Download or read book Mononitrates written by J.N. Cohn and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nitrates have remarkable clinical effects that have stood the test of time in the management of ischemic heart disease. What is unusual about this class of com pounds is that, after many years of clinical use, we are still exploring new avenues as to the vascular mechanisms of their effect, their applications in treating other clini cal conditions, and the development of products with more favorable pharmacoki netic properties. This volume represents the proceedings of a symposium held June 14-16, 1984, in Montreux. The papers were selected to explore the current state of knowledge re garding the mechanisms of action, pharmacokinetics, and clinical efficacy of ni trates. Particular attention has been given to newer studies utilizing the 5-mononi trate metabolite of isosorbide dinitrate, a drug whose pharmacokinetic properties may make it an important new agent in the treatment of angina and congestive heart failure. One of the benefits of an international meeting of experts sharing their views on an internationally used group of drugs is that differences in concepts and clinical practice become apparent and can be discussed. The Montreux forum made it clear that clinicians in North and South America and Europe have diverging views on how the nitrates should be used.

Download or read book Organic Nitrates written by P. Needleman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.

Download or read book Mononitrates written by Jay N. Cohn and published by Springer. This book was released on 1985 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nitrates III written by P. Lichtlen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacological and clinical research on nitrates continues to be of growing interest in many centers. This is surprising in view of the fact that their favorable effects in angina pectoris were described by Brunton and by Murrell in the Lancet more than 100 years ago. As expected, a host of new information has been collected since the two previous symposia on nitrates held in Stockholm in 1975 and Berlin in 1978. New insights were gained into the pharmacology, pharmacokinetics and pharmacodynamics of nitrates, as well as into their clinical effects in acute and chronic ischemic heart diseases and in severe congestive heart failure. Relatively little progress, however, was observed in research into the basic action of nitrates. Although most investigators agree that intracellular sequestration of calcium is probably the main mechanism by which nitrates lead to the reduction of vascular smooth muscle tone, the exact site of their action still remains undefined. In contrast, dose-dependent differences in venous and arteriolar tone have long been clearly established. Treatment was again in the main stream of discussion. The question of tolerance following long-term administration was discussed in depth and the term "pseudotolerance" was introduced to describe the adaptation of the body's circulatory system to chronic vasodilation. This is especially important in long term prophylactic antiischemic treatment in stable, as well as in unstable angina pectoris (i.e. during increased vasomotor tone - spasm).

Download or read book Emergency Response Guidebook written by U.S. Department of Transportation and published by Simon and Schuster. This book was released on 2013-06-03 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does the identification number 60 indicate a toxic substance or a flammable solid, in the molten state at an elevated temperature? Does the identification number 1035 indicate ethane or butane? What is the difference between natural gas transmission pipelines and natural gas distribution pipelines? If you came upon an overturned truck on the highway that was leaking, would you be able to identify if it was hazardous and know what steps to take? Questions like these and more are answered in the Emergency Response Guidebook. Learn how to identify symbols for and vehicles carrying toxic, flammable, explosive, radioactive, or otherwise harmful substances and how to respond once an incident involving those substances has been identified. Always be prepared in situations that are unfamiliar and dangerous and know how to rectify them. Keeping this guide around at all times will ensure that, if you were to come upon a transportation situation involving hazardous substances or dangerous goods, you will be able to help keep others and yourself out of danger. With color-coded pages for quick and easy reference, this is the official manual used by first responders in the United States and Canada for transportation incidents involving dangerous goods or hazardous materials.

Download or read book Davis s Drug Guide for Rehabilitation Professionals written by Charles D. Ciccone and published by F.A. Davis. This book was released on 2013-03-21 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!

Download or read book Isosorbide Mononitrate written by G. J. Blokdijk and published by . This book was released on 2018-01-29 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Could I have afforded it without Isosorbide Mononitrate prescription drug insurance? Should I be concerned about all the Isosorbide Mononitrate medication I need to take to stay on top of my health problems? How much do I need to really understand about the interactions of my Isosorbide Mononitrate prescription drugs? How to go about it if I want to use a lower dosage of Isosorbide Mononitrate? How will Isosorbide Mononitrate affect the other medications that I'm taking? Always talk to your doctor about Isosorbide Mononitrate, your condition and your treatment. But what exactly to ask your doctor to make sure you are both covering everything you need to know about Isosorbide Mononitrate? 'Isosorbide Mononitrate; A Complete Guide' presents readers with a whole new set of 608 pivotal questions to discuss your situation with your healthcare provider, consider your options, and help you make decisions that are right for you. 'Isosorbide Mononitrate; A Complete Guide' poses questions that Isosorbide Mononitrate medication users didn't even know they needed to ask. With lots of room to note down your doctor's answers and an extensive index, this book is a must-have for anyone who has, or is about to have, Isosorbide Mononitrate prescription medication, and indispensable for healthcare providers who want to make sure they are able to answer every question.

Download or read book Coronary Microvascular Dysfunction written by Filippo Crea and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.

Download or read book Nitrate Therapy Nitrate Tolerance written by Dženana Rezaković and published by S. Karger AG (Switzerland). This book was released on 1993 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Drugs for Heart Disease written by John Hamer and published by Springer. This book was released on 2013-11-11 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the outcome of a cardiologist switching to clinical pharma cology in mid-career and may be seen as representing the interface between the two disciplines. In this second edition I have not tried to be encyclopaedic, but have asked the contributors to give a brief account of current practice, so that it represents the present state of cardiac thera peutics. Although some contributors are from Bart's, I have tried to spread my net widely and produce a general view from the English speaking world. I hope this will be enough to draw the teeth of my colleagues who will react at once to say that 'this is not what we do at Bart's. ' Some chapters, mostly the early ones, are drug orientated and describe the use and properties of individual groups of drugs. Other later chapters are disease orientated and describe the use of various groups of drugs in different conditions, such as angina or hypertension. This necessarily leads to some overlap, but I have not tried to produce a uniformity of view, but have been content with Chairman Mao 'to let a hundred flowers bloom'. I am grateful to my cardiological colleague, Professor A. John Camm for his help and advice on current cardiological practice. To improve the flow of the text I have limited the references to key publications, rather than trying to quote all the papers published on each topic.

Download or read book Cardiology Explained written by Euan A. Ashley and published by Remedica. This book was released on 2004 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most time-consuming tasks in clinical medicine is seeking the opinions of specialist colleagues. There is a pressure not only to make referrals appropriate but also to summarize the case in the language of the specialist. This book explains basic physiologic and pathophysiologic mechanisms of cardiovascular disease in a straightforward manner, gives guidelines as to when referral is appropriate, and, uniquely, explains what the specialist is likely to do. It is ideal for any hospital doctor, generalist, or even senior medical student who may need a cardiology opinion, or for that ma.

Download or read book Handbook of Pharmacokinetic Pharmacodynamic Correlation written by Hartmut Derendorf and published by CRC Press. This book was released on 2019-06-04 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1995: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and time, and pharmacodynamics (PD), the relationship between drug effects and concentration, this handbook examines the relevant relationship between drug effects and time.

Download or read book Dorland s Illustrated Medical Dictionary E Book written by Dorland and published by Elsevier Health Sciences. This book was released on 2011-05-27 with total page 2176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated, this user-friendly reference, trusted for more than a century by healthcare personnel at every professional level, allows you to grasp the meanings of all medical terms in current usage. Understand and correctly use all the latest terminology in today’s ever-evolving medical field with the 32nd Edition of the comprehensive, highly respected Dorlands Illustrated Medical Dictionary! Enhance your understanding of all the current medical terminology in your field by relying on the most comprehensive and highly respected medical dictionary, bringing you more than 120,000 well-defined entries and 1500 clear illustrations. Make sure you’re familiar with the very latest medical terms used today with more than 5,500 new entries drawn from current sources. Complement your understanding of new words and ideas in medicine with 500 new illustrations Get more information in a smaller amount of space as the revised entry format includes related parts of speech.

Download or read book Nitrate Esters Chemistry and Technology written by Jiping Liu and published by Springer. This book was released on 2019-03-06 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea of this book is to present the up-to-date research results on Nitrate Esters as explosive materials. It covers many aspects including the material structures, nitrating agent, chemical synthesis devices, preparation technology, and applications etc. In particular, this work sheds light on the comprehensive utilization and thorough destruction of the used Nitrate Easters which is crucial for preventing repeated pollution. This is a highly informative and instructive book providing insight for the researchers working on nitrating theory, energetic materials and chemical equipments.

Download or read book Index Nominum written by and published by CRC Press. This book was released on 2004 with total page 1939 pages. Available in PDF, EPUB and Kindle. Book excerpt: : 2004 Book News, Inc., Portland, OR (booknews.com).

Download or read book Memorizing Pharmacology A Relaxed Approach written by Tony Guerra and published by Lulu.com. This book was released on 2015-12-31 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a working parent of 4-year-old triplet daughters, I understand time management presents one of the greatest barriers to my pharmacology students' success. Many students feel that cold sense of overwhelm and information overload. This easy-to-read guide organizes pharmacology into manageable, logical steps you can fit in short pockets of time. The proven system helps you memorize medications quickly and form immediate connections. With mnemonics from students and instructors, you'll see how both sides approach learning. After you've finished the 200 Top Drugs in this book, reading pharmacology exam questions will seem like reading plain English. You'll have a new understanding of pharmacology to do better in class, clinical and your board exam. You'll feel the confidence you'd hoped for as a future health professional. For patients and caregivers, this book provides a means to memorize medications to quickly and articulately communicate with your health providers.

Download or read book Electron Capture written by A. Zlatkis and published by Elsevier. This book was released on 1981-01-01 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electron Capture