Download or read book Molecular Pathology of Neoplastic Gastrointestinal Diseases written by Antonia R. Sepulveda and published by Springer Science & Business Media. This book was released on 2013-01-28 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Pathology of Neoplastic Gastrointestinal Diseases reviews the molecular aspects that characterize the spectrum of neoplastic conditions that affect the gastrointestinal tract, providing the reader with current up-to-date knowledge. For each disease entity chapters provide reviews on: the molecular basis of the individual disease molecular testing approaches currently available or in development for diagnosis or for gene target characterization for selective targeted therapies recommended guidelines for clinical application of molecular tests are included whenever available molecular testing for hereditary predisposition or disease risk animal models and cell culture models of disease

Download or read book Neoplastic Gastrointestinal Pathology written by Laura W. Lamps and published by Springer Publishing Company. This book was released on 2015-07-15 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: " Approximately 20 million gastrointestinal tract biopsies are performed each year in the United States. While many of these are straightforward, some are histologically subtle or involve a complex differential diagnosis. This concise visual guide to the full range of neoplastic gastrointestinal specimens provides the practicing pathologist or trainee with a clear analysis and diagnosis of both common and potentially misleading variants of disease. The authors cover the full tubular GI tract with over 600 high-quality images and a concise description of the key features of each entity: definitions and terminology, gross and morphologic features, differential diagnoses, useful ancillary tests, staging and grading parameters, and special clinical considerations. Images depict differential diagnosis features, frequently seen variants that can potentially lead to misclassification or misdiagnosis, and correlated molecular and immunologic techniques. "

Download or read book Molecular Pathology of Neoplastic Gastrointestinal Diseases written by Antonia R. Sepulveda and published by Springer. This book was released on 2013-01-27 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Pathology of Neoplastic Gastrointestinal Diseases reviews the molecular aspects that characterize the spectrum of neoplastic conditions that affect the gastrointestinal tract, providing the reader with current up-to-date knowledge. For each disease entity chapters provide reviews on: the molecular basis of the individual disease molecular testing approaches currently available or in development for diagnosis or for gene target characterization for selective targeted therapies recommended guidelines for clinical application of molecular tests are included whenever available molecular testing for hereditary predisposition or disease risk animal models and cell culture models of disease

Download or read book Molecular Pathology of Gastroenterological Cancer written by Eiichi Tahara and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty years have passed since I became a professor in the First Department of Pathology, Hiroshima University School of Medicine. It is my great pleas ure that Molecular Pathology o[ Gastroenterological Cancer-Application to Clinical Practice has been published by Springer-Verlag Tokyo to commemo rate the 20th anniversary of my professorship. Seeing the academic achievements of our department during these 20 years, I am confident that we could establish a department of oncology to research the pathogenesis of human cancer through systemic application of a variety of molecular techniques. We have demonstrated that the develop me nt and progression of esophageal, gastric, and colon cancer require mul tiple alterations affecting DNA mismatch repair genes, oncogenes, and tumorsuppressor genes, and that common and uncommon genetic changes exist for esophageal, gastric, and colorectal carcinomas. In addition to these genetic changes, the majority of gastrointestinal cancers express telomerase activity, with overexpression of telomerase RNA, indicating a powerful addi tional tool for early detection of gastrointestinal cancer. By transferring these basic observations to the clinic, we now are able to make accurate cancer diagnoses, thus determing the grade of malignancy and patient prognosis. We also can identify patients at high risk for developing cancer and create new therapeutic approaches. In fact, we have routinely implemented a new molecular diagnosis strategy at the Hiroshima City Medi cal Association Clinical Laboratory since August 1993.

Download or read book Precision Molecular Pathology of Neoplastic Pediatric Diseases written by Larissa V. Furtado and published by Springer. This book was released on 2018-08-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, state-of-the art review of pediatric oncology. The text covers relevant concepts in molecular biology and addresses technical principles, applications, challenges, and integration of current and emerging genomic and molecular methods in the diagnosis and personalized management of childhood cancers. The text also discusses a wide array of pediatric neoplasms in the context of molecular pathology in a concise and understandable manner, with focus on their molecular pathogenesis, clinicopathological features, classification, molecular diagnosis, and approaches to personalized care. Written by experts in the field, Precision Molecular Pathology of Neoplastic Pediatric Diseases serves as a valuable resource for pathologists, pediatric oncologists, trainees and researchers with an interest in pediatric and molecular pathology.

Download or read book Gastrointestinal Pathology written by Geraint T. Williams and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been many advances in the field of gastrointestinal pa thology which are of considerable clinical significance during the 13 years since the last publication of a volume of Current Topics in Pathology devoted to this subject. Many have arisen from the app lication of new techniques of histochemistry, immunocytochemi stry, quantitative morphometry and molecular and cell biology to gastrointestinal diseases, but some, notably the recognition of the association of Campylobaeter pylori with the commonest type of chronic gastritis, have been achieved using such long established 'routine' histological procedures that one wonders how their signifi cance had escaped recognition for so long. The topics covered in this volume have been selected because they present advances of relevance to the diagnostic clinical pathologist. However, they re present the personal selection of the editor, and are in no way exhaustive. Many other examples of progress in our understanding of the pathophysiology of gastrointestinal diseases have been omit ted, either because of the confines of space or because they have been well reviewed recently in other publications. Most of the workload of the practising gastrointestinal patholo gist involves the diagnosis and assessment either of inflammation or of neoplasia in the alimentary tract, and this is reflected in the topics presented in this book.

Download or read book Gastrointestinal Pathology Classification Diagnosis Emerging Entities An Issue of Surgical Pathology Clinics E Book written by Jason L. Hornick and published by Elsevier Health Sciences. This book was released on 2013-09-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Overall, this book is an excellent update on many important entities..." Reviewed by: Kay Lawson, on behalf of ACP News; Date: Summer 2014. The gastrointestinal tract may be affected by a diverse spectrum of inflammatory and neoplastic disorders, many of which pose problems for practicing surgical pathologists on a daily basis. Pathologists' understanding of these diseases continues to evolve rapidly. The topics in this issue of Surgical Pathology Clinics address a wide range of neoplasms and present ancillary techniques that play an increasingly important role in diagnostic pathology and include prognostic and predictive markers that have become a routine part of gastrointestinal pathology practice. These expert reviews provide surgical pathologists with critical practical updates on many of these challenging areas, with an emphasis on differential diagnosis and diagnostic pitfalls. Some topics include: Lymphomas of the gastrointestinal tract; Mesenchymal tumors of the gastrointestinal tract other than GIST; Barrett's esophagus: evolving concepts in diagnosis and neoplastic progression; Immunohistochemistry in neoplastic gastrointestinal pathology; HER2 testing in adenocarcinomas of the upper gastrointestinal tract; Pediatric inflammatory gastrointestinal pathology; IgG4-related disorders of the gastrointestinal tract. The reader will be interested in cross referencing the first volume on GI pathology presented in this series; its popularity with surgical pathologists has led to this second volume, which covers different topics in GI pathology. Jason Hornick of Brigham and Women's provides his expertise to lead this issue.

Download or read book Pathology and Clinical Relevance of Neoplastic Precursor Lesions of the Gastrointestinal Tract Liver and Pancreaticobiliary System written by Robert D. Odze and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to recent advances in endoscopy and radiology, there is increased recognition of the prevalence and biological characteristics of neoplastic precursor lesions in the GI tract, liver, biliary tract, and pancreas. As a result, there have been major recent developments in the pathologic classification, diagnosis, molecular pathogenesis, natural history and treatment of these lesions. In addition, there are controversial issues with regard to the value of endoscopic screening and surveillance. A close clinician-pathologist interaction is essential in the management of preneoplastic lesions. In this issue the pathology, biological properties, pathogenesis, natural history, and current treatment recommendations of the major preneoplastic and dysplastic precursor lesions of the GI tract, liver, biliary tract and pancreas are reviewed in detail. Wherever possible, accent is given to controversial diagnostic and management-related issues. Each subject matter is written by experts in the field, all of whom have had research experience in their respective areas.

Download or read book Gastrointestinal and Liver Pathology E Book written by Christine A. Iacobuzio-Donahue and published by Elsevier Health Sciences. This book was released on 2011-06-06 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal and Liver Pathology, a title in the Foundations in Diagnostic Pathology series, provides all the most essential information on the pathological entities encountered in practice in an easy-to-use format. Drs. Christine A. Iacobuzio-Donahue and Elizabeth Montgomery examine the full scope of neoplastic and non-neoplastic disorders of the gastrointestinal tract--, including disorders of the tubular gastrointestinal tract, pancreatobiliary tree, and liver—from clinical features and ancillary studies to differential diagnoses and prognostic and therapeutic considerations. The consistent, practical format with a wealth of illustrations, boxes, and tables make this title ideal for quick reference for both novices and experienced pathologists. Get the full range of coverage on neoplastic and non-neoplastic gastrointestinal/liver conditions in a consistent, user-friendly format. Catch all the nuances of how pathological entities present through over 850 full-color illustrations. Reference key information quickly and easily thanks to at-a-glance boxes and tables throughout the text. Stay current with the latest in molecular diagnostic techniques through a new chapter on this increasingly important topic. Find information on lymphoid neoplasms of the GI tract more easily with coverage consolidated into a new, focused chapter. Easily identify newly described entities highlighted in updated images and references. Enhance your visual understanding from 100 new clinical and photomicroscopic images. Gain increased at-a-glance reference thanks to more fact sheets and pathologic features boxes.

Download or read book Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2017-11-09 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Download or read book Tumors of the Esophagus and Stomach written by Robert D. Odze and published by . This book was released on 2019-02 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Essential Concepts in Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2019-11-23 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Download or read book WHO Classification of Tumours of the Digestive System written by F. T. Bosman and published by International Agency for Research on Cancer. This book was released on 2010-10-15 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The WHO Classification of Tumours of the Digestive System presented in this book reflects the views of a Working Group that convened for an Editorial and Consensus Conference at the International Agency for Research on Cancer (IARC), Lyon, December 10-12, 2009"--P. [5].

Download or read book Atlas of Gastrointestinal Pathology A Pattern Based Approach to Neoplastic Biopsies written by Christina Arnold and published by Lippincott Williams & Wilkins. This book was released on 2018-12-11 with total page 2105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Closely mirroring the daily sign-out process, Atlas of Gastrointestinal Pathology: A Pattern Based Approach to Neoplastic Biopsies is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical chart and locating hidden clues in the slides. Useful as a daily “scope-side guide,” it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report.

Download or read book Gastrointestinal Pathology written by Gregory Y. Lauwers and published by John Wiley & Sons. This book was released on 2021-04-22 with total page 837 pages. Available in PDF, EPUB and Kindle. Book excerpt: An illustrated guide to best practices when performing and assessing biopsies for GI conditions of all kinds Accurate diagnosis of GI conditions necessarily entails both the careful taking of biopsies and the informed analysis of tissue material. With that being so, gastroenterologists and GI pathologists alike must have a solid understanding of the techniques, handling requirements, and diagnostic characteristics involved if they are to collaborate effectively. Gastrointestinal Pathology has been designed to provide a clinically focussed and richly illustrated guide to real-world scenarios faced by practicing GI specialists, offering step-by-step instruction and professional advice on the correct diagnosis of all major GI conditions. This essential new book includes: Full-color illustrations throughout Complete details of biopsy samples required to diagnose specific conditions Reviews of differential diagnoses Clinical management clues based on pathologic findings Featuring information to improve the practice of all gastroenterologists and GI pathologists, Gastrointestinal Pathology is a practical and every-day resource for the precise diagnosis of a wide range of GI conditions.

Download or read book Liver Pathology written by Linda D. Ferrell, MD and published by Demos Medical Publishing. This book was released on 2011-03-28 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book provides detailed insight into a wealth of expert experience in liver pathology, with an in-depth review of the expertÌs analysis and diagnostic process supported by high-quality color photomicrographs and discussion of the diagnostic principles involved in evaluating these lesions. The diagnostic problems and cases selected show the wide range of specimens seen in liver pathology and address the difficult issues in diagnosis encountered in these lesions. Chapters and cases are authored by many of the leading experts and educators in liver pathology today. Liver Pathology will be essential reading for every pathologist who evaluates liver pathology specimens. In addition it will be a valuable resource for pathology residents and fellows. All Consultant Pathology Titles Provide: Actual consultation cases and expert analysis Expert analysis provides a detailed discussion of the reasoning behind the diagnosis of each case Comprehensive coverage of challenging diagnoses The cases are richly illustrated with high-quality photomicrographs

Download or read book Non neoplastic Pathology of the Gastrointestinal Tract written by Roger Feakins and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Prior to the development of the first fibre-optic endoscopes in the 1960's, gastroenterology, in common with other traditional medical specialties, relied on biochemical and radiological techniques in order to investigate the gastrointestinal tract. Histological confirmation of a disease process usually required the presence of a surgeon, was invasive, and carried inherent risks. Because of a rapid improvement in technology, we are now able to sample the entire gastrointestinal tract from the mouth and anus through to the ileal / jejunal junction"--