Download or read book Motilin written by Zen Itoh and published by Elsevier. This book was released on 2012-12-02 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motilin focuses on the pharmacology and physiology of motilin, with emphasis on its relationship to interdigestive motor activities and species differences between these two parameters. Changes in plasma motilin in relation to some gastrointestinal diseases, including peptic ulcer, cholelithiasis, chronic idiopathic constipation, dumping syndrome, and irritable bowel syndrome, are discussed. This book is comprised of 17 chapters and begins with a historical background on motilin, including its discovery and isolation. The next chapter considers the structure of motilin in pigs and cats and presents evidence for the existence of motilin in other species. The chemical synthesis, radioimmunoassay, and immunoreactivity of motilin are also examined. Subsequent chapters explore the prohormone of human motilin; morphological identification of motilin in the gut; mechanisms of motilin excitation as determined by in situ and in vitro studies; and motilin receptors. This monograph should be of interest to scientists, physiologists, clinical specialists, morphologists, pharmacologists, and biochemists.

Download or read book Neuropeptide Function in the Gastrointestinal Tract written by Edwin E. Daniel and published by CRC Press. This book was released on 2019-08-15 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1991: This book assimilates and evaluates the rapidly accumulating information regarding neuropeptides in the gut, their chemistry; genetic control; processing in enteric nerves; the projections of their nerves; their actions at the tissue, cell, and molecular levels; and their roles in controlling gut motility in health and disease. Neuropeptide Function in the Gastrointestinal Tract is directed to scientists in all disciplines who work with neuropeptides, as well as physiologists interested in the neural and smooth muscle actions of neuropeptides.

Download or read book Handbook of Hormones written by Yoshio Takei and published by Academic Press. This book was released on 2015-08-26 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research collates fundamental information about the structure and function of hormones from basic biology to clinical use. The handbook offers a rapid way to obtain specific facts about the chemical and molecular characteristics of hormones, their receptors and signalling pathways, and the biological activities they regulate. The evolution of hormones and gene families is also covered both in the text and in online ancillaries. Users will find simple and visual ways to learn key molecular information. Chapters and online ancillary resources integrate additional sections, providing a comparative molecular, functional, and evolutionary consideration. Provides the only single resource available with concise, yet informative descriptions of hormones in vertebrates, invertebrates, and plants Presents hormones in groups according to their origin, so that readers can easily understand their inter-relation Includes comparative information on the structures and functions of hormones enabling readers to understand both general and specific actions in and across species Ancillary website hosts additional information, including sequence data, comparative data, figures, and tables

Download or read book Gastrointestinal Hormones written by Viktor Mutt and published by Academic Press. This book was released on 2013-10-22 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Metabolic Disorders, Volume 11: Gastrointestinal Hormones covers the developments in the study of gastrointestinal (GI) hormones. The book discusses the cytochemical techniques in work with GI hormones; the general aspects and problems for the radioimmunoassays of GI hormones in the 80s; and the response of the GI hormone system to the pathological changes. The text also describes the evolutional aspects of GI hormones; the cell membrane receptors for secretagogues on pancreatic acinar cells; and the synthesis of GI hormones using organic chemical or recombinant DNA techniques. Gastrin is reviewed with regard to its forms and fragments in tissues, circulating components during post- and perisecretory processing, cellular origins and distribution, actions and structure-function relations, metabolic disposal, nervous and chemical control for its release, and its role in human pathology. The book further tackles the chemical, anatomical, and biological studies on gastrin-releasing peptides, as well as the physiological actions of gastric inhibitory polypeptide. Discussions about the vasoactive intestinal peptide, incretin, enteroglucagon, neuropeptide Y, peptide HI, galanin, cholecystokinin-58, neuropeptide K, peptide YY, motilin, somatostatin-28, neurotensin, substance P, and opioid peptides are also encompassed. The text concludes by looking into the investigations on the structure and function of the head activator in hydra and in mammals. Molecular biologists, endocrinologists, histochemists, physiologists, and those involved in the research about GI hormones will find the book invaluable.

Download or read book Encyclopedia of Gastroenterology written by and published by Academic Press. This book was released on 2019-11-06 with total page 3420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Gastroenterology, Second Edition provides a comprehensive and concise reference on all aspects of gastroenterology and hepatology, including the organs in the gastrointestinal system, their functions in health and disease, and strategies or procedures to resolve or prevent problems and disease. This concise, up-to-date information includes comprehensive sections on the impact of nutrition, gastrointestinal microbiota, lifestyle, commonly used drugs, and surgical procedures on health and disease. Since the first edition, attention to the roles of nutrition and gastrointestinal microorganisms (microbiota, formerly Microbiota) in health and disease has skyrocketed. In addition, an entirely new section on obesity and diabetes is included. Presents comprehensive coverage of every topic within gastroenterology Offers researchers a one-stop, fully-referenced resource to explore questions Includes teaching tools, multimedia and interactive elements Provides readers with multi-layered content and a media-rich learning resource for both instructors and students Covers hot new topics in GI health and disease, including new sections on stem cells, intestinal bacteria, obesity and intestinal microbiota

Download or read book Physiology of the Gastrointestinal Tract Two Volume Set written by Hamid M. Said and published by Academic Press. This book was released on 2012-07-04 with total page 2250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis, celiac disease, Crohn’s disease, peptic ulcer, stomach ulcer, viral hepatitis, colorectal cancer and liver transplants. The new edition is a highly referenced and useful resource for gastroenterologists, physiologists, internists, professional researchers, and instructors teaching courses for clinical and research students. 2013 Highly Commended BMA Medical Book Award for Internal Medicine Discusses the multiple processes governing gastrointestinal function Each section edited by preeminent scientist in the field Updated, four-color illustrations

Download or read book Physiology of the Gastrointestinal Tract written by Kim E. Barrett and published by Elsevier. This book was released on 2006-05-10 with total page 2098 pages. Available in PDF, EPUB and Kindle. Book excerpt: FROM THE PREFACE: The original purpose of the First Edition of Physiology of the Gastrointestinal Tract to collect in one set of volumes the most current and comprehensive knowledge in our field was also the driving force for the Fourth Edition. The explosion of information at the cellular level, made possible in part by the continued emergence of powerful molecular and cellular techniques, has resulted in a greater degree of revision than that of any other edition. The first section, now titled "Basic Cell Physiology and Growth of the Gl Tract" contains numerous new chapters on topics such as transcriptional regulation, signaling networks in development, apoptosis, and mechanisms in malignancies. Most of the chapters in this section were edited by Juanita L. Merchant. Section II has been renamed "Neural Gastroenterology and Motility" and has been expanded from seven chapters with rather classic titles to more than twenty chapters encompassing not only the movement of the various parts of the digestive tract but also cell physiology, neural regulation, stress, and the regulation of food intake. Almost all of the chapters were recruited and edited by Jackie D. Wood. The third section is entirely new and contains chapters on "Immunology and Inflammation" which were edited by Kim E. Barrett. The fourth section on the "Physiology of Secretion" consists of chapters with familiar titles, but with completely updated information to reflect the advances in our understanding of the cellular processes involved in secretion. The last section on "Digestion and Absorption" contains new chapters on the intestinal barrier, protein sorting and ion channels along with those focusing on the uptake of specific nutrients. These chapters were recruited and edited by Hamid M. Said and Fayez K. Ghishan. · Collected in one set - the most current and comprehensive coverage of gastrointestinal physiology · Information presented in a style that is both readable and understandable · Valuable to the specialized researcher, the clinical gastroenterologist, the teacher, and the student · Features an entirely new section on Immunology and Inflammation · Each section edited by the preeminent scientist in the field

Download or read book Brain gut Peptides and Reproductive Function written by Charles D. Barnes and published by CRC Press. This book was released on 2020-07-24 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elucidates the role of brain-gut peptides in neuroendocrine regulation for understanding how these peptides interact with the reproductive neuroendocrine axis and for developing novel therapeutic agents for fertility or contraceptive therapies.

Download or read book Gastrointestinal Motility in Health and Disease written by H.L. Duthie and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Gastrointestinal Hormones and Pathology of the Digestive System written by Morton Grossman and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery that the same or similar peptides are present in endocrine cells and in neurons is one of the most exciting and provocative recent developments in biology. Suddenly neurophysiologists and endocrinologists have found that they have a great deal to discuss with each other. Substances originally isolated as hypothalamic hormones turn out to be abundantly present in neurons of other parts of the brain and in endocrine cells and neurons of the gut and pancreas. Similarly, substances originally isolated as gut hormones are found not only in gut endocrine cells but also in gut neurons and in brain neurons. It turns out that the group of peptides that we are accustomed to call gastrointestinal hormones are not all confined to the gastrointestinal tract and are not all solely hormones. We are learning that the chemical transmitters of the neurocrine, endocrine, and paracrine systems form a single group of related substances. This volume contains the latest installments in this fascinating story. It tells how these pep tides were isolated and their amino acid sequences determined, how the heterogeneity of most, perhaps all, of these peptides is being revealed as variant forms of them are discovered, how antibodies to these peptides are used as powerful tools to measure their concentrations in body fluids and to localize the cells in which they are synthesized and stored, and, finally, how the role of these substances in normal physiology and in pathological states is being unraveled.

Download or read book Macrolide Antibiotics written by Satoshi Omura and published by Elsevier. This book was released on 2002-07-12 with total page 655 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifungal research and treament.

Download or read book Progress in Medicinal Chemistry written by and published by Elsevier. This book was released on 2009-11-15 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems. Presents the latest research in the field of drug discovery Publishes on a twice yearly basis to bring you the most innovative updates in medicinal chemistry Available as an online resource via ScienceDirect

Download or read book Amino Acids Peptides and Proteins written by R C Sheppard and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Download or read book Gastrointestinal Motility written by C. Roman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the most recent knowledge in the field of gastrointestinal motility in health and disease. The topics addressed include basic as well as clinical data concerning the motor functions of the entire gut: the lower oesophageal sphincter and the gastro-oesophageal reflux; the gastric emptying and the role of the pylorus; the motility of the biliary tract and its disorders; the cyclic motor activity of the gut and intestinal transit; the colonic and ano-rectal motility. There are also impOltant contributions in physiology and pharmacology relating to the neurohumoral regulation of the gut, and the function of digestive smooth muscle. Several papers explore the nature of the linkage between brain and gut. a link which has long been deduced by clinicians but not, until recently, systematically explored by scientists. The individual papers, selected from a large number of submissions, have been subject to 'peer-review' by an inter national committee which includes both cliniCians and basic scientists. Therefore this book should serve as an up to date source of information for researchers concerned with basic sciences as well as for clinicians in gastroenterology, medicine and surgery. C. Roman v This volume is dedicated to the memory of two friends and colleagues: Professor Dr J. HELLEMANS Professor Dr H. MONGES Acknowledgments This was the 9th of this series of symposia held alternatively in Europe and North America, and the first to be held in France.

Download or read book Gastrointestinal Pharmacology written by Beverley Greenwood-Van Meerveld and published by Springer. This book was released on 2017-04-19 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.

Download or read book The Esophagogastric Junction written by Robert Giuli and published by John Libbey Eurotext. This book was released on 1998 with total page 1674 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the 5th in an exceptional series which, in a most uncommon way, constitutes an original encyclopaedia of esophagology. It is devoted to a single subject: the esophagogastric junction. These few centimetres are dissected into 420 questions which call on all the disciplines involved by its physiology, its diverse diseases and their various treatments. 450 answers, provided by the most renowned experts, each one shedding light on one small, but essential, fragment of the subject. The book offers: A succesion of syntheses; A profusion of targeted bibliographical references; An access, now made easy, to highly elaborated knowledge; A precious volume for researchers, specialists, departments heads, general practitioners and students.

Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.