Download or read book Modified Cyclodextrins for Chiral Separation written by Weihua Tang and published by Springer Science & Business Media. This book was released on 2013-05-24 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modified Cyclodextrins for Chiral Separation offers a review of the latest advances in developing modified cyclodextrins as chiral selectors for various chromatographic and electromigration techniques. Over the years, many descriptions of chiral separation have appeared in academic journals and books, but most of them have been devoted to either the development of analytical methods and protocols or the summary of different chiral selectors, including cyclodextrins for chiral separation applications. This is in marked contrast to this volume which focuses on the research endeavors concerning the development of cyclodextrin derivatives specifically as either chiral mobile phases for capillary electrophoresis, or chiral stationary phases for various chromatographic techniques including gas chromatography, or high-performance liquid chromatography and supercritical fluid chromatography. The ongoing thread in this book is the synthesis of structurally-defined cyclodextrin derivatives and their applications in enantiomer separation by means of different analytical techniques. Modified Cyclodextrins for Chiral Separation is intended for those who are interested in expanding their knowledge of cyclodextrin chemistry and chiral separation, and in what cyclodextrin modification can be made to suit the needs of chiral selectors for different analytical techniques. It primarily focuses on the state-of-the-art cyclodextrin chemistry which is the basis for all chiral selectors used in these chiral separation techniques. Weihua Tang, PhD, is a professor at the Key Laboratory of Soft Chemistry and Functional Materials, Ministry of Education, Nanjing University of Science and Technology, China. Siu-Choon Ng, PhD, is a professor at the Division of Chemical and Biomedical Engineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore. Dongping Sun, PhD, is a professor at the Key Laboratory of Soft Chemistry and Functional Materials, Ministry of Education, Nanjing University of Science and Technology, China.
Download or read book Gas Chromatographic Enantiomer Separation with Modified Cyclodextrins written by Wilfried A. König and published by . This book was released on 1992 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modified Cyclodextrins Scaffolds And Templates For Supramolecular Chemistry written by Chris J Easton and published by World Scientific. This book was released on 1999-04-29 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through modification, the natural cyclodextrins are effective templates for the generation of a wide range of molecular hosts. This makes it possible to tailor a cyclodextrin host to a particular guest, to meet specific requirements in the host-guest complex, and opens the way to diverse new areas of supramolecular chemistry. Metallocyclodextrins, rotaxanes and catenanes, as well as surface monolayers of modified cyclodextrins, are readily obtained. The native cyclodextrins serve as scaffolds on which functional groups and other substituents can be assembled, with controlled geometry. This results in substantially improved molecular recognition and procedures for chemical separation, including enantiomer discrimination, through guest binding. Access to the gamut of functional groups greatly expands the utility of cyclodextrins in chemical synthesis and provides catalysts which mimic the entire range of enzymic activity. Modifications to the cyclodextrins also lead to a wide range of photochemistry of cyclodextrin complexes, through which the enhancement of guest reactivity occurs; in addition, light harvesting molecular devices and photochemical frequency switches may be constructed. In solution, modified cyclodextrins have been used to construct molecular reactors, as well as molecular, temperature and pH sensors. At surfaces, they form semipermeable membranes and sensor electrodes. Such exciting fields of chemistry, made possible only through modifications to the natural cyclodextrins, are the subject of this book.
Download or read book Modified Cyclodextrins written by Christopher J. Easton and published by Imperial College Press. This book was released on 1999-01-01 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through modification, the natural cyclodextrins are effective templates for the generation of a wide range of molecular hosts. This makes it possible to tailor a cyclodextrin host to a particular guest, to meet specific requirements in the host -- guest complex, and opens the way to diverse new areas of supramolecular chemistry. Metallocyclodextrins, rotaxanes and catenanes, as well as surface monolayers of modified cyclodextrins, are readily obtained. The native cyclodextrins serve as scaffolds on which functional groups and other substituents can be assembled, with controlled geometry. This results in substantially improved molecular recognition and procedures for chemical separation, including enantiomer discrimination, through guest binding. Access to the gamut of functional groups greatly expands the utility of cyclodextrins in chemical synthesis and provides catalysts which mimic the entire range of enzymic activity. Modifications to the cyclodextrins also lead to a wide range of photochemistry of cyclodextrin complexes, through which the enhancement of guest reactivity occurs; in addition, light harvesting molecular devices and photochemical frequency switches may be constructed. In solution, modified cyclodextrins have been used to construct molecular reactors, as well as molecular, temperature and pH sensors. At surfaces, they form semipermeable membranes and sensor electrodes. Such exciting fields of chemistry, made possible only through modifications to the natural cyclodextrins, are the subject of this book.
Download or read book Cyclodextrins in Chromatography written by Tibor Cserháti and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyclodextrins can form complexes with a wide variety of organic and inorganic compounds, a property which can prove useful when trying to separate complex mixtures. This book provides an up-to-date and critical evaluation of the application of cyclodextrins in many fields of chromatography (including thin layer, gas-liquid, high performance liquid and supercritical fluid chromatography; capillary electrophoresis; and isotacophoresis). Whilst mainly practical in nature, the book also looks briefly at the theoretical background for the various techniques. Any professional working with chromatography will welcome this unique book as both a practical compilation of methods and a source of reference to the literature regarding the use and impact of cyclodextrins in chromatography.
Download or read book Chiral Separations by Capillary Electrophoresis written by Ann Van Eeckhaut and published by CRC Press. This book was released on 2009-11-11 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers the Fundamentals of Chiral Separation, Available Chiral Selectors, and Numerous Applications of Chiral Separation by Capillary ElectrophoresisSince the 1980s, modern analytical tools have enabled capillary electrophoresis to become a standard part of the chemist's toolkit. With contributions from international experts, Chiral Separations by
Download or read book Chiral Separations and Stereochemical Elucidation written by Quezia Bezerra Cass and published by John Wiley & Sons. This book was released on 2023-03-29 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: An expert resource for chemists using stereochemical analysis methods In Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications, a team of distinguished researchers delivers a robust and authoritative discussion of the theoretical fundamentals of chiral separation, the most commonly used chiral selectors, and stereochemical elucidation methods. The book offers expert discussions of a variety of chiral separation methods by gas chromatography (GC), supercritical fluid chromatography (SFC), capillary electrophoresis (CE), and liquid chromatography (LC). The authors also describe several methods for stereochemical elucidation, including X-ray crystallography, nuclear magnetic resonance spectroscopy, and chiroptical methods. The explored material is ideal for practicing chemists seeking a resource to help them guide method development and optimization or to explain quality control-complements during target compound production. Readers will also find: A thorough introduction to the most important advances and applications in LC, GC, CE, SFC, and preparative chromatography Comprehensive explorations of the role of 2D-LC for chiral separation methods development and applications Practical discussions of the design, mechanisms, and applications of the most commonly used chiral selectors Fulsome treatments of the theoretical backgrounds, advantages, limitations, and applications of stereochemical elucidation methods Perfect for academic and industrial chemists specially in organic, analytical chemistry and pharmaceutical analysis. Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications will also benefit biochemists, environmental analysts, forensic and medicinal chemists as well as natural product chemists and those involved with stereochemistry or structural elucidation.
Download or read book Cyclodextrins Preparation And Application In Industry written by Jin Zhengyu and published by World Scientific. This book was released on 2018-01-03 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyclodextrins are an extremely versatile class of chemicals highly prized for their ability to incorporate a plethora of organic, inorganic and biologic guest molecules into their hydrophobic cavities and form host-guest inclusion complexes. As excellent molecular receptors, they have long been exploited in many important industries such as food and agriculture, pharmaceuticals, cosmetics, textiles, analytical chemistry and enzyme mimics. Researchers, technicians and application specialists in many industries will appreciate this handy volume that systematically discusses how cyclodextrins are applied in their industries. Special attention is devoted to the preparation of inclusion complexes, novel properties of the resultant complexes, and details on applying those properties to industry. Contents: Introduction (Junrong Huang, Qi Yang, and Huayin Pu)General Methods for the Preparation of Cyclodextrin Inclusion Complexes (Jinpeng Wang, Haoran Fan, and Mengke Zhang)Applications in Food (Chao Yuan, Wangyang Shen, Bo Yu, and Xing Zhou)Applications in Agriculture (Jianwei Zhao and Shengjun Wu)Applications in Pharmaceuticals (Xiuting Hu and Yaoqi Tian)Applications in Cosmetics (Tao Feng, Haining Zhuang, and Na Yang)Applications in the d104ile Industry (Jin Xu)Applications in Analytical Chemistry (Xuehong Li)Cyclodextrin-Based Enzyme Mimics (Aiquan Jiao) Readership: Researchers, technicians and application specialists in food and agriculture, pharmaceuticals, cosmetics, textiles, analytical chemistry and environmental engineering industries. Keywords: Cyclodextrins;Preparation;Application;IndustryReview: Key Features: Shows researchers and technologists how to use cyclodextrins as host compounds and further promote related researchCovers seven fields in one volumeDiscusses the preparation of the inclusion complexes and the important properties of the resultant complexes are covered in detail
Download or read book Chiral Separations written by Gerald Gübitz and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prominent experts from around the world detail the chromatographic and electroseparation techniques they have developed for chiral separations on an analytical scale. Described in step-by-step detail to ensure successful experimental results, the procedures are presented as either general methods or as specific applications to substance classes and special compounds, with emphasis on high performance liquid chromatography and capillary electrophoresis techniques, but also including thin layer chromotographic, gas chromatographic, supercritical fluid chromatographic as well as recent electrochromotographic techniques.
Download or read book Chiral Separations written by Bezhan Chankvetadze and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Differentiation of Enantiomers I written by Volker Schurig and published by Springer. This book was released on 2013-12-16 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Download or read book PCBs written by Larry G. Hansen and published by University of Illinois Press. This book was released on 2023-12-11 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though polychlorinated biphenyls (PCBs) have been banned in the United States for more than thirty years, the toxic effects of their presence in local environments continue to be a significant public health concern. PCBs: Human and Environmental Disposition and Toxicology brings together more than fifty established specialists on PCB toxicity to discuss recent trends and specialized investigations of PCB influences on the environment and on humans. Renowned scientists including Paul S. Cooke, Takeshi Nakano, Tomas Trnovec, Deborah C. Rice, Linda S. Birnbaum, and Charles S. Wong present cutting-edge research on Hudson River PCBs, human contamination, homologue profiles, high PCB exposure in Slovakia, and PCB effects on the thyroid hormone, nutrition, and estrogen levels in humans and animals. Focusing on the detection, movement, metabolism, toxicity, remediation, and risk assessment of PCB contamination, this multi-disciplinary study is a valuable resource for regulatory agencies and scientists working with PCBs.
Download or read book Chiral Separation Methods for Pharmaceutical and Biotechnological Products written by Satinder Ahuja and published by John Wiley & Sons. This book was released on 2011-03-31 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.
Download or read book Chiral Organic Pollutants written by Edmond Sanganyado and published by CRC Press. This book was released on 2020-12-30 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chiral Organic Pollutants introduces readers to the growing challenges of chirality in synthetic chemicals. In this volume, contributors brilliantly summarize the characteristics of chiral pollutants to provide tools and techniques for effectively assessing their environmental and human health risks. Chapters cover recent research on the physicochemical properties, sources, exposure pathways, environmental fate, toxicity, and enantioselective analysis of chiral organic pollutants. Chiral Organic Pollutants also provides comprehensive discussions on the current trends in the synthesis and legislation of chiral chemicals. Key Features: Includes sampling and analytical methods for the enantioselective analysis of a wide array of chiral organic pollutants in food and the environment Summarizes recent research on the sources, fate, transport, and toxicity of chiral organic pollutants in the environment Critically examines the sources and pathways of chiral organic pollutants such as pesticides, pharmaceuticals, and flame retardants in food Includes a comprehensive discussion on current trends in the enantioselective synthesis and chiral switching of pesticides and pharmaceuticals Provides analysis of current national and international regulations of chiral synthetic chemicals The use of chiral synthetic chemicals such as pesticides, pharmaceuticals, personal care products, and halogenated flame retardants has significantly grown in the past 60 years. Hence, understanding the human and environmental health effects of chiral organic pollutants is crucial in the industry, academia, and policymaking. Chiral Organic Pollutants is an excellent textbook and reference for students, scientists, engineers, and policymakers interested in food quality, environmental pollution, chemical analysis, organic synthesis, and toxicology. Also available in the Food Analysis and Properties Series: Analysis of Nanoplastics and Microplastics in Food, edited by Leo. M.L. Nollet and Khwaja Salahuddin Siddiqi (ISBN: 9781138600188) Proteomics for Food Authentication, edited by Leo M.L. Nollet, and Semih Ötleş (ISBN: 9780367205058) Mass Spectrometry Imaging in Food Analysis, edited by Leo M.L. Nollet (ISBN: 9781138370692) For a complete list of books in this series, please visit our website at: www.crcpress.com/Food-Analysis--Properties/book-series/CRCFOODANPRO
Download or read book Selected Topics in the Chemistry of Natural Products written by Raphael Ikan and published by World Scientific. This book was released on 2008 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times Notable Book for 2011 A Globe and Mail Best Books of the Year 2011 Title A Kirkus Reviews Best Nonfiction of 2011 title Virtually all human societies were once organized tribally, yet over time most developed new political institutions which included a central state that could keep the peace and uniform laws that applied to all citizens. Some went on to create governments that were accountable to their constituents. We take these institutions for granted, but they are absent or are unable to perform in many of today’s developing countries—with often disastrous consequences for the rest of the world. Francis Fukuyama, author of the bestselling The End of History and the Last Man and one of our most important political thinkers, provides a sweeping account of how today’s basic political institutions developed. The first of a major two-volume work, The Origins of Political Order begins with politics among our primate ancestors and follows the story through the emergence of tribal societies, the growth of the first modern state in China, the beginning of the rule of law in India and the Middle East, and the development of political accountability in Europe up until the eve of the French Revolution. Drawing on a vast body of knowledge—history, evolutionary biology, archaeology, and economics—Fukuyama has produced a brilliant, provocative work that offers fresh insights on the origins of democratic societies and raises essential questions about the nature of politics and its discontents.
Download or read book Chiral Analysis written by Kenneth W. Busch and published by Elsevier. This book was released on 2011-10-13 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chiral Analysis covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals. The target audience is scientific professionals with an undergraduate background in chemistry or a related discipline, specifically organic chemists, researchers in drug discovery, pharmaceutical researchers involved with process analysis or combinatorial libraries, and graduate students in chemistry. Chapters have been written with the nonspecialist in mind so as to be self-contained. * Broad coverage - spectroscopic and separation methods covered in a single volume * Up-to-date and detailed review of the various techniques available and/or under development in this field * Contributions from leading experts in the field
Download or read book Capillary Electrophoresis in Chiral Analysis written by Bezhan Chankvetadze and published by John Wiley & Sons. This book was released on 1997-12-29 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Das weltweite Interesse an der Trennung von Enantiomeren, Spiegelbildern ein und derselben chemischen Verbindung, nimmt zu, da diese Formen beispielsweise verschiedene physiologische Wirkungen hervorrufen können. Eine hochaktuelle Technik der Stofftrennung in diesem Zusammenhang ist die Kapillarelektrophorese, die hier von den theoretischen Grundlagen bis hin zu analytischen Details und Anbieterlisten ausführlich beschrieben wird.
