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Moyamoya disease is a rare cerebrovascular disease most prevalent in East Asian countries. Thanks to new diagnostic capabilities, the number of cases discovered, including asymptomatic patients, has been increasing steadily. However, asymptomatic from the clinical point of view does not necessarily mean that there are no subjacent problems. Indeed, many patients harbour cognitive decline long before they exhibit clinical or radiological manifestations. The only effective treatment is surgical revascularization, either direct, indirect, or combined. Many posit that preventive surgical treatment should be considered even in asymptomatic moyamoya patients, particularly in the paediatric age group. This book expands on these ideas and examines the various aspects of this dreadful disease.
Download or read book Stroke Revisited Diagnosis and Treatment of Ischemic Stroke written by Seung-Hoon Lee and published by Springer. This book was released on 2017-09-15 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents state of the art knowledge on stroke management in a unique organizational style. Ischemic stroke is extensively covered, with inclusion of overviews that dynamically describe all relevant diagnostic and therapeutic processes in a time sequence mirroring real practice. The individual components of management and key issues are fully discussed with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to retrieve fundamental information quickly. In addition, the book considers the various causes of stroke and provides detailed guidance on means of secondary prevention. The recent demonstration of the substantial benefit of intra-arterial thrombectomy using stentrievers in patients with acute ischemic stroke represents a great moment in the history of stroke management. As we embark on a new era, there is an urgent need to review and evaluate current modalities for stroke diagnosis and treatment. In tackling this task, this book will be invaluable for physicians, angiographic interventionists, surgeons, and students seeking to acquire up-to-date knowledge on stroke.
Download or read book Pharmacoepigenetics written by Ramón Cacabelos and published by Academic Press. This book was released on 2019-06-04 with total page 986 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacoepigenetics provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine. - Fully examines the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, treatment, current epigenetic drugs and the application of epigenetic procedures in drug development - Features chapter contributions from leading international researchers in academia, clinical settings and the pharmaceutical industry - Instructs researchers, students and clinicians on how to better interpret and employ pharmacoepigenetics in drug development, efficiency and safety - Provides a balanced and objective discussion of the future of pharmacoepigenetics and its crucial role in precision medicine
