Download or read book Microarrays and Combinatorial Technologies for Biomedical Applications II written by Dan V. Nicolau and published by . This book was released on 2004 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microarrays and Combinatorial Technologies for Biomedical Applications written by Dan V. Nicolau and published by SPIE-International Society for Optical Engineering. This book was released on 2003 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microarrays and Combinatorial Technologies for Biomedical Applications written by and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microarrays and Combinatorial Techniques Design Fabrication and Analysis II written by Dan V. Nicolau and published by SPIE-International Society for Optical Engineering. This book was released on 2004 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of SPIE present the original research papers presented at SPIE conferences and other high-quality conferences in the broad-ranging fields of optics and photonics. These books provide prompt access to the latest innovations in research and technology in their respective fields. Proceedings of SPIE are among the most cited references in patent literature.
Download or read book Microarray Technology and Its Applications written by Uwe R. Müller and published by Springer Science & Business Media. This book was released on 2006-03-30 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ithasbeenstatedthatourknowledgedoublesevery20years,butthatmaybe an understatement when considering the Life Sciences. A series of discoveries and inventions have propelled our knowledge from the recognition that DNA isthegeneticmaterialtoabasicmolecularunderstandingofourselvesandthe living world around us in less than 50 years. Crucial to this rapid progress was thediscoveryofthedouble-helicalstructureofDNA,whichlaidthefoundation forallhybridizationbasedtechnologies. Thediscoveriesofrestrictionenzymes, ligases, polymerases, combined with key innovations in DNA synthesis and sequencing ushered in the era of biotechnologyas a new science with profound sociological and economic implications that are likely to have a dominating in?uence on the development of our society during this century. Given the process by which science builds on prior knowledge, it is perhaps unfair to single out a few inventions and credit them with having contributed most to thisavalancheofknowledge. Yet,therearesurelysomethatwillberecognized as having had a more profound impact than others, not just in the furthering of our scienti?c knowledge, but by leveraging commercial applications that provide a tangible return to our society. The now famous Polymerase Chain Reaction, or PCR, is surely one of those, as it has uniquely catalyzed molecular biology during the past 20 years, and continues to have a signi?cant impact on all areas that involve nucleic acids, ranging from molecular pathology to forensics. Ten years ago micro- ray technology emerged as a new and powerful tool to study nucleic acid - quences in a highly multiplexed manner, and has since found equally exciting and useful applications in the study of proteins, metabolites, toxins, viruses, whole cells and even tissues.
Download or read book Combinatorial Chemistry and Technologies written by Stanislav Miertus and published by CRC Press. This book was released on 2005-04-12 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several books on the market cover combinatorial techniques, but they offer just a limited perspective of the field, focusing on selected aspects without examining all approaches and integrated technologies. Combinatorial Chemistry and Technologies: Methods and Applications answers the demand for a complete overview of the field, covering all of the methodologies used in the design, synthesis, and screening of molecular libraries. Now in its second edition, this volume updates prior content and explores new areas such as catalysis, applications in biotechnology, and current ICS-UNIDO activities. Topics include the generation of molecular diversity by chemical methods using solution- and solid-phase chemistries, biological approaches for the production and screening of peptides, antibody and oligonucleotide libraries, and the application of computer-assisted approaches to guide library synthesis. The book establishes the link between combinatorial chemistry and molecular modeling and illustrates the importance of economics and patenting in combinatorial technologies. Valuable to technologists and researchers as an introductory survey on the many aspects of combinatorial chemistry and combinatorial technology, Combinatorial Chemistry and Technologies: Methods and Applications offers an overview of a field that promises broad applicability in the identification of new drugs, as well as in diagnostics, new materials, and catalysis.
Download or read book BioMEMS and Biomedical Nanotechnology written by Mihrimah Ozkan and published by Springer. This book was released on 2016-08-23 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microarray Innovations written by Gary Hardiman and published by CRC Press. This book was released on 2009-04-02 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarr
Download or read book Microarrays written by Kilian Dill and published by Springer Science & Business Media. This book was released on 2008-12-30 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combinatorial chemistry is used to find materials that form sensor microarrays. This book discusses the fundamentals, and then proceeds to the many applications of microarrays, from measuring gene expression (DNA microarrays) to protein-protein interactions, peptide chemistry, carbodhydrate chemistry, electrochemical detection, and microfluidics.
Download or read book Microarray Technology Through Applications written by and published by Taylor & Francis. This book was released on with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methods in Microarray Normalization written by Phillip Stafford and published by CRC Press. This book was released on 2008-01-31 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This organized text compiles, for the first time, the most useful normalization methods developed for interpreting microarray data. Experts examine the mathematical processes that are important in normalizing data and avoiding inherent systematic biases. They also review modern software, including discussions on key algorithms, comparative data, and download locations. The book contains the latest microarray innovations from companies such as Agilent, Affymetrix, and GeneGo as well as new, readily adaptable normalization methods for expression and CGH arrays. It also lists of open-source molecular profiling normalization algorithms available and where to access them.
Download or read book BioMEMS and Biomedical Nanotechnology written by Mihrimah Ozkan and published by Springer Science & Business Media. This book was released on 2007-04-03 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributions reporting on fundamental and applied investigations of the material science, biochemistry, and physics of biomedical microdevices with applications to Genomics and Proteomics. Topics include gene expression profiling utilizing microarray technology; imaging and sensing for gene detection and use in DNA analysis; and coverage of advanced microfluidic devices and the Humane Genome Project.
Download or read book Applying Genomic and Proteomic Microarray Technology in Drug Discovery Second Edition written by Robert S. Matson and published by CRC Press. This book was released on 2013-03-13 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microarrays play an increasingly significant role in drug discovery. The commercial landscape has changed dramatically over the past few years and researchers have made great advancements with regard to construction and use. Now in its second edition, Applying Genomic and Proteomic Microarray Technology in Drug Discovery highlights, describes, and evaluates current scientific research using microarray technology in genomic and proteomic applications. Updated and revised to reflect recent progress in the field, the second edition discusses: Expanded omics-driven applications, including the areas of metabolomics and chemical biology The commercialization of the microarray platform, with a historical perspective aimed at recognizing key technological developments Solid-supports (substrates) and surface chemistries currently used in the creation of nucleic acid and protein microarrays Different approaches to producing microarrays that achieve spot equality with the same number of molecules properly oriented The development of the gene expression microarray and representative applications The development of protein microarray technology, including its history and key applications Unique to this edition is a new chapter on multiplex assays that examines the development and applications of arrays across diverse platforms. It discusses applications for qPCR, multiplex lateral flow, and multiplex bead assays. It also presents platform-to-platform comparisons. Microarrays remain an invaluable tool for omics-based research not only in drug discovery, but in the life sciences, in clinical research, and for diagnostic applications worldwide. This volume presents the current state of the art on the utility of this technology to solve a host of important biological problems.
Download or read book Microarrays and Microplates written by Ian Day and published by Taylor & Francis. This book was released on 2023-05-31 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 'Advanced Methods' series is intended for advanced undergraduates, postgraduates and established research scientists. Titles in the series are designed to cover current important areas of research in life sciences, and include both theoretical background and detailed protocols. The aim is to give researchers sufficient theory, supported by references, to take the given protocols and adapt them to their particular experimental systems. Microarrays and Microplates title looks at the new microarray and microplate-based technologies which facilitate large-scale analysis of DNA sequence variants, mRNA molecules and proteins. The book provides a review of the various methodologies being used to identify genetic variants and gene regulation and guides readers through both the application of these methodologies and experimental procedures.
Download or read book Advanced Photonic Structures for Biological and Chemical Detection written by Xudong Fan and published by Springer Science & Business Media. This book was released on 2009-08-29 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: In my career I’ve found that ‘‘thinking outside the box’’ works better if I know what’s ‘‘inside the box.’’ Dave Grusin, composer and jazz musician Different people think in different time frames: scientists think in decades, engineers think in years, and investors think in quarters. Stan Williams, Director of Quantum Science Research, Hewlett Packard Laboratories Everything can be made smaller, never mind physics; Everything can be made more ef?cient, never mind thermodynamics; Everything will be more expensive, never mind common sense. Tomas Hirschfeld, pioneer of industrial spectroscopy Integrated Analytical Systems Series Editor: Dr. Radislav A. Potyrailo, GE Global Research, Niskayuna, NY The book series Integrated Analytical Systems offers the most recent advances in all key aspects of development and applications of modern instrumentation for che- cal and biological analysis. The key development aspects include (i) innovations in sample introduction through micro- and nano?uidic designs, (ii) new types and methods of fabrication of physical transducers and ion detectors, (iii) materials for sensors that became available due to the breakthroughs in biology, combinatorial materials science, and nanotechnology, and (iv) innovative data processing and mining methodologies that provide dramatically reduced rates of false alarms.
Download or read book DNA Microarrays for Biomedical Research written by Martin Dufva and published by Humana Press. This book was released on 2011-01-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA microarray technology has revolutionized research in the past decade. Initially an application for mRNA expression studies, the technology now has spread to other applications such as comparative genomic hybridization, SNP and mutation analysis. In DNA Microarrays for Biomedical Research: Methods and Protocols, experts explore these now commonly used applications, addressing probe design strategies, fabrication issues and providing practical examples of detailed methods for generation of high quality DNA microarray data. Chapters incorporate information on some of the largest providers of microarray, including Affymetrix, Ilumina and Agilent, and their use on a variety of applications. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Authoritative and highly practical, DNA Microarrays for Biomedical Research: Methods and Protocols presents a variety of protocols which can be easily reproduced, allowing researchers to gain surprising insight into the complex world of DNA microarray technology.
Download or read book Microarrays written by James V. Rogers and published by Nova Biomedical Books. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sequencing of the human genome was a pivotal event in science that opened the door to exploring the structure and function of genes and their regulation. The activation or suppression of transcribed genes is critical to the orchestration of everyday biological processes at the cellular, tissue, and physiological levels. The rapid advance of science and technology has yielded the development of the microarray technique, which has propelled a much deeper understanding of the genome. By combining these technological advances in microarrays with statistical and bioinformatics software, investigators are now able to perform scientific investigations geared towards answering unique biological problems that encompass many fields of research from genetics and evolution to molecular medicine, health, and disease. This book provides an overview of the use and application of microarrays throughout the life sciences to address diverse complex biological questions. In this collection, authors present information on using microarrays to unlock molecular mechanisms and gene expression patterns associated with research areas ranging from biodefense, pathological changes, and monitoring antimicrobial resistance genes to diagnostics, marine biodiversity, and dermal toxicology.
