Download or read book Methods of Small Parameter in Mathematical Biology written by Jacek Banasiak and published by Springer Science & Business. This book was released on 2014-04-19 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph presents new tools for modeling multiscale biological processes. Natural processes are usually driven by mechanisms widely differing from each other in the time or space scale at which they operate and thus should be described by appropriate multiscale models. However, looking at all such scales simultaneously is often infeasible, costly, and provides information that is redundant for a particular application. Hence, there has been a growing interest in providing a more focused description of multiscale processes by aggregating variables in a way that is relevant to the purpose at hand and preserves the salient features of the dynamics. Many ad hoc methods have been devised, and the aim of this book is to present a systematic way of deriving the so-called limit equations for such aggregated variables and ensuring that the coefficients of these equations encapsulate the relevant information from the discarded levels of description. Since any approximation is only valid if an estimate of the incurred error is available, the tools the authors describe allow for proving that the solutions to the original multiscale family of equations converge to the solution of the limit equation if the relevant parameter converges to its critical value. The chapters are arranged according to the mathematical complexity of the analysis, from systems of ordinary linear differential equations, through nonlinear ordinary differential equations, to linear and nonlinear partial differential equations. Many chapters begin with a survey of mathematical techniques needed for the analysis. All problems discussed in this book belong to the class of singularly perturbed problems; that is, problems in which the structure of the limit equation is significantly different from that of the multiscale model. Such problems appear in all areas of science and can be attacked using many techniques. Methods of Small Parameter in Mathematical Biology will appeal to senior undergraduate and graduate students in applied and biomathematics, as well as researchers specializing in differential equations and asymptotic analysis.
Download or read book Mathematical Modeling in Biology written by Shandelle M. Henson and published by CRC Press. This book was released on 2022-12-29 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Modeling in Biology: A Research Methods Approach is a textbook written primarily for advanced mathematics and science undergraduate students and graduate-level biology students. Although the applications center on ecology, the expertise of the authors, the methodology can be imported to any other science, including social science and economics. The aim of the book, beyond being a useful aid to teaching and learning the core modeling skills needed for mathematical biology, is to encourage students to think deeply and clearly about the meaning of mathematics in science and to learn significant research methods. Most importantly, it is hoped that students will experience some of the excitement of doing research. Features Minimal pre-requisites beyond a solid background in calculus, such as a calculus I course. Suitable for upper division mathematics and sciences students and graduate-level biology students. Provides sample MATLAB codes and instruction in Appendices along with datasets available on https://bit.ly/3fcLF3D
Download or read book Mathematical Methods of Population Biology written by Frank Charles Hoppensteadt and published by Cambridge University Press. This book was released on 1982-02-26 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to mathematical methods used in the study of population phenomena including models of total population and population age structure, models of random population events presented in terms of Markov chains, and methods used to uncover qualitative behavior of more complicated difference equations.
Download or read book An Introduction to Undergraduate Research in Computational and Mathematical Biology written by Hannah Callender Highlander and published by Springer Nature. This book was released on 2020-02-17 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Speaking directly to the growing importance of research experience in undergraduate mathematics programs, this volume offers suggestions for undergraduate-appropriate research projects in mathematical and computational biology for students and their faculty mentors. The aim of each chapter is twofold: for faculty, to alleviate the challenges of identifying accessible topics and advising students through the research process; for students, to provide sufficient background, additional references, and context to excite students in these areas and to enable them to successfully undertake these problems in their research. Some of the topics discussed include: • Oscillatory behaviors present in real-world applications, from seasonal outbreaks of childhood diseases to action potentials in neurons • Simulating bacterial growth, competition, and resistance with agent-based models and laboratory experiments • Network structure and the dynamics of biological systems • Using neural networks to identify bird species from birdsong samples • Modeling fluid flow induced by the motion of pulmonary cilia Aimed at undergraduate mathematics faculty and advanced undergraduate students, this unique guide will be a valuable resource for generating fruitful research collaborations between students and faculty.
Download or read book Introduction to Mathematical Biology written by Ching Shan Chou and published by Springer. This book was released on 2016-04-27 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on a one semester course that the authors have been teaching for several years, and includes two sets of case studies. The first includes chemostat models, predator-prey interaction, competition among species, the spread of infectious diseases, and oscillations arising from bifurcations. In developing these topics, readers will also be introduced to the basic theory of ordinary differential equations, and how to work with MATLAB without having any prior programming experience. The second set of case studies were adapted from recent and current research papers to the level of the students. Topics have been selected based on public health interest. This includes the risk of atherosclerosis associated with high cholesterol levels, cancer and immune interactions, cancer therapy, and tuberculosis. Readers will experience how mathematical models and their numerical simulations can provide explanations that guide biological and biomedical research. Considered to be the undergraduate companion to the more advanced book "Mathematical Modeling of Biological Processes" (A. Friedman, C.-Y. Kao, Springer – 2014), this book is geared towards undergraduate students with little background in mathematics and no biological background.
Download or read book Mathematical Techniques for Biology and Medicine written by William Simon and published by Courier Corporation. This book was released on 2015-05-05 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Suitable for both graduate and undergraduate courses, this text recalls basic concepts of calculus and shows how problems can be formulated in terms of differential equations. Fully worked-out solutions to selected problems. Fourth edition.
Download or read book Mathematical Methods in Biology written by J. David Logan and published by John Wiley & Sons. This book was released on 2009-08-17 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: A one-of-a-kind guide to using deterministic and probabilistic methods for solving problems in the biological sciences Highlighting the growing relevance of quantitative techniques in scientific research, Mathematical Methods in Biology provides an accessible presentation of the broad range of important mathematical methods for solving problems in the biological sciences. The book reveals the growing connections between mathematics and biology through clear explanations and specific, interesting problems from areas such as population dynamics, foraging theory, and life history theory. The authors begin with an introduction and review of mathematical tools that are employed in subsequent chapters, including biological modeling, calculus, differential equations, dimensionless variables, and descriptive statistics. The following chapters examine standard discrete and continuous models using matrix algebra as well as difference and differential equations. Finally, the book outlines probability, statistics, and stochastic methods as well as material on bootstrapping and stochastic differential equations, which is a unique approach that is not offered in other literature on the topic. In order to demonstrate the application of mathematical methods to the biological sciences, the authors provide focused examples from the field of theoretical ecology, which serve as an accessible context for study while also demonstrating mathematical skills that are applicable to many other areas in the life sciences. The book's algorithms are illustrated using MATLAB®, but can also be replicated using other software packages, including R, Mathematica®, and Maple; however, the text does not require any single computer algebra package. Each chapter contains numerous exercises and problems that range in difficulty, from the basic to more challenging, to assist readers with building their problem-solving skills. Selected solutions are included at the back of the book, and a related Web site features supplemental material for further study. Extensively class-tested to ensure an easy-to-follow format, Mathematical Methods in Biology is an excellent book for mathematics and biology courses at the upper-undergraduate and graduate levels. It also serves as a valuable reference for researchers and professionals working in the fields of biology, ecology, and biomathematics.
Download or read book A Primer in Mathematical Models in Biology written by Lee A. Segel and published by SIAM. This book was released on 2013-01-01 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook introduces differential equations, biological applications, and simulations and emphasizes molecular events (biochemistry and enzyme kinetics), excitable systems (neural signals), and small protein and genetic circuits. A Primer on Mathematical Models in Biology will appeal to readers because it grew out of a course that the popular and highly respected applied mathematician Lee Segel taught at the Weizmann Institute and it represents his unique perspective; combines clear and useful mathematical methods with applications that illustrate the power of such tools; and includes many exercises in reasoning, modeling, and simulations.
Download or read book The Boundary Function Method for Singular Perturbed Problems written by Adelaida B. Vasil'eva and published by SIAM. This book was released on 1995-01-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book published in English devoted solely to the boundary function method, which is one of the asymptotic methods. This method provides an effective and simple way to obtain asymptotic approximations for the solutions of certain ordinary and partial differential equations containing small parameters in front of the highest derivatives. These equations, called singularly perturbed equations, are often used in modeling. In addition to numerous examples, the book includes discussions on singularly perturbed problems from chemical kinetics and heat conduction, semiconductor device modeling, and mathematical biology. The book also contains a variety of original ideas and explicit calculations previously available only in journal literature, as well as many concrete applied problems illustrating the boundary function method algorithms. Quite general asymptotic results described in the book are rigorous in the sense that, along with the asymptotic algorithms, in most cases the theorems on estimation of the remainder terms are presented. A survey of results of Russian mathematicians on the subject is provided; many of these results are not well known in the West. Based on the Russian edition of the textbook by Vasil'eva and Butuzov, this American edition, prepared by Kalachev, differs in many aspects. The text of the book has been revised substantially, some new material has been added to every chapter, and more examples, exercises, and new references on asymptotic methods and their applications have been included.
Download or read book Biology in Time and Space written by James P. Keener and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modeling Life written by Alan Garfinkel and published by Springer. This book was released on 2017-09-06 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?
Download or read book Mathematical Biology written by James D. Murray and published by Springer Science & Business Media. This book was released on 2007-06-12 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Biology is a richly illustrated textbook in an exciting and fast growing field. Providing an in-depth look at the practical use of math modeling, it features exercises throughout that are drawn from a variety of bioscientific disciplines - population biology, developmental biology, physiology, epidemiology, and evolution, among others. It maintains a consistent level throughout so that graduate students can use it to gain a foothold into this dynamic research area.
Download or read book Stochastic Processes Multiscale Modeling and Numerical Methods for Computational Cellular Biology written by David Holcman and published by Springer. This book was released on 2017-10-04 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the modeling and mathematical analysis of stochastic dynamical systems along with their simulations. The collected chapters will review fundamental and current topics and approaches to dynamical systems in cellular biology. This text aims to develop improved mathematical and computational methods with which to study biological processes. At the scale of a single cell, stochasticity becomes important due to low copy numbers of biological molecules, such as mRNA and proteins that take part in biochemical reactions driving cellular processes. When trying to describe such biological processes, the traditional deterministic models are often inadequate, precisely because of these low copy numbers. This book presents stochastic models, which are necessary to account for small particle numbers and extrinsic noise sources. The complexity of these models depend upon whether the biochemical reactions are diffusion-limited or reaction-limited. In the former case, one needs to adopt the framework of stochastic reaction-diffusion models, while in the latter, one can describe the processes by adopting the framework of Markov jump processes and stochastic differential equations. Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology will appeal to graduate students and researchers in the fields of applied mathematics, biophysics, and cellular biology.
Download or read book Singular Perturbations written by Elena Shchepakina and published by Springer. This book was released on 2014-10-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: These lecture notes provide a fresh approach to investigating singularly perturbed systems using asymptotic and geometrical techniques. It gives many examples and step-by-step techniques, which will help beginners move to a more advanced level. Singularly perturbed systems appear naturally in the modelling of many processes that are characterized by slow and fast motions simultaneously, for example, in fluid dynamics and nonlinear mechanics. This book’s approach consists in separating out the slow motions of the system under investigation. The result is a reduced differential system of lesser order. However, it inherits the essential elements of the qualitative behaviour of the original system. Singular Perturbations differs from other literature on the subject due to its methods and wide range of applications. It is a valuable reference for specialists in the areas of applied mathematics, engineering, physics, biology, as well as advanced undergraduates for the earlier parts of the book, and graduate students for the later chapters.
Download or read book Mathematics of Biology written by Mimmo Iannelli and published by Springer Science & Business Media. This book was released on 2011-06-04 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: K.L. Cooke: Delay differential equations.- J.M. Cushing: Volterra integrodifferential equations in population dynamics.- K.P. Hadeler: Diffusion equations in biology.- S. Hastings: Some mathematical problems arising in neurobiology.- F.C. Hoppensteadt: Perturbation methods in biology.- S.O. Londen: Integral equations of Volterra type.
Download or read book Mathematical Models in Biology written by Elizabeth Spencer Allman and published by Cambridge University Press. This book was released on 2004 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This introductory textbook on mathematical biology focuses on discrete models across a variety of biological subdisciplines. Biological topics treated include linear and non-linear models of populations, Markov models of molecular evolution, phylogenetic tree construction, genetics, and infectious disease models. The coverage of models of molecular evolution and phylogenetic tree construction from DNA sequence data is unique among books at this level. Computer investigations with MATLAB are incorporated throughout, in both exercises and more extensive projects, to give readers hands-on experience with the mathematical models developed. MATLAB programs accompany the text. Mathematical tools, such as matrix algebra, eigenvector analysis, and basic probability, are motivated by biological models and given self-contained developments, so that mathematical prerequisites are minimal.
Download or read book Mathematical Models in Biology written by Leah Edelstein-Keshet and published by . This book was released on 1988 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major aim of this book is to present instances of interaction between two major disciplines, biology and mathematics. The goal has been that of addressing a fairly wide audience. Biology students will find this text useful as a summary of modern mathematical methods currently used in modelling, and furthermore, applied mathematics students may benefit from examples of applications of mathematics to real-life problems. As little background as possible has been assumed throughout the book: prerequisites are basic calculus so that undergraduate students, as well as beginning graduate students, will find most of the material accessible.
