Download or read book Modelling Degradation of Bioresorbable Polymeric Medical Devices written by J Pan and published by Elsevier. This book was released on 2014-10-24 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling. Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates

Download or read book Degradation Rate of Bioresorbable Materials written by F J Buchanan and published by Elsevier. This book was released on 2008-09-26 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioresorbable materials are extensively used for a wide range of biomedical applications from drug delivery to fracture fixation, and may remain in the body for weeks, months or even years. Accurately predicting and evaluating the degradation rate of these materials is critical to their performance and the controlled release of bioactive agents. Degradation rate of bioresorbable materials provides a comprehensive review of the most important techniques in safely predicting and evaluating the degradation rate of polymer, ceramic and composite based biomaterials. Part one provides an introductory review of bioresorbable materials and the biological environment of the body. Chapters in Part two address degradation mechanisms of commonly used materials such as polymers and ceramics. This is followed by chapters on bioresorption test methods and modelling techniques in Part three. Part four discusses factors influencing bioresorbability such as sterilisation, porosity and host response. The final section reviews current clinical applications of bioresorbable materials. With its distinguished editor and multidisciplinary team of international contributors, Degradation rate of bioresorbable materials: prediction and evaluation provides a unique and valuable reference for biomaterials scientists, engineers and students as well as the medical community. Comprehensively reviews the most pertinent techniques in safely predicting and evaluating the degradation rate of bioresorbable materials Addresses degradation mechanisms of commonly used materials Discusses factors influencing bioresorbability such as sterilisation and host response

Download or read book A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites written by Ismael Moreno-Gomez and published by Springer. This book was released on 2019-04-05 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation. It then combines this modelling framework with a comprehensive database of quantitative degradation data mined from existing literature and from novel experiments, to provide new insights into the interrelated factors controlling degradation. Resorbable composites made of biodegradable polyesters and calcium-based ceramics have significant therapeutic potential as tissue engineering scaffolds, as temporary implants and as drug-loaded matrices for controlled release. However, their degradation is complex and the rate of resorption depends on multiple connected factors such as the shape and size of the device, polymer chemistry and molecular weight, particle phase, size, volume fraction, distribution and pH-dependent dissolution properties. Understanding and ultimately predicting the degradation of resorbable composites is of central importance if we are to fully unlock the promise of these materials.

Download or read book Bioresorbable Polymers for Biomedical Applications written by Giuseppe Perale and published by Woodhead Publishing. This book was released on 2016-08-24 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine provides readers with an overview of bioresorbable polymeric materials in the biomedical field. A useful resource for materials scientists in industry and academia, offering information on the fundamentals and considerations, synthesis and processing, and the clinical and R and D applications of bioresorbable polymers for biomedical applications. Focuses on biomedical applications of bioresorbable polymers Features a comprehensive range of topics including fundamentals, synthesis, processing, and applications Provides balanced coverage of the field with contributions from academia and industry Includes clinical and R and D applications of bioresorbable polymers for biomedical applications

Download or read book Science and Principles of Biodegradable and Bioresorbable Medical Polymers written by Xiang Cheng Zhang and published by Woodhead Publishing. This book was released on 2016-09-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers. Provides a practical guide to the fundamentals, synthesis, and processing of bioresorbable polymers in medicine Contains comprehensive coverage of material properties, including unique insights into modeling degradation Written by an eclectic mix of international authors with experience in academia and industry

Download or read book Durability and Reliability of Medical Polymers written by Mike Jenkins and published by Elsevier. This book was released on 2012-08-13 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the widespread use of polymers in medical devices, the durability and reliability of this material in use is an area of critical importance. Durability and reliability of medical polymers reviews the performance of both bioresorbable and non-bioresorbable medical polymers. Part one provides a review of the types and properties of bioresorbable medical polymers. The effect of molecular structure on properties is discussed, along with the processing of bioresorbable and other polymers for medical applications. Transport phenomena and the degradation of bioresorbable medical polymers are reviewed, before an exploration of synthetic bioresorbable polymers and their use in orthopaedic tissue regeneration. Part two goes on to explore the durability and reliability of non-bioresorbable medical polymers, and wear processes in polymer implants and ageing processes of biomedical polymers in the body are discussed in depth, before an investigation into manufacturing defects and the failure of synthetic polymeric medical devices. With its distinguished editors and international team of expert contributors, Durability and reliability of medical polymers is an essential tool for all materials scientists, researchers and engineers involved in the design, development and application of medical polymers, whilst also providing a helpful overview of the subject for biologists, chemist and clinicians. Comprehensively examines the performance of both bioresorbable and non-bioresorbable medical polymers Discusses the processing of bioresorbable and other polymers for medical applications, before reviewing the degradation of bioresorbable medical polymers Explores the durability and reliability of non-bioresorbable medical polymers and discusses wear processes in polymer implants and ageing processes of biomedical polymers in the body

Download or read book Handbook of Polymer Applications in Medicine and Medical Devices written by Zheng Zhang and published by Elsevier Inc. Chapters. This book was released on 2013-12-05 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The design and development of tissue-engineered products has benefited from many years of clinical utilization of a wide range of biodegradable polymers. Newly developed biodegradable polymers and modifications of previously developed biodegradable polymers have enhanced the tools available for creating clinically important tissue-engineering applications. Insights gained from studies of cell-matrix interactions, cell-cell signaling, and organization of cellular components, are placing increased demands on medical implants to interact with the patient’s tissue in a more biologically appropriate fashion. Whereas in the twentieth century biocompatibility was largely equated with eliciting no harmful response, the biomaterials of the twenty first century will have to elicit tissue responses that support healing or regeneration of the patient’s own tissue. This chapter surveys the universe of those biodegradable polymers that may be useful in the development of medical implants and tissue-engineered products. Here, we distinguish between biologically derived polymers and synthetic polymers. The materials are described in terms of their chemical composition, breakdown products, mechanism of breakdown, mechanical properties, and clinical limitations. Also discussed are product design considerations in processing of biomaterials into a final form (e.g., gel, membrane, matrix) that will effect the desired tissue response.

Download or read book Bioresorbable Polymers and their Composites written by Deepak Verma and published by Elsevier. This book was released on 2023-12-01 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioresorbable Polymers and their Composites: Characterization and Fundamental Processing for Pharmaceutical and Medical Device Development provides a holistic view of these unique materials and their usage in a range of biomedical applications. The book is evenly divided between fundamentals, processing methods and modeling approaches, and includes detailed coverage of a variety of applications, such as drug delivery, medical devices and wound healing. Key aspects including biocompatibility, biodegradability and toxicology are also thoroughly covered, enabling the reader to be fully informed when fabricating and utilizing their selected bioresorbable polymer. This book is an interdisciplinary and important reference for researchers in the fields of materials science, biomedical engineering, pharmaceutical science and regenerative medicine, as well as R&D groups in the development of medical devices. Introduces the reader to various processing and modeling techniques for bioresorbable polymers, including electrospinning, molecular and finite element modeling Covers a range of key bioresorbable composites, such as PCL, PLA/PLLA and PHA/PHB/PHBV Explores a wide selection of biomedical applications of bioresorbable polymers, from tissue engineering and stents, to biosensors and medical devices/implants

Download or read book Materials for Biomedical Engineering Absorbable Polymers written by Alexandru Grumezescu and published by Elsevier. This book was released on 2019-06-28 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Materials for Biomedical Engineering: Absorbable Polymers provides a detailed and comprehensive review of recent progress in absorbable biopolymers and their impact on biomedical engineering. The book's main focus lies in their classification, processing, properties and performance, biocompatibility, and their applications in tissue engineering, drug delivery, bone repair and regenerative medicine. The most up-to-date methods used to obtain such polymers and how to improve their properties is discussed in detail. This book provides readers with a comprehensive and updated review of the latest research in the field of absorbable polymers for biomedical applications. Provides knowledge of the range of absorbable polymers currently available, enabling the reader to make optimal materials selection decisions Presents detailed information on current and proposed applications of the latest developments Includes a strong emphasis on chemistry and physico-chemical characterization of these materials and their application in biomedical engineering

Download or read book Shape Memory Polymers for Biomedical Applications written by L Yahia and published by Elsevier. This book was released on 2015-03-19 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shape memory polymers (SMPs) are an emerging class of smart polymers which give scientists the ability to process the material into a permanent state and predefine a second temporary state which can be triggered by different stimuli. The changing chemistries of SMPs allows scientists to tailor important properties such as strength, stiffness, elasticity and expansion rate. Consequently SMPs are being increasingly used and developed for minimally invasive applications where the material can expand and develop post insertion. This book will provide readers with a comprehensive review of shape memory polymer technologies. Part 1 will discuss the fundamentals and mechanical aspects of SMPs. Chapters in part 2 will look at the range of technologies and materials available for scientific manipulation whilst the final set of chapters will review applications. Reviews the fundamentals of shape memory polymers with chapters focussing on the basic principles of the materials Comprehensive coverage of design and mechanical aspects of SMPs Expert analysis of the range of technologies and materials available for scientific manipulation

Download or read book Medical Modelling written by Richard Bibb and published by Woodhead Publishing. This book was released on 2014-12-13 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical modelling and the principles of medical imaging, Computer Aided Design (CAD) and Rapid Prototyping (also known as Additive Manufacturing and 3D Printing) are important techniques relating to various disciplines - from biomaterials engineering to surgery. Building on the success of the first edition, Medical Modelling: The application of Advanced Design and Rapid Prototyping techniques in medicine provides readers with a revised edition of the original text, along with key information on innovative imaging techniques, Rapid Prototyping technologies and case studies.Following an overview of medical imaging for Rapid Prototyping, the book goes on to discuss working with medical scan data and techniques for Rapid Prototyping. In this second edition there is an extensive section of peer-reviewed case studies, describing the practical applications of advanced design technologies in surgical, prosthetic, orthotic, dental and research applications. Covers the steps towards rapid prototyping, from conception (modelling) to manufacture (manufacture) Includes a comprehensive case studies section on the practical application of computer-aided design (CAD) and rapid prototyping (RP) Provides an insight into medical imaging for rapid prototyping and working with medical scan data

Download or read book Degradation Phenomena on Polymeric Biomaterials written by Heinrich Planck and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tradi tionally, the International lTV - Conferences on Biomate rials are focussing on problems in Biomedical Engineering, problems, which are still unsolved, of main interest, and which are of interdisciplinary character. In 1983, the Division of Biomedical Engineering of the Institute of Textile Technology and Chemical Engineering, Denkendorf, started wi th a conference about the use of polyurethanes in biomedicine. Three years later,. in 1986, progress in development and use of polyurethanes was selected as conference topic. It had to be realized that degradation problems were still dominating the discussions. The main discussion topics were: What are the causes for the degradation? How can one prevent them? What are the degradation products, and do they affect the human body? How can one simu late the degradation? How can one accelerate the in vitro tests and how can the results predict the in vivo behaviour of the material? How do in vitro tests correlate with animal tests and the behaviour in the human body? At the third conference in 1989, the speakers focused on the use of textiles in medicine. Again the problem of degradation was discussed intensively and demonstrated by the failure of textile implants, the degradation of aramide polymers or the degradation of resorbable suture materials. The examples make clear, that degradation may be a desired or undesired property of an implant.

Download or read book Bioresorbable Polymers and their Biomedical Applications written by Declan M Devine and published by Smithers Rapra. This book was released on 2017-04-10 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioresorbable or biodegradable polymers are commonly used in various biomedical applications. The application of bioresorbable polymers in the biomedical sector has been widely exploited by immobilising suturing thread with an analgesic or antibacterial drugs, and the development of bioresorbable vascular scaffolds, wound-healing and intravenous drug-delivery devices. Furthermore, biodegradable polymers have been investigated as a replacement for metallic orthopaedic devices due to their precise control of material composition and microstructure. These polymers are eliminated from the body via dissolution, assimilation and excretion through metabolic pathways. The hydrolysing process breaks down the polymer into smaller units and its degradation products are excreted by means of the citric acid cycle or by direct renal excretion with no residual side effects.Processing of bioresorbable implants can be achieved via conventional polymer processing methods such as extrusion, injection and compressing moulding, solvent spinning or casting. However, special consideration must be given when processing these materials because heat can cause a reduction in molecular weight due to the hydrolysing of bonds. In addition, overheating can depolymerise the polymer and, as a result, monomers can have a plasticising effect on the polymer. Recently, alternative approaches utilising rapid prototyping and micro-/nanofabrication processes have been employed.This book addresses these issues and highlights recent advances in the biomedical field that have being enabled by the use of biodegradable polymers. This book is designed as a reference guide for academic researchers utilising biodegradable polymers in a range of areas from tissue engineering to controlled release of active pharmaceuticals, through to industry-based processors of biodegradable polymers.

Download or read book Medical Devices written by Seeram Ramakrishna and published by Woodhead Publishing. This book was released on 2015-08-18 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Devices and Regulations: Standards and Practices will shed light on the importance of regulations and standards among all stakeholders, bioengineering designers, biomaterial scientists and researchers to enable development of future medical devices. Based on the authors’ practical experience, this book provides a concise, practical guide on key issues and processes in developing new medical devices to meet international regulatory requirements and standards. Provides readers with a global perspective on medical device regulations Concise and comprehensive information on how to design medical devices to ensure they meet regulations and standards Includes a useful case study demonstrating the design and approval process

Download or read book Biosynthetic Polymers for Medical Applications written by Laura Poole-Warren and published by Elsevier. This book was released on 2015-11-23 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosynthetic Polymers for Medical Applications provides the latest information on biopolymers, the polymers that have been produced from living organisms and are biodegradable in nature. These advanced materials are becoming increasingly important for medical applications due to their favorable properties, such as degradability and biocompatibility. This important book provides readers with a thorough review of the fundamentals of biosynthetic polymers and their applications. Part One covers the fundamentals of biosynthetic polymers for medical applications, while Part Two explores biosynthetic polymer coatings and surface modification. Subsequent sections discuss biosynthetic polymers for tissue engineering applications and how to conduct polymers for medical applications. Comprehensively covers all major medical applications of biosynthetic polymers Provides an overview of non-degradable and biodegradable biosynthetic polymers and their medical uses Presents a specific focus on coatings and surface modifications, biosynthetic hydrogels, particulate systems for gene and drug delivery, and conjugated conducting polymers

Download or read book Biodegradable Polymer Based Food Packaging written by Abhishek Dutt Tripathi and published by Springer Nature. This book was released on 2022-10-20 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers different aspects of biodegradable packaging, such as their sourcing and application in food industries. The book focuses on the production and characterization of biodegradable food packaging derived from plant, animal and microbial sources. Chapters highlight the nano-technological interventions in biodegradable food packaging and the less studied microbial biopolymer-based biodegradable food packaging makes it distinct from other related books. It includes the latest research and development in the areas of food processing, food packaging, material science and polymeric science. It also discusses the standards and regulatory guidelines about the biodegradability testing of these polymers. This book is meant for researchers in food science, food packaging, bioprocess technology, polymer science and biochemical engineering. It is also beneficial for faculty members and students of food microbiology, food technology, dairy technology. The book is also meant for small entrepreneurs and farmers who are interested in bio-plastic usage for food packaging.

Download or read book Resorbable Fiber Forming Polymers for Biotextile Applications written by Chirag R. Gajjar and published by Springer. This book was released on 2014-07-05 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the properties and applications of conventional and commercially available fiber-forming, bioresorbable polymers, as well as those currently under study, for use as biotextiles. Factors affecting the performance of these biomaterials are presented, and precautionary measures to reduce premature, hydrolytic degradation during manufacturing and processing are discussed. Because of the structural requirements of medical devices and the technological advancements in synthetic fibers and textile technology, the new field of "Biotextiles" has evolved to exploit the potential of various woven, knitted, braided and non-woven textile structures for biomedical applications. Textile substrates provide certain unique mechanical properties to the medical device and because of an inherently high level of porosity, they can encourage cell growth and promote migration and proliferation. Bioresorbable devices that assist in the repair and regeneration of damaged tissues have in recent years replaced many of the permanent prosthetic devices. Thus, the topic of “Bioresorbable Biomaterials” generates much interest and research activity in the field of biomaterials science today. For this reason, the use of bioresorbable polymers as fibers is currently dominating the field of resorbable biomaterials for applications from sutures to tissue engineering scaffolds.