Download or read book METHODS FOR ASSESSING THE EFFECTS OF MIXTURES OF CHEMICALS SCOPE 30 written by VB. VOUK and published by . This book was released on 1987 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mixture Toxicity written by Cornelis A. M. van Gestel and published by CRC Press. This book was released on 2016-04-19 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an
Download or read book Methods to Assess the Effects of Chemicals on Ecosystems written by Rick A. Linthurst and published by . This book was released on 1995-10-12 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assesses the risks and estimates the injurious effects of both man-made and naturally-occurring chemicals on the ecological species that make up large complex ecosystems. Evaluates current knowledge of ecotoxicology and related testing methods, taking into account the potentials and limitations of current models and approaches. Other topics include methods of assessing the effects of chemicals on fresh waters, soils and forests; estuarine and near-coastal water organisms; arid and semi-arid ecosystems; aquatic and terrestrial wildlife and more.
Download or read book Ecological Risk Assessment written by Glenn W. Suter II and published by CRC Press. This book was released on 1992-10-23 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, environmental scientists have been required to perform a new type of assessment-ecological risk assessment. This is the first book that explains how to perform ecological risk assessments and gives assessors access to the full range of useful data, models, and conceptual approaches they need to perform an accurate assessment. It explains how ecological risk assessment relates to more familiar types of assessments. It also shows how to organize and conduct an ecological risk assessment, including defining the source, selecting endpoints, describing the relevant features of the receiving environment, estimating exposure, estimating effects, characterizing the risks, and interacting with the risk manager. Specific technical topics include finding and selecting toxicity data; statistical and mathematical models of effects on organisms, populations, and ecosystems; estimation of chemical fate parameters; modeling of chemical transport and fate; estimation of chemical uptake by organisms; and estimation, propagation, and presentation of uncertainty. Ecological Risk Assessment also covers conventional risk assessments, risk assessments for existing contamination, large scale problems, exotic organisms, and risk assessments based on environmental monitoring. Environmental assessors at regulatory agencies, consulting firms, industry, and government labs need this book for its approaches and methods for ecological risk assessment. Professors in ecology and other environmental sciences will find the book's practical preparation useful for classroom instruction. Environmental toxicologists and chemists will appreciate the discussion of the utility for risk assessment of particular toxicity tests and chemical determinations.
Download or read book Scientific Methodologies for the Assessment of Combined Effects of Chemicals a Survey and Literature Review written by and published by . This book was released on 2015 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposure of humans and wildlife to chemicals via food, consumer products, the environment etc. can imply exposure to an infinite number of different combinations of chemicals in mixtures. It is practically impossible to test all these possible mixtures experimentally and it is therefore needed to find smart strategies to assess the potential hazards using new tools that rely less on in vivo testing and incorporate instead alternative experimental and computational tools. In this report the current state of the art for the application of these alternative tools for assessing the hazard of chemical mixtures is briefly reviewed. The focus is hereby on the adverse outcome pathway (AOP) concept, in vitro methods, omics techniques, in silico approaches such as quantitative structure activity relationships (QSARs) and read-across, toxicokinetic and dynamic energy budget (DEB) modelling, and on integrated approaches to testing and assessment (IATA).^Furthermore, an expert survey was performed to collect up to date information and experience on the current use of different approaches for assessing human and environmental health risks from exposure to chemical mixtures, with a view to informing the development of a consistent assessment approach. An online survey was performed among experts in the field of combined exposure assessment in the period of January to March 2014, addressing both, human health and environmental risk assessment. Fiftyeight experts from 21 countries, different stakeholder groups and sectors of legislation participated in the survey. The main sectors where most experience is already gained in assessing mixtures are in the area of plant protection products and chemicals under REACH. These were also rated highest regarding the priority for performing mixture assessments.^Experts have experience with the whole mixture as well as the componentbased approaches applying them to both, intentional and unintentional mixtures. Mostly concentration addition (CA) based methods are used for predicting mixture effects. Regarding the use of novel and alternative tools in the risk assessment of mixtures, expert opinions are split between those applying them (often more in a research context) and those that generally think these tools are valuable but their use is currently limited because of lack of guidance, lack of data, or lack of expertise. A general need for clear guidance for combined exposure assessments was identified. Overall, a high potential in applying novel tools and scientific methodologies for the assessment of chemical mixtures can be identified. They allow deriving meaningful information on individual mixture components or whole mixtures, enabling a better understanding of the underlying mechanisms of mixture effects.^Their main strengths lie in their integrated use and smart combination to put different aspects regarding the hazard from combined exposure to multiple chemicals into context. In order to benefit from these tools in the hazard assessment of mixtures, more guidance on their use is needed to facilitate a more widespread application.
Download or read book Ecotoxicology of Organic Contaminants written by Eros Bacci and published by CRC Press. This book was released on 1993-11-24 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an integrated approach to understanding environmental contamination problems through the use of techniques from environmental chemistry, toxicology, ecology, and ecotoxicology. Basing much of his information on his 21 years of experience in the field, the author proposes innovative strategies for studying the environmental fate of contaminants, evaluating the effects, and producing scientific criteria for environmental safety. The book is clearly written, with all terms defined and equations explained with examples of their application. Weak points in the present knowledge are pointed out and discussed. An extensive list of references is provided for individuals who wish to delve deeper into the subject.
Download or read book Applied Ecotoxicology written by Johann F. Moltmann and published by CRC Press. This book was released on 2020-09-10 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book illustrates the complex nature of ecotoxicological issues, using pesticides as an example. It focuses on the assessment and monitoring of the amounts of pollutants in the environment and the subsequent damage. The text provides the basic information and methodology to help the reader determine the extent of ecological damage caused by a given substance. Legislatures in industrialized countries have taken the initiative in dealing with these issues by formulating new priorities for environmental protection. Applied Ecotoxicology describes these regulatory efforts, which are separated by their two distinct objectives: those that seek to expand the scope of protection against the pollutants' negative impacts, and those shifting the level of investigation from the individual to the ecosystem. Pollutants are only one of a number of different environmental factors to which organisms are exposed. Their impact in the field is presented in the context of other forms of human intervention in the environment. The increasing use of pesticides in tropical regions, a growing ecotoxicological concern in these countries, is also discussed.
Download or read book The Silicon Cycle written by Venugopalan Ittekkot and published by Island Press. This book was released on 2012-09-26 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Silicon is among the most abundant elements on earth. It plays a key but largely unappreciated role in many biogeochemical processes, including those that regulate climate and undergird marine food webs. The Silicon Cycle is the first book in more than 20 years to present a comprehensive overview of the silicon cycle and issues associated with it. The book summarizes the major outcomes of the project Land-Ocean Interactions: Silica Cycle, initiated by the Scientific Community on Problems of the Environment (SCOPE) of the International Council of Scientific Unions (ICSU). It tracks the pathway of silicon from land to sea and discusses its biotic and abiotic modifications in transit as well as its cycling in the coastal seas. Natural geological processes in combination with atmospheric and hydrological processes are discussed, as well as human perturbations of the natural controls of the silicon cycle.
Download or read book Ecotoxicology written by Frank Moriarty and published by Academic Press. This book was released on 1999-04-30 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecotoxicology, Third Edition discusses the ecological effects of pollutants: the ways in which ecosystems can be affected, and current attempts to predict and monitor such effects. The emphasis is on ecosystems; therefore toxicological approaches are critically assessed. Following a brief introduction to the principal characteristics of both pollutants and ecosystems, the various ecosystem components are considered in more detail. Populations, communities and gene pools are examined with an emphasis on the ways in which pollutants affect them specifically. The indirect effects of pollution are considered separately in a new chapter with particular attention paid to the mechanisms and biological effects of global warming. A discussion of the methods used to predict and to monitor the effects of pollutants, some illustrative examples of pollution problems and a final summary discussion, complete the book. - A classic proven by its second edition - Still the only book to properly integrate ecological principles with chemistry/biochemistry - Focuses on the interaction between ecology and toxicology - Designed for use by toxicologists with no ecology training, and for ecologists with no toxicology training - There is a new chapter on pollutants in habitats and global warming
Download or read book Methods for Assessing and Reducing Injury from Chemical Accidents written by Philippe Bourdeau and published by . This book was released on 1989-08-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Papers from a workshop held in New Delhi, Jan. 27 - Feb. 2, 1987.
Download or read book Statistical Analysis of Ecotoxicity Studies written by John W. Green and published by John Wiley & Sons. This book was released on 2018-07-04 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the issues relevant to the design, analysis, and interpretation of toxicity studies that examine chemicals for use in the environment Statistical Analysis of Ecotoxicity Studies offers a guide to the design, analysis, and interpretation of a range of experiments that are used to assess the toxicity of chemicals. While the book highlights ecotoxicity studies, the methods presented are applicable to the broad range of toxicity studies. The text contains myriad datasets (from laboratory and field research) that clearly illustrate the book's topics. The datasets reveal the techniques, pitfalls, and precautions derived from these studies. The text includes information on recently developed methods for the analysis of severity scores and other ordered responses, as well as extensive power studies of competing tests and computer simulation studies of regression models that offer an understanding of the sensitivity (or lack thereof) of various methods and the quality of parameter estimates from regression models. The authors also discuss the regulatory process indicating how test guidelines are developed and review the statistical methodology in current or pending OECD and USEPA ecotoxicity guidelines. This important guide: Offers the information needed for the design and analysis to a wide array of ecotoxicity experiments and to the development of international test guidelines used to assess the toxicity of chemicals Contains a thorough examination of the statistical issues that arise in toxicity studies, especially ecotoxicity Includes an introduction to toxicity experiments and statistical analysis basics Includes programs in R and excel Covers the analysis of continuous and Quantal data, analysis of data as well as Regulatory Issues Presents additional topics (Mesocosm and Microplate experiments, mixtures of chemicals, benchmark dose models, and limit tests) as well as software Written for directors, scientists, regulators, and technicians, Statistical Analysis of Ecotoxicity Studies provides a sound understanding of the technical and practical issues in designing, analyzing, and interpreting toxicity studies to support or challenge chemicals for use in the environment.
Download or read book Anticarcinogenesis and Radiation Protection 2 written by O.F. Nygaard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dramatic decrease in the incidence of stomach cancer in industrialized countries during the past 50 years, which is yet to be fully explained, and the observation that carcinogenesis in laboratory animals can be inhibited by antioxidants, retinoids, and caloric restriction, among other influences, challenge us to press on in the search for practical means to prevent cancer. It is in relation to this goal that the studies summarized in this book have special significance. This book is based on the invited and contributed papers presented at the Third Internationai Conference on Anticarcinogenesis and Radiation Protection, held on October 15-21, 1989, in Dubrovnik, Yugoslavia. They cover a broad range of investigations into the mechanisms and inhibition of carcinogenesis. In keeping with recent advances in our understanding of the importance of oncogenes and tumor-suppressor genes in carcinogenesis, many of the reports focus on mutations and related changes at the level of DNA. At the same time, however, other reports deal with nutritional, immunological, endocrinological, and epidemiological aspects. In all, the various reports address carcinogenesis and its inhibition at virtually every level of biological organization. Included in this compendium are timely reviews of diverse and promising research strategies for cancer prevention, as pursued by investigators in different parts of the world. The Organizers of the Conference are grateful to the many scientists who have contributed to the volume, as well as to the sponsors of the Conference, without whose generous support this book would not have been possible.
Download or read book Sustainability Indicators written by Tomás Hák and published by Island Press. This book was released on 2012-09-26 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the concept of sustainability has been widely embraced, it has been only vaguely defined and is exceedingly difficult to measure. Sustainability indicators are critical to making the broad concept of sustainability operational by providing specific measures by which decision makers and the public can judge progress. Sustainability Indicators defines the present state of the art in indicator development. It presents a comprehensive assessment of the science behind various indicators, while placing special emphasis on their use as communications tools. The contributors draw on their experience as academics and practitioners to describe the conceptual challenges to measuring something as complex as sustainability at local, regional, national, and global scales. The book also reviews existing indicators to assess how they could be better employed, considering which indicators are overused and which have been underutilized. Sustainability Indicators will help planners and policy makers find indicators that are ready for application and relevant to their needs, and will help researchers identify the unresolved issues where progress is most urgently needed. All readers will find advice as to the most effective ways to use indicators to support decision making.
Download or read book The Global Carbon Cycle written by Christopher B. Field and published by Island Press. This book was released on 2012-09-26 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: While a number of gases are implicated in global warming, carbon dioxide is the most important contributor, and in one sense the entire phenomena can be seen as a human-induced perturbation of the carbon cycle. The Global Carbon Cycle offers a scientific assessment of the state of current knowledge of the carbon cycle by the world's leading scientists sponsored by SCOPE and the Global Carbon Project, and other international partners. It gives an introductory over-view of the carbon cycle, with multidisciplinary contributions covering biological, physical, and social science aspects. Included are 29 chapters covering topics including: an assessment of carbon-climate-human interactions; a portfolio of carbon management options; spatial and temporal distribution of sources and sinks of carbon dioxide; socio-economic driving forces of emissions scenarios. Throughout, contributors emphasize that all parts of the carbon cycle are interrelated, and only by developing a framework that considers the full set of feedbacks will we be able to achieve a thorough understanding and develop effective management strategies. The Global Carbon Cycle edited by Christopher B. Field and Michael R. Raupach is part of the Rapid Assessment Publication series produced by the Scientific Committee on Problems of the Environment (SCOPE), in an effort to quickly disseminate the collective knowledge of the world's leading experts on topics of pressing environmental concern.
Download or read book Methods for Assessing Exposure of Human and Non human Biota written by Robert G. Tardiff and published by . This book was released on 1991-09-27 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: A report on the risks to human and non-human life associated with environmental chemicals. Summarizes contributions from highly qualified people throughout the world and provides a critical and collective evaluation of approaches to chemical exposure assessment. Risk assessment is approached in the following ways: direct evaluation of exposure to the organism through consumption of food, water or air; consideration of movement of chemicals from distant sources to point of exposure including possible alteration enroute; analysis of exposed tissues.
Download or read book Resilience and the Behavior of Large Scale Systems written by Lance H. Gunderson and published by Island Press. This book was released on 2012-06-22 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists and researchers concerned with the behavior of large ecosystems have focused in recent years on the concept of "resilience." Traditional perspectives held that ecological systems exist close to a steady state and resilience is the ability of the system to return rapidly to that state following perturbation. However beginning with the work of C. S. Holling in the early 1970s, researchers began to look at conditions far from the steady state where instabilities can cause a system to shift into an entirely different regime of behavior, and where resilience is measured by the magnitude of disturbance that can be absorbed before the system is restructured. Resilience and the Behavior of Large-Scale Systems examines theories of resilience and change, offering readers a thorough understanding of how the properties of ecological resilience and human adaptability interact in complex, regional-scale systems. The book addresses the theoretical concepts of resilience and stability in large-scale ecosystems as well as the empirical application of those concepts in a diverse set of cases. In addition, it discusses the practical implications of the new theoretical approaches and their role in the sustainability of human-modified ecosystems. The book begins with a review of key properties of complex adaptive systems that contribute to overall resilience, including multiple equlibria, complexity, self-organization at multiple scales, and order; it also presents a set of mathematical metaphors to describe and deepen the reader's understanding of the ideas being discussed. Following the introduction are case studies that explore the biophysical dimensions of resilience in both terrestrial and aquatic systems and evaluate the propositions presented in the introductory chapters. The book concludes with a synthesis section that revisits propositions in light of the case studies, while an appendix presents a detailed account of the relationship between return times for a disturbed system and its resilienc. In addition to the editors, contributors include Stephen R. Carpenter, Carl Folke, C. S. Holling, Bengt-Owe Jansson, Donald Ludwig, Ariel Lugo, Tim R. McClanahan, Garry D. Peterson, and Brian H. Walker.
Download or read book Biodiversity Change and Human Health written by Osvaldo E. Sala and published by Island Press. This book was released on 2012-09-26 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biodiversity Change and Human Health brings together leading experts from the natural science and social science realms as well as the medical community to explore the explicit linkages between human-driven alterations of biodiversity and documented impacts of those changes on human health. The book utilizes multidisciplinary approaches to explore and address the complex interplay between natural biodiversity and human health and well-being. The five parts examine health trade-offs between competing uses of biodiversity (highlighting synergistic situations in which conservation of natural biodiversity actually promotes human health and well-being); relationships between biodiversity and quality of life that have developed over ecological and evolutionary time; the effects of changing biodiversity on provisioning of ecosystem services, and how they have affected human health; the role of biodiversity in the spread of infectious disease; native biodiversity as a resource for traditional and modern medicine Biodiversity Change and Human Health synthesizes our current understanding and identifies major gaps in knowledge as it places all aspects of biodiversity and health interactions within a common framework. Contributors explore potential points of crossover among disciplines (both in ways of thinking and of specific methodologies) that could ultimately expand opportunities for humans to both live sustainably and enjoy a desirable quality of life.
