Download or read book Modeling Sensorineural Hearing Loss written by Walt Jesteadt and published by Routledge. This book was released on 2019-01-04 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: A recent study indicates that 20 million people in the United States have significant sensorineural hearing loss. Approximately 95% of those people have partial losses, with varying degrees of residual hearing. These percentages are similar in other developed countries. What changes in the function of the cochlea or inner ear cause such losses? What does the world sound like to the 19 million people with residual hearing? How should we transform sounds to correct for the hearing loss and maximize restoration of normal hearing? Answers to such questions require detailed models of the way that sounds are processed by the nervous system, both for listeners with normal hearing and for those with sensorineural hearing loss. This book contains chapters describing the work of 25 different research groups. A great deal of research in recent years has been aimed at obtaining a better physiological description of the altered processes that cause sensorineural hearing loss and a better understanding of transformations that occur in the perception of those sounds that are sufficiently intense that they can still be heard. Efforts to understand these changes in function have lead to a better understanding of normal function as well. This research has been based on rigorous mathematical models, computer simulations of mechanical and physiological processes, and signal processing simulations of the altered perceptual experience of listeners with sensorineural hearing loss. This book provides examples of all these approaches to modeling sensorineural hearing loss and a summary of the latest research in the field.
Download or read book Psychoacoustics written by Jennifer J. Lentz and published by Plural Publishing. This book was released on 2023-11-27 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychoacoustics: Auditory Perception of Listeners with Normal Hearing and Hearing Loss, Second Edition provides an overview of the field of psychoacoustics, with a primary focus on auditory perception. The book retains its focus on applications of psychoacoustics to clinical audiology, and its modular organization, with each chapter including relevant information around a specific topic. Within each chapter, acoustics, physiology, and perception by adult listeners with normal hearing and those with hearing loss, as they relate to that topic, are presented. The influence of hearing loss on these general auditory abilities is discussed in every chapter. Components of the book also include the role of psychoacoustics in audiological assessment and treatment. The text is ideal for audiology students who intend on having a clinical career and need an understanding of both normal and impaired auditory perception. It is intended to give students sufficient information to understand how the ear achieves auditory perception, what the capabilities of the ear are, and how hearing loss influences that perception. It also provides students with a foundation for further study in the area and to apply psychoacoustic principles to diagnostic audiology and audiological rehabilitation. New to the Second Edition: * 70 new figures to clarify some points and facilitate students’ understanding of the material * New chapter that focuses exclusively on the perception by individuals wearing hearing aids and cochlear implants * New section on the perceptual consequences of sensorineural hearing loss on everyday listening added to each chapter * Revamped chapter on Psychoacoustics and Advanced Clinical Auditory Assessment now solely addresses elements within diagnostic audiology that are based on psychoacoustics, with added content on tinnitus assessment, automated (Békésy) audiometry, retrocochlear and pseudohypacusis evaluation, and the identification of dead regions * Enhanced focus on inclusivity, such as alternative versions of some demonstrations designed to be more accessible to individuals with hearing loss, and a new section on the contributions of women and BIPOC scientists to the field of psychoacoustics Key Features: * Learning objectives and summaries begin and end each chapter to convey the goals of the text and review student comprehension * Each chapter contains exercises designed to develop critical thinking about psychoacoustics * Chapters include the following: introduction, relevant acoustics, important physiological studies, perception by normal-hearing listeners, and perception by listeners who have sensorineural hearing loss * Emphasis on applied learning for more effective and efficient learning of the material Disclaimer: Please note that ancillary content such as lab exercises are not included as published in the original print version of this book.
Download or read book National Strategic Research Plan for Hearing and Hearing Impairment and Voice and Voice Disorders written by and published by . This book was released on 1992 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Auditory Trauma Protection and Repair written by Jochen Schacht and published by Springer Science & Business Media. This book was released on 2008-02-10 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has brought great advances in our understanding of the mechanisms underlying auditory pathologies. This volume presents recent developments in research and their potential translation to the clinical setting. It brings together the basic and clinical sciences very nicely in that while most chapters are written by basic scientists, each topic has a pretty direct clinical application or implication.
Download or read book The Micro Vasculature of the Cochlea written by Mattia Carraro and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis concerns the role of cochlear microvasculature in normal hearing function and in pathological conditions that result in hearing loss. In animal models we have investigated two major types of sensorineural hearing loss where degeneration of the stria vascularis has been implicated, namely presbyacusis and hearing loss associated with cytomegalovirus (CMV) infection. The former eventual affects all aging humans; the latter is a common etiology for congenital hearing loss in infants. The focus of experimental work is on the capillary networks of the cochlea. We chose to use corrosion cast techniques to visualize and quantify capillary vessel parameters. For the small and delicate cochleas of our mouse models, this required extensive technical improvements to corrosion casting methodology. These innovations proved successful. Three experimental animal model studies were made. The first involved analysis, and modeling of strial feeding arterioles in normal subject. The hypothesis posed was that the highly convoluted structure of these vessels acts to dampen cardiovascular pulsations within the cochlea and thereby prevent self-stimulation by such biological noise. The results from this study support the hypothesis. In our murine models of presbyacusis and of CMV infection we correlated loss of auditory thresholds measured with ABR methods, with degenerative changes to cochlear microvasculature. In mice with age-related, high frequency hearing loss, we report significant vascular degeneration of stria vascularis in basal (high frequency) cochlear areas compared to more apical regions. After CMV infection in newborn mice, we observed at 6 weeks a wide range of auditory threshold changes. At 8 weeks post-infection, the cochleas had suffered a wide range of vascular damage. The most vulnerable structure was stria vascularis in the mid-apical cochlear turn. Our novel finding that vascular damage is the primary lesion after CMV infection is consistent with some clinical characteristics of this hearing loss type in infants.
Download or read book Computational Models of the Auditory System written by Ray Meddis and published by Springer Science & Business Media. This book was released on 2010-06-16 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Springer Handbook of Auditory Research presents a series of comprehensive and synthetic reviews of the fundamental topics in modern auditory research. The v- umes are aimed at all individuals with interests in hearing research including advanced graduate students, post-doctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to better understand the fundamental theories and data in fields of hearing that they may not normally follow closely. Each volume presents a particular topic comprehensively, and each serves as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in pe- reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beg- ning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.
Download or read book Scientific Foundations of Audiology written by Anthony T. Cacace and published by Plural Publishing. This book was released on 2016-04-15 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: With advancements across various scientific and medical fields, professionals in audiology are in a unique position to integrate cutting-edge technology with real-world situations. Scientific Foundations of Audiology provides a strong basis and philosophical framework for understanding various domains of hearing science in the context of contemporary developments in genetics, gene expression, bioengineering, neuroimaging, neurochemistry, cochlear and mid-brain implants, associated speech processing and understanding, molecular biology, physics, modeling, medicine, and clinical practice. Key features of this text include: Highly technical information presented in a cohesive and understandable manner (i.e., concepts without complex equations)Discussion of integrating newly developed technology within the clinical practice of audiologyState-of-the-art contributions from a stellar array of international, world-class experts Scientific Foundations of Audiology is geared toward doctoral students in audiology, physics, and engineering; residents in otolaryngology, neurology, neurosurgery, and pediatrics; and those intermediaries between innovation and clinical reality.
Download or read book Sensorineural Hearing Loss written by Mary Jane Collins and published by . This book was released on 1986 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sourcebook of Models for Biomedical Research written by P. Michael Conn and published by Springer Science & Business Media. This book was released on 2008 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.
Download or read book Translational Research in Audiology Neurotology and the Hearing Sciences written by Colleen G. Le Prell and published by Springer. This book was released on 2016-10-26 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Most scientific training programs provide little or no systematic introduction to the issues, challenges, and obstacles that prevent effective research translation, even though these are the key steps that enable high-impact basic science to ultimately result in significant clinical advances that improve patient outcome. This volume will provide an overview of key issues in translation of research from “bedside to bench to bedside”, not only from the perspective of the key funding agencies, but also from the scientists and clinicians who are currently involved in the translational research process. It will attempt to offer insight into real-world experience with intellectual property and technology transfer activities that can help move auditory technologies ahead, as scientists and clinicians typically have little or no formal training in these areas. Translational Research in Audiology and the Hearing Sciences will be aimed at graduate students and postdoctoral investigators, as well as professionals and academics. It is intended to function as a high-profile and up-to-date reference work on Translational Research in the auditory sciences, emphasizing research programs in the traditional areas including drugs and devices, as well as less traditional, still emerging, areas such as sensorineural hearing loss, auditory processing disorder, cochlear implants and hearing aids, and tinnitus therapies.
Download or read book Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics written by Srdjan M Vlajkovic and published by . This book was released on 2021-10-25 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sense of hearing is vulnerable to environmental challenges, such as exposure to noise. More than 1.5 billion people experience some decline in hearing ability during their lifetime, of whom at least 430 million will be affected by disabling hearing loss. If not identified and addressed in a timely way, hearing loss can severely reduce the quality of life at various stages. Some causes of hearing loss can be prevented, for example from occupational or leisure noise. The World Health Organization estimates that more than 1 billion young people put themselves at risk of permanent hearing loss by listening to loud music over long periods of time. Mitigating such risks through public health action is essential to reduce the impact of hearing loss in the community. The etiology of sensorineural hearing loss is complex and multifactorial, arising from congenital and acquired causes. This book highlights the diverse range of approaches to sensorineural hearing loss, from designing new animal models of age-related hearing loss, to the use of microRNAs as biomarkers of cochlear injury and drug repurposing for the therapy of agerelated and noise-induced hearing loss. Further investigation into the underlying molecular mechanisms of sensorineural hearing loss and the integration of the novel drug, cell, and gene therapy strategies into controlled clinical studies will permit significant advances in a field where there are currently many unmet needs.
Download or read book Hearing Loss written by National Research Council and published by National Academies Press. This book was released on 2004-12-17 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans experience some degree of hearing loss. The Social Security Administration (SSA) operates programs that provide cash disability benefits to people with permanent impairments like hearing loss, if they can show that their impairments meet stringent SSA criteria and their earnings are below an SSA threshold. The National Research Council convened an expert committee at the request of the SSA to study the issues related to disability determination for people with hearing loss. This volume is the product of that study. Hearing Loss: Determining Eligibility for Social Security Benefits reviews current knowledge about hearing loss and its measurement and treatment, and provides an evaluation of the strengths and weaknesses of the current processes and criteria. It recommends changes to strengthen the disability determination process and ensure its reliability and fairness. The book addresses criteria for selection of pure tone and speech tests, guidelines for test administration, testing of hearing in noise, special issues related to testing children, and the difficulty of predicting work capacity from clinical hearing test results. It should be useful to audiologists, otolaryngologists, disability advocates, and others who are concerned with people who have hearing loss.
Download or read book The Contribution of High Frequencies to Speech Recognition in Sensorineural Hearing Loss written by Nathan E. Amos and published by . This book was released on 2001 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Investigation of Sensorineural Hearing Impairment Using a Center Clipping Model written by Erik Ian Gilbert and published by . This book was released on 1984 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Aging Auditory System written by Sandra Gordon-Salant and published by Springer Science & Business Media. This book was released on 2009-12-02 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together noted scientists who study presbycusis from the perspective of complementary disciplines, for a review of the current state of knowledge on the aging auditory system. Age-related hearing loss (ARHL) is one of the top three most common chronic health conditions affecting individuals aged 65 years and older. The high prevalence of age-related hearing loss compels audiologists, otolaryngologists, and auditory neuroscientists alike to understand the neural, genetic and molecular mechanisms underlying this disorder. A comprehensive understanding of these factors is needed so that effective prevention, intervention, and rehabilitative strategies can be developed to ameliorate the myriad of behavioral manifestations.
Download or read book Simulation of the Effects of Sensorineural Hearing Loss written by Isaac John Graf and published by . This book was released on 1997 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book written by מאיר (הלוי, א.ב.ד. בק.ק. סטבניץ ואפטא) and published by . This book was released on 1947* with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:
