Download or read book Principles in Microbiome Engineering written by Matthew W. Chang and published by John Wiley & Sons. This book was released on 2022-05-03 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles in Microbiome Engineering Provides an overview of the techniques and applications insight into the complex composition and interactions of microbiomes Microbiomes, the communities of microorganisms that inhabit specific ecosystems or organisms, can be engineered to modify the structure of microbiota and reestablish ecological balance. In recent years, a better understanding of microbial composition and host-microbe interactions has led to the development of new applications for improving human health and increasing agricultural productivity and quality. Principles in Microbiome Engineering introduces readers to the tools and applications involved in manipulating the composition of a microbial community to improve the function of an eco-system. Covering a range of key topics, this up-to-date volume discusses current research in areas such as microbiome-based therapeutics for human diseases, crop plant breeding, animal husbandry, soil engineering, food and beverage applications, and more. Divided into three sections, the text first describes the critical roles of systems biology, synthetic biology, computer modelling, and machine learning in microbiome engineering. Next, the volume explores various state-of-the-art applications, including cancer immunotherapy and prevention of diseases associated with the human microbiome, followed by a concluding section offering perspectives on the future of microbiome engineering and potential applications. Introduces a variety of applications of microbiome engineering in the fields of medicine, agriculture, and food and beverage products Presents current research into the complex interactions and relationships between microbiomes and biotic and abiotic elements of their environments Examines the use of technologies such as Artificial Intelligence (AI), Machine Learning (ML), and Big Data analytics to advance understanding of microbiomes Discusses the engineering of microbiomes to address human health conditions such as neuro psychiatric disorders and autoimmune and inflammatory diseases Edited and authored by leading researchers in the rapidly evolving field, Principles in Microbiome Engineering is an essential resource for biotechnologists, biochemists, microbiologists, pharmacologists, and practitioners working in the biotechnology and pharmaceutical industries.
Download or read book The Chemistry of Microbiomes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-19 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.
Download or read book Environmental Chemicals the Human Microbiome and Health Risk written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-03-01 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemicalâ€"microbiome interactions.
Download or read book Microbiome Engineering written by Nimmy Srivastava and published by . This book was released on 2024-11-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book compiles the latest techniques and applications of microbiome engineering. It covers the omics tools in microbial research, strategies to engineer human microbiomes, and the application of synthetic biology to build smart microbes. It includes the application of microbiome engineering on improving human health.
Download or read book The Plant Microbiome in Sustainable Agriculture written by Alok Kumar Srivastava and published by John Wiley & Sons. This book was released on 2021-02-16 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most up-to-date reference on phytomicrobiomes available today The Plant Microbiome in Sustainable Agriculture combines the most relevant and timely information available today in the fields of nutrient and food security. With a particular emphasis on current research progress and perspectives of future development in the area, The Plant Microbiome in Sustainable Agriculture is an invaluable reference for students and researchers in the field, as well as those with an interest in microbiome research and development. The book covers both terrestrial and crop associated microbiomes, unveiling the biological, biotechnological and technical aspects of research. Topics discussed include: Developing model plant microbiome systems for various agriculturally important crops Defining core microbiomes and metagenomes in these model systems Defining synthetic microbiomes for a sustainable increase in food production and quality The Plant Microbiome in Sustainable Agriculture is written to allow a relative neophyte to learn and understand the basic concepts involved in phytomicrobiomes and discuss them intelligently with colleagues.
Download or read book Microbiomes of the Built Environment written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-06 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: People's desire to understand the environments in which they live is a natural one. People spend most of their time in spaces and structures designed, built, and managed by humans, and it is estimated that people in developed countries now spend 90 percent of their lives indoors. As people move from homes to workplaces, traveling in cars and on transit systems, microorganisms are continually with and around them. The human-associated microbes that are shed, along with the human behaviors that affect their transport and removal, make significant contributions to the diversity of the indoor microbiome. The characteristics of "healthy" indoor environments cannot yet be defined, nor do microbial, clinical, and building researchers yet understand how to modify features of indoor environmentsâ€"such as building ventilation systems and the chemistry of building materialsâ€"in ways that would have predictable impacts on microbial communities to promote health and prevent disease. The factors that affect the environments within buildings, the ways in which building characteristics influence the composition and function of indoor microbial communities, and the ways in which these microbial communities relate to human health and well-being are extraordinarily complex and can be explored only as a dynamic, interconnected ecosystem by engaging the fields of microbial biology and ecology, chemistry, building science, and human physiology. This report reviews what is known about the intersection of these disciplines, and how new tools may facilitate advances in understanding the ecosystem of built environments, indoor microbiomes, and effects on human health and well-being. It offers a research agenda to generate the information needed so that stakeholders with an interest in understanding the impacts of built environments will be able to make more informed decisions.
Download or read book Beneficial Plant Bacterial Interactions written by Bernard R. Glick and published by Springer Nature. This book was released on 2020-06-08 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a straightforward and easy-to-understand overview of beneficial plant-bacterial interactions. It features a wealth of unique illustrations to clarify the text, and each chapter includes study questions that highlight the important points, as well as references to key experiments. Since the publication of the first edition of Beneficial Plant-Bacterial Interactions, in 2015, there has been an abundance of new discoveries in this area, and in recent years, scientists around the globe have begun to develop a relatively detailed understanding of many of the mechanisms used by bacteria that facilitate plant growth and development. This knowledge is gradually becoming an integral component of modern agricultural practice, with more and more plant growth-promoting bacterial strains being commercialized and used successfully in countries throughout the world. In addition, as the world’s population continues to grow, the pressure for increased food production will intensify, while at the same time, environmental concerns, mean that environmentally friendly methods of food production will need to replace many traditional agricultural practices such as the use of potentially dangerous chemicals. The book, intended for students, explores the fundamentals of this new paradigm in agriculture, horticulture, and environmental cleanup.
Download or read book Human and Animal Microbiome Engineering written by Dharumadurai Dhanasekaran and published by Academic Press. This book was released on 2025-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human and Animal Microbiome Engineering provides both basic and detailed information about microbiome engineering for the health enhancement of humans and animal populations. Contents provide updated information about current research topics in this emerging field including microbiome gene therapy, engineered probiotics and smart living biotic machines for the release of therapeutics. The book is divided into 4 sections covering microbiome engineering application with a focus on future perspectives in human health and enhancement; microbiome engineering in human health and disease including real-world case studies; animal microbiome engineering essentials; and microbiome engineering for livestock improvement. This is the perfect reference for researchers and scientists to further explore the relationship between host and microbiome and discover novel ideas about the concepts of microbiome engineering in the health enhancement of humans and animal populations.
Download or read book Animal Models for Microbiome Research written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-05-23 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: The surface of the human body and its mucous membranes are heavily colonized by microorganisms. Our understanding of the contributions that complex microbial communities make to health and disease is advancing rapidly. Most microbiome research to date has focused on the mouse as a model organism for delineating the mechanisms that shape the assembly and dynamic operations of microbial communities. However, the mouse is not a perfect surrogate for studying different aspects of the microbiome and how it responds to various environmental and host stimuli, and as a result, researchers have been conducting microbiome studies in other animals. To examine the different animal models researchers employ in microbiome studies and to better understand the strengths and weaknesses of each of these model organisms as they relate to human and nonhuman health and disease, the Roundtable on Science and Welfare in Laboratory Animal Use of the National Academies of Sciences, Engineering, and Medicine convened a workshop in December 2016. The workshop participants explored how to improve the depth and breadth of analysis of microbial communities using various model organisms, the challenges of standardization and biological variability that are inherent in gnotobiotic animal-based research, the predictability and translatability of preclinical studies to humans, and strategies for expanding the infrastructure and tools for conducting studies in these types of models. This publication summarizes the presentations and discussions from the workshop.
Download or read book Microbial Engineering for Therapeutics written by Mrutyunjay Suar and published by Springer Nature. This book was released on 2022-10-29 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the recent advances in the field of microbial engineering and its application in human healthcare. It underscores the systemic and synthetic biology approaches for engineering microbes and discusses novel treatments for inflammatory bowel diseases based on engineered probiotics. The book also reviews the different options and methods for engineering microbes, ranging from recombinant DNA technology to designing microbes for targeting specific sites and delivering therapeutics. Further, it discusses genetically engineered microorganisms for smart diagnostics and describes current approaches in microbial gene editing using CRISPR-Cas9-based tools. Lastly, it summarizes the potential applications of human microbiome engineering in improving human health and explores potential strategies for scaling-up the production of engineered microbial strains for commercial purposes, as well as the challenges. Given its scope, this book is a valuable resource for students, researchers, academics and entrepreneurs interested in understanding microbial engineering for the production of commercial products.
Download or read book The Human Microbiome Diet and Health written by Food Forum and published by National Academies Press. This book was released on 2013-02-27 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.
Download or read book Core Microbiome written by Javid A. Parray and published by John Wiley & Sons. This book was released on 2022-05-10 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improve the quality and productivity of your crops through selecting positive and effective interactive core-microbiomes As microbial cells are present in overwhelming numbers in our soil, it is perhaps inevitable that microbes are found extensively in plant and animal tissue. The role of microbiomes on the regulation of physiological processes in animals has been extensively researched in recent years, but the overarching role of the plant microbiome has yet to be discovered. Core Microbiome: Improving Crop Quality and Productivity is an attempt to remediate some of that deficit, as the first book to summarize feature of microbial communities that make up the plant microbiome. There is substantial evidence that these communities are crucial in disease control, enhanced nutrient acquisition, and stress tolerance—a feature more important than ever due to climate change. A further focus on improving how core microbiomes interact so that they are both phenotypically and genotypically very adaptive and sustainable will allow the reader to improve the quality and productivity of crops so that they may be considered sustainable agriculture. Core Microbiome readers will also find: Descriptions of the basic structure of core microbiomes and their functions across various habitats New and cutting-edge trends and technological innovations highlighted that use core microbiomes to harness plant microbiome interaction The structure, classification, and biotechnological applications of aquatic core microbiomes, in addition to the material on plant microbiomes As a broad introduction to the interaction of core microbiome and plant productivity, Core Microbiome is ideal for researchers and scientists working in the field of environmental science, environmental microbiology, and waste management. Similarly, undergraduate and graduate students in these fields, as well as in agriculture, biotechnology, biosciences, and life and environmental sciences will also benefit from this work.
Download or read book Plant Microbiome for Plant Productivity and Sustainable Agriculture written by Sagar Chhabra and published by Springer Nature. This book was released on 2023-01-05 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book deals with latest comprehensive information on conventional and high throughput techniques and technologies that are recently used to study plant microbial interface for agricultural research and enhancing plant productivity. Plant microbiota are important for many plant growth promotion activity and agricultural productivity and are sustainable green technology for enhancing agricultural productivity under changing environment. The book covers recent information about the plant associated microbiota and their ecology. It discusses technologies to isolate and test microbiota inhabiting in different portion of plants. The book explores the conventional methods as well as the most recently recognized high throughput technologies which are important for productive agroecosystems to feed the growing global population. This book is of interest to teachers, researchers, microbiologist, plant and environmental scientist and those interested in environment stewardship around the world. Also the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences and policy makers to be a useful to read.
Download or read book Climate Change and the Microbiome written by D. K. Choudhary and published by Springer Nature. This book was released on 2021-10-13 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the impact of climate change on the soil microbiome and its subsequent effects on plant health, soil-plant dynamics, and the ecosphere. It also discusses emerging ideas to counteract these effects, e.g., through agricultural applications of functional microbes, to ensure a sustainable ecosystem. Climate change is altering the soil microbiome distributions and thus the interactions in microbiome and plant‐soil microorganism. Improvement of our understanding of microbe-microbe and plant-microbe interaction under changing climatic conditions is essential, because the overall impact of these interactions under varying adverse environmental conditions is lacking. This book has been designed to understand the impact of climate change, i.e., mainly salt and drought stress, on the soil microbiome and its impact on plant, yield, and the ecosphere. The book is organized into four parts: The first part reviews the impact of climate change on the diversity and richness of the soil microbiome. The second part addresses effects of climate change on plant health. The third part discusses effects on soil-plant dynamics and functionality, e.g., soil productivity. The final part deals with the effects of climate change on ecosystem functioning and also discusses potential solutions. The book will appeal to students and researchers working in the area of soil science, agriculture, molecular biology, plant physiology, and biotechnology.
Download or read book Microbiome Therapeutics written by Nar Singh Chauhan and published by Elsevier. This book was released on 2023-05-17 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiome Therapeutics: Personalized Therapy Beyond Conventional Approaches addresses the current knowledge and landscape of microbiome therapeutics, providing an overview of existing applications in health and disease as well as potential future directions of microbiome modulations and subsequent translation to the global industry and market. This important reference provides the most current status of microbiome therapeutics as well as possible future perspectives through coverage of topics including the application of microbiome therapeutics; various additive, subtractive and modulatory approaches; microbiome composition of health and diseases, insights into live bio-therapeutics and the clinical data supporting their efficacy. Case studies are provided throughout the book to further define, describe and evaluate microbiome therapeutics success and failure. Provides chapters focused on illness types to address the potential of microbiome therapeutics in several significant disorders Offers human gut microbiome explorations that have enriched the understanding of microbiome colonization, maturation, and dysbiosis in health and disease subsets Addresses important concepts like economic potential in the global therapeutics market as well as ethical, technical, and regulatory aspects
Download or read book Climate Change and Microbiome Dynamics written by Javid Ahmad Parray and published by Springer Nature. This book was released on 2023-01-01 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an overview relevant to various biological mechanisms that regulate carbon exchanges between the major components and their response to climate change. Climate change has a significant impact on people's lives, energy demand, food security, etc. The soil microbial ecology is vital for assessing terrestrial and aquatic carbon cycles and climate feedback. However, the primary concern is the complexity of the soil microbial community and its severely affected functions due to the climate and other global changes. Global warming comprises an assessment of the dynamic interactions and feedback between microbes, plants, and their physical environment due to climate change. The book will address the need to use a multifactor experimental approach to understand how soil microorganisms and their activities adapt to climate change and the implications of carbon cycle feedback. The most pressing concern is a clearer understanding of the biological factors that regulate carbon exchanges between land, oceans, and the atmosphere and how these exchanges will respond to climate change via climate–ecosystem feedbacks, which could augment or quell regional and global climate change. Terrestrial ecosystems play an important role in climate feedback as they produce and absorb greenhouse gases like carbon dioxide, methane, and nitrous oxides. They also strongly contribute to storing enormous amounts of carbon in living vegetation and soils, rendering them a significant global carbon sink. If climate change projections are realistic, such a rapid increase in carbon loss from soil could exacerbate the soil carbon cycle feedback. The book will determine the role of microbial feedback in regulating soil-land-atmosphere carbon exchange under changing climatic conditions at the regional and global levels. The current book will also focus on recent research designed to use beneficial microbes such as plant growth-promoting microorganisms, fungi, endophytic microbes, and others to improve understanding of the interaction and their potential role in promoting advanced management for sustainable agricultural solutions. Understanding the influence on the native microbiome, such as the distribution of methanogens and methanotrophs, nutritional content, microbial biomass, and other factors, is becoming increasingly crucial to establishing climate-resilient agriculture.
Download or read book Human Microbiome in Health Disease and Therapy written by Pallaval Veera Bramhachari and published by Springer Nature. This book was released on 2024-01-15 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the role of the human microbiome in health and diseases. It discusses the association of an imbalanced human microbiome with different human diseases, including inflammatory, metabolic conditions, neurological, cardiovascular, and respiratory diseases. The book further reviews the association between intestinal microbiota and immune defense systems. The book provides evolving knowledge of the development, complexity, and functionality of the healthy gut microbiota and covers interventions that modulate and stabilize the gut microbiota. Further, it introduces the human microbiome as a reservoir of AMR genes, the current knowledge on the resistome, and the recent and upcoming advances in molecular diagnostic approaches to unravel this reservoir. Toward the end, the book reviews the advances in understanding the human urinary microbiome and its potential role in urinary tract infection. The chapter also presents the dynamics of the skin microbiome and the association of microbiota with skin disorders and therapeutic interventions. This book is an invaluable read for health professionals, medical students, microbiologists, and scientific research communities who are eager to update themselves with recent trends in microbiome research.
