Download or read book Cellular and Molecular Mechanisms of Breast Cancer Metastasis to the Brain written by Christoph B. Wyss and published by . This book was released on 2016 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemoresistance and Metastasis in Breast Cancer Molecular Mechanisms and Novel Clinical Strategies written by Qifeng Yang and published by Frontiers Media SA. This book was released on 2022-03-18 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Kowalski Henri pianist composer written by and published by . This book was released on 19?? with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Material in the Australian performing arts programs and ephemera (PROMPT) collection consists of programs and related items for Australian performing arts organisations, Australian artists performing overseas, professional productions performed in Australia (including those featuring overseas performers) and overseas performances of Australian plays, music, etc.
Download or read book Understanding Molecular Mechanisms of Breast Cancer Metastasis Using Genetically engineered Mice written by Leah Marie Cook and published by . This book was released on 2011 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Mechanisms of Cancer written by Georg F. Weber and published by Springer Science & Business Media. This book was released on 2007-09-12 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes molecular processes whose deregulation is important in the formation of tumors. The material is developed from basic cell signaling pathways to their roles in the clinical manifestation of specific cancers. Topics covered include molecular events intrinsic to tumor cells (leading to growth deregulation, extended lifespan, and the ability to invade surrounding tissue), protective mechanisms that prevent transformation (including DNA repair and epigenetic regulation), tumor-host interactions (with the endocrine system, the immune system, and blood vessel formation), and the underlying molecular defects of individual cancers.
Download or read book Tumor Microenvironment Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression written by Antonella Zannetti and published by Frontiers Media SA. This book was released on 2021-09-30 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advancements in Metastatic Breast Cancer Predictive and Prognostic Biomarkers and Molecular Mechanisms written by Masakazu Toi and published by Frontiers Media SA. This book was released on 2022-09-27 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Mechanisms of Breast Cancer Metastasis written by Yusuf Tutar and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer (BC) is one of the most frequently occurring diseases with high morbidity and mortality rates in the world today. BC cells live under stress with altered pathway signaling, chromosome and microsatellite instability, aneuploidy, hypoxia, low pH, and low nutrient conditions. In order to survive and reproduce in these stressful environments, BC cells rapidly undergo adaptive mutations, rearrange their chromosomes, and repress tumor suppressor genes while inducing oncogene activities that cause the natural selection of cancer cells and result in heterogeneous cancer cells in the tumor environment. Unfortunately, these genetic alterations result in aggressive BC cells that can not only proliferate aggressively but also migrate and invade the other tissues in the body to form secondary tumors. In this review, molecular mechanisms of metastasis of BC subtypes are discussed.
Download or read book Molecular Mechanisms of Breast Cancer Metastasis written by Thomas Morgan Bodenstine and published by . This book was released on 2010 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Mechanisms of Circulating Tumor Cell Adhesion in Breast Cancer Metastasis written by Venktesh S. Shirure and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bone Metastasis and Molecular Mechanisms written by Gurmit Singh and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients with advanced breast or prostate cancers usually develop bone metastases. The principal complications resulting from metastatic bone disease are pain, spinal cord compression, pathologic fractures and bone marrow suppression. Improving the management of bone metastases is crucial to quality of life for patients with breast and prostate cancer. Advances in understanding of the molecular mechanisms underlying the pathophysiology of bone metastasis are driving the development of new therapeutic strategies.
Download or read book A Study of Breast Cancer Heterogeneity and Molecular Mechanisms of Metastasis written by Daniel Patrick Hollern and published by . This book was released on 2015 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Transcriptional Networks Controlling Breast Cancer Metastasis written by and published by . This book was released on 2015 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Breast Cancer Metastasis and Drug Resistance written by Aamir Ahmad and published by Springer Nature. This book was released on 2019-08-27 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
Download or read book Breast Cancer Metastasis and Drug Resistance written by Aamir Ahmad and published by Springer Science & Business Media. This book was released on 2012-11-08 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume comprehensively covers recent prrogress in breast cancer research. In an effort to successfully treat breast cancer, it is imperative to a) fully understand the disease with all its heterogeneity, b) understand the factors that influence the metastasis of breast cancer to distant organs making it lethal and c) understand the underlying processes that lead to the phenomenon of drug-resistance making the disease particularly incurable. The book explores all of these issues, including the phenomenon of epithelial-mesenchymal-transition, cancer stem cells as well as microRNAs in an attempt to better understand the disease in connection to its heterogeneity/metastasis/drug-resistance as well as to propose novel signaling pathways for therapeutic intervention. The profiling of tumors to molecularly classify breast cancers is also investigated so that customized targeted therapies can be developed.
Download or read book Cancer Metastasis Molecular and Cellular Mechanisms and Clinical Intervention written by Wen G. Jiang and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the molecular and cellular aspects of cancer metastasis, and discusses the clinical aspect of micro- and macro-metastases, which result in the death of the majority of patients with cancer. The current edition attempts to examine the current status of the basic scientific and clinical research in the area, and is a very useful reference for clinicians, oncologists, and biologists. It is intended for undergraduates as well as postgraduates in the area of medicine, oncology, and cancer biology.
Download or read book Molecular Mechanisms of Metastasis Suppression in Human Breast Cancer written by and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our preliminary data indicated the presence of a breast carcinoma metastasis suppressor genes on human chromosome 11. The goal was to identify and begin characterizing the gene(s) responsible. Two approaches were proposed - (1) introduction of smaller pieces of chromosome 11 into cells with assessment of metastatic potential; and (2) identification of differentially expressed mRNA in metastasis suppressed cells. Progress using Approach #1 was not successful. Approach #2 was successful. We identified three novel cDNAs using differential display which were more highly expressed in the metastasis-suppressed neo11/435 hybrids. Moreover, one of those candidates, BRMS1, significantly suppressed metastasis in two human breast carcinoma cell lines when transfected and constitutively expressed. BRMS1 1 maps to 11q13, a site commonly involved in late-stage breast carcinoma. The mechanism of action appears to be novel, but was not determined during the funding period. In summary, we accomplished the stated ultimate objective for DAMD-17-96-1-6152. Results generated from DAMD-17- 96-1-6152 were used to successfully compete for funding from the National Cancer Institute to follow-up on these exciting findings.
