Download or read book Molecular Mechanisms of Spondyloarthropathies written by Carlos López-Larrea and published by Springer Science & Business Media. This book was released on 2009-12-03 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now over ten years since we edited the first edition of HLA-B27 in the Development of Spondyloarthropathies (SpA). It is obvious that over this period an enormous amount of information concerning SpA and HLA-B27 has accumulated, and this has been reflected in the knowledge of molecular mechanism of the spondyloarthropathies. Discussion for such a book took initial form at the outstanding 4th Gent Symposium on SpA in October 2006, but was not formally commissioned by Landes Bioscience until early 2007. Molecular Mechanisms of Spondyloarthropathies aims to synthesize this growing knowledge and present all the current studies concerning the basic research of SpA. Over the last decade, enormous progress has been made in the understanding of the molecular and cellular processes that lead to disease pathology. Recognition of the pathways involved in the pathogenic mechanisms of disease and the potential to target specific immune effector functions have opened the door to a wide range of innovative treatment opportunities for the SpA. Thus, we believe that the understanding of the specific molecular mechanisms involved would help to design highly specific drugs in the future. The contributors are among the best in their field and reflect the state of the art of research and current opinion of rheumatologists and immunologists.
Download or read book Musculoskeletal Diseases 2021 2024 written by Juerg Hodler and published by Springer Nature. This book was released on 2021 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on imaging of the musculoskeletal diseases. Over the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors are all internationally renowned experts in their field. They are also excellent teachers, and provide didactically outstanding chapters. The book is disease-oriented and covers all relevant imaging modalities, with particular emphasis on magnetic resonance imaging. Important aspects of pediatric imaging are also included. IDKD books are completely re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their specialty.
Download or read book Axial Spondyloarthritis written by Stefan Siebert and published by Oxford University Press. This book was released on 2016 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical pocketbook for the nonspecialist practitioner, Axial Spondyloarthritis is the essential guide to the commonest inflammatory arthritis affecting the spine. Focusing on the practical implications of developments in classification, diagnosis, and treatment, this easily accessible text fully covers the broader spectrum of this condition.
Download or read book Adverse Effects of Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 2012-04-26 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
Download or read book Activity Diet and Social Practice written by Sarah Schrader and published by Springer. This book was released on 2018-12-05 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Day-to-day activities are important in the development of social identities, the establishment of social standing, and the communal understanding of societal rules. This perspective is broadly referred to as practice theory and relates to the power of an overarching social structure and the individual actors that exist within it. Practice theory has made an important contribution to anthropological and archaeological research as these fields are particularly interested in daily life and the importance of these actions. This volume argues that practice theory can also be used in a bioarchaeological context through the examination of human skeletal remains and the archaeological context in which they were excavated. Bioarchaeology offers a unique perspective on these day-to-day experiences—skeletal tissue is constantly undergoing a process of change and, as a living biological system, it can adapt to external forces. Furthermore, bioarchaeological studies are multi-scalar and can examine individuals, groups, or entire populations. Using osteological indicators of activity patterns (entheseal changes, osteoarthritis) and dietary isotopes (carbon, nitrogen) as examples, this book addresses patterns of everyday life in the ancient past. Physical activities and food consumption are actions that are carried out on a daily basis. While bioarchaeology does not have the ability to recreate specific day-to-day activities, we can assess broad trends in everyday life. The volume illustrates these points using examples from the Ancient Nile Valley. Through the examination of over 800 Egyptian and Nubian individuals from five different archaeological sites, the research addresses patterns of everyday life as they relate to social inequality, agency, and practice. Beyond osteological indicators of activity and dietary patterns, this book also discusses additional methods that can be pursed to draw attention to daily life. Lastly, this book also highlights the applicability of and potential contribution that practice theory can make to this area of research.
Download or read book Spondyloarthropathies An Issue of Rheumatic Disease Clinics written by Juergen Braun and published by Elsevier Health Sciences. This book was released on 2012-08-28 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by Drs. Juergen Braun and Joachim Sieper, this issue of Rheumatic Disease Clinics comprehensively reviews the state of the art of spondyloarthritis (SpA) diagnosis, prognosis, pathogenesis and genetic insights, and treatment. The worldwide burden of SpA now exceeds that of rheumatoid arthritis. General topics covered include inflammatory back pain, pathophysiology, imaging techniques, and therapeutic strategies.
Download or read book Molecular Pathogenic Mechanisms of Spondyloarthropathies written by Luis R. Espinoza and published by . This book was released on 1995 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summarizes recent events in the understanding of molecular pathogenic mechanisms in spondyloarthropathies, such as better characterization of clinical syndromes, the association with HLA-B27 mediated genetic factors, and the role of microorganisms, and covers the clinical and therapeutic aspects of this group of diseases as well. Topics include HLA antigens and seronegative spondyloarthropathies, experimental animal models of the diseases, humoral and cellular immune studies, the role of cytokines, and other genetic factors. Includes bandw photos. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases written by Mitesh Kumar Dwivedi and published by Springer Nature. This book was released on 2022-08-10 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book in the two volume set provides comprehensive coverage on how microbial pathogens can subvert our immune system into responding against self and resulting into autoimmune diseases. In particular, the book covers the different aspects of linking gut microbiota dysbiosis with autoimmune mechanisms involved in disease development to identify future effective approaches based on the gut microbiota for preventing these autoimmune diseases. Contributions in the book focuses on the role of microbiota/probiotics and their distinct mechanisms exerted in management of autoimmune liver, skin, thyroid, rheumatic and myopathic diseases. This could help in better understanding to design therapeutic strategies that can be deployed to prevent these autoimmune diseases. The book has an interdisciplinary appeal and scholars with an interest immunology, medical microbiology and nutritional sciences will value its contribution. Overall, the book gives a new dimensions and insight in the aspects of microbial role in autoimmune disease pathogenesis and therapeutic aspects.
Download or read book Clinical and Molecular Advances in Ankylosing Spondylitis written by Jacome Bruges-Armas and published by BoD – Books on Demand. This book was released on 2012-02-22 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first section of the book entitled Clinical and Molecular Advances in Ankylosing Spondylitis is a review of the clinical manifestations of Ankylosing Spondylitis (AS) and Spondyloarthritis (SpA). The book includes chapters on Bone Mineral Density measurements, two chapters on the temporomandibular joints, axial fractures, clinical manifestations, diagnosis, and treatment. Molecular genetics and immune response are analyzed in the second section of the book; information on HLA-B*27, other MHC genes and the immune response of AS patients to bacteria is reviewed and updated. Two chapters are dedicated to recent information on non-MHC genes in AS susceptibility, and to new data on disease pathways generated from gene expression studies on peripheral blood.
Download or read book Musculoskeletal Medicine in Primary Care written by Dr Solomon Abrahams and published by Xlibris Corporation. This book was released on 2014-02-18 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to help MSK Physicians, Physiotherapists, Osteopaths, G.Ps and other respected colleagues in the examination, diagnosis and management of Common MSK pathologies presenting in primary care. Chapters are sectioned according to the anatomical area of the body. Each chapter consists of Basic Anatomy, Subjective (including differential diagnosis and red flags) and Objective examination, Observation and Physical examination, special tests (and their reliability), Pathologies, key points and flow charts for triaging. Where possible, we have used evidence based research to suppliment the practice based experience within the book. Some special chapters are dedicated to common pathologies seen in the elderly and children/ adolescents. Other chapters include Joint injections in primary care, Medicines that conflict with MSK diagnosis/management, common blood results and their meaning and common connective tissue disorders. Where possible, we have supplemented chapters with Scans, X rays, Pictures and flow charts to help explain the simplicity of each pathology. The flow charts at the end of each primary chapter is to help triage pathologies.
Download or read book Oxford Textbook of Rheumatology written by Philip Conaghan and published by Oxford University Press. This book was released on 2013-10 with total page 1553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.
Download or read book Imaging of Arthritis and Metabolic Bone Disease E Book written by Barbara N. W. Weissman and published by Elsevier Health Sciences. This book was released on 2009-05-09 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get state-of-the-art coverage of the full range of imaging techniques available to assist in the diagnosis and therapeutic management of rheumatic diseases. Written by acknowledged experts in musculoskeletal imaging, this richly illustrated, full-color text presents the latest diagnostic and disease monitoring modalities - MRI, CT, ultrasonography, nuclear medicine, DXA — as well as interventional procedures. You'll find comprehensive coverage of specific rheumatic conditions, including osteoarticular and extraarticular findings. This superb new publication puts you at the forefront of imaging in arthritis and metabolic bone disease — a must have reference for the clinician and imaging specialist. Includes all imaging modalities relevant to rheumatic disease, and applications and contraindications of each, for balanced coverage. Incorporates a user-friendly, consistent full-color format for quick and easy reference. Provides osteoarticular and extra-articular features and findings to show how imaging benefits diagnosis and management of complex rheumatologic conditions. Creates a one-stop shop with comprehensive coverage of imaging for all rheumatic conditions, including metabolic conditions and pediatric disorders. Presents interventional techniques—injections, arthrography, radiofrequency ablation—to create the perfect diagnostic and interventional clinical tool.
Download or read book Alternative Antigen Processing and Presentation in Immune Disorders written by Iñaki Alvarez and published by Frontiers Media SA. This book was released on 2022-10-19 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Rheumatology Handbook written by Margaret Callan and published by World Scientific. This book was released on 2012 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Rheumatology Handbook is a unique resource for medical students and non-specialist doctors. It represents a collaborative effort between specialists from major teaching hospitals within the UK and Ireland, with each chapter being edited by a different consultant rheumatologist with the relevant subspecialty interest. Written clearly and concisely and well illustrated, the book provides readers with the basic scientific information that they require to understand current concepts about the pathogenesis of rheumatological disease, and draws on recent research studies to give up-to-date information about investigation and treatment. It covers the full range of rheumatological conditions, from local degenerative problems to systemic immune-mediated disease. It includes a useful section on soft-tissue disorders and a practical guide to performing soft-tissue and joint injections; at the other end of the clinical spectrum, the rationale for and efficacy of novel treatments targeted at individual components of the immune response are well explained.
Download or read book Molecular Mimicry Infection Inducing Autoimmune Disease written by Michael B. A. Oldstone and published by Springer Science & Business Media. This book was released on 2006-01-09 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: (Text will follow)
Download or read book Genetic Studies on Spondyloarthritis from Disease Predictors to Therapeutic Targets written by Fabiana Paladini and published by Frontiers Media SA. This book was released on 2022-11-01 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mayo Clinic Internal Medicine Board Review Questions and Answers written by Robert D. Ficalora and published by Oxford University Press, USA. This book was released on 2013-08-15 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Companion volume to: Mayo Clinic internal medicine board review. 10th ed. c2013.
