Download or read book Molecular Regulation of Germ Cell Number and Fate in the Nematode C Elegans written by Liana B. Lamont and published by . This book was released on 2006 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Germ Cell Development in C elegans written by Tim Schedl and published by Springer Science & Business Media. This book was released on 2012-08-09 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Germ cells in sexually reproducing metazoa, through the germline lineage, are the route by which genetic material and cytoplasmic constituents are passed from one generation to the next in the continuum of life. Chapters in this book review germ cell development in the model organism Caenorhabditis elegans, discussing the biology, the genetics and the molecular mechanisms for various processes, as well as drawing comparisons with other organisms. Processes discussed include specification of germ cell fate, meiosis, gametogenesis, environmental/ physiological controls, epigenetics and translational control, fertilization and the oocyte-to-embryo transition. This book thus provides a comprehensive picture of the germline lineage and the continuum of life for the worm.
Download or read book Germline Stem Cells written by Steven X. Hou and published by Humana Press. This book was released on 2014-10-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this comprehensive and cutting-edge book, leading experts explore the parameters that define germline stem cells and the mechanisms that regulate the cell behavior in order to better isolate, characterize and maintain them. The volume begins by providing protocols for germline stem cell identification and regulation in model organisms, and concludes with detailed chapters covering current techniques involving in vitro culture and the applications of the cells.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetic and Molecular Analysis of GLP 1 a Gene Required for Cell Cell Interactions in the Nematode Caenorhabditis Elegans written by Judith Ann Austin and published by . This book was released on 1989 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cell Fate in the C Elegans Germline is Regulated by the CPEB Protein FOG 1 written by Suk-Won Jin and published by . This book was released on 2000 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nematode Models of Development and Disease written by and published by Academic Press. This book was released on 2021-05-13 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nematode Models of Development and Disease, Volume 144 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters surrounding Transgenerational inheritance, Oscillatory expression and function, Concepts and functions of small RNA pathways in C. elegans, Exploring the nuclear lamina in health and pathology using C. elegans, Cellular Plasticity, Morphogenesis, Tubulogenesis, Organogenesis forces, Programmed cell fusion in development and homeostasis, One template, two outcomes: how does the sex-shared nervous system generate sex-specific behaviors?, Metabolic Cellular Coordination of Gene-Environment Interactions, and much more. Other chapters cover Chemical and physical cues and micro-evolution in early embryogenesis, Innate immunity, Sex and Death, Dendrites maturation, axonal growth and extracellular glycoproteins, Autophagocytosis, Spermatogenesis, and the developmental and physiological roles of phagocytosis in Caenorhabditis elegans. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology
Download or read book Genetic Control of Cell Fate Specification in Caenorhabditis Elegans Germline written by SRIVALLI MAMILLAPALLI and published by . This book was released on 2015 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt: The precise regulation of germ cell fates (sperm or oocyte) lies at the heart of reproduction and fertility. The nematode Caenorhabditis elegans hermaphrodites produce a discrete number of sperm during larval development and then switch to produce oocyte during adulthood. A number of positive (e.g., fbf genes) and negative (e.g., gld-3) regulators are important for this switch. Here, we found that aberrant activation of MPK-1 (an ERK homolog) by removal of both fbf-1 and lip-1 partially inhibits sperm-oocyte switch, resulting in Mog (masculinization of germline) sterility. The fbf-1 gene encodes a conserved PUF (Pumilio and FBF) RNA-binding protein and the lip-1 gene encodes an MPK-1/ERK phosphatase. Notably, inhibition of MPK-1/ERK signaling by either genetic mutation or chemical inhibition reprograms the germ cell fate and thus helps in regaining the fertility. We also found that fbf-1; lip-1 Mog sterility was enhanced by the depletion of G2/M cell cycle regulators, including CYB-3/Cyclin B, CDK-1/CDK1, and CDC-25.1/CDC25. Markedly, cdc-25.1 mRNA is a direct target of FBF-1. These results suggest that FBF-1 and LIP-1 may promote sperm-oocyte switch by activating MPK-1/ERK signaling and G2/M cell cycle progression.
Download or read book Molecular and Functional Studies of Lag 2 a Gene Required for Cell cell Interactions During Development of the Nematode C Elegans written by Xiaoben Gao and published by . This book was released on 1996 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Caenorhabditis Elegans written by and published by Academic Press. This book was released on 2011-11-23 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated edition of the classic Methods in Cell Biology volume 48, this book emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of C. elegans for years to come. - Diverse, up-to-date techniques covered will be useful to the broadening community of C. elegans researchers for years to come - Chapters written by leaders in the field - Tried and true methods deliver busy researchers a one-stop compendium of essential protocols
Download or read book The Nematode Caenorhabditis Elegans written by William Barry Wood and published by . This book was released on 1988 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book C Elegans FOG 1 CPEB and FOG 3 Tob Work Together to Control the Oogenesis Program written by and published by . This book was released on 2015 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Germ cell sex determination is an ancient cell fate decision, but the molecular regulation of this fundamental decision is poorly understood. In the C. elegans germline, FOG-1 and FOG-3 are the terminal regulators of sperm fate. Here I explore sex determination on a genome wide scale in the C. elegans germline. First, I report on a new dataset of spermatogenic, oogenic, and gender neutral mRNAs in the germline. Second, I incorporate the sperm, oocyte, and maternal transcriptome datasets into this new dataset to characterize these transcripts into oogenic and spermatogenic mRNA programs. Third, I identify 81 FOG-1 associated mRNAs and 722 FOG-3 associated mRNAs. 76 of the FOG-1 associated mRNAs are also FOG-3 associated mRNAs and most of these mRNAs are oogenic program mRNAs. FOG-1 and FOG-3 also co-localize in the germline and co-immunoprecipitate suggesting that FOG-1 and FOG-3 work together. I propose a model in which FOG-1 and FOG-3 are in a complex repressing oogenic mRNAs to specify sperm fate.
Download or read book The Nematode Caenorhabditis Elegans written by William Barry Wood and published by Firefly Books. This book was released on 1988 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1965 Sydney Brenner chose the free-living nematode Caenorhabditis elegans as a promising model system for a concerted genetic, ultrastructural, and behavioral attack on the development and function of a simple nervous system. Since then, with the help of a growing number of investigators, knowledge about the biology of "the worm" has accumulated at a steadily accelerating pace to the extent that C. elegans is now probably the most completely understood metazoan in terms of anatomy, genetics, development, and behavior. The past few years have seen the completion of two major long-term projects that provide new insights into C. elegans development and lay important groundwork for future investigation: completion of the cell lineages of both sexes, from zygote to adult, and description of the complete anatomy at the level of electron microscope resolution, providing a complete "wiring diagram" of cell contacts in the animal. Recent years have also brought the first successes in molecularly cloning genes of developmental interest defined only by mutation, using transposon tagging as a generally applicable method for identification of the desired DNA sequences. Reintroduction of cloned DNA sequences into the genome has recently been accomplished. A physical map of the genome has been assembled with a combination of cosmid and YAC genes. This "Book of the Worm" serves as a reference source for C. elegans investigators as well as an introductory monograph for other biologists.
Download or read book Meiosis and Gametogenesis written by and published by Academic Press. This book was released on 1997-11-24 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: In spite of the fact that the process of meiosis is fundamental to inheritance, surprisingly little is understood about how it actually occurs. There has recently been a flurry of research activity in this area and this volume summarizes the advances coming from this work. All authors are recognized and respected research scientists at the forefront of research in meiosis. Of particular interest is the emphasis in this volume on meiosis in the context of gametogenesis in higher eukaryotic organisms, backed up by chapters on meiotic mechanisms in other model organisms. The focus is on modern molecular and cytological techniques and how these have elucidated fundamental mechanisms of meiosis. Authors provide easy access to the literature for those who want to pursue topics in greater depth, but reviews are comprehensive so that this book may become a standard reference.Key Features* Comprehensive reviews that, taken together, provide up-to-date coverage of a rapidly moving field* Features new and unpublished information* Integrates research in diverse organisms to present an overview of common threads in mechanisms of meiosis* Includes thoughtful consideration of areas for future investigation
Download or read book C Elegans II written by Donald L. Riddle and published by Firefly Books. This book was released on 1997 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR
Download or read book Advances in Developmental Biology written by Paul Wassarman and published by Elsevier Science. This book was released on 1997-11-04 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 5 of Advances in Developmental Biology and Biochemistry consists of seven chapters that review specific aspects of development in several different organisms, including sea urchins, flies, worms, frogs, and mice. In Chapter 1, Wassarman and Therrier provide a detailed analysis of RAS1-mediated photoreceptor development in Drosophila as determined by genetic and biochemical approaches. Much of the information in this area has come from studies of the role of RAS1 in the Sevenless (SEV) signal transduction pathway that specifies the R7 photoreceptor cell fate. In Chapter 2, Westlund, Berry, and Schedl describe the regulation of germline proliferation in the nematode, C. elegans. In large part, the authors discuss components of signaling pathways, including glp-1 and other members of the Notch protein family that are crucial for a germ cell's decision of whether to remain mitotic or to enter meiotic prophase. In Chapter 3, Richards details the current status of the ecdysone regulatory cascade in Drosophila. In a comprehensive presentation, he describes ecdysone-regulated chromosomal puffs, their corresponding genes, and the receptors and transcription factors involved in the ecdysone regulatory cascade. In Chapter 4, Tam, Quinlan, and Trainor describe the patterning of progenitor tissues for the cranial region of the mouse embryo during gastrulation and early organogenesis. In particular, the authors review the sequence of developmental processes that delineate major tissue domains and the finer segmental organization of the progenitor tissues for the formation of craniofacial structures. In Chapter 5, Bodmer and his colleagues detail the genetic basis of heart development in Drosophila. Here, the authors discuss various gene functions that are required for the initial specification and later differentiation of the heart and compare molecular mechanisms that lead to heart formation in Drosophila with those that may be involved in heart formation in vertebrates. In Chapter 6, Tata Discusses hormonal signaling and amphibian metamorphosis. Following a review of amphibian metamorphosis, the author describes thyroid hormone receptors, the genes encoding them, and their target genes, as well as how their activities are coordinated by signaling molecules. Finally, in Chapter 7, Kaldis and colleagues discuss the functions of creatine kinase (CK) isozymes in spermatozoa from a variety of mammalian and nonmammalian species.
Download or read book The Evolution of Developmental Mechanisms written by Michael Akam and published by . This book was released on 1994 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
