Download or read book Molecular Interventions and Local Drug Delivery written by Elazer R. Edelman and published by Bailliere Tindall Limited. This book was released on 1995 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances continue to be made in elucidating the cellular and molecular mechanisms of cardiovascular diseases. Recent technical innovations - in molecular therapies and local drug delivery - now permit clinicians to exploit information on pathophysiology in order to treat these conditions more effectively. In this significant new work, Elazer Edelman and Robert Levy bring together a team of authorities in the field, integrating basic and clinical research data with state-of-the-art engineering and technology, to give the cardiovascular physician a clear, readable and up-to-the-minute resource of invaluable information, in the first systematic and comprehensive review of this area.

Download or read book Field Trials of Health Interventions written by Peter G. Smith and published by . This book was released on 2015 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an open access title available under the terms of a CC BY-NC 4.0 International licence. It is free to read at Oxford Scholarship Online and offered as a free PDF download from OUP and selected open access locations. Before new interventions are released into disease control programmes, it is essential that they are carefully evaluated in field trials'. These may be complex and expensive undertakings, requiring the follow-up of hundreds, or thousands, of individuals, often for long periods. Descriptions of the detailed procedures and methods used in the trials that have been conducted have rarely been published. A consequence of this, individuals planning such trials have few guidelines available and little access to knowledge accumulated previously, other than their own. In this manual, practical issues in trial design and conduct are discussed fully and in sufficient detail, that Field Trials of Health Interventions may be used as a toolbox' by field investigators. It has been compiled by an international group of over 30 authors with direct experience in the design, conduct, and analysis of field trials in low and middle income countries and is based on their accumulated knowledge and experience. Available as an open access book via Oxford Medicine Online, this new edition is a comprehensive revision, incorporating the new developments that have taken place in recent years with respect to trials, including seven new chapters on subjects ranging from trial governance, and preliminary studies to pilot testing.

Download or read book Local Drug Delivery for Coronary Artery Disease written by Edoardo Camenzind and published by CRC Press. This book was released on 2005-06-14 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Restenosis remains the Achilles heel of Percutaneous Coronary Interventions. Numerous pharmacological agents have been tested in order to reduce acute thrombosis and the hyperproliferative cellular response, and drug eluting stents-using the stent as a platform for local drug delivery-are now considered a significant breakthrough in interventional cardiology. Pioneers in the field, the editors of Local Drug Delivery for Coronary Artery Disease have assembled an excellent team of contributors who offer their experience with threatened vessel closure and restenosis, acute thrombosis, hyperproliferative cellular response, stents and local drug delivery. They share their expertise on all aspects of the field, including a discussion of results from preclinical and clinical studies, and they examine alternative methods of molecular delivery to the vessel wall. With coverage of the most current methods and applications, as well as a host of photographs illustrating their implementation, this book will serve as an excellent reference for cardiologists, pharmacologists, cardiac surgeons, and trainees.

Download or read book Current Pharmaceutical Design written by and published by . This book was released on 1997-12 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Endoluminal Stenting written by Ulrich Sigwart and published by Bailliere Tindall Limited. This book was released on 1996-01-01 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents the latest in stent technology, theory and clinical practice. Topics include history and experimental data, rheological factors, and clinical application.

Download or read book Local Drug Delivery for Coronary Artery Disease written by Edoardo Camenzind and published by CRC Press. This book was released on 2005-06-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Restenosis remains the Achilles heel of Percutaneous Coronary Interventions. Numerous pharmacological agents have been tested in order to reduce acute thrombosis and the hyperproliferative cellular response, and drug eluting stents-using the stent as a platform for local drug delivery-are now considered a significant breakthrough in interventional cardiology. Pioneers in the field, the editors of Local Drug Delivery for Coronary Artery Disease have assembled an excellent team of contributors who offer their experience with threatened vessel closure and restenosis, acute thrombosis, hyperproliferative cellular response, stents and local drug delivery. They share their expertise on all aspects of the field, including a discussion of results from preclinical and clinical studies, and they examine alternative methods of molecular delivery to the vessel wall. With coverage of the most current methods and applications, as well as a host of photographs illustrating their implementation, this book will serve as an excellent reference for cardiologists, pharmacologists, cardiac surgeons, and trainees.

Download or read book Drug Delivery Systems written by Stroeve Pieter and published by World Scientific. This book was released on 2017-11-27 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the alarming increase in cancer diagnoses and genetic illnesses, traditional drug agents and their delivery media need to be re-evaluated to address a quickly evolving field. With newer smart materials for the controlled release of macromolecules, peptides, genetic material, etc. further complications arise, such as material performance, synthesis, functionalization and targeting, biological identity, and biocompatibility. The book provides a comprehensive overview of the recent developments on "smart" targeting and drug delivery systems with a variety of carriers like nanoparticles, membranes, and hydrogels. It contains detailed descriptions on the recent trends in this field in the ongoing battle with catastrophic diseases like cancer. This field of research has been in its infancy and continues to face growth, and with it, further challenges and difficulties along the way toward maturity, which are accurately introduced in this book. Contents: Drug Delivery Systems: Possibilities and Challenges (Ryan Spitler, Saeid Zanganeh, Tahereh Jafari, Nasser Khakpash, Mohsen Erfanzadeh, Jim Q Ho, and Nastaran Sakhaie)Nanoparticles in Circulation: Blood Stability (Saeid Zanganeh, Tahereh Jafari, Nasser Khakpash, Mohsen Erfanzadeh, and Jim Q Ho)How do Nanoparticles (NPs) Pass Barriers? (Saeid Zanganeh, Ryan Spitler, Najme Javdani, and Jim Q Ho)Gated Porous Materials for Biomedical Application (Félix Sancenón, Erick Yu, Elena Aznar, M Dolores Marcos, and Ramón Martínez-Máñez)Controlled Release from Iron Oxide Nanoparticles (Masoud Rahman)The Reverse of Controlled Release: Controlled Sequestration of Species and Biotoxins into Nanoparticles (NPs) (Jenifer Gómez-Pastora, Eugenio Bringas, María Lázaro-Díez, José Ramos-Vivas, and Inmaculada Ortiz)Membranes for Controlled Release (Vida Araban, Neda Aslankoohi, and Mohammad Raoufi)Controlled Released from Hydrogel (Hossein Riahinezhad, Vida Araban, and Mohammad Raoufi)Nano Delivery Systems (Sophie Laurent, Afsaneh Lahooti, Saeed Shanehsazzadeh, and Robert N Muller)Legal Framework for Protection of Pharmaceutical Trade Marks in Europe and USA (Mohammad Hossein Erfanmanesh, and Shirin Sharifzadeh)Future Perspective on the Smart Delivery of Biomolecules (Erick Yu, Félix Sancenón, Elena Aznar, Ramón Martínez-Máñez, María Dolores Marcos, Mohammad J Hajipour, Morteza Mahmoudi, and Pieter Stroeve) Readership: Nanotechnologists; biomedical engineers; chemical engineers; materials scientists; biotechnology researchers; chemists; biological scientists; cell physiologists; medical scientists; gene therapists. Keywords: Drug Delivery Systems;Nanoparticles;Biomaterials;TargetingReview: Key Features: Comprehensive overview on "smart" targeting and drug delivery systemsUnderstanding of the biological identity of nanoparticles for drug delivery applicationsDetailed information on the legal framework for protection of pharmaceutical trade mark in Europe and the United States

Download or read book Textbook of Interventional Cardiovascular Pharmacology written by Nicolas Kipshidze and published by CRC Press. This book was released on 2007-06-01 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: While all interventional cardiologists have access to pharmacopeial texts and databases and are aware of the growing number of pharmacological agents in the armamentarium, questions arise as to the ideal agent or combination of agents in differing patient situations. This superb text offers the reader coverage of all the major pharmacological t

Download or read book The Annals of Pharmacotherapy written by and published by . This book was released on 1996-07 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Local Drug Delivery for Coronary Artery Disease written by Edoardo Camenzind and published by CRC Press. This book was released on 2005-06-14 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pioneers in the field, the editors have assembled an excellent team of contributors with extensive experience of threatened vessel closure and restenosis, acute thrombosis, hyperproliferative cellular response, stents and local drug delivery. Comprehensive and up-to-date, this reference provides fully up-to-date information on currently available methods of drug delivery, as well as illustrations of drug delivery methods with seventy-five color and seventy-five black and white photos throughout the book. With this impressive presentation of the most up-to-date methods and applications, as well as a range of photographs illustrating their implementation, this guide is an excellent resource for cardiologists, pharmacologists, cardiac surgeons, and trainees.

Download or read book Polymeric Drug Delivery Systems written by Glen S. Kwon and published by CRC Press. This book was released on 2005-04-12 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.

Download or read book Viral Drug Delivery Systems written by Ranjita Shegokar and published by Springer Nature. This book was released on 2023-04-10 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The disability-adjusted life year (DALY) is a generic measure of health effect that can be used in cost-effectiveness analysis as an alternative to the quality-adjusted life year (QALY). Infectious diseases are one of the major to cause significant losses of DALY and QALY. Human infectious diseases are disorders that are triggered by the micro-organisms such as bacteria, fungi, viruses, or parasites. The majority of such diseases are contagious and create a public health menace. There are several reasons why infectious diseases are deadly diseases, and one of the primary reasons is the drug resistance developed over time. Drug resistance-associated mutations are linked to increasing drug efflux, modifications of the drugs, or their targets. Every year, new drugs are being approved by FDA to treat infectious diseases. Nonetheless, the infectious diseases will undoubtedly persist as permanent and main threats to humanity for now and in the future, primarily due to increased longevity that almost always comes at a cost of impaired immunity. A total of four books are covered under the series of Infectious drug diseases. - Malarial drug delivery systems - Tubercular drug delivery systems - Viral drug delivery systems - Infectious disease drug delivery systems The third volume of series is focused on viral drug delivery systems. Typically, virus attaches to the cells (referred as host cell) and releases its DNA or RNA inside the cell. In second stage, virus’s genetic material takes control of the cell and forces it to replicate the virus leading to onset of disease symptoms. DNA class of viruses include Herpes, Papilloma and Adeno viruses. RNA class of viruses include retroviruses, such as HIV immunodeficiency virus and SARS COV – 2 / Corona virus. This book addresses recent developments in viral drug delivery systems. It covers many different aspects of viral infections, ways to treat them using modern drug delivery systems like nano particulate carriers. The choice of viral delivery systems mainly depends upon the type of virus, duration of life cycle, presence of drug resistance, cellular and mucosal interaction of virus, accordingly gene or non-gene drug delivery systems are selected. Besides that, this book also reports global dynamics of viral diseases, future predictions of infection rate, current treatment options, details of drug carriers like nanoemulsions, polymeric nanoparticles, role of biofunctionalization, and phyto-molecules in treatment of viral infections particularly herpes, Covid-19, Ebola, HIV/AIDS, influenza and viral hepatitis. Audiences from a broad range of groups, from researchers, academicians, and public health bodies to regulatory experts, can benefit from the compiled information to learn more about patient needs and current research advances in the field of viral drug delivery research.

Download or read book Clinical Interventional Oncology E Book written by Stephen T Kee and published by Elsevier Health Sciences. This book was released on 2013-09-26 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adhere to best practices and achieve best outcomes with Clinical Interventional Oncology! Loosely structured around the concept of a "tumor board," this groundbreaking oncology reference delivers a comprehensive arsenal of information on the techniques and treatment protocols surrounding chemoembolizations, tumor ablations, minimally invasive tumor biopsies, and other interventional oncologic procedures. Ideal for all members of the cancer care team, it provides the "how to" guidance you need on the clinical, evidence-based application of each interventional procedure. Offer your patients the best care. Evidence-based findings and practical tips equip you with the knowledge you need to recommend and implement the most effective cancer treatment options with your patients. Master all image-guided interventional oncologic procedures currently in practice for the interventional treatment of tumors and lesions in liver, lung, renal, pancreatic, brain, neck, colorectal, skin, prostate, bone, and soft tissue cancers. Broaden your understanding and refine your skills with comprehensive coverage of stents, venous and arterial ports, and interventional procedures for palliative care. Quickly and easily find the information you need. A templated, easy-to-reference format organized by organ system includes anatomy, biology, imaging principles, and procedures integrated throughout each chapter. Experience clinical oncology scenarios with vivid clarity through a full-color design complete with an abundance of high-quality anatomic and multimodality images.

Download or read book Comprehensive Biotechnology written by and published by Newnes. This book was released on 2011-08-26 with total page 5304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Comprehensive Biotechnology, Six Volume Set continues the tradition of the first inclusive work on this dynamic field with up-to-date and essential entries on the principles and practice of biotechnology. The integration of the latest relevant science and industry practice with fundamental biotechnology concepts is presented with entries from internationally recognized world leaders in their given fields. With two volumes covering basic fundamentals, and four volumes of applications, from environmental biotechnology and safety to medical biotechnology and healthcare, this work serves the needs of newcomers as well as established experts combining the latest relevant science and industry practice in a manageable format. It is a multi-authored work, written by experts and vetted by a prestigious advisory board and group of volume editors who are biotechnology innovators and educators with international influence. All six volumes are published at the same time, not as a series; this is not a conventional encyclopedia but a symbiotic integration of brief articles on established topics and longer chapters on new emerging areas. Hyperlinks provide sources of extensive additional related information; material authored and edited by world-renown experts in all aspects of the broad multidisciplinary field of biotechnology Scope and nature of the work are vetted by a prestigious International Advisory Board including three Nobel laureates Each article carries a glossary and a professional summary of the authors indicating their appropriate credentials An extensive index for the entire publication gives a complete list of the many topics treated in the increasingly expanding field

Download or read book Advanced Nanomaterials for Biological Nutraceutical and Medicinal Applications written by Sreeraj Gopi and published by CRC Press. This book was released on 2024-07-26 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume discusses a selection of nanomaterials that can be employed for advanced biological, nutraceutical, and medicinal applications. It discusses diverse nanomaterials and their classifications, their advanced therapeutic properties, using biosensors in detecting biological threat agents, bionanomaterials for human health, the medicinal applications of nanomaterials, clinical toxicities of nanomaterials and their use in remediation. The book also includes a chapter that provides a helpful comparison of market analysis between biological and synthetic nanomaterials. The volume concludes with an insightful perspective on possible future applications of nanomaterials as nutraceutical, biological, and medicinal agents.

Download or read book Brain Cancer Therapy and Surgical Interventions written by Andrew V. Yang and published by Nova Publishers. This book was released on 2006 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are two types of brain tumours: primary brain tumours that originate in the brain and metastatic (secondary) brain tumours that originate from cancer cells that have migrated from other parts of the body. Primary brain cancer rarely spreads beyond the central nervous system, and death results from uncontrolled tumour growth within the limited space of the skull. Metastatic brain cancer indicates advanced disease and has a poor prognosis. Primary brain tumours can be cancerous or non-cancerous. Both types take up space in the brain and may cause serious symptoms (eg: vision or hearing loss) and complications (eg: stroke). All cancerous brain tumours are life threatening (malignant) because they have an aggressive and invasive nature. A non-cancerous primary brain tumour is life threatening when it compromises vital structures (eg: an artery). In the United States, the annual incidence of brain cancer generally is 15-20 cases per 100,000 people. Brain cancer is the leading cause of cancer-related death in patients younger than 35. This new book brings together the leading research in this dynamic area of research.

Download or read book Delivery of Therapeutics for Biogerontological Interventions written by Wing-Fu Lai and published by Academic Press. This book was released on 2019-07-02 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivery of Therapeutics for Biogerontological Interventions: From Concepts to Experimental Design provides tactics on how to facilitate planning and research in interventive biogerontology. The book helps create clearer directions for the translation of existing advances in delivery technologies, from lab to practice. It is ideal as a starting point for scientists, clinicians and those interested in the field of biogerontology, biomedicine or nanotechnology, comprehensively discussing how to translate bench works to practicable tactics that retard the aging process. Using support from recent advances reported in literature, this title takes advantage of delivery technologies to develop biogerontological interventions, from concept to experimental design. Provides the first comprehensive reference to guide researchers through the process of intervention development, from concepts, to practicable interventions Covers the information needed to exploit the use of delivery technologies in intervention biogerontology Presents complete coverage of advances in the field, all of which are supported by full color photographs, figures and references