Download or read book Modeling the 3D Conformation of Genomes written by Guido Tiana and published by CRC Press. This book was released on 2019-01-15 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the cell nucleus. Chapters explain how to convert raw experimental data into 3D conformations, and how to use models to better understand biophysical mechanisms that control chromosome conformation. The coverage ranges from introductory chapters to modeling aspects related to polymer physics, and data-driven models for genomic domains, the entire human genome, epigenome folding, chromosome structure and dynamics, and predicting 3D genome structure.
Download or read book Modeling the 3D Conformation of Genomes written by Guido Tiana and published by CRC Press. This book was released on 2019-01-15 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the cell nucleus. Chapters explain how to convert raw experimental data into 3D conformations, and how to use models to better understand biophysical mechanisms that control chromosome conformation. The coverage ranges from introductory chapters to modeling aspects related to polymer physics, and data-driven models for genomic domains, the entire human genome, epigenome folding, chromosome structure and dynamics, and predicting 3D genome structure.
Download or read book Hi C Data Analysis written by Silvio Bicciato and published by Humana. This book was released on 2021-08-21 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details a comprehensive set of methods and tools for Hi-C data processing, analysis, and interpretation. Chapters cover applications of Hi-C to address a variety of biological problems, with a specific focus on state-of-the-art computational procedures adopted for the data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Hi-C Data Analysis: Methods and Protocols aims to help computational and molecular biologists working in the field of chromatin 3D architecture and transcription regulation.
Download or read book Essays in Bioinformatics written by David S. Moss and published by IOS Press. This book was released on 2005 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Barley Genome written by Nils Stein and published by Springer. This book was released on 2018-08-18 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of the state-of-the-art in barley genome analysis, covering all aspects of sequencing the genome and translating this important information into new knowledge in basic and applied crop plant biology and new tools for research and crop improvement. Unlimited access to a high-quality reference sequence is removing one of the major constraints in basic and applied research. This book summarizes the advanced knowledge of the composition of the barley genome, its genes and the much larger non-coding part of the genome, and how this information facilitates studying the specific characteristics of barley. One of the oldest domesticated crops, barley is the small grain cereal species that is best adapted to the highest altitudes and latitudes, and it exhibits the greatest tolerance to most abiotic stresses. With comprehensive access to the genome sequence, barley’s importance as a genetic model in comparative studies on crop species like wheat, rye, oats and even rice is likely to increase.
Download or read book Statistical Physics of Macromolecules written by and published by Amer Inst of Physics. This book was released on 1994 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents an introduction to the field of statistical physics of macromolecules, from the basic concepts to modern achievements. Applications in various fields of polymer physical chemistry and molecular biophysics are also covered, as are: the fundamentals of statistical theory of polymer solutions and melts; classical, sealing and renormalization group approaches; the main ideas of statistical theories of polymer liquid crystals, polymer networks and polyelectrolytes; dynamic viscoelastic behavior of polymer systems; models of house, Zimm and reptation concepts; and specific features of main biopolymers - DNA and proteins. This English edition also includes sections describing the most important recent advances such as: statistical theory of DNA gel-electrophoresis, polymers at interfaces, and dynamics of concentrated solutions of rigid polymers.
Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Download or read book Molecular Modeling and Simulation written by Tamar Schlick and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 669 pages. Available in PDF, EPUB and Kindle. Book excerpt: Very broad overview of the field intended for an interdisciplinary audience; Lively discussion of current challenges written in a colloquial style; Author is a rising star in this discipline; Suitably accessible for beginners and suitably rigorous for experts; Features extensive four-color illustrations; Appendices featuring homework assignments and reading lists complement the material in the main text
Download or read book Computational Biochemistry and Biophysics written by Oren M. Becker and published by CRC Press. This book was released on 2001-02-09 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering theoretical methods and computational techniques in biomolecular research, this book focuses on approaches for the treatment of macromolecules, including proteins, nucleic acids, and bilayer membranes. It uses concepts in free energy calculations, conformational analysis, reaction rates, and transition pathways to calculate and interpret b
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromosome Structure and Aberrations written by Tariq Ahmad Bhat and published by Springer. This book was released on 2017-02-08 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of various chapters contributed by a group of leading researchers from different countries and covering up to date information based on published reports and personal experience of authors in the field of cytogenetics. Beginning with the introduction of chromosome, the subsequent chapters on organization of genetic material, karyotype evolution, structural and numerical variations in chromosomes, B-chromosomes and chromosomal aberrations provide an in-depth knowledge and easy understanding of the subject matter. A special feature of the book is the inclusion of a series of chapters on various types of chromosomal aberrations and their impact on breeding behaviour and crop improvement. The possible mechanism, their consequences and role in genetic analysis has been emphasized in these chapters. A few chapters have also been dedicated on various techniques routinely used in the laboratory by students and researchers. Each chapter ends with an extensive bibliography so that the students and researchers may find it relevant to consult more literature on the subject than a book of this size can offer. The book is intended to fulfill the needs of undergraduate and post graduate students of botany, zoology and agriculture besides, teachers and researchers engaged in the field of genetics, cytogenetics, and molecular genetics. In general the readers will find each chapter of the book informative and easy to understand.
Download or read book Intelligent Systems and Automation written by Hichem Arioui and published by American Institute of Physics. This book was released on 2008-06-17 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: All papers have been peer-reviewed. The ‘Intelligent Systems and Automation’ conference will be organized for its first edition between June 30th and July 02nd, 2008, where it will be held at Annaba, in Algeria (Africa). CISA encourages the diverse research actors and the industrial one to present the last headways in "Robotics and Automation" fields, notably the experimental demonstration of prototypes. CISA tries to give to the unsupported researchers, a significant access to the new technologies and theories around the topics of Robotics & Automation. The organizers want to give the necessary scientific documents to disposal of the PhD students and researchers of the Mediterranean region. CISA wants to offer to the youth researchers from the south Mediterranean region the opportunities to exchange and to discuss their scientific contributions with the other researchers from all over the world.
Download or read book Proceedings written by and published by . This book was released on 2004 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genomes Molecular Biology and Drug Discovery written by M. J. Browne and published by . This book was released on 1996 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until recently, the traditional model of pharmaceutical research had been applied to programs of genetic study, resulting in the many therapeutic agents either under developed or in clinical usage. However, a shift in emphasis is currently taking place towards the so-called "Genome Projects" which enable the identification of gene sequences on a much larger scale and have established gene therapy as a more viable route to treatment. They have also forced pharmaceutical research to its "watershed". Genomes, Molecular Biology, and Drug Discovery is based on the 7th SmithKline Beecham International Symposium and attempts to bring the continuing advances in modern genome research and molecular biology together with new pharmacological and chemical strategies sharply into focus. It highlights the need for a multi-disciplinary approach in order to direct the wealth of information accumulated towards better community healthcare and close the drug discovery loop. Genome Projects * Interpreting the Code * From Gene to Target * From Target to Therapy * Conclusions and Challenges
Download or read book Chemical Abstracts written by and published by . This book was released on 2002 with total page 2668 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bioinformatics written by Thomas Lengauer and published by . This book was released on 2002 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: V.1: Basic technologies: From Genomes to drugs with bioinformatics (Thomas Lengauer); Sequence analysis (Martin Vingron); Structure, properties and computer identification of eukaryotic genes (Victor Solovyev). Analyzing regulatory regions in genomes (Thomas Werner). Homology modeling in biology and medicine (Roland L. Dunbrack, Jr.). Protein structure prediction (Ralf Zimmer and Thomas Lengauer). Protein-ligand docking in drug design (Matthias Rarey). Modellimg protein-protein and protein-DNA docking (Michael J. E. Sternberg and Gidon Moont). v.2: Applications: Integrating and accessing molecular biology resources (David P. Hansen and Thure Etzold). Bioinformatics support of genome sequencing projects (Xiaoqiu Huang). Analysis of sequence variations (Christopher S. Carlson, Mark J. Rieder and Deborah A. Nickerson). Proteome analysis (Pierre-Alain Binz, Elisabeth Gasteiger, Jean-Charles Sanchez, Amos Bairoch, Denis F. Hochstrasser, Ron D. Appel). Target finding in genomes and proteomes (Stephanie Fuhrman Liang, Xiling Wen and Roland Somogyi). Screening of drug databases (Martin Stahl, Matthias Rarey and Gerhard Klebe). Future trends (Thomas Lengauer).
Download or read book Molecular Modeling on the PC written by Matthew F. Schlecht and published by Wiley-VCH. This book was released on 1998 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to molecular modeling. PC molecular modeling hardware and software. Input and output. Input files formats. The molecular mechanics force field. Applications. Appendices.
