Download or read book Micro Electrode Dot Array Digital Microfluidic Biochips written by Zipeng Li and published by Springer. This book was released on 2018-12-14 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.

Download or read book Error Tolerant Biochemical Sample Preparation with Microfluidic Lab on Chip written by Sudip Poddar and published by CRC Press. This book was released on 2022-07-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic biochips have gained prominence due to their versatile applications to biochemistry and health-care domains such as point-of-care clinical diagnosis of tropical and cardiovascular diseases, cancer, diabetes, toxicity analysis, and for the mitigation of the global HIV crisis, among others. Microfluidic Lab-on-Chips (LoCs) offer a convenient platform for emulating various fluidic operations in an automated fashion. However, because of the inherent uncertainty of fluidic operations, the outcome of biochemical experiments performed on-chip can be erroneous even if the chip is tested a priori and deemed to be defect-free. This book focuses on the issues encountered in reliable sample preparation with digital microfluidic biochips (DMFBs), particularly in an error-prone environment. It presents state-of-the-art error management techniques and underlying algorithmic challenges along with their comparative discussions. Describes a comprehensive framework for designing a robust and error-tolerant biomedical system which will help in migrating from cumbersome medical laboratory tasks to small-sized LOC-based systems Presents a comparative study on current error-tolerant strategies for robust sample preparation using DMFBs and reports on efficient algorithms for error-tolerant sample dilution using these devices Illustrates how algorithmic engineering, cyber-physical tools, and software techniques are helpful in implementing fault tolerance Covers the challenges associated with design automation for biochemical sample preparation Teaches how to implement biochemical protocols using software-controlled microfluidic biochips Interdisciplinary in its coverage, this reference is written for practitioners and researchers in biochemical, biomedical, electrical, computer, and mechanical engineering, especially those involved in LOC or bio-MEMS design.

Download or read book Security of Biochip Cyberphysical Systems written by Shayan Mohammed and published by Springer Nature. This book was released on 2022-03-28 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with a valuable guide to understanding security and the interplay of computer science, microfluidics, and biochemistry in a biochip cyberphysical system (CPS). The authors uncover new, potential threat and trust-issues to address, as this emerging technology is poised to be adapted at a large scale. Readers will learn how to secure biochip CPS by leveraging the available resources in different application contexts, as well as how to ensure intellectual property (IP) is protected against theft and counterfeits. This book enables secure biochip CPS design by helping bridge the knowledge gap at the intersection of the multi-disciplinary technology that drives biochip CPS.

Download or read book Exact Design of Digital Microfluidic Biochips written by Oliver Keszocze and published by Springer. This book was released on 2018-06-11 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents exact, that is minimal, solutions to individual steps in the design process for Digital Microfluidic Biochips (DMFBs), as well as a one-pass approach that combines all these steps in a single process. All of the approaches discussed are based on a formal model that can easily be extended to cope with further design problems. In addition to the exact methods, heuristic approaches are provided and the complexity classes of various design problems are determined. Presents exact methods to tackle a variety of design problems for Digital Microfluidic Biochips (DMFBs); Describes an holistic, one-pass approach solving different design steps all at once; Based on a formal model of DMFBs that is easily adaptable to deal with further design tasks.

Download or read book Computer Aided Design of Microfluidic Very Large Scale Integration mVLSI Biochips written by Kai Hu and published by Springer. This book was released on 2017-04-05 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of flow-based, microfluidic VLSI. The authors describe and solve in a comprehensive and holistic manner practical challenges such as control synthesis, wash optimization, design for testability, and diagnosis of modern flow-based microfluidic biochips. They introduce practical solutions, based on rigorous optimization and formal models. The technical contributions presented in this book will not only shorten the product development cycle, but also accelerate the adoption and further development of modern flow-based microfluidic biochips, by facilitating the full exploitation of design complexities that are possible with current fabrication techniques.

Download or read book Languages Design Methods and Tools for Electronic System Design written by Tom J. Kazmierski and published by Springer Nature. This book was released on 2019-12-20 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together a selection of the best papers from the twenty-first edition of the Forum on specification and Design Languages Conference (FDL), which took place on September 10-12, 2018, in Munich, Germany. FDL is a well-established international forum devoted to dissemination of research results, practical experiences and new ideas in the application of specification, design and verification languages to the design, modeling and verification of integrated circuits, complex hardware/software embedded systems, and mixed-technology systems. Covers Assertion Based Design, Verification & Debug; Includes language-based modeling and design techniques for embedded systems; Covers design, modeling and verification of mixed physical domain and mixed signal systems that include significant analog parts in electrical and non-electrical domains; Includes formal and semi-formal system level design methods for complex embedded systems based on the Unified Modelling Language (UML) and Model Driven Engineering (MDE).

Download or read book Digital Microfluidic Biochips written by Krishnendu Chakrabarty and published by CRC Press. This book was released on 2018-10-03 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.

Download or read book Emerging Topics in Hardware Security written by Mark Tehranipoor and published by Springer Nature. This book was released on 2021-04-30 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of emerging topics in the field of hardware security, such as artificial intelligence and quantum computing, and highlights how these technologies can be leveraged to secure hardware and assure electronics supply chains. The authors are experts in emerging technologies, traditional hardware design, and hardware security and trust. Readers will gain a comprehensive understanding of hardware security problems and how to overcome them through an efficient combination of conventional approaches and emerging technologies, enabling them to design secure, reliable, and trustworthy hardware.

Download or read book Secure and Trustworthy Cyberphysical Microfluidic Biochips written by Jack Tang and published by Springer. This book was released on 2019-05-28 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes novel hardware security and microfluidic biochip design methodologies to protect against tampering attacks in cyberphysical microfluidic biochips (CPMBs). It also provides a general overview of this nascent area of research, which will prove to be a vital resource for practitioners in the field.This book shows how hardware-based countermeasures and design innovations can be a simple and effective last line of defense, demonstrating that it is no longer justifiable to ignore security and trust in the design phase of biochips.

Download or read book Designing Droplet Microfluidic Networks written by Andreas Grimmer and published by Springer. This book was released on 2019-07-04 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes automatic methods for the design of droplet microfluidic networks. The authors discuss simulation and design methods which support the design process of droplet microfluidics in general, as well as design methods for a dedicated droplet routing mechanism, namely passive droplet routing. The methods discussed allow for simulating a microfluidic design on a high-abstraction level, which facilitates early validation of whether a design works as intended, automatically dimensioning a microfluidic design, so that constraints like flow conditions are satisfied, and automatically generating meander designs for the respective needs and fabrication settings. Dedicated methods for passive droplet routing are discussed and allow for designing application-specific architectures for a given set of experiments, as well as generating droplet sequences realizing the respective experiments. Together, these methods provide a comprehensive “toolbox" for designers working on droplet microfluidic networks in general and an integrated design flow for the passive droplet routing mechanism in particular. Provides both a comprehensive “toolbox" for designers working on droplet microfluidic networks in general and an integrated design flow for the passive droplet routing mechanism in particular; Describes for the first time CAD methods for droplet microfluidic networks, along with the first integrated design process; Includes open source implementations, in order to reach the largest possible user group within the domain of microfluidics.

Download or read book Security Opportunities in Nano Devices and Emerging Technologies written by Mark Tehranipoor and published by CRC Press. This book was released on 2017-11-22 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The research community lacks both the capability to explain the effectiveness of existing techniques and the metrics to predict the security properties and vulnerabilities of the next generation of nano-devices and systems. This book provides in-depth viewpoints on security issues and explains how nano devices and their unique properties can address the opportunities and challenges of the security community, manufacturers, system integrators, and end users. This book elevates security as a fundamental design parameter, transforming the way new nano-devices are developed. Part 1 focuses on nano devices and building security primitives. Part 2 focuses on emerging technologies and integrations.

Download or read book Emerging Electronic Devices Circuits and Systems written by Chandan Giri and published by Springer Nature. This book was released on 2023-06-01 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book constitutes peer-reviewed proceedings of a workshop on Emerging Electronics Devices, Circuits, and Systems (EEDCS) held in conjunction with International Symposium on Devices, Circuits, and Systems (ISDCS 2022). The book focuses on the recent development in devices, circuits, and systems. It also discusses innovations, trends, practical challenges, and solutions adopted in device design, modeling, fabrication, characterization, and their circuit implementation with pertinent system applications. It will be useful for researchers, developers, engineers, academicians, and students.

Download or read book Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber Physical Microfluidic Platforms written by Mohamed Ibrahim and published by CRC Press. This book was released on 2020-05-31 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: A microfluidic biochip is an engineered fluidic device that controls the flow of analytes, thereby enabling a variety of useful applications. According to recent studies, the fields that are best set to benefit from the microfluidics technology, also known as lab-on-chip technology, include forensic identification, clinical chemistry, point-of-care (PoC) diagnostics, and drug discovery. The growth in such fields has significantly amplified the impact of microfluidics technology, whose market value is forecast to grow from $4 billion in 2017 to $13.2 billion by 2023. The rapid evolution of lab-on-chip technologies opens up opportunities for new biological or chemical science areas that can be directly facilitated by sensor-based microfluidics control. For example, the digital microfluidics-based ePlex system from GenMarkDx enables automated disease diagnosis and can bring syndromic testing near patients everywhere. However, as the applications of molecular biology grow, the adoption of microfluidics in many applications has not grown at the same pace, despite the concerted effort of microfluidic systems engineers. Recent studies suggest that state-of-the-art design techniques for microfluidics have two major drawbacks that need to be addressed appropriately: (1) current lab-on-chip systems were only optimized as auxiliary components and are only suitable for sample-limited analyses; therefore, their capabilities may not cope with the requirements of contemporary molecular biology applications; (2) the integrity of these automated lab-on-chip systems and their biochemical operations are still an open question since no protection schemes were developed against adversarial contamination or result-manipulation attacks. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms provides solutions to these challenges by introducing a new design flow based on the realistic modeling of contemporary molecular biology protocols. It also presents a microfluidic security flow that provides a high-level of confidence in the integrity of such protocols. In summary, this book creates a new research field as it bridges the technical skills gap between microfluidic systems and molecular biology protocols but it is viewed from the perspective of an electronic/systems engineer.

Download or read book Proceedings of 4th International Conference on Frontiers in Computing and Systems written by Dipak Kumar Kole and published by Springer Nature. This book was released on with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Research on Power and Energy System Optimization written by Kumar, Pawan and published by IGI Global. This book was released on 2018-03-16 with total page 777 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the development of advanced structures for providing sustainable energy has been a topic at the forefront of public and political conversation. Many are looking for advancements on pre-existing sources and new and viable energy options to maintain a modern lifestyle. The Handbook of Research on Power and Energy System Optimization is a critical scholarly resource that examines the usage of energy in relation to the perceived standard of living within a country and explores the importance of energy structure augmentation. Featuring coverage on a wide range of topics including energy management, micro-grid, and distribution generation, this publication is targeted towards researchers, academicians, and students seeking relevant research on the augmentation of current energy structures to support existing standards of living.

Download or read book Automated Technology for Verification and Analysis written by Dang Van Hung and published by Springer Nature. This book was released on 2020-10-12 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 18th International Symposium on Automated Technology for Verification and Analysis, ATVA 2020, held in Hanoi, Vietnam, in October 2020. The 27 regular papers presented together with 5 tool papers and 2 invited papers were carefully reviewed and selected from 75 submissions. The symposium is dedicated to promoting research in theoretical and practical aspects of automated analysis, verification and synthesis by providing an international venue for the researchers to present new results. The papers focus on neural networks and machine learning; automata; logics; techniques for verification, analysis and testing; model checking and decision procedures; synthesis; and randomization and probabilistic systems.

Download or read book Algorithms for Sample Preparation with Microfluidic Lab on Chip written by Sukanta Bhattacharjee and published by CRC Press. This book was released on 2022-09-01 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip