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Book Molecular Design and Synthesis of Coumarin Fluorescent Dyes

Download or read book Molecular Design and Synthesis of Coumarin Fluorescent Dyes written by Chih Hung Lui and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Systematic Exploration of Indolizine Based Small Fluorescent Molecules

Download or read book Systematic Exploration of Indolizine Based Small Fluorescent Molecules written by Youngjun Lee and published by Springer. This book was released on 2018-08-16 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter. Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working under live cell conditions. Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.

Book Industrial Dyes

    Book Details:
  • Author : Klaus Hunger
  • Publisher : John Wiley & Sons
  • Release : 2007-09-24
  • ISBN : 3527606068
  • Pages : 648 pages

Download or read book Industrial Dyes written by Klaus Hunger and published by John Wiley & Sons. This book was released on 2007-09-24 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: What would life be like without color? Ever since one can think back, color has always accompanied mankind. Dyes - originally obtained exclusively from natural sources - are today also produced synthetically on a large scale and represent one of the very mature and traditional sectors of the chemical industry. The present reference work on Industrial Dyes provides a comprehensive review of the chemistry, properties and applications of the most important groups of industrial dyes, including optical brighteners. It also outlines the latest developments in the area of functional dyes. Renowned experts in their respective fields have contributed to the chapters on chemical chromophores, synthesis and application of the various dye classes, textile dyeing and non-textile dyeing. The book is aimed at all professionals who are involved in the synthesis, production, manufacture or application of dyes and will prove to be an indispensable guide to all chemists, engineers and technicians in dye science and industry.

Book Advanced Fluorescence Reporters in Chemistry and Biology I

Download or read book Advanced Fluorescence Reporters in Chemistry and Biology I written by Alexander P. Demchenko and published by Springer Science & Business Media. This book was released on 2010-09-08 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorescence reporter is the key element of any sensing or imaging technology. Its optimal choice and implementation is very important for increasing the sensitivity, precision, multiplexing power, and also the spectral, temporal, and spatial reso- tion in different methods of research and practical analysis. Therefore, design of ?uorescence reporters with advanced properties is one of the most important problems. In this volume, top experts in this ?eld provide advanced knowledge on the design and properties of ?uorescent dyes. Organic dyes were the ?rst ?uorescent materials used for analytical purposes, and we observe that they retain their leading positions against strong competition of new materials – conjugated polymers, semiconductor nanocrystals, and metal chelating complexes. Recently, molecular and cellular biology got a valuable tool of organic ?uorophores synt- sized by cell machinery and incorporated into green ?uorescent protein and its analogs. Demands of various ?uorescence techniques operating in spectral, anisotropy, and time domains require focused design of ?uorescence reporters well adapted to these techniques. Near-IR spectral range becomes more and more attractive for various applications, and new dyes emitting in this range are strongly requested. Two-photonic ?uorescence has become one of the major tools in bioimaging, and ?uorescence reporters well adapted to this technique are in urgent need. These problems cannot be solved without the knowledge of fundamental principles of dye design and of physical phenomena behind their ?uorescence response.

Book Fluorescent Analogs of Biomolecular Building Blocks

Download or read book Fluorescent Analogs of Biomolecular Building Blocks written by Marcus Wilhelmsson and published by John Wiley & Sons. This book was released on 2016-04-04 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorescent Analogs of Biomolecular Building Blocks focuses on the design of fluorescent probes for the four major families of macromolecular building blocks. Compiling the expertise of multiple authors, this book moves from introductory chapters to an exploration of the design, synthesis, and implementation of new fluorescent analogues of biomolecular building blocks, including examples of small-molecule fluorophores and sensors that are part of biomolecular assemblies.

Book Photochemistry of Organic Compounds

Download or read book Photochemistry of Organic Compounds written by Petr Klán and published by John Wiley & Sons. This book was released on 2009-03-23 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photochemistry of Organic Compounds: From Concepts to Practice provides a hands-on guide demonstrating the underlying principles of photochemistry and, by reference to a range of organic reaction types, its effective use in the synthesis of new organic compounds and in various applications. The book presents a complete and methodical approach to the topic, Working from basic principles, discussing key techniques and studies of reactive intermediates, and illustrating synthetic photochemical procedures. Incorporating special topics and case studies covering various applications of photochemistry in chemistry, environmental sciences, biochemistry, physics, medicine, and industry. Providing extensive references to the original literature and to review articles. Concluding with a chapter on retrosynthetic photochemistry, listing key reactions to aid the reader in designing their own synthetic pathways. This book will be a valuable source of information and inspiration for postgraduates as well as professionals from a wide range of chemical and natural sciences.

Book Design  Synthesis  and Characterization of Mechanosensitive Dual Fluorescent Dyes as Potential Probes for Biological Applications

Download or read book Design Synthesis and Characterization of Mechanosensitive Dual Fluorescent Dyes as Potential Probes for Biological Applications written by Susantha Ganegamage and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter 3 of this dissertation explores a hypothesis that leverages the seesaw photophysical model for N-aryl (2,3- and 1,8-) naphthalimides. The Heagy group initially developed this model to understand the dual fluorescence effect concerning the electron donor or electron-withdrawing substituents. This study envisions the design and synthesis of novel dual fluorescence molecules for a new class of N-aryl-phenanthridinone dyes. The applied photophysical model further investigates these dyes with a substitution pattern opposite naphthalimide systems. Interestingly, predictive computational modeling shows that the substituent pattern, used previously for 2,3-naphthalimides, relies on these groups getting placed on rings in opposite positions for N-aryl-phenanthridinones. Chapter 4, provides an overall conclusion of the and future directions for both parts of the research. In chapter 5, a complete description of experimental data is provided for the characterization of all the dye systems presented. This data includes a detailed synthesis procedure, characterization, purity analysis by HPLC, absorptivity calculation, fluorescence lifetime measurements, quantum yield determination, biological evaluation and fluorescence titration.

Book Antimicrobial Textiles

    Book Details:
  • Author : Gang Sun
  • Publisher : Woodhead Publishing
  • Release : 2016-04-11
  • ISBN : 0081005857
  • Pages : 374 pages

Download or read book Antimicrobial Textiles written by Gang Sun and published by Woodhead Publishing. This book was released on 2016-04-11 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial textiles have attracted a great deal of interest in recent years due to their potential for reducing the transmission of infection in medical and healthcare environments. Antimicrobial properties can also improve the performance and lifespan of consumer products, and so these fabrics are increasingly finding applications in the wider textile and apparel industry. This book provides systematic coverage of the technologies and materials required for developing these important textiles. In Part One, chapters address key issues and technologies in the creation of antimicrobial textile products. Topics covered include testing and regulation, microencapsulation, sol-gel coating and plasma technologies, nanotechnology and life cycle assessment. Part Two then reviews key antimicrobial agents, such as N-halamines, plant based compounds and photo-active chemicals. Finally, the chapters of Part Three offer detailed reviews of antimicrobial textiles for particular important applications, including medical devices, protective clothing and products with improved durability and longevity. Reviews key issues and technologies in the creation of antimicrobial textile products Offered a detailed overview of by antimicrobial agents and a wide range of important applications Produced by an experienced editor and a distinguished and international team of contributors

Book Chromic Phenomena 3rd Edition

    Book Details:
  • Author : Peter Bamfield
  • Publisher : Royal Society of Chemistry
  • Release : 2018-08-24
  • ISBN : 1782628150
  • Pages : 812 pages

Download or read book Chromic Phenomena 3rd Edition written by Peter Bamfield and published by Royal Society of Chemistry. This book was released on 2018-08-24 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromic or colour related phenomena are produced in response to a chemical or physical stimulus. This new edition will update the information on all those areas where chemicals or materials interact with light to produce colour, a colour change, or luminescence especially in the imaging, analysis, lighting and display areas. The book has been restructured to show greater emphasis on applications where 'coloured' compounds are used to transfer energy or manipulate light in some way therefore reducing the details on classical dyes and pigments. In the past eight years, since the previous edition, there has been a remarkable increase in the number of papers and reviews being produced reflecting the growth of interest in this area. This ongoing research interest is matched by a large number of new technological applications gaining commercial value covering e.g. biomedical areas, energy, data storage, physical colour, bio-inspired materials and photonics. This book appeals to industrial chemists, professionals, postgraduates and as high level recommended reading for colour technology courses.

Book Handbook of Fluorescent Dyes and Probes

Download or read book Handbook of Fluorescent Dyes and Probes written by R. W. Sabnis and published by John Wiley & Sons. This book was released on 2015-06-02 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: A COMPLETE, UP-TO-DATE RESOURCE OF INFORMATION ON MORE THAN 150 FLUORESCENT DYES AND PROBES Handbook of Fluorescent Dyes and Probes is the most comprehensive volume available on the subject, covering all the available dyes and probes known to date in the literature for uses in various fields. Top dye expert Dr. Ram Sabnis organizes the compounds alphabetically by the most commonly used chemical name. He presents an easy-to-use reference complete with novel ideas for breakthrough research in medical, biological, chemical, color, material, physical and related allied fields. The ease of use of the handbook is further enhanced by various appendixes provided at the end of the book to conveniently and easily locate the dye as per the reader's need. This is the first book to give the CAS registry numbers, chemical structure, Chemical Abstract (CA) index name, all other chemical names, Merck Index number, chemical/dye class, molecular formula, molecular weight, physical form, solubility, melting point, boiling point, pKa, absorption maxima, emission maxima, molar extinction coefficient, and quantum yield of fluorescent dyes and probes, as well as to provide access to synthetic procedures (lab scale and industrial scale) of dyes and probes in a single source. This user-friendly handbook also features references on safety, toxicity and adverse effects of dyes and probes on humans, animals and the environment, including: acute/chronic toxicity aquatic toxicity carcinogenicity cytotoxicity ecotoxicity genotoxocity hematotoxicity hepatotoxicity immunotoxicity marine toxicity microbial toxicity mutagenicity nephrotoxicity neurotoxicity nucleic acid damage oral toxicity phototoxicity phytotoxicity reproductive toxicity skin toxicity Containing imaging/labeling applications, biological/medical applications and industrial applications, Handbook of Fluorescent Dyes and Probes is a convenient, vital resource for industrial and academic researchers, and a valuable desktop reference for medical professionals, lab supervisors, scientists, chemists, biologists, engineers, physicists, intellectual property professionals, students, and professors. Includes all fluorescent dyes & probes known to date and provides a complete, up-to-date library of information in one reference/handbook Includes more than 300 fluorescent dyes & probes organized alphabetically by the commonly used Chemical Name Provides access to synthesis procedures (lab scale and industrial scale) of fluorescent dyes & probes First book to provide references on safety, toxicity and adverse effects of fluorescent dyes and probes on humans, animals, and the environment User-friendly and convenient resource guide for chemical, biological, medical, and intellectual property professionals in a broad range of disciplines

Book

    Book Details:
  • Author :
  • Publisher :
  • Release : 2002
  • ISBN :
  • Pages : pages

Download or read book written by and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Click Triazoles

    Book Details:
  • Author : Janez Košmrlj
  • Publisher : Springer
  • Release : 2012-05-30
  • ISBN : 3642294294
  • Pages : 245 pages

Download or read book Click Triazoles written by Janez Košmrlj and published by Springer. This book was released on 2012-05-30 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: B. R. Buckley and H. Heaney: Mechanistic Investigations of Copper(I)- Catalyzed Alkyne–Azide Cycloaddition Reactions.- J. D. Crowley and D. A. McMorran: “Click-Triazole” Coordination Chemistry: Exploiting 1,4-Disubstituted-1,2,3-Triazoles as Ligands.- S. Lee and A. H. Flood: Binding Anions in Rigid and Reconfigurable Triazole Receptors.- M. Watkinson: Click Triazoles as Chemosensors.- H.-F. Chow, C.-M. Lo and Y. Chen: Triazole-Based Polymer Gels.- T. Zheng, S. H. Rouhanifard, A. S. Jalloh, P. Wu: Click Triazoles for Bioconjugation.- S. Mignani, Y. Zhou, T. Lecourt and L. Micouin: Recent Developments in the Synthesis 1,4,5-Trisubstituted Triazoles.

Book Coumarin and Its Derivatives

Download or read book Coumarin and Its Derivatives written by Maria João Matos and published by Mdpi AG. This book was released on 2021-12-29 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coumarins are widely distributed in nature and can be found in a large number of naturally occurring and synthetic bioactive molecules. The unique and versatile oxygen-containing heterocyclic structure makes them a privileged scaffold in Medicinal Chemistry. Many coumarin derivatives have been extracted from natural sources, designed, synthetized, and evaluated on different pharmacological targets. In addition, coumarin-based ion receptors, fluorescent probes, and biological stains are growing quickly and have extensive applications to monitor timely enzyme activity, complex biological events, as well as accurate pharmacological and pharmacokinetic properties in living cells. The extraction, synthesis, and biological evaluation of coumarins have become extremely attractive and rapidly developing topics. A large number of research and review papers have compiled information on this important family of compounds in 2020. Research articles, reviews, communications, and concept papers focused on the multidisciplinary profile of coumarins, highlighting natural sources, most recent synthetic pathways, along with the main biological applications and theoretical studies, were the main focus of this book. The huge and growing range of applications of coumarins described in this book is a demonstration of the potential of this family of compounds in Organic Chemistry, Medicinal Chemistry, and different sciences related to the study of natural products. This book includes 23 articles: 17 original papers and six review papers.

Book Phytochemicals in Human Health

Download or read book Phytochemicals in Human Health written by Venketeshwer Rao and published by BoD – Books on Demand. This book was released on 2020-02-12 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Naturally present bioactive compounds in plants are referred to as "Phytochemicals" and are being studied extensively for their role in human health. Studies have shown that they can have an important role to play in the prevention and management of several human diseases. Recognizing the increasing interest in this area, this book is being published in response to the need for more current information globally about phytochemicals and their role in human health. Chapters of the book are authored by internationally recognized authors who are experts in their respective field of expertise. The chapters represent both original research as well as up-to-date and comprehensive reviews. We are sure that the book will be an important reference source meeting the needs of a wide range of interest groups.

Book Design  Synthesis and Application of Ultrastable Rylene Dyes for Fluorescent Labeling of Biomolecules

Download or read book Design Synthesis and Application of Ultrastable Rylene Dyes for Fluorescent Labeling of Biomolecules written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies of organic fluorescent dyes are experiencing a renaissance related to the increasing demands posed by new microscopy techniques for high resolution and high sensitivity. While in the last decade single molecule equipment and methodology has significantly advanced and in some cases reached theoretical limits (e.g. detectors approaching unity quantum yields) unstable emission from chromophores and photobleaching become more and more the bottleneck of the advancement and spreading of single-molecule fluorescence studies. The main goal of this work was the synthesis of fluorophores that are water-soluble, highly fluorescent in an aqueous environment, have a reactive group for attachment to a biomolecule and posses exceptional photostability. An approach towards highly fluorescent, water-soluble and monofunctional perylene-3,4,9,10-tetracarboxdiimide and terrylene-3,4:11,12-tetra carboxidiimide chromophores was presented. A new synthetic strategy for the desymmetrization of perylenetetracarboximides was elaborated; water-solubility was accomplished by introducing sulfonyl substituents in the phenoxy ring. Two strategies have been followed relying on either non-specific or site specific labeling. For this purpose a series of new water-soluble monofunctional perylene and terrylene dyes, bearing amine or carboxy group were prepared. The reactivity and photophysical properties of these new chromophores were studied in aqueous medium. The most suitable chromophores were further derivatized with amine or thiol reactive groups, suitable for chemical modification of proteins. The performance of the new fluorescent probes was assessed by single molecule enzyme tracking, in this case phospholipase acting on phospholipid supported layers. Phospholipase-1 (PLA-1) was labeled with N-hydroxysuccinimide ester functionalized perylene and terrylene derivatives. The purification of the conjugates was accomplished by novel convenient procedure for the removal of unreacted dye from.

Book Fluorescent Probes

    Book Details:
  • Author :
  • Publisher : Academic Press
  • Release : 2021-05-13
  • ISBN : 0128235438
  • Pages : 284 pages

Download or read book Fluorescent Probes written by and published by Academic Press. This book was released on 2021-05-13 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorescent Probes, Volume 48 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting chapters on important topics, including Hydrogel microarray technology as a tool for clinical diagnostics, The use of probes and bacteriophages for bacteria detection, Probes used with point-of-care microfluidic devices for pathogen detection, Methods for combining FIB/SEM with three-dimensional fluorescence microscopy using CLEM approaches, Probes and Microbes, Microbial signatures associated with cancers, Fluorescent Aptamers for Detection and Treatment of Pathogenic Bacteria and Cancer, Labelled and Unlabeled Probes for Pathogen Detection with Molecular Biology Methods and Biosensors, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Microbiology series