Download or read book Molecular Genetics of Mycobacteria written by Graham F. Hatfull and published by John Wiley & Sons. This book was released on 2020-08-06 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive collection of perspectives by experts in mycobacterial molecular biology Mycobacterium tuberculosis causes one in four avoidable deaths in the developing world and kills more adults than malaria, AIDS, and all tropical diseases combined. Tuberculosis was named a global health emergency by the World Health Organization, a distinction no other disease has received. Although the study of mycobacterial genetics has expanded dramatically, with new investigations into mycobacterial growth, replication, metabolism, physiology, drug susceptibility, and virulence, most of the problems in tuberculosis control that existed in 2000 remain today. Advances in our understanding of mycobacterial genetics have been reflected in exciting recent developments. New diagnostic approaches can identify drug resistance within a few hours, promising new drugs are progressing through the pipeline and into the clinic, and a range of newly developed vaccines are being evaluated. It is an exciting time as the fruits of 30 years of intensive genetic investigation are finally beginning to emerge. Written by leading experts in the field, Molecular Genetics of Mycobacteria, Second Edition, Discusses key areas of current research in mycobacterial genetics Explains the genetics of the physiology, metabolism, and drug sensitivities of M. tuberculosis Presents genetic approaches for manipulating M. tuberculosis This book is an invaluable resource for anyone interested in the molecular genetics and molecular biology of mycobacteria.
Download or read book Molecular Genetics of Bacteria written by Larry Snyder and published by Wiley-Blackwell. This book was released on 2003 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: This advanced level textbook offers an in-depth look at molecular biology and biochemistry. The breadth and diversity of bacterial genetics are explored in discussions of microbial systems beyond the much-studied E Coli.
Download or read book Molecular Genetics of Bacteria written by Jeremy W. Dale and published by John Wiley & Sons. This book was released on 2004-03-10 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting the basic concepts and most exciting developments, this textbook provides an introduction to the molecular genetics of bacteria in a form suitable for the needs of students studying microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences.
Download or read book Snyder and Champness Molecular Genetics of Bacteria written by Tina M. Henkin and published by John Wiley & Sons. This book was released on 2020-10-27 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: The single most comprehensive and authoritative textbook on bacterial molecular genetics Snyder & Champness Molecular Genetics of Bacteria is a new edition of a classic text, updated to address the massive advances in the field of bacterial molecular genetics and retitled as homage to the founding authors. In an era experiencing an avalanche of new genetic sequence information, this updated edition presents important experiments and advanced material relevant to current applications of molecular genetics, including conclusions from and applications of genomics; the relationships among recombination, replication, and repair and the importance of organizing sequences in DNA; the mechanisms of regulation of gene expression; the newest advances in bacterial cell biology; and the coordination of cellular processes during the bacterial cell cycle. The topics are integrated throughout with biochemical, genomic, and structural information, allowing readers to gain a deeper understanding of modern bacterial molecular genetics and its relationship to other fields of modern biology. Although the text is centered on the most-studied bacteria, Escherichia coli and Bacillus subtilis, many examples are drawn from other bacteria of experimental, medical, ecological, and biotechnological importance. The book's many useful features include Text boxes to help students make connections to relevant topics related to other organisms, including humans A summary of main points at the end of each chapter Questions for discussion and independent thought A list of suggested readings for background and further investigation in each chapter Fully illustrated with detailed diagrams and photos in full color A glossary of terms highlighted in the text While intended as an undergraduate or beginning graduate textbook, Molecular Genetics of Bacteria is an invaluable reference for anyone working in the fields of microbiology, genetics, biochemistry, bioengineering, medicine, molecular biology, and biotechnology. "This is a marvelous textbook that is completely up-to-date and comprehensive, but not overwhelming. The clear prose and excellent figures make it ideal for use in teaching bacterial molecular genetics." —Caroline Harwood, University of Washington
Download or read book Mycobacterium written by Tanya Parish and published by Taylor & Francis. This book was released on 2005 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of people die each year from tuberculosis and millions more are infected. The emergence of drug-resistant forms of Mycobacteriumcombined with the paucity of new drugs makes the study of the molecular biology of this organism especially urgent. In this book expert researchers critically review the current and most recent advances in this vitally important subject. The focus is on the topical and most relevant aspects of mycobacterial molecular biology and the book aims to give readers an insight into the current understanding of the subject and the future direction of research. Chapters include sections on future trends, web resources and useful reference sections. Among the topics covered are DNA replication, cell division, regulatory systems, protein export, drug resistance, vaccine technology, and much, much more. Essential reading for scientists and researchers working on mycobacteria and a recommended text for all microbiology laboratories.
Download or read book Mycobacteria written by C. Ratledge and published by Wiley-Blackwell. This book was released on 1999-11-08 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tuberculosis continues to kills more people than any other single infective agent. The resurgence of the disease in many countries has produced a heightened awareness of the threat posed by mycobacterial infections. At the same time, there has been an explosion of knowledge of the fundamental properties of mycobacteria, most notably the determination of the complete genome sequence of Mycobacterium tuberculosis. This book provides an up-to-date account of these developments in the molecular biology and immunology of mycobacteria, coupled with allied advances of a more applied nature, such as the use of molecular techniques for diagnosis and epidemiological investigations. With chapters contributed from an international team of experts, it will not only be an essential reference text for the expanding mycobacterial research community, but also will find a prominent place on the shelves of clinicians, infectious disease and public health specialists, diagnostic laboratories, postgraduate students and indeed anyone concerned with the management and investigation of outbreaks of tuberculosis. Comprehensively covers recent advances in the molecular biology of the mycobacteria. First book to be published on this subject since the publishing of the complete genome for the tubercle bacillus (M. tuberculosis). Coincides with a worldwide resurgence of tuberculosis.
Download or read book Molecular Genetics of Bacteria written by J. W. Dale and published by . This book was released on 1996 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Mycobacteria written by Johnjoe McFadden and published by Academic Press. This book was released on 1990 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on a meeting held at the University of Surrey in September 1989, this book details progress in search since the first reports of cloning of mycobacterial genes were published some five years ago. Mycobacteriologists, bacterial geneticists, and those with an interest in microbial pathogenesis will find this volume to be invaluable.
Download or read book Mycobacterium written by Tanya Parish and published by Caister Academic Press Limited. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, expert scientists critically review the current and most recent advances in the genomics and molecular biology of mycobacteria. With the focus being on the topical and most relevant aspects, the contributors provide insight into the current understanding of the subject and the future direction of research. Topics covered include strain variation and evolution, hypervirulent strains, electron transport and respiration, lipid biosynthesis, DNA repair, oxygen signaling, sulphur metabolism, protein secretion, the protein kinase family, and much more. This is a valuable reference text for all microbiology laboratories and is essential reading for all scientists and researchers involved with mycobacteria.
Download or read book Molecular Genetics of Bacteria written by Jeremy Dale and published by . This book was released on 1998-05-05 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetics of Bacteria Third Edition Jeremy W. Dale School of Biological Sciences, University of Surrey, UK This third edition of Jeremy Dale's successful book provides a thoroughly updated and revised introduction to the molecular biology and genetics of bacteria. Molecular Genetics of Bacteria presents both the basic concepts and the most exciting recent developments in a form which is suitable for the needs of students studying microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences. The structure of the third edition has undergone a major reorganization and incorporates: * New material on the concept of adaptive mutation, bacterial differentiation, intercellular signalling, conjugative transposons and integrons. * Enhanced coverage of supercoiling, reporter genes, sporulation, PCR and genome sequencing projects. Reviews of the Second Edition: "I recommend this book strongly for the purpose for which it was designed, namely as an introductory text with broad coverage of the subject." Simon Baumberg, University of Leeds, Society for General Microbiology Quarterly ". a text that is readable and attractive to people who may be daunted by more-detailed works." Trends in Microbiology
Download or read book Molecular Genetics of Bacteria written by Larry Snyder and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Mycobacteriology written by Robert A. Ollar and published by CRC Press. This book was released on 1999-01-04 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents an overview of the clinical pathology of mycobacterial and nonpathogens, data on genetically based methodologies for clinical testing, straightforward protocols for molecular manipulations, and theoretical explanations of the molecular mechanisms involved. It explains the safest and most efficient methods for detecting mycobacterium avium complex, providing the means to combat this common secondary opportunistic infection in AIDS patients.
Download or read book Mycobacteria Protocols written by Tanya Parish and published by Springer Science & Business Media. This book was released on 1998 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory experts present cutting-edge molecular biology techniques for studying the mycobacteria, a medically significant group of organisms responsible for both human and animal disease, including tuberculosis and leprosy. The methods range from basic culture techniques, cell fractionation, and nucleic acid purification to more advanced protocols for the introduction of cloned DNA into mycobacteria, the use of reporter genes, and the expression of foreign genes. There are also important techniques for mycobacteriophages, genome analysis, chemical and transposon mutagenesis, gene replacement, and analysis of gene expression, as well as such clinically useful techniques as antibiotic susceptibility testing, speciation, and RFLP analysis.
Download or read book Mycobacterium Tuberculosis Protocols written by Tanya Parish and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide detailed protocols for studying the molecular biology of the pathogen Mycobacterium tuberculosis, and its int- actions with host cells. As established mycobacterial laboratories move - wards exploiting the genome, and laboratories with expertise in other fields apply them to mycobacteria, both traditional and novel methodologies need to be reviewed. Thus the chapters in Mycobacterium tuberculosis Protocols range from perspectives on storage of strains and safety issues to the application of the latest functional genomics technologies. The last few years have been remarkable ones for research into M. tuber- losis. The most important landmark by far has been the completion of the genome sequence of the widely studied H37Rv strain (1). We can now predict every protein and RNA molecule made by the pathogen. This information is or will soon be enriched by the addition of genome sequences of other strains from the M. tuberculosis complex: a second strain of M. tuberculosis, My- bacterium bovis, and the vaccine strain, M. bovis BCG. Valuable comparative data will also be provided by the genome sequences of Mycobacterium leprae, Mycobacterium avium, and Streptomyces coelicolor. Another recent milestone for M. tuberculosis has been the development of efficient mutagenesis me- odologies, the lack of which has been a major handicap in functional studies.
Download or read book Genetics and Molecular Biology of Anaerobic Bacteria written by Madeleine Sebald and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of bacterial genetics has been restricted for many years to Escherichia coli and a few other genera of aerobic or facultatively anaerobic bacteria such as Pseudomonas, Bacillus, and Salmonella. The prevailing view up to recent times has been that anaerobic bacteria are interesting organisms but nothing is known about their genetics. To most microbiologists, anaerobic bacteria appeared as a sort of distant domain, reserved for occasional intrusions by taxonomists and medical microbiologists. By the mid-1970s, knowledge of the genetics and molecular biology of anaerobes began to emerge, and then developed rapidly. but also im This was the result of advances in molecular biology techniques, portantly because of improvements in basic techniques for culturing anaerobes and for understanding their biochemistry and other areas of in terest. Investigations in this field were also stimulated by a renewal of interest in their ecology, their role in pathology and in biotransformations, and in the search for alternative renewable sources of energy. The initial idea for this book came from Thomas D. Brock. When Dr. Brock requested my opinion about two years ago on the feasibility of publishing a book on the genetics of anaerobic bacteria, as a part of the Brock/Springer Series in Contemporary Bioscience, I answered positively but I was apprehen sive about assuming the role of editor. However, I was soon reassured by the enthusiastic commitment of those I approached to contribute. Eventually, thanks to the caring cooperation of the contributors, the task became relatively easy.
Download or read book Population Genetics of Bacteria written by Society for General Microbiology. Symposium and published by Cambridge University Press. This book was released on 1995-02-02 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: A authoritative summary of the current knowledge of the genetic organisation of bacterial populations.
Download or read book Bacterial and Bacteriophage Genetics written by Edward A. Birge and published by Springer Science & Business Media. This book was released on 2006-04-04 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic investigations and manipulations of bacteria and bacteriophage have made vital contributions to our basic understanding of living cells and to the development of molecular biology and biotechnology. This volume is a survey of the genetics of bacteria and their viruses, and it provides students with a comprehensive introduction to this rapidly changing subject. The book is written for upper level undergraduates and beginning graduate students, particularly those who have had an introductory genetics course. The fifth edition has been extensively revised to reflect recent advances in the field. The book now has a reader-friendly look, with end-of-chapter questions, "Thinking Ahead" and "Applications" boxes to challenge students’ comprehension and insights. A complete glossary of commonly used terms has been revised and expanded.
