Download or read book Microsomes Drug Oxidations and Chemical Carcinogenesis V2 written by Minor Coon and published by Elsevier. This book was released on 2012-12-02 with total page 655 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microsomes, Drug Oxidations, and Chemical Carcinogenesis, Volume II, documents the proceedings of the 4th International Symposium on Microsomes and Drug Oxidations held in Ann Arbor, July 1979. The symposium reviewed progress in the understanding of scientific and biomedical problems from a biochemical, biophysical, pharmacological, and toxicological perspective. Volume I contained 117 contributions made by researchers at the symposium, which were organized into three sections (Sections I-III). This second volume contains 122 contributions, divided into four sections (Sections IV-VII). The papers on Section IV examine the metabolic fate of oxygenated compounds. Section V provides studies on microsomal enzymes and lipid metabolism. Section VI includes papers on microsomal enzymes and toxicity of foreign compounds. Section VII covers microsomal enzymes and chemical mutagenesis and carcinogenesis. This book seeks to aid future progress in understanding the complexities of metabolic transformations by these versatile enzyme systems that act on physiologically important lipids as well as on a wide array of foreign substances, including drugs, anesthetics, industrial chemicals, food additives, pesticides, carcinogens, and nonnutrient dietary chemicals.
Download or read book Microsomes Drug Oxidations and Chemical Carcinogenesis Vol 2 written by and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microsomes Drug Oxidations and Chemical Carcinogenesis written by MJ Coon (Ed) and published by . This book was released on 1980 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microsomes Drug Oxidations and Chemical Carcinogenesis V1 written by Minor Coon and published by Elsevier. This book was released on 2012-12-02 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microsomes, Drug Oxidations, and Chemical Carcinogenesis, Volume I, documents the proceedings of the 4th International Symposium on Microsomes and Drug Oxidations held in Ann Arbor, July 1979. The symposium reviewed progress in the understanding of scientific and biomedical problems from a biochemical, biophysical, pharmacological, and toxicological perspective. The book contains 117 contributions made by researchers at the symposium, which are organized into three sections. The papers in Section I focus on the chemical and physical characteristics of cytochrome P-450. Section II examines the mechanisms of action of cytochrome P-450 and related enzymes. The studies in Section III deal with the influence of membrane structure and protein synthesis on electron transfer components. This book seeks to aid future progress in understanding the complexities of metabolic transformations by these versatile enzyme systems that act on physiologically important lipids as well as on a wide array of foreign substances, including drugs, anesthetics, industrial chemicals, food additives, pesticides, carcinogens, and nonnutrient dietary chemicals.
Download or read book Microsomes Drug Oxidations and Chemical Carcinogenesis V1 written by Minor Coon and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Microsomes, Drug Oxidations and Chemical Carcinogenesis V1 ...
Download or read book Microsomes Drug Oxidations and Chemical Carcinogenesis written by AH Conney (Ed) and published by . This book was released on 1980 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microsomes Drug Oxidations Ad Chemical Carcinogenesis written by and published by . This book was released on 1980 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microsomes Drug Oxidations and Chemical Carcinogenesis written by Symposium on Microsomes and Drug Oxidations and published by . This book was released on 1980 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microsomes Drug Oxidations and Chemical Carcinogenesis written by M J. Coon and published by . This book was released on 1980 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microsomes drug oxidations and chemical carcinogenesis 4th International symposium on microsomes and drug oxidations held at Ann Arbor Michigan July 16 1979 2 written by Minor Jesser Coon and published by . This book was released on 1980 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microsomes Drug Oxidations and Chemical Carcinogenesis written by International Symposium on Microsomes and Drug Oxidations and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microsomes and Drug Oxidations written by Volker Ullrich and published by Pergamon. This book was released on 1977 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microsomes and Drug Oxidations is a record of the proceedings of the Third International Symposium on Microsomes and Drug Oxidations, held in Berlin, Germany in July 1976. The compendium provides an overview of knowledge on the oxidative metabolism of drugs, carcinogens, and various other environmental chemicals. Topics discussed include lipid structure of liver microsomal membranes; interactions between cytochrome p-450 and nadphcytochrome p-450 reductase in the microsomal membrane; impact of drug monoxygenases in clinical pharmacology; and the manner in which oxygen participates in mixed-fun ...
Download or read book Microsomes Drug Oxidations and Chemical Carcinogenesis written by Minor Jesser Coon and published by . This book was released on 1980 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microsomes, Drug Oxidations and Chemical Carcinogenesis V2 ...
Download or read book Nutritional Toxicology Volume 2 written by John N. Hathcock and published by Elsevier. This book was released on 2013-06-11 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutritional Toxicology, Volume II, discusses the various interactions between nutritional phenomena and toxicologic processes. It addresses particular subjects that have become substantially more important through the development of new knowledge, significant increases in knowledge, or increased awareness of potential effects on human health and well-being. The implications of such knowledge have impact on basic research, toxicity testing, public health, food, and agriculture programs, and food safety regulation. The book begins with a review of the role and importance of macro- and micronutrients on detoxification processes of foreign compounds after absorption. This is followed by separate chapters on mixed-function oxidation in the liver; the metabolic and nutritional effects of ethanol; the effects of malnutrition on drug metabolism; interaction of nutrient intake with DNA and chromatin; and how such interactions may affect the process of toxicogenesis in the nucleus. Subsequent chapters cover mutagens in cooked foods; food sensitivities; anatomical, cardiovascular, and behavioral effects of dietary caffeine; the toxicology of dietary tin, aluminum, and selenium; and the toxicology of pesticides in foods.
Download or read book Microsomes and Drug Oxidations written by A. R. Boobis and published by Taylor & Francis Group. This book was released on 1985 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Handbook of Mutagenicity Test Procedures written by B.J. Kilbey and published by Elsevier. This book was released on 2012-12-02 with total page 876 pages. Available in PDF, EPUB and Kindle. Book excerpt: The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help. This Second Edition updates this information, providing: - a comprehensive bench guide - methods known to be reliable - a broad spectrum of approaches - tips to avoid pitfalls when using unfamiliar techniques - data from population records - safety aspects of mutagens and carcinogens - basic statistical concepts for experiment design This `on the bench' methodological text provides the necessary information for most of the common assays for genetic damage in use. The book includes methods which have been sufficiently used and tested to make their use reliable, but also presents methods which are not widely used at present, but which might prove most useful in screening for mutagenic effects.
