Download or read book Molecular Physiology and Metabolism of the Nervous System written by Gary A. Rosenberg and published by Oxford University Press. This book was released on 2012-04-01 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular basis for the physiology of the brain has advanced enormously in the past twenty years with an influx of new information gleaned through technological developments in neuroimaging and molecular discoveries. Molecular Physiology and Metabolism of the Nervous System, authored by Gary A. Rosenberg, an authority on the physiology of brain fluids and metabolism, combines the classic physiology that dates back to the beginning of the nineteenth century with the advances in molecular sciences, providing a strong framework for understanding the diseases that are commonly treated by neurologists. Molecular Physiology and Metabolism of the Nervous System focuses on the current neuropathology and implications of cerebrospinal fluid diseases and diseases of the blood-brain barrier: how the two affect stroke, infection, brain tumors, and increased intracranial pressure. The book discusses the effects of blood flow in stroke and dementia, the disruption of the blood-brain barrier in neuroinflammation, and the dysfunction due to brain edema and increased intracranial pressure. Molecular Physiology and Metabolism of the Nervous System is necessary reading for neurologists, neuroscientists, and residents in neurology, neurosurgery, and psychiatry, giving them a strong grounding in physiology and metabolism that will aid them in diagnosis and treatment.
Download or read book Metabolism of the Nervous System written by Derek Richter and published by Elsevier. This book was released on 2013-10-22 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism of the Nervous System contains the proceedings of the 2nd International Neurochemical Symposium, held at Aarhus, Denmark, in July 1956. The book discusses the molecular structure and morphology of the adult nervous tissue; the chemical composition and cytochemical localization of adult nervous tissue; and the permeability and blood-brain barrier. The text also describes topics on electrolytes and nervous conduction; the metabolism of isolated nerve and ganglion; and the metabolism of the brain in vivo. The metabolism of brain tissue preparations in vitro; energy metabolism and coenzymes in relation to the nervous system; and lipid and fatty acid metabolism are also considered. The book further tackles nucleic acid metabolism; protein and amino acid metabolism; and cholinergic and non-cholinergic transmission. The text also discusses other pharmacologically active compounds related to the adult nervous tissue.
Download or read book Molecular and Cellular Physiology of Neurons written by Gordon L. Fain and published by Harvard University Press. This book was released on 2015-01-05 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cellular Physiology of Neurons: Second Edition is a comprehensive, up-to-date introduction to essential concepts of cellular neuroscience. Emphasizing experimental approaches and recent discoveries, it provides an in-depth look at the structure and function of nerve cells, from protein receptors and synapses to the biochemical processes that drive the mammalian nervous system. Starting with the basics of electrical current flow across cell membranes, Gordon Fain covers voltage gating and receptor activation in the context of channel diversity, excitatory and inhibitory synaptic transmission, neuromodulation, and sensory transduction. Emphasizing long-term processes of synaptic potentiation and depression involved in memory, consciousness, and attention, he demonstrates how cells produce neural signals and regulate signal flow to enhance or impede cell-to-cell communication. Fain also addresses the relation of molecular and cellular mechanisms to evolving theories of neurological disease and addiction. Enhanced by more than two hundred illustrations, Molecular and Cellular Physiology of Neurons: Second Edition is intended for anyone who seeks to understand the fundamentals of nerve cell function, including undergraduate and graduate students in neuroscience, students of bioengineering and cognitive science, and practicing neuroscientists who want to deepen their knowledge of recent discoveries in molecular and cellular neurophysiology.
Download or read book Glial Physiology and Pathophysiology written by Alexei Verkhratsky and published by John Wiley & Sons. This book was released on 2013-01-31 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverae includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role og glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides
Download or read book The Neuron written by Irwin B. Levitan and published by Oxford University Press, USA. This book was released on 2015 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.
Download or read book Neural Regulation of Metabolism written by Qi Wu and published by Springer. This book was released on 2018-11-02 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summarizes the humoral mechanisms by which critical adipocyte-derived hormones and lipoprotein lipase regulate lipid and glucose metabolism, and examines the role of the hypothalamus-sympathetic nerve, a critical nerve pathway from CNS to peripheral nervous system (PNS), in the regulation of metabolism in multiple tissues/organs. Furthermore, the book discusses the functions of adipose tissue in energy metabolism. Lastly, it explores dietary interventions to treat neural diseases and some of the emerging technologies used to study the neural regulation of metabolism. Presenting cutting-edge developments in the neural regulation of metabolism, the book is a valuable reference resource for graduate students and researchers in the field of neuroscience and metabolism.
Download or read book Fuel Homeostasis and the Nervous System written by Mladen Vranic and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has a dual purpose, to review in depth the control of fuel homeostasis in the brain and the role of the nervous system in the control of fuel deposition in the body. From the methodological point of view the emphasis is on the application of advanced technologies to assess fuel transport and brain metabolism, the role of peptides in the neuroendocrine system and the response of the brain to hypoglycemia. These technologies include positron emmission tomography, nuclear magnetic resonance, immunocytochemistry, molecular biology, autoradiography. To study fuel homeostasis in the body advanced tracer methods that include modelling are set out. From the pathophysiological point of view the emphasis is on abnormalities in stress, brain metabolism in diabetes, eating and degenerative disorders. This book contains contributions from endocrinologists, physiologists, neurologists, psychoneuroendocrinOlogists, biophysicists, biochemists and experts in nutrition. This authorship represents a unique diversity of researchers who, for the first time, cover comprehensively the interaction between the nervous system and fuel homeostasis, both in health and disease. We hope this book will be an important source of information for both researchers and practicing clinicians. Mladen Vranic Suad Efendic Charles Hollenberg v ACKNOWLEDGEMENTS The Symposium from which this volume arose (University of Toronto, June 27-28, 1990) was the first Toronto-Stockholm symposium on Perspectives in Diabetes Research. These Symposia are organized triennially by the Banting and Best Diabetes Centre, University of Toronto and the Department of Endocrinology, Karolinska Institute, Stockholm.
Download or read book Neural Metabolism in Vivo written by Springer and published by . This book was released on 2012-03-09 with total page 1192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Physiology and Pathology of Chloride Transporters and Channels in the Nervous System written by Francisco J. Alvarez-Leefmans and published by Academic Press. This book was released on 2009 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. This book is about how chloride ions are regulated and how they cross the plasma membrane of neurons. It spans from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases.
Download or read book Basic Neurochemistry written by Scott Brady and published by Academic Press. This book was released on 2011-11-02 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475
Download or read book Principles of Neurochemistry written by Bijo Mathew and published by Springer Nature. This book was released on 2020-09-21 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides medical professionals and researchers with a comprehensive overview of fundamental concepts and recent advances in neurochemistry, and offers new perspectives for all those involved with research in related disciplines. As drug discovery for neurodegenerative diseases is one of the largest subspecialties in the field of medicine, the book addresses topics that transcend the borders between disciplines, and presents a wealth of investigations into and discussions on critical questions relevant to the entire field of CNS drug research. It summarizes the available data on the fundamentals of neurotransmitters, treatment of and advanced care for neurodegenerative diseases; and outlines current and future research directions in this field. Combining both conventional and innovative approaches to the topic, the book offers a valuable guide for readers working in medicinal chemistry, the life sciences and allied fields.
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Caffeine for the Sustainment of Mental Task Performance written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-07 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
Download or read book Alcohol and the Nervous System written by Edith V. Sullivan and published by Elsevier. This book was released on 2014-10-08 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function
Download or read book Fundamentals of Anaesthesia written by Colin Pinnock and published by Cambridge University Press. This book was released on 2002-12 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Download or read book Molecular Exercise Physiology written by Adam Sharples and published by Taylor & Francis. This book was released on 2022-05-11 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised and expanded, the second edition of Molecular Exercise Physiology offers a student-friendly introduction. It introduces a history documenting the emergence of molecular biology techniques to investigate exercise physiology, the methodology used, exercise genetics and epigenetics, and the molecular mechanisms that lead to adaptation after different types of exercise, with explicit links to outcomes in sport performance, nutrition, physical activity and clinical exercise. Structured around key topics in sport and exercise science and featuring contributions from pioneering scientists, such as Nobel Prize winners, this edition includes new chapters based on cutting-edge research in epigenetics and muscle memory, satellite cells, exercise in cancer, at altitude, and in hot and cold climates. Chapters include learning objectives, structured guides to further reading, review questions, overviews of work by key researchers and box discussions from important pioneers in the field, making it a complete resource for any molecular exercise physiology course. The book includes cell and molecular biology laboratory methods for dissertation and research projects in molecular exercise physiology and muscle physiology. This book is essential reading for upper-level undergraduate or postgraduate courses in cellular and molecular exercise physiology and muscle physiology. It is a valuable resource for any student with an advanced interest in exercise physiology in both sport performance and clinical settings.
