Download or read book Molecular Studies on the PheP Gene of Escherichia Coli K 12 written by Jing Pi and published by . This book was released on 1991 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Studies on the TyrB Gene of Escherichia Coli K 12 written by Chi Yang and published by . This book was released on 1989 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Molecular Characterization of the SfaA Gene of Escherichia Coli K 12 written by Yun Miao and published by . This book was released on 1993 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies of Mutations in Essential Genes in Escherichia Coli K 12 written by Karen Augur Armstrong and published by . This book was released on 1975 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies on the Genetic System of Escherichia Coli K 12 written by Luigi Luca Cavalli-Sforza and published by . This book was released on 1956 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Characterisation of the PheP Permease of Escherichia Coli K 12 written by Con Dogovski and published by . This book was released on 2004 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular and genetic analysis of purine genes in Escherichia coli K 12 written by Tahir Habib Malik and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Studies of Regulation Mediated by the TyrR Protein of Escherichia Coli K 12 written by Blair Lawley and published by . This book was released on 1994 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetic and Molecular Analysis of the RecR Locus of Escherichia Coli K 12 written by Akeel Abdulla Mahdi and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular and Functional Analysis of the SbcC Gene of Escherichia Coli K12 written by Isam Said Naom and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies on the Molecular Organisation and Permeability of the Outer Membrane of Escherichia Coli K 12 written by Shu-Yun Qi and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular and genetic studies of pyridoxal 5 phosphate biosynthesis in Escherichia coli K 12 written by Hon-Ming Lam and published by . This book was released on 1992 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dynamics of Genetic Adaptation in Escherichia Coli K12 MG1655 written by Margaret Kenyon Applebee and published by . This book was released on 2010 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteria replicate quickly enough that adaptive changes can be observed on a timescale of weeks to months. Laboratory adaptive evolution experiments with bacteria, especially of Escherichia coli, have been used to study population dynamics and evolutionary processes. Recent advances in DNA sequencing now make it possible to identify all of the acquired mutations and interrogate the adaptive process at the molecular level. The first two research studies in this dissertation analyze mutations acquired by E. coli during prolonged growth on glycerol minimal media. In the first study I measured fitness differences between independently-evolved lineages and between mutations acquired by the same gene in different lineages by head-to-head competitions. This allowed small fitness differences to be detected between independently-evolved strains and between mutations to the same genes. This also detected epistatic interactions between several mutations. Overall these results provide the basis for understanding how the mutations individually and cooperatively affect fitness. The second study examines adaptive mutations to glycerol kinase (GlpK), which were acquired by almost all glycerol-adapted lineages. The relative ability of the GlpK mutations to increase fitness was used to identify the enzyme function responsible for improving phenotype, which was found to be sensitivity to the inhibitor fructose-1,6-bisphosphate. However, the GlpK mutants also induce autocatabolite repression which reduces glpK transcription, attenuating the ability of the mutations to increase glycerol metabolism. This likely occurs to prevent methylglyoxal toxicity. Additionally, the GlpK mutations altered growth on several sugars, but it is unclear what mechanism could be involved suggesting it is a novel function. This study demonstrates how adaptive mutations can be studied to identify constraints on expressed phenotype and to identify novel protein interactions. The goal of the third study was to integrate genes for cellulose-degrading enzymes into the E. coli genome, and to use adaptive evolution to select for strains that improve use of the genes that allow growth on cellulose. This was both a metabolic engineering and basic research project, to produce a potentially useful strain and to study the molecular dynamics involved in integrating a novel metabolic function into the existing metabolic and regulatory network.
Download or read book Studies on the Cloned OmpC Gene of Escherichia Coli K 12 written by Gregory Anthony McDonald and published by . This book was released on 1984 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biological Studies on the Rep Gene of Escherichia Coli microform written by Carol A. Gilchrist and published by National Library of Canada. This book was released on 1988 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: My work has involved the sequencing of the Escherichia coli rep gene. This gene codes for the Rep helicase, a ssDNA-dependent ATPase required by some phages ($\Phi$X174, fd, P2) for their replication.
Download or read book Studies on the Expression and Structure of the PurA Gene from Escherichia Coli K 12 written by Steven Alan Wolfe and published by . This book was released on 1990 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biological Studies on the Rep Gene of Escherichia Coli written by Carol A. Gilchrist and published by . This book was released on 1987 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
