Download or read book Antimalarial Natural Products written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2022-01-02 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature’s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends by identifying ten natural products with development potential as clinical antimalarial agents.

Download or read book Proceedings of the International Congress of Mathematicians 2010 icm 2010 in 4 Volumes Vol I Plenary Lectures and Ceremonies Vols Ii iv Invited Lectures written by and published by World Scientific. This book was released on 2011 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Crisis in the Red Zone written by Richard Preston and published by Random House. This book was released on 2019-07-23 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • An urgent wake-up call about the future of emerging viruses and a gripping account of the doctors and scientists fighting to protect us, told through the story of the deadly 2013–2014 Ebola epidemic “Crisis in the Red Zone reads like a thriller. That the story it tells is all true makes it all more terrifying.”—Elizabeth Kolbert, Pulitzer Prize–winning author of The Sixth Extinction From the #1 bestselling author of The Hot Zone, now a National Geographic original miniseries . . . This time, Ebola started with a two-year-old child who likely had contact with a wild creature and whose entire family quickly fell ill and died. The ensuing global drama activated health professionals in North America, Europe, and Africa in a desperate race against time to contain the viral wildfire. By the end—as the virus mutated into its deadliest form, and spread farther and faster than ever before—30,000 people would be infected, and the dead would be spread across eight countries on three continents. In this taut and suspenseful medical drama, Richard Preston deeply chronicles the pandemic, in which we saw for the first time the specter of Ebola jumping continents, crossing the Atlantic, and infecting people in America. Rich in characters and conflict—physical, emotional, and ethical—Crisis in the Red Zone is an immersion in one of the great public health calamities of our time. Preston writes of doctors and nurses in the field putting their own lives on the line, of government bureaucrats and NGO administrators moving, often fitfully, to try to contain the outbreak, and of pharmaceutical companies racing to develop drugs to combat the virus. He also explores the charged ethical dilemma over who should and did receive the rare doses of an experimental treatment when they became available at the peak of the disaster. Crisis in the Red Zone makes clear that the outbreak of 2013–2014 is a harbinger of further, more severe outbreaks, and of emerging viruses heretofore unimagined—in any country, on any continent. In our ever more interconnected world, with roads and towns cut deep into the jungles of equatorial Africa, viruses both familiar and undiscovered are being unleashed into more densely populated areas than ever before. The more we discover about the virosphere, the more we realize its deadly potential. Crisis in the Red Zone is an exquisitely timely book, a stark warning of viral outbreaks to come.

Download or read book Citizen Subject written by Étienne Balibar and published by Fordham Univ Press. This book was released on 2016-11-01 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: What can the universals of political philosophy offer to those who experience "the living paradox of an inegalitarian construction of egalitarian citizenship"? Citizen Subject is the summation of Étienne Balibar’s career-long project to think the necessary and necessarily antagonistic relation between the categories of citizen and subject. In this magnum opus, the question of modernity is framed anew with special attention to the self-enunciation of the subject (in Descartes, Locke, Rousseau, and Derrida), the constitution of the community as “we” (in Hegel, Marx, and Tolstoy), and the aporia of the judgment of self and others (in Foucualt, Freud, Kelsen, and Blanchot). After the “humanist controversy” that preoccupied twentieth-century philosophy, Citizen Subject proposes foundations for philosophical anthropology today, in terms of two contrary movements: the becoming-citizen of the subject and the becoming-subject of the citizen. The citizen-subject who is constituted in the claim to a “right to have rights” (Arendt) cannot exist without an underside that contests and defies it. He—or she, because Balibar is concerned throughout this volume with questions of sexual difference—figures not only the social relation but also the discontent or the uneasiness at the heart of this relation. The human can be instituted only if it betrays itself by upholding “anthropological differences” that impose normality and identity as conditions of belonging to the community. The violence of “civil” bourgeois universality, Balibar argues, is greater (and less legitimate, therefore less stable) than that of theological or cosmological universality. Right is thus founded on insubordination, and emancipation derives its force from otherness. Ultimately, Citizen Subject offers a revolutionary rewriting of the dialectic of universality and differences in the bourgeois epoch, revealing in the relationship between the common and the universal a political gap at the heart of the universal itself.

Download or read book The Lost City of the Monkey God written by Douglas Preston and published by Grand Central Publishing. This book was released on 2017-01-03 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 New York Times and Wall Street Journal bestseller, named one of the best books of the year by The Boston Globe and National Geographic: acclaimed journalist Douglas Preston takes readers on a true adventure deep into the Honduran rainforest in this riveting narrative about the discovery of a lost civilization -- culminating in a stunning medical mystery. Since the days of conquistador Hernán Cortés, rumors have circulated about a lost city of immense wealth hidden somewhere in the Honduran interior, called the White City or the Lost City of the Monkey God. Indigenous tribes speak of ancestors who fled there to escape the Spanish invaders, and they warn that anyone who enters this sacred city will fall ill and die. In 1940, swashbuckling journalist Theodore Morde returned from the rainforest with hundreds of artifacts and an electrifying story of having found the Lost City of the Monkey God-but then committed suicide without revealing its location. Three quarters of a century later, bestselling author Doug Preston joined a team of scientists on a groundbreaking new quest. In 2012 he climbed aboard a rickety, single-engine plane carrying the machine that would change everything: lidar, a highly advanced, classified technology that could map the terrain under the densest rainforest canopy. In an unexplored valley ringed by steep mountains, that flight revealed the unmistakable image of a sprawling metropolis, tantalizing evidence of not just an undiscovered city but an enigmatic, lost civilization. Venturing into this raw, treacherous, but breathtakingly beautiful wilderness to confirm the discovery, Preston and the team battled torrential rains, quickmud, disease-carrying insects, jaguars, and deadly snakes. But it wasn't until they returned that tragedy struck: Preston and others found they had contracted in the ruins a horrifying, sometimes lethal-and incurable-disease. Suspenseful and shocking, filled with colorful history, hair-raising adventure, and dramatic twists of fortune, THE LOST CITY OF THE MONKEY GOD is the absolutely true, eyewitness account of one of the great discoveries of the twenty-first century.

Download or read book Camera Traps in Animal Ecology written by Allan F. O'Connell and published by Springer Science & Business Media. This book was released on 2010-10-05 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Remote photography and infrared sensors are widely used in the sampling of wildlife populations worldwide, especially for cryptic or elusive species. Guiding the practitioner through the entire process of using camera traps, this book is the first to compile state-of-the-art sampling techniques for the purpose of conducting high-quality science or effective management. Chapters on the evaluation of equipment, field sampling designs, and data analysis methods provide a coherent framework for making inferences about the abundance, species richness, and occupancy of sampled animals. The volume introduces new models that will revolutionize use of camera data to estimate population density, such as the newly developed spatial capture–recapture models. It also includes richly detailed case studies of camera trap work on some of the world’s most charismatic, elusive, and endangered wildlife species. Indispensible to wildlife conservationists, ecologists, biologists, and conservation agencies around the world, the text provides a thorough review of the subject as well as a forecast for the use of remote photography in natural resource conservation over the next few decades.

Download or read book Players and Pawns written by Gary Alan Fine and published by University of Chicago Press. This book was released on 2015-08-06 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: A chess match seems as solitary an endeavor as there is in sports: two minds, on their own, in fierce opposition. In contrast, Gary Alan Fine argues that chess is a social duet: two players in silent dialogue who always take each other into account in their play. Surrounding that one-on-one contest is a community life that can be nearly as dramatic and intense as the across-the-board confrontation. Fine has spent years immersed in the communities of amateur and professional chess players, and with Players and Pawns he takes readers deep inside them, revealing a complex, brilliant, feisty world of commitment and conflict. Within their community, chess players find both support and challenges, all amid a shared interest in and love of the long-standing traditions of the game, traditions that help chess players build a communal identity. Full of idiosyncratic characters and dramatic gameplay, Players and Pawns is a celebration of the fascinating world of serious chess.

Download or read book Existence in Black written by Lewis Ricardo Gordon and published by Psychology Press. This book was released on 1997 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of essays and reviews represents the most significant and comprehensive writing on Shakespeare's A Comedy of Errors. Miola's edited work also features a comprehensive critical history, coupled with a full bibliography and photographs of major productions of the play from around the world. In the collection, there are five previously unpublished essays. The topics covered in these new essays are women in the play, the play's debt to contemporary theater, its critical and performance histories in Germany and Japan, the metrical variety of the play, and the distinctly modern perspective on the play as containing dark and disturbing elements. To compliment these new essays, the collection features significant scholarship and commentary on The Comedy of Errors that is published in obscure and difficulty accessible journals, newspapers, and other sources. This collection brings together these essays for the first time.

Download or read book Border Matters written by José David Saldívar and published by Univ of California Press. This book was released on 2023-04-28 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Border Matters locates the study of Chicano culture in a broad social context. José Saldívar examines issues of representation and expression in a diverse, exciting assortment of texts—corridos, novels, poems, short stories, punk and hip-hop music, ethnography, paintings, performance, art, and essays. Saldívar provides a sophisticated model for a new kind of U.S. cultural studies, one that challenges the homogeneity of U.S. nationalism and popular culture by foregrounding the contemporary experiences and historical circumstances facing Chicanos and Chicanas. This intellectually adventurous, politically engaged study applies borderlands and diaspora theory to Chicano cultural practices in a way that permanently changes our understanding of both the Chicano experience and the meaning of cultural theory. Defying national (and nationalistic) paradigms of culture, Saldívar argues that the culture of the borderlands is trans-national, constituting a social space in which new relations, hybrid cultures, and multi-voiced aesthetics are negotiated. Saldívar's critical readings treat culture as a social force and reveal the presence of social contexts within cultural texts. Border Matters maps out a new terrain for the study of culture, reshaping the way we understand migration, national identity, and intellectual inquiry itself.

Download or read book Lyra Minima written by Stephen Reckert and published by . This book was released on 1970 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Conservation Handbook written by William J. Sutherland and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbooks on the principles of conservation biology abound. Yet, how does one put this theoretical knowledge into practice? The aim of The Conservation Handbook is to provide clear guidance on the implementation of conservation techniques. The wide range of methods described include those for ecological research, monitoring, planning, education, habitat management and combining conservation with development. Nineteen case studies illustrate how the methods have been applied. The book will be of interest to conservation biology students and practicing conservationists worldwide. For each copy of the book sold, another copy will be sent free to a practicing conservationist outside Western Europe, North America, Australia, New Zealand and Japan. Foreword by E. O. Wilson. Concise, practical guide packed full of ideas, methods and advice. Provides solutions for the main conservation problems most commonly encountered. 18 global case studies illustrate the application of techniques. The Conservation Handbook Donations Project this book is being sent free to those practising conservationists outside Western Europe, North America, Australia, New Zealand and Japan who are otherwise unlikely to obtain a copy. These copies are provided at cost price by Blackwell Science, the publisher, and paid for with the author''s royalties. Each book sold means another one will be donated.

Download or read book The Washington Manual of Medical Therapeutics written by Charles F. Carey and published by . This book was released on 1998 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established for over 50 years as the "Bible" of the medical ward, the Washington Manual is now in its Twenty-Ninth Edition. This edition has been updated up to the moment of publishing to put recent and accurate dosages and patient management recommendations at your fingertips. It also features a new chapter on critical care and medical emergencies. The book's handy pocket size, easy-to-use outline format, bold headings, plentiful charts and tables, and extensive index ensure fast access to specific information.

Download or read book Introduction to Documentary Second Edition written by Bill Nichols and published by Indiana University Press. This book was released on 2010-12-07 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition of Bill Nichols’s bestselling text provides an up-to-date introduction to the most important issues in documentary history and criticism. Designed for students in any field that makes use of visual evidence and persuasive strategies, Introduction to Documentary identifies the distinguishing qualities of documentary and teaches the viewer how to read documentary film. Each chapter takes up a discrete question, from "How did documentary filmmaking get started?" to "Why are ethical issues central to documentary filmmaking?" Carefully revised to take account of new work and trends, this volume includes information on more than 100 documentaries released since the first edition, an expanded treatment of the six documentary modes, new still images, and a greatly expanded list of distributors.

Download or read book Neotropical Wildlife Use and Conservation written by John G. Robinson and published by . This book was released on 1991 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Framing the issues; Subsistence hunting; Market hunting and collecting; Wildlife farming and ranching; Sport hunting; Commercial Uses; The future.

Download or read book The Spanish Arcadia written by Javier Irigoyen-Garcia and published by University of Toronto Press. This book was released on 2013-12-31 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Spanish Arcadia analyzes the figure of the shepherd in the sixteenth- and seventeenth-century Spanish imaginary, exploring its centrality to the discourses on racial, cultural, and religious identity. Drawing on a wide range of documents, including theological polemics on blood purity, political treatises, manuals on animal husbandry, historiography, paintings, epic poems, and Spanish ballads, Javier Irigoyen-García argues that the figure of the shepherd takes on extraordinary importance in the reshaping of early modern Spanish identity. The Spanish Arcadia contextualizes pastoral romances within a broader framework and assesses how they inform other cultural manifestations. In doing so, Irigoyen-García provides incisive new ideas about the social and ethnocentric uses of the genre, as well as its interrelation with ideas of race, animal husbandry, and nation building in early modern Spain.

Download or read book The Apollonian Clockwork written by Louis Andriessen and published by Amsterdam University Press. This book was released on 2006 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: The one book about Stravinsky Stravinsky would have liked. Richard Taruskin.

Download or read book Obscenity and the Law written by Norman St. John-Stevas and published by London : Secker & Warburg. This book was released on 1956 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: