Download or read book Modeling Infectious Disease Parameters Based on Serological and Social Contact Data written by Niel Hens and published by Springer Science & Business Media. This book was released on 2012-10-24 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical epidemiology of infectious diseases usually involves describing the flow of individuals between mutually exclusive infection states. One of the key parameters describing the transition from the susceptible to the infected class is the hazard of infection, often referred to as the force of infection. The force of infection reflects the degree of contact with potential for transmission between infected and susceptible individuals. The mathematical relation between the force of infection and effective contact patterns is generally assumed to be subjected to the mass action principle, which yields the necessary information to estimate the basic reproduction number, another key parameter in infectious disease epidemiology. It is within this context that the Center for Statistics (CenStat, I-Biostat, Hasselt University) and the Centre for the Evaluation of Vaccination and the Centre for Health Economic Research and Modelling Infectious Diseases (CEV, CHERMID, Vaccine and Infectious Disease Institute, University of Antwerp) have collaborated over the past 15 years. This book demonstrates the past and current research activities of these institutes and can be considered to be a milestone in this collaboration. This book is focused on the application of modern statistical methods and models to estimate infectious disease parameters. We want to provide the readers with software guidance, such as R packages, and with data, as far as they can be made publicly available.
Download or read book Handbook of Infectious Disease Data Analysis written by Leonhard Held and published by CRC Press. This book was released on 2019-11-07 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen an explosion in new kinds of data on infectious diseases, including data on social contacts, whole genome sequences of pathogens, biomarkers for susceptibility to infection, serological panel data, and surveillance data. The Handbook of Infectious Disease Data Analysis provides an overview of many key statistical methods that have been developed in response to such new data streams and the associated ability to address key scientific and epidemiological questions. A unique feature of the Handbook is the wide range of topics covered. Key features Contributors include many leading researchers in the field Divided into four main sections: Basic concepts, Analysis of Outbreak Data, Analysis of Seroprevalence Data, Analysis of Surveillance Data Numerous case studies and examples throughout Provides both introductory material and key reference material
Download or read book Modeling Infectious Diseases in Humans and Animals written by Matt J. Keeling and published by Princeton University Press. This book was released on 2011-09-19 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: For epidemiologists, evolutionary biologists, and health-care professionals, real-time and predictive modeling of infectious disease is of growing importance. This book provides a timely and comprehensive introduction to the modeling of infectious diseases in humans and animals, focusing on recent developments as well as more traditional approaches. Matt Keeling and Pejman Rohani move from modeling with simple differential equations to more recent, complex models, where spatial structure, seasonal "forcing," or stochasticity influence the dynamics, and where computer simulation needs to be used to generate theory. In each of the eight chapters, they deal with a specific modeling approach or set of techniques designed to capture a particular biological factor. They illustrate the methodology used with examples from recent research literature on human and infectious disease modeling, showing how such techniques can be used in practice. Diseases considered include BSE, foot-and-mouth, HIV, measles, rubella, smallpox, and West Nile virus, among others. Particular attention is given throughout the book to the development of practical models, useful both as predictive tools and as a means to understand fundamental epidemiological processes. To emphasize this approach, the last chapter is dedicated to modeling and understanding the control of diseases through vaccination, quarantine, or culling. Comprehensive, practical introduction to infectious disease modeling Builds from simple to complex predictive models Models and methodology fully supported by examples drawn from research literature Practical models aid students' understanding of fundamental epidemiological processes For many of the models presented, the authors provide accompanying programs written in Java, C, Fortran, and MATLAB In-depth treatment of role of modeling in understanding disease control
Download or read book Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases written by Dongmei Chen and published by John Wiley & Sons. This book was released on 2014-12-08 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features modern research and methodology on the spread of infectious diseases and showcases a broad range of multi-disciplinary and state-of-the-art techniques on geo-simulation, geo-visualization, remote sensing, metapopulation modeling, cloud computing, and pattern analysis Given the ongoing risk of infectious diseases worldwide, it is crucial to develop appropriate analysis methods, models, and tools to assess and predict the spread of disease and evaluate the risk. Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features mathematical and spatial modeling approaches that integrate applications from various fields such as geo-computation and simulation, spatial analytics, mathematics, statistics, epidemiology, and health policy. In addition, the book captures the latest advances in the use of geographic information system (GIS), global positioning system (GPS), and other location-based technologies in the spatial and temporal study of infectious diseases. Highlighting the current practices and methodology via various infectious disease studies, Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features: Approaches to better use infectious disease data collected from various sources for analysis and modeling purposes Examples of disease spreading dynamics, including West Nile virus, bird flu, Lyme disease, pandemic influenza (H1N1), and schistosomiasis Modern techniques such as Smartphone use in spatio-temporal usage data, cloud computing-enabled cluster detection, and communicable disease geo-simulation based on human mobility An overview of different mathematical, statistical, spatial modeling, and geo-simulation techniques Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases is an excellent resource for researchers and scientists who use, manage, or analyze infectious disease data, need to learn various traditional and advanced analytical methods and modeling techniques, and become aware of different issues and challenges related to infectious disease modeling and simulation. The book is also a useful textbook and/or supplement for upper-undergraduate and graduate-level courses in bioinformatics, biostatistics, public health and policy, and epidemiology.
Download or read book An Introduction to Infectious Disease Modelling written by Emilia Vynnycky and published by Oxford University Press. This book was released on 2010-05-13 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical models are increasingly used to guide public health policy decisions and explore questions in infectious disease control. Written for readers without advanced mathematical skills, this book provides an introduction to this area.
Download or read book Modeling and Dynamics of Infectious Diseases written by Zhien Ma and published by World Scientific. This book was released on 2009 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a systematic introduction to the fundamental methods and techniques and the frontiers of ? along with many new ideas and results on ? infectious disease modeling, parameter estimation and transmission dynamics. It provides complementary approaches, from deterministic to statistical to network modeling; and it seeks viewpoints of the same issues from different angles, from mathematical modeling to statistical analysis to computer simulations and finally to concrete applications.
Download or read book Charting the Next Pandemic written by Ana Pastore y Piontti and published by Springer. This book was released on 2018-11-07 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to the computational and complex systems modeling of the global spreading of infectious diseases. The latest developments in the area of contagion processes modeling are discussed, and readers are exposed to real world examples of data-model integration impacting the decision-making process. Recent advances in computational science and the increasing availability of real-world data are making it possible to develop realistic scenarios and real-time forecasts of the global spreading of emerging health threats. The first part of the book guides the reader through sophisticated complex systems modeling techniques with a non-technical and visual approach, explaining and illustrating the construction of the modern framework used to project the spread of pandemics and epidemics. Models can be used to transform data to knowledge that is intuitively communicated by powerful infographics and for this reason, the second part of the book focuses on a set of charts that illustrate possible scenarios of future pandemics. The visual atlas contained allows the reader to identify commonalities and patterns in emerging health threats, as well as explore the wide range of models and data that can be used by policy makers to anticipate trends, evaluate risks and eventually manage future events. Charting the Next Pandemic puts the reader in the position to explore different pandemic scenarios and to understand the potential impact of available containment and prevention strategies. This book emphasizes the importance of a global perspective in the assessment of emerging health threats and captures the possible evolution of the next pandemic, while at the same time providing the intelligence needed to fight it. The text will appeal to a wide range of audiences with diverse technical backgrounds.
Download or read book Infectious Disease Modeling written by Xinzhi Liu and published by Springer. This book was released on 2017-02-25 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents infectious diseases modeled mathematically, taking seasonality and changes in population behavior into account, using a switched and hybrid systems framework. The scope of coverage includes background on mathematical epidemiology, including classical formulations and results; a motivation for seasonal effects and changes in population behavior, an investigation into term-time forced epidemic models with switching parameters, and a detailed account of several different control strategies. The main goal is to study these models theoretically and to establish conditions under which eradication or persistence of the disease is guaranteed. In doing so, the long-term behavior of the models is determined through mathematical techniques from switched systems theory. Numerical simulations are also given to augment and illustrate the theoretical results and to help study the efficacy of the control schemes.
Download or read book The Geographic Spread of Infectious Diseases written by Lisa Sattenspiel and published by Princeton University Press. This book was released on 2009-07-26 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1918-19 influenza epidemic killed more than fifty million people worldwide. The SARS epidemic of 2002-3, by comparison, killed fewer than a thousand. The success in containing the spread of SARS was due largely to the rapid global response of public health authorities, which was aided by insights resulting from mathematical models. Models enabled authorities to better understand how the disease spread and to assess the relative effectiveness of different control strategies. In this book, Lisa Sattenspiel and Alun Lloyd provide a comprehensive introduction to mathematical models in epidemiology and show how they can be used to predict and control the geographic spread of major infectious diseases. Key concepts in infectious disease modeling are explained, readers are guided from simple mathematical models to more complex ones, and the strengths and weaknesses of these models are explored. The book highlights the breadth of techniques available to modelers today, such as population-based and individual-based models, and covers specific applications as well. Sattenspiel and Lloyd examine the powerful mathematical models that health authorities have developed to understand the spatial distribution and geographic spread of influenza, measles, foot-and-mouth disease, and SARS. Analytic methods geographers use to study human infectious diseases and the dynamics of epidemics are also discussed. A must-read for students, researchers, and practitioners, no other book provides such an accessible introduction to this exciting and fast-evolving field.
Download or read book Attribute assignment to a synthetic population in support of agent based disease modeling written by James C. Cajka and published by RTI Press. This book was released on 2010-09-27 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: Communicable-disease transmission models are useful for the testing of prevention and intervention strategies. Agent-based models (ABMs) represent a new and important class of the many types of disease transmission models in use. Agent-based disease models benefit from their ability to assign disease transmission probabilities based on characteristics shared by individual agents. These shared characteristics allow ABMs to apply transmission probabilities when agents come together in geographic space. Modeling these types of social interactions requires data, and the results of the model largely depend on the quality of these input data. We initially generated a synthetic population for the United States, in support of the Models of Infectious Disease Agent Study. Subsequently, we created shared characteristics to use in ABMs. The specific goals for this task were to assign the appropriately aged populations to schools, workplaces, and public transit. Each goal presented its own challenges and problems; therefore, we used different techniques to create each type of shared characteristic. These shared characteristics have allowed disease models to more realistically predict the spread of disease, both spatially and temporally.
Download or read book Modern Infectious Disease Epidemiology written by Alexander Krämer and published by Springer Science & Business Media. This book was released on 2010-01-23 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardly a day goes by without news headlines concerning infectious disease threats. Currently the spectre of a pandemic of influenza A|H1N1 is raising its head, and heated debates are taking place about the pro’s and con’s of vaccinating young girls against human papilloma virus. For an evidence-based and responsible communication of infectious disease topics to avoid misunderstandings and overreaction of the public, we need solid scientific knowledge and an understanding of all aspects of infectious diseases and their control. The aim of our book is to present the reader with the general picture and the main ideas of the subject. The book introduces the reader to methodological aspects of epidemiology that are specific for infectious diseases and provides insight into the epidemiology of some classes of infectious diseases characterized by their main modes of transmission. This choice of topics bridges the gap between scientific research on the clinical, biological, mathematical, social and economic aspects of infectious diseases and their applications in public health. The book will help the reader to understand the impact of infectious diseases on modern society and the instruments that policy makers have at their disposal to deal with these challenges. It is written for students of the health sciences, both of curative medicine and public health, and for experts that are active in these and related domains, and it may be of interest for the educated layman since the technical level is kept relatively low.
Download or read book Mathematical Modeling Approach To Infectious Diseases A Cross Diffusion Pde Models For Epidemiology written by Schiesser William E and published by World Scientific. This book was released on 2018-06-27 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mathematical Tools for Understanding Infectious Disease Dynamics written by Odo Diekmann and published by Princeton University Press. This book was released on 2012-11-18 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical modeling is critical to our understanding of how infectious diseases spread at the individual and population levels. This book gives readers the necessary skills to correctly formulate and analyze mathematical models in infectious disease epidemiology, and is the first treatment of the subject to integrate deterministic and stochastic models and methods. Mathematical Tools for Understanding Infectious Disease Dynamics fully explains how to translate biological assumptions into mathematics to construct useful and consistent models, and how to use the biological interpretation and mathematical reasoning to analyze these models. It shows how to relate models to data through statistical inference, and how to gain important insights into infectious disease dynamics by translating mathematical results back to biology. This comprehensive and accessible book also features numerous detailed exercises throughout; full elaborations to all exercises are provided. Covers the latest research in mathematical modeling of infectious disease epidemiology Integrates deterministic and stochastic approaches Teaches skills in model construction, analysis, inference, and interpretation Features numerous exercises and their detailed elaborations Motivated by real-world applications throughout
Download or read book Models for Infectious Human Diseases written by Valerie Isham and published by Cambridge University Press. This book was released on 1996-03-29 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious disease accounts for more death and disability globally than either non-infectious disease or injury. This book contains a breadth of different quantitative approaches to understanding the patterns of infectious diseases in populations, and the design of control strategies to lessen their effect. The contributors bring a great variety of mathematical expertise (including deterministic and stochastic modelling and statistical data analysis) and involvement in a wide range of applied fields across the spectrum of biological, medical and social sciences. The aim is to increase interaction between specialities by describing research on many of the infectious diseases that affect humans, including both viral diseases like measles and AIDS and tropical parasitic infections. The papers are divided into groups dealing with problems relating to transmissible diseases, vaccination strategies, the consequences of treatment interventions, the dynamics of immunity, heterogeneity of populations, and prediction.
Download or read book Quantitative Methods for Investigating Infectious Disease Outbreaks written by Ping Yan and published by Springer. This book was released on 2019-08-16 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a systematic treatment of the mathematical underpinnings of work in the theory of outbreak dynamics and their control, covering balanced perspectives between theory and practice including new material on contemporary topics in the field of infectious disease modelling. Specifically, it presents a unified mathematical framework linked to the distribution theory of non-negative random variables; the many examples used in the text, are introduced and discussed in light of theoretical perspectives. The book is organized into 9 chapters: The first motivates the presentation of the material on subsequent chapters; Chapter 2-3 provides a review of basic concepts of probability and statistical models for the distributions of continuous lifetime data and the distributions of random counts and counting processes, which are linked to phenomenological models. Chapters 4 focuses on dynamic behaviors of a disease outbreak during the initial phase while Chapters 5-6 broadly cover compartment models to investigate the consequences of epidemics as the outbreak moves beyond the initial phase. Chapter 7 provides a transition between mostly theoretical topics in earlier chapters and Chapters 8 and 9 where the focus is on the data generating processes and statistical issues of fitting models to data as well as specific mathematical epidemic modeling applications, respectively. This book is aimed at a wide audience ranging from graduate students to established scientists from quantitatively-oriented fields of epidemiology, mathematics and statistics. The numerous examples and illustrations make understanding of the mathematics of disease transmission and control accessible. Furthermore, the examples and exercises, make the book suitable for motivated students in applied mathematics, either through a lecture course, or through self-study. This text could be used in graduate schools or special summer schools covering research problems in mathematical biology.
Download or read book Mathematical Epidemiology written by Fred Brauer and published by Springer Science & Business Media. This book was released on 2008-04-30 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on lecture notes of two summer schools with a mixed audience from mathematical sciences, epidemiology and public health, this volume offers a comprehensive introduction to basic ideas and techniques in modeling infectious diseases, for the comparison of strategies to plan for an anticipated epidemic or pandemic, and to deal with a disease outbreak in real time. It covers detailed case studies for diseases including pandemic influenza, West Nile virus, and childhood diseases. Models for other diseases including Severe Acute Respiratory Syndrome, fox rabies, and sexually transmitted infections are included as applications. Its chapters are coherent and complementary independent units. In order to accustom students to look at the current literature and to experience different perspectives, no attempt has been made to achieve united writing style or unified notation. Notes on some mathematical background (calculus, matrix algebra, differential equations, and probability) have been prepared and may be downloaded at the web site of the Centre for Disease Modeling (www.cdm.yorku.ca).
Download or read book Mathematical Epidemiology of Infectious Diseases written by O. Diekmann and published by John Wiley & Sons. This book was released on 2000-04-07 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Epidemiology of Infectious Diseases Model Building, Analysis and Interpretation O. Diekmann University of Utrecht, The Netherlands J. A. P. Heesterbeek Centre for Biometry Wageningen, The Netherlands The mathematical modelling of epidemics in populations is a vast and important area of study. It is about translating biological assumptions into mathematics, about mathematical analysis aided by interpretation and about obtaining insight into epidemic phenomena when translating mathematical results back into population biology. Model assumptions are formulated in terms of, usually stochastic, behaviour of individuals and then the resulting phenomena, at the population level, are unravelled. Conceptual clarity is attained, assumptions are stated clearly, hidden working hypotheses are attained and mechanistic links between different observables are exposed. Features: * Model construction, analysis and interpretation receive detailed attention * Uniquely covers both deterministic and stochastic viewpoints * Examples of applications given throughout * Extensive coverage of the latest research into the mathematical modelling of epidemics of infectious diseases * Provides a solid foundation of modelling skills The reader will learn to translate, model, analyse and interpret, with the help of the numerous exercises. In literally working through this text, the reader acquires modelling skills that are also valuable outside of epidemiology, certainly within population dynamics, but even beyond that. In addition, the reader receives training in mathematical argumentation. The text is aimed at applied mathematicians with an interest in population biology and epidemiology, at theoretical biologists and epidemiologists. Previous exposure to epidemic concepts is not required, as all background information is given. The book is primarily aimed at self-study and ideally suited for small discussion groups, or for use as a course text.
