Download or read book Microcalorimetry of Macromolecules written by Peter L. Privalov and published by John Wiley & Sons. This book was released on 2012-07-31 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the physical basis of the structure of macromolecules—proteins, nucleic acids, and their complexes—using calorimetric techniques Many scientists working in biology are unfamiliar with the basics of thermodynamics and its role in determining molecular structures. Yet measuring the heat of structural change a molecule undergoes under various conditions yields information on the energies involved and, thus, on the physical bases of the considered structures. Microcalorimetry of Macromolecules offers protein scientists unique access to this important information. Divided into thirteen chapters, the book introduces readers to the basics of thermodynamics as it applies to calorimetry, the evolution of the calorimetric technique, as well as how calorimetric techniques are used in the thermodynamic studies of macromolecules, detailing instruments for measuring the heat effects of various processes. Also provided is general information on the structure of biological macromolecules, proteins, and nucleic acids, focusing on the key thermodynamic problems relating to their structure. The book covers: The use of supersensitive calorimetric instruments, including micro and nano-calorimeters for measuring the heat of isothermal reactions (Isothermal Titration Nano-Calorimeter), the heat capacities over a broad temperature range (Scanning Nano-Calorimeter), and pressure effects (Pressure Perturbation Nano-Calorimeter) Two of the simplest but key structural elements: the α and polyproline helices and their complexes, the α-helical coiled-coil, and the pyroline coiled-coils Complicated macromolecular formations, including small globular proteins, multidomain proteins and their complexes, and nucleic acids Numerous examples of measuring the ground state of protein energetics, as well as changes seen when proteins interact The book also reveals how intertwined structure and thermodynamics are in terms of a macromolecule's organization, mechanism of formation, the stabilization of its three-dimensional structure, and ultimately, its function. The first book to describe microcalorimetric technique in detail, enough for graduate students and research scientists to successfully plumb the structural mysteries of proteins and the double helix, Microcalorimetry of Macromolecules is an essential introduction to using a microcalorimeter in biological studies.
Download or read book Microcalorimetry of Macromolecules written by Peter L. Privalov and published by John Wiley & Sons. This book was released on 2012-05-29 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the physical basis of the structure of macromolecules—proteins, nucleic acids, and their complexes—using calorimetric techniques Many scientists working in biology are unfamiliar with the basics of thermodynamics and its role in determining molecular structures. Yet measuring the heat of structural change a molecule undergoes under various conditions yields information on the energies involved and, thus, on the physical bases of the considered structures. Microcalorimetry of Macromolecules offers protein scientists unique access to this important information. Divided into thirteen chapters, the book introduces readers to the basics of thermodynamics as it applies to calorimetry, the evolution of the calorimetric technique, as well as how calorimetric techniques are used in the thermodynamic studies of macromolecules, detailing instruments for measuring the heat effects of various processes. Also provided is general information on the structure of biological macromolecules, proteins, and nucleic acids, focusing on the key thermodynamic problems relating to their structure. The book covers: The use of supersensitive calorimetric instruments, including micro and nano-calorimeters for measuring the heat of isothermal reactions (Isothermal Titration Nano-Calorimeter), the heat capacities over a broad temperature range (Scanning Nano-Calorimeter), and pressure effects (Pressure Perturbation Nano-Calorimeter) Two of the simplest but key structural elements: the α and polyproline helices and their complexes, the α-helical coiled-coil, and the pyroline coiled-coils Complicated macromolecular formations, including small globular proteins, multidomain proteins and their complexes, and nucleic acids Numerous examples of measuring the ground state of protein energetics, as well as changes seen when proteins interact The book also reveals how intertwined structure and thermodynamics are in terms of a macromolecule's organization, mechanism of formation, the stabilization of its three-dimensional structure, and ultimately, its function. The first book to describe microcalorimetric technique in detail, enough for graduate students and research scientists to successfully plumb the structural mysteries of proteins and the double helix, Microcalorimetry of Macromolecules is an essential introduction to using a microcalorimeter in biological studies.
Download or read book Microcalorimetry of macromolecules written by and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of macromolecules written by and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of Biological Molecules written by Eric Ennifar and published by Humana. This book was released on 2019-04-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides methods on microcalorimetry approaches to investigate complex biological molecular systems. Chapters guide readers through Differential Scanning Calorimetry (DSC), Isothermal Titration Calorimetry (ITC), and advanced data processing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microcalorimetry of Biological Molecules: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Download or read book Microcalorimetry of Macromolecules written by Blahoslav Sedláček and published by John Wiley & Sons. This book was released on 1981 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of Macromolecules written by International Union of Pure and Applied Chemistry. Macromolecular Division and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Thermal Analysis and Calorimetry written by Richard B. Kemp and published by Elsevier. This book was released on 1999-12-13 with total page 1061 pages. Available in PDF, EPUB and Kindle. Book excerpt: The applications and interest in thermal analysis and calorimetry have grown enormously during the last half of the 20th century. These techniques have become indispensable in the study of processes such as catalysis, hazards evaluation etc., and in measuring important physical properties quickly, conveniently and with markedly improved accuracy. Consequently, thermal analysis and calorimetry have grown in stature and more scientists and engineers have become at least part-time, practitioners. People new to the field therefore need a source of information describing the basic principles and current state of the art. The last volume of this 4 volume handbook, devoted to many aspects of biological thermal analysis and calorimetry, completes a comprehensive review of this important area. All chapters have been prepared by recognized experts in their respective fields. The approach taken is "how and what to do and when to do it". The complete work is a valuable addition to the already existing literature.
Download or read book Microcalorimetry of Macromolecules Proceedings of the 20th Prague IUPAC Microsymposium on Macromolecules 16 19 July 1979 Pramy Macromolecules written by and published by . This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of Macromolecules written by and published by . This book was released on 1980 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of Macromolecules written by and published by . This book was released on 1981 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of Macromolecules written by Československá společnost chemická and published by . This book was released on 1979 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of Macromolecules written by Blahoslav Sedláček and published by . This book was released on 1980 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of Macromolecules Proceedings of the 20 Prague IUPAC Microsymposium on Macromolecules Prague 1979 Held Under the Auspices of the International Union of Pure and Applied Chemistry IUPAC the Czechoslovak Academy of Sciences and the Czechoslovak Chemical Society written by B. Sedlácek and published by . This book was released on 1981 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of Macromolecules written by and published by . This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of macromolecules written by Blahoslav Sedláček and published by . This book was released on 1981 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcalorimetry of Macromolecules written by Blahoslav Sedláček and published by . This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
