Download or read book Molecular Endocrinology of the Steroid Hormones written by Dennis Schulster and published by . This book was released on with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Endocrinology of the Steroid Hormones written by Dennis Schulster and published by John Wiley & Sons. This book was released on 1976-01-01 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gene Regulation by Steroid Hormones written by A.K. Roy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last two decades endocrinological research has taken a definite tum toward biochemistry and molecular biology. This has resulted in a new discipline called' 'molecular endocrinology. " Studies on the mechanism of hormone action have continued to make headlines with fundamental discov eries in receptor action and gene regulation. Recently the insect endocrino logists have also begun to explore the molecular mechanism of steroid hor mone action taking advantage of the vast number of Drosophila mutants, the library of Drosophila gene, and several well-characterized cell-lines. The availability ofthe recombinant DNA technology has provided a truly revolu tionary tool in the hands of the molecular endocrinologists. "Gene Regula tion by Steroid Hormones" is compiled and presented in this frontier spirit, and we hope that this volume will serve not only the active investigators in the field but will also be very useful to students and researchers with a gen eral interest in regulatory biology. The book is an offshoot of the Conference on Molecular Mechanism of Steroid Hormone Action held at the Meadow Brook Mansion of Oakland University in the fall of 1978. We wish to acknowledge the financial assist ance from the National Science Foundation and Oakland University. The conferees will never forget the warmest hospitality of Dr. LOWELL EKLUND and his staff at the Meadow Brook center and we also wish to express per sonal gratitude to many of our students and colleagues for helping us to make the conference a great success.
Download or read book Molecular Endocrinology written by Gill Rumsby and published by Garland Science. This book was released on 2020-07-26 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the Human Molecular Genetics series is an invaluable text for endocrinologists wishing to update their knowledge. It also provides an excellent grounding in the basic genetics of molecular endocrinology and relevant analytical techniques.
Download or read book Gene Regulation by Steroid Hormones III written by Arun K. Roy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of steroid hormone action has continued to expand into the realm of molecular biology at a pace even faster than most of us ever imagined. techniques of molecular biology have made it possible to clone The hormone-regulated genes and to examine steroid-receptor interactions with these genes. Nucleotide sequences of these genes, which show preferential binding of steroid receptors, have been identified. These results are complemented by the identification of chromatin acceptor proteins, which also show preferential binding for steroid-receptor complexes. Thus, one can envision the day when cloned genes, purified acceptor proteins, and receptor-steroid complexes will be recombined in vitro to form a functional unit. Cellular localization of steroid receptors has undergone recent revision, and it now appears that receptors are localized primarily in the nuclear compartment. These findings, although controversial, will lead to a reassessment of many of the previous concepts of steroid-receptor interactions and regulation. The way in which these observations at the of physiology, molecular and cellular levels fit into the overall scheme development, and evolution are continuing to progress, and the future promises some very exciting syntheses of understanding at all levels of biological organization. The third Meadow Brook Conference on hormones was held in order to bring together investigators who will undoubtedly contribute heavily to this future synthesis and to permit a free exchange of ideas and concepts as they relate to the current state-of-the-art in molecular endocrinology. Spring 1986 ARUN K. Roy JAMES H. CLARK Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Download or read book Molecular Endocrinology and Steroid Hormone Action written by Gordon Sato and published by Wiley-Liss. This book was released on 1990 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This broad-ranging volume reveals that the study of steroid hormone action has permeated many areas of biology and medicine. Focusing on major unanswered questions, it offers valuable insights regarding the hormonal regulation of gene expression. A diverse group of biologists, biochemists, molecular biologists, and researchers explore various aspects of steroid hormone receptors as they discuss the structure and function of receptors and steroid hormone receptors as trans-acting factors. Molecular Endocrinology and Steroid Hormone Action also covers steroid hormone modification, highlighting the role of receptor phosphorylation in hormonal regulation, and steroid hormone function in biology and pathobiology, focusing on the interplay of steroid hormones with growth factors. There is also discussion of steroid use in cancer therapy.
Download or read book Hormones written by Etienne-Emile Baulieu (ed) and published by Springer Science & Business Media. This book was released on 1990-11-30 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrinology is a field in which enormous advances have been made in the last decade; the rate of discovery of new hormones, hormone-like molecules, receptors, and mechanisms of action is continually advancing. The development of techniques in immunology and molecular biology has led to the possibility of describing in detail the gene structure of many of the compounds involved in hormonal systems. Remarkable homology has been shown between oncogene products and various components of the endocrine network, leading to the asser tion that deregulation of hormonal function is involved in the generation and/or development of cancer. We now know that the central nervous system is both a target and a production site of many hormonal products, and that hormones, neurotransmitters, growth factors and immunopeptides all act through similar mechanisms. The only second messenger known ten years ago was cAMP; today calcium, derivatives of membrane phospholipids, and protein kinases are also known to be mediators of hormone action. The very concept of hormonal systems has been expanded to include not only endocrine secretions but also para- and autohormones and their mechanisms of action; an understanding of their functions will be central to the immediate future of medicine. The discovery of hormonal molecules and endocrine interactions and the subsequent understanding of hormone related pathophysiology has led to the development of new strategies in medical treatment such as fertility control and the management of diabetes.
Download or read book Steroid Hormone Action and Cancer written by K. Menon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is an outgrowth of a symposium held at the University of Michigan, Ann Arbor, Michigan, October 27-29, 1975. This symposium was organized to bring together basic scientists and clinicians for the purpose of exchanging new ideas and the latest information in the area of Steroid Hormone Action and Cancer. The design of the symposium included both formal plenary sessions and informal roundtable discussion groups, the chapters of this volume being drawn primarily from these proceedings. During the last quarter of a century considerable progress has been made toward understanding the molecular mechanisms in volved in steroid hormone action. It now appears that the mechan sim of action of the four major classes of steroid hormones is qualitatively similar. Research during the past decade has demonstrated steroid hormone receptors in a variety of normal and neoplastic tissues. Receptor-containing neoplasms have been shown to be hormone-dependent and undergo regression when treated with hormone antagonists. Natural and synthetic steroids also have been employed for many years to successfully treat various types of cancer, for example: estrogens, androgens and progestagens for breast cancer; estrogens and progestagens for prostatic carcinoma; progestagens for endometrial carcinoma; and corticoids for leu kemias. All of these neoplasms have now been found to possess receptors for the steroids empirically used in their treatment.
Download or read book Molecular Endocrinology and Steroid Hormone Action written by Gordon H. Sato and published by Wiley-Liss. This book was released on 1989-12-21 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This broad-ranging volume reveals that the study of steroid hormone action has permeated many areas of biology and medicine. Focusing on major unanswered questions, it offers valuable insights regarding the hormonal regulation of gene expression. A diverse group of biologists, biochemists, molecular biologists, and researchers explore various aspects of steroid hormone receptors as they discuss the structure and function of receptors and steroid hormone receptors as trans-acting factors. Molecular Endocrinology and Steroid Hormone Action also covers steroid hormone modification, highlighting the role of receptor phosphorylation in hormonal regulation, and steroid hormone function in biology and pathobiology, focusing on the interplay of steroid hormones with growth factors. There is also discussion of steroid use in cancer therapy.
Download or read book Steroid Receptors in Health and Disease written by Virinder Moudgil and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, progress in steroid hormone research has resulted in the development of new approaches to contraception as well as diagnosis and treatment of endocrine disorders and cancers. Although significant advances have been made in the purification, characterization, immunochemistry and molecular biology of steroid receptors, the precise molecular mechanism of steroid hormone action has remained obscure. This book captures the detailed presentations made at the first conference on Steroid Receptors in Health and Disease held at Meadow Brook Hall, Oakland University in the fall of 1987. The purpose of this international con ference was to facilitate scientific exchange toward a better understand ing of the mode of action of steroid hormones. The scientific sessions consisted of poster presentations and state-of-the-art lectures, the latter of which make up this volume. The first chapter is meant to provide the reader with a more general background of the topics covered in the book, as well as to discuss certain theme-related issues that are either not yet well-established or accepted or are in the stage of infancy. It is hoped that this volume will serve as a useful treatise for students and investigators interested in basic and clinical aspects of biological regulation by steroid hormones. A task of this magnitude could not have been undertaken without the encouragement, advice and continued generous assistance of the members of the scientific committee. I am gratefully indebted to Drs.
Download or read book Molecular Endocrinology written by Franklyn F. Bolander and published by Academic Press. This book was released on 2013-10-22 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at graduate level courses, this textbook provides students with a solid background in the basics of molecular endocrinology. Molecular Endocrinology, Second Edition, summarizes the area and provides an in-depth discussion of the molecular aspects of hormone action, including hormone-receptor interactions, second messenger generation, gene induction, and post-transcriptional control. Thoroughly revised and updated, the Second Edition includes new information on growth factors, hematopoietic-immune factors, nonclassical hormones, receptors, transduction, transcriptional regulation, as well as other relevant topics. Incorporating an abundance of new information, this text retains the self-contained, focused, and easily readable style of the First Edition. Professionals in related fields will also find this book to be a helpful summary and general reference source.
Download or read book Hormones written by Anthony W. Norman and published by Academic Press. This book was released on 2014-06-28 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones provides a comprehensive treatment of human hormones viewed in the light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. The book begins with discussions of the first principles of hormone action and the seven classes of steroid hormones and their chemistry, biosynthesis, and metabolism. These are followed by separate chapters that address either a classical endocrine system, e.g., hypothalamic hormones, posterior pituitary hormones, anterior pituitary hormones, ,thyroid hormones, pancreatic hormones, gastrointestinal hormones, calcium regulating hormones, adrenal corticoids, hormones of the adrenal medulla, androgens, estrogens and progestins, and pregnancy and lactation hormones; or newer domains of hormone action which are essential to a comprehensive understanding of hormone action, including prostaglandins, thymus hormones, and pineal hormones. The book concludes with a presentation of hormones of the future, i.e., cell growth factors. This book is intended for use by first-year medical students, graduate students, and advanced undergraduates in the biological sciences. It is also hoped that this book will fill the void that exists for resource materials for teaching cellular and molecular endocrinology and that it will be employed as an equal partner with most standard biochemistry textbooks to provide a comprehensive and balanced coverage of this realm of biology.
Download or read book Molecular and Cellular Endocrinology written by E. Edward Bittar and published by Elsevier. This book was released on 1997 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cell Endocrinology.
Download or read book Molecular Endocrinology written by Bruce D. Weintraub and published by Lippincott Williams & Wilkins. This book was released on 1995 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gene Regulation by Steroid Hormones II written by A.K. Roy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptors and Gene Expression It is now more than three years since the last Meadow Brook Conference on Hormones, and a great deal has happened in the meantime. We have become comfortable with the totally unanticipated fact that the coding sequences of genes are in discontinuous arrangements and that the RNA transcribed from them must be extensively processed to form messenger RNA. We have also learned about the strategy of "mixing and matching" of genetic segments so that a small amount of DNA can go a long way in producing a huge variety of different proteins, as in the immunoglobulin system. The explosive effort directed toward DNA sequence analysis has led us to the conclusion that there are signals within the DNA that specify sites of transcription initiation and possibly sites for interacting with regulatory molecules such as hor mones and their receptors. The current intense interest in the structure of chromatin beyond the nucleosome-that is, the superstructural characteris tics of the genetic material-is finally yielding meaningful results that give promise for understanding the regulation of gene activity. ROBERT F. GOLDBERGER Preface Research on the molecular mechanism of steroid hormone action continues at an extraordinary pace and a great deal of progress has been made. Steroid hormones have been localized on target genes providing the long awaited evidence for the concept of a direct effect of the steroid-receptor complex on gene regulation. Purified steroid receptors have been dissected to identify different functional domains.
Download or read book Molecular Endocrinology and Steroid Hormone Action written by Gordon H. Sato and published by . This book was released on 1990 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Schering Symposium on Biodynamics and Mechanism of Action of Steroid Hormones Berlin March 14 to 16 1968 written by Gerhard Raspé and published by Elsevier. This book was released on 2013-10-22 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Biosciences 2 documents the proceedings of the Schering Symposium on Biodynamics and Mechanism of Action of Steroid Hormones held in Berlin, on 14-16 March 1968. The volume begins by presenting the opening address on the symposium's main themes followed by a lecture on the factors influencing the nature and significance of research in the biological sciences. The papers presented cover topics such as methods for automatic and semi-automatic assay of steroids; the combination of gas chromatography and mass spectrometry for the investigation of complex mixtures; factors controlling steroid hormone metabolism; and the metabolism of free and conjugated estrogens. Other studies deal with the molecular basis of estrogen-binding in target cells; early biochemical events in the mouse testis associated with ultimate induction of interstitial cell tumors by estrogens; biochemical features of androgens; and effects of corticosteroid administration on rats. This book also presents panel discussions on the clinical aspects, biodynamics, and action of steroid hormones.
