Download or read book Molecular Evolution on Rugged Landscapes written by Alan S. Perelson and published by CRC Press. This book was released on 2018-03-08 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book lays out a number of the general issues concerning the structure of rugged fitness landscapes and examines both the history and the current status of experimental work on somatic mutation and the maturation of the immune response.
Download or read book Molecular Evolution on Rugged Landscapes written by Alan S. Perelson and published by CRC Press. This book was released on 2018-03-08 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book lays out a number of the general issues concerning the structure of rugged fitness landscapes and examines both the history and the current status of experimental work on somatic mutation and the maturation of the immune response.
Download or read book Molecular Evolution on Rugged Landscapes written by Perelson and published by . This book was released on 1991-06-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biodefense in the Age of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-05 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.
Download or read book Epistasis and the Evolutionary Process written by Jason B. Wolf and published by Oxford University Press, USA. This book was released on 2000 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last two decades, research into epistasis has seen explosive growth and has moved the focus of research in evolutionary genetics from a traditional additive approach. We now know the effects of genes are rarely independent, and to reach a fuller understanding of the process of evolution we need to look at gene interactions as well as gene-environment interactions. This book is an overview of non-additive evolutionary genetics, integrating all work to date on all levels of evolutionary investigation of the importance of epistasis in the evolutionary process in general. It includes a historical perspective on this emerging field, in-depth discussion of terminology, discussions of the effects of epistasis at several different levels of biological organization and combinations of theoretical and experimental approaches to analysis.
Download or read book The Origins of Order written by Stuart A. Kauffman and published by Oxford University Press. This book was released on 1993-06-10 with total page 958 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stuart Kauffman here presents a brilliant new paradigm for evolutionary biology, one that extends the basic concepts of Darwinian evolution to accommodate recent findings and perspectives from the fields of biology, physics, chemistry and mathematics. The book drives to the heart of the exciting debate on the origins of life and maintenance of order in complex biological systems. It focuses on the concept of self-organization: the spontaneous emergence of order that is widely observed throughout nature Kauffman argues that self-organization plays an important role in the Darwinian process of natural selection. Yet until now no systematic effort has been made to incorporate the concept of self-organization into evolutionary theory. The construction requirements which permit complex systems to adapt are poorly understood, as is the extent to which selection itself can yield systems able to adapt more successfully. This book explores these themes. It shows how complex systems, contrary to expectations, can spontaneously exhibit stunning degrees of order, and how this order, in turn, is essential for understanding the emergence and development of life on Earth. Topics include the new biotechnology of applied molecular evolution, with its important implications for developing new drugs and vaccines; the balance between order and chaos observed in many naturally occurring systems; new insights concerning the predictive power of statistical mechanics in biology; and other major issues. Indeed, the approaches investigated here may prove to be the new center around which biological science itself will evolve. The work is written for all those interested in the cutting edge of research in the life sciences.
Download or read book The Adaptive Landscape in Evolutionary Biology written by Erik Svensson and published by Oxford University Press. This book was released on 2012-05-17 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 'Adaptive Landscape' has been a central concept in population genetics and evolutionary biology since this powerful metaphor was first formulated in 1932. This volume brings together historians of science, philosophers, ecologists, and evolutionary biologists, to discuss the state of the art from several different perspectives.
Download or read book Theoretical Aspects of Evolutionary Computing written by Leila Kallel and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the first week of September 1999, the Second EvoNet Summer School on Theoretical Aspects of Evolutionary Computing was held at the Middelheim cam pus of the University of Antwerp, Belgium. Originally intended as a small get together of PhD students interested in the theory of evolutionary computing, the summer school grew to become a successful combination of a four-day workshop with over twenty researchers in the field and a two-day lecture series open to a wider audience. This book is based on the lectures and workshop contributions of this summer school. Its first part consists of tutorial papers which introduce the reader to a num ber of important directions in the theory of evolutionary computing. The tutorials are at graduate level andassume only a basic backgroundin mathematics and com puter science. No prior knowledge ofevolutionary computing or its theory is nec essary. The second part of the book consists of technical papers, selected from the workshop contributions. A number of them build on the material of the tutorials, exploring the theory to research level. Other technical papers may require a visit to the library.
Download or read book The Origins of Order written by Stuart A. Kauffman and published by . This book was released on 1993 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph extends the basic concepts of Darwinian evolution to accommodate recent findings and perspectives from the fields of biology, physics, chemistry and mathematics. It explains how complex systems, contrary to expectations, can spontaneously exhibit degrees of order.
Download or read book Cellular Automata and Cooperative Systems written by N. Boccara and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the lectures given at the NATO Advanced Study Institute on `Cellular Automata and Cooperative Systems', held at Les Houches, France, from June 22 to July 2, 1992. The book contains contributions by mathematical and theoretical physicists and mathematicians working in the field of local interacting systems, cellular probabilistic automata, statistical physics, and complexity theory, as well as the applications of these fields.
Download or read book Origins written by Joseph Seckbach and published by Springer. This book was released on 2006-05-07 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book forty eminent scientists examine the astrobiological origins of life and the emergence of biodiversity in extreme environments. The coverage includes extremophiles: microbes living in hostile conditions of high temperature, psychrophilic, UV radiation, and halophilic environments. Also discussed are the origin and history of Martian water, and the possible biogeochemistry inside Titan.
Download or read book Molecular Evolution On Rugged Landscapes written by Alan S Perelson and published by Westview Press. This book was released on 1991-06-23 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Mind The Brain And Complex Adaptive Systems written by Harold J. Morowitz and published by Routledge. This book was released on 2018-03-08 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based upon a conference held in May 1993, this book discusses the intersection of neurobiology, cognitive psychology and computational approaches to cognition.
Download or read book Algebraic Engineering Proceedings Of The First International Conference On Semigroups And Algebraic Eng And Workshop On For written by Chrystopher L Nehaniv and published by World Scientific. This book was released on 1999-05-14 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is algebraic structure in time, computation and biological systems. Algebraic engineering exploits this structure to achieve better understanding and design. In this book, pure and applied results in semigroups, language theory and algebra are applied to areas ranging from circuit design to software engineering to biological evolution.
Download or read book Modularity written by Werner Callebaut and published by MIT Press. This book was released on 2005 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modularity—the attempt to understand systems as integrations of partially independent and interacting units—is today a dominant theme in the life sciences, cognitive science, and computer science. The concept goes back at least implicitly to the Scientific (or Copernican) Revolution, and can be found behind later theories of phrenology, physiology, and genetics; moreover, art, engineering, and mathematics rely on modular design principles. This collection broadens the scientific discussion of modularity by bringing together experts from a variety of disciplines, including artificial life, cognitive science, economics, evolutionary computation, developmental and evolutionary biology, linguistics, mathematics, morphology, paleontology, physics, theoretical chemistry, philosophy, and the arts. The contributors debate and compare the uses of modularity, discussing the different disciplinary contexts of "modular thinking" in general (including hierarchical organization, near-decomposability, quasi-independence, and recursion) or of more specialized concepts (including character complex, gene family, encapsulation, and mosaic evolution); what modules are, why and how they develop and evolve, and the implication for the research agenda in the disciplines involved; and how to bring about useful cross-disciplinary knowledge transfer on the topic. The book includes a foreword by the late Herbert A. Simon addressing the role of near-decomposability in understanding complex systems. Contributors: Lee Altenberg, Lauren W. Ancel-Meyers, Carl Anderson, Robert B. Brandon, Angela D. Buscalioni, Raffaele Calabretta, Werner Callebaut, Anne De Joan, Rafael Delgado-Buscalioni, Gunther J. Eble, Walter Fontana, Fernand Gobet, Alicia de la Iglesia, Slavik V. Jablan, Luigi Marengo, Daniel W. McShea, Jason Mezey, D. Kimbrough Oller, Domenico Parisi, Corrado Pasquali, Diego Rasskin-Gutman, Gerhard Schlosser, Herbert A. Simon, Roger D. K. Thomas, Marco Valente, Boris M. Velichkovsky, Gunter P. Wagner, Rasmus G. Winter Vienna Series in Theoretical Biology
Download or read book Evolutionary Dynamics written by James Patrick Crutchfield and published by Oxford University Press, USA. This book was released on 2003 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 14 chapters of this volume, which present an overview of new research in evolutionary dynamics, were first presented at a conference held in October 1998 at the Santa Fe Institute. The main divisions of the book are macroevolution; epochal evolution; population genetics, dynamics, and optimization; and evolution of cooperation. Individual topics include spectral landscape theory, external triggers in biological evolution, and evolutionary dynamics of asexual reproduction. Several of the contributors, like the editors, are affiliated with the Sante Fe Institute; others teach or work in physics, genetics, biology, computational neuroscience, and theoretical chemistry at universities and private institutions in the US, UK, Austria, Sweden, Australia, Israel, and Germany. Annotation copyrighted by Book News, Inc., Portland, OR
Download or read book Robust Design written by Erica Jen and published by Oxford University Press. This book was released on 2005-03-03 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Robust Design brings together 16 chapters by an eminent group of authors in a wide range of fields presenting aspects of robustness in biological, ecological, and computational systems. The volme is the first to address robustness in biological, ecological, and computational systems. It is an outgrowth of a new research program on robustness at the Sante Fe Institute founded by the David and Lucile Packard Foundation. For those interested in complexity or interdisciplinary science, robustness is seen as currently among the most intellectually active and promising research areas with important applications in all fields of science, business, and economics.
