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Book Methodology of the Evaluation of Psychotropic Drugs

Download or read book Methodology of the Evaluation of Psychotropic Drugs written by Otto Benkert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea of placebo-controlled drug trials and the advent of test statistics during the first part of this century were the major milestones in the establishment of a convincing methodology for demonstrating the efficacy of treatments. The first tricyclic and neuroleptic drugs were tested for their efficacy in psychiatric disorders along the lines of these methodological developments, but subsequent trials with psychotropic drugs did not adhere to these principles to the same extent because it became difficult to justify placebo-controlled trials once effective treatments had been established. Consequently, the second generation of an tidepressants and neuroleptics (since the early 1960s) were mainly tested, in Europe at least, in samples of patients using trials controlled by standard treatment only, and the methodological basis of these second generation trials became fragile, as will be demonstrated by several papers in this book. This development did not provoke much discussion until recently, when scientific and administrative interest in the methodology of the evaluation of psychotropic drugs increased substantially. A series of factors contribute to the growing interest in the standards of psychotropic drug trials: 1. The proportion of psychiatric patients resistant to treatment is growing; the efficacy of well-established forms of treatment therefore seems to be limited. 2. A series of psychotropic drugs were withdrawn from the market, mainly because they caused serious side effects. The efficacy and safety ofthese drugs had previously been demonstrated in drug trials, which raised the question whether the drug trials carried out were well-designed.

Book Clinical Evaluation of Psychotropic Drugs

Download or read book Clinical Evaluation of Psychotropic Drugs written by Robert F. Prien and published by Raven Press (ID). This book was released on 1994 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: A source book in clinical methods for the understanding of psycho- pharmacologic agents and clinical evaluation of drugs in the treatment of mental disorder, produced in association with the National Institute of Mental health and the American College of Neuropsychopharmacology. The volume consists of three main sections. The first addresses the historical context of clinical psychopharmacologic research and guidelines and the decision process involved in drug development and evaluation. Section II addresses broad developments and issues for clinical methodology, providing guidance in research principles, study design and implementation, reporting of study findings, and ethical considerations involving drug evaluations. Section III provides methodologic developments and recommendations for research involving specific patient populations. Annotation copyright by Book News, Inc., Portland, OR

Book Clinical Evaluation of Psychotropic Drugs for Psychiatric Disorders

Download or read book Clinical Evaluation of Psychotropic Drugs for Psychiatric Disorders written by World Health Organization and published by Seattle ; Toronto : Hogrefe & Huber Publishers. This book was released on 1993 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychotropic medications have been dramatically successful over the since the 1950s, but severe problems remain. The World Health Organization (WHO) has a legal responsibility to review these drugs, estimate their benefit/risk ratio, help ensure their proper prescription and recommend which ones require international controls. This book utilizes the experience of the WHO to provide information about how such drugs should be evaluated, such as the planning, executing, monitoring, analyzing, interpreting and reporting involved with correctly making such evaluations. Subjects range from the evaluation of drugs from primary studies in healthy volunteers to the longitudinal study of drugs in routine use. Further chapters examine special issues in the evaluations of drug effects upon children and the elderly. There is also a section on study design and a final brief chapter on some transcultural issues.

Book Clinical Evaluation of Psychotropic Drugs for Psychiatric Disorders

Download or read book Clinical Evaluation of Psychotropic Drugs for Psychiatric Disorders written by Paul Grof and published by Hogrefe & Huber Publishing. This book was released on 1993 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Drug Discovery and Evaluation  Pharmacological Assays

Download or read book Drug Discovery and Evaluation Pharmacological Assays written by Hans Vogel and published by Springer Science & Business Media. This book was released on 2007-10-30 with total page 2118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this successful reference offers both cutting-edge and classic pharmacological methods. Thoroughly revised and expanded to two volumes, it offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Every chapter has been updated, and numerous assays have been added. Each of the more than 1,000 assays comprises a detailed protocol outlining purpose and rationale, and a critical assessment of the results and their pharmacological and clinical relevance.

Book Psychopharmacology Abstracts

Download or read book Psychopharmacology Abstracts written by and published by . This book was released on 1976 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Mental Disorders in Primary Care

Download or read book Mental Disorders in Primary Care written by Andre F. Carvalho and published by Oxford University Press. This book was released on 2017 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: An invaluable guide to psychiatric presentation, diagnosis and treatment in a primary care setting.

Book Methods of Behavior Analysis in Neuroscience

Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Book Drug Interactions in Psychiatry

Download or read book Drug Interactions in Psychiatry written by Domenic A. Ciraulo and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated for its Third Edition, this handbook provides complete, current, and easily accessible information on how psychotropic drugs interact with one another and with compounds used to treat non-psychiatric medical conditions. The book is organized for rapid reference, includes numerous tables, and offers guidelines for managing adverse effects. The Third Edition includes an adverse drug effects table in the appendix section, tables on receptor binding and dosing, and the latest information on drugs of abuse and chemical dependence. This edition also includes drug-food interactions for each drug category and interactions of psychotropic drugs with HIV medications.

Book Psychotropic Drug Information Handbook

Download or read book Psychotropic Drug Information Handbook written by Matthew A. Fuller and published by Lexi-Comp. This book was released on 2005 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Manual of Clinical Psychopharmacology

Download or read book Manual of Clinical Psychopharmacology written by Alan F. Schatzberg and published by American Psychiatric Publishing. This book was released on 1991 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discussing the use of various types of drugs in the treatment of psychiatric patients, this volume covers such topics as anti-depressants, mood stabilizers, hypnotics and anti-psychotics drugs. It also looks at combination treatments and pharmacotherapy of chemical dependence.

Book International Directory of Investigators in Psychopharmacology

Download or read book International Directory of Investigators in Psychopharmacology written by National Institute of Mental Health (U.S.) and published by . This book was released on 1972 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Guidelines for the Control of Narcotic and Psychotropic Substances

Download or read book Guidelines for the Control of Narcotic and Psychotropic Substances written by World Health Organization and published by World Health Organization. This book was released on 1984 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Polypharmacy in Psychiatry

Download or read book Polypharmacy in Psychiatry written by S. Nassir Ghaemi and published by CRC Press. This book was released on 2002-05-06 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical reference examines the advantages and disadvantages of polypharmacy in psychiatry, and provides up-to-date clinical guidelines on the appropriate use of combinations of pharmacological therapy in major psychiatric disorders-including multidisciplinary approaches to treatment, such as social work and psychopharmacology, and an examina

Book NeuroPsychopharmacotherapy

Download or read book NeuroPsychopharmacotherapy written by Peter Riederer and published by Springer Nature. This book was released on 2022-11-04 with total page 4652 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a reference guide describing the current status of medication in all major psychiatric and neurological indications, together with comparisons of pharmacological treatment strategies in clinical settings in Europe, USA, Japan and China. In addition, it highlights herbal medicine as used in China and Japan, as well as complementary medicine and nutritional aspects. This novel approach offers international readers a global approach in a single dedicated publication and is also a valuable resource for anyone interested in comparing treatments for psychiatric disorders in three different cultural areas. There are three volumes devoted to Basic Principles and General Aspects, offering a general overview of psychopharmacotherapy (Vol. 1); Classes, Drugs and Special Aspects covering the role of psychotropic drugs in the field of psychiatry and neurology (Vol. 2) and Applied Psychopharmacotherapy focusing on applied psychopharmacotherapy (Vol. 3). These books are invaluable to psychiatrists, neurologists, neuroscientists, medical practitioners and clinical psychologists.

Book The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia

Download or read book The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia written by American Psychiatric Association and published by American Psychiatric Pub. This book was released on 2016 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The guideline offers clear, concise, and actionable recommendation statements to help clinicians to incorporate recommendations into clinical practice, with the goal of improving quality of care. Each recommendation is given a rating that reflects the level of confidence that potential benefits of an intervention outweigh potential harms.

Book Encyclopedia of Psychopharmacology

Download or read book Encyclopedia of Psychopharmacology written by Ian Stolerman and published by Springer Science & Business Media. This book was released on 2010-07-31 with total page 1433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a broad overview of the central topics and issues in psychopharmacology, biological psychiatry and behavioral neurosciences, with information about developments in the field, including novel drugs and technologies. The more than 2000 entries are written by leading experts in pharmacology and psychiatry and comprise in-depth essays, illustrated with full-color figures, and are presented in a lucid style.