Download or read book Metallofoldamers written by Galia Maayan and published by John Wiley & Sons. This book was released on 2013-01-18 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metallofoldamers are oligomers that fold into three-dimensional structures in a controlled manner upon coordination with metal ions. Molecules in this class have shown an impressive ability to form single-handed helical structures and other three-dimensional architectures. Several metallofoldamers have been applied as sensors due to their selective folding when binding to a specific metal ion, while others show promise for applications as responsive materials on the basis of their ability to fold and unfold upon changes in the oxidation state of the coordinated metal ion, and as novel catalysts. Metallofoldamers: From Helicates to Biomimetic Architectures describes the variety of interactions between oligomers and metal species, with a focus on non-natural synthetic molecules. Topics covered include: the major classes of foldamers and their folding driving force metalloproteins and metalloenzymes helicates: self-assembly, structure and applications abiotic metallo-DNA metallo-PNA and iDNA metallopeptides interactions of biomimetic oligomers with metal ions applications of metallofoldamers
Download or read book Comprehensive Supramolecular Chemistry II written by George W. Gokel and published by Elsevier. This book was released on 2017-06-22 with total page 4627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Supramolecular Chemistry II, Second Edition, Nine Volume Set is a ‘one-stop shop’ that covers supramolecular chemistry, a field that originated from the work of researchers in organic, inorganic and physical chemistry, with some biological influence. The original edition was structured to reflect, in part, the origin of the field. However, in the past two decades, the field has changed a great deal as reflected in this new work that covers the general principles of supramolecular chemistry and molecular recognition, experimental and computational methods in supramolecular chemistry, supramolecular receptors, dynamic supramolecular chemistry, supramolecular engineering, crystallographic (engineered) assemblies, sensors, imaging agents, devices and the latest in nanotechnology. Each section begins with an introduction by an expert in the field, who offers an initial perspective on the development of the field. Each article begins with outlining basic concepts before moving on to more advanced material. Contains content that begins with the basics before moving on to more complex concepts, making it suitable for advanced undergraduates as well as academic researchers Focuses on application of the theory in practice, with particular focus on areas that have gained increasing importance in the 21st century, including nanomedicine, nanotechnology and medicinal chemistry Fully rewritten to make a completely up-to-date reference work that covers all the major advances that have taken place since the First Edition published in 1996
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2008 with total page 1006 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis of Two dimensional Scaffolds and Metallofoldamers written by Zhenzhen Dong and published by ProQuest. This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A strategy for creating two-dimensional, ordered arrays of linear, conjugated organic molecules on polyimide scaffolds is described. The design takes advantage of the enforcement of consecutive 90° twist angles along the polyimide backbone. Rod-shaped conjugated molecules are held parallel and in the same plane on the scaffolds, and have optical properties similar to those of monomeric analogues. As supporting evidence for the structure of the polymers, a series of model compounds were synthesized and characterized by x-ray crystallography. The polymeric materials are soluble in common organic solvents and have been characterized by 1 H NMR, 13 C NMR, MALDI-TOF, Gel Permeation Chromatography (GPC) and UV-vis spectroscopy. The average molecular weight was determined by end group analysis. Kinetic VT-NMR study of the model compound shows that single bond rotate through the polyimide backbone only at high temperature (>90°C). Because rotation is slow at room temperature, it is expected that these polymers will serve as excellent scaffolds for aligning second order non-linear optical materials, as NLO chromophores can be poled at high temperature, but will not realign at room temperature. Ni-salophen derived foldamers were designed, synthesized and studied. The absolute sense of helicity is effectively controlled via secondary sphere chirality, through which peripheral stereocenters control the asymmetric environment. Three-center hydrogen bonds and steric interactions were utilized to bias the absolute sense of helicity. The strong bias was supported by chiroptical data and low temperature NMR studies. The helical structure in solid state was confirmed by x-ray crystallography and the solution geometry was confirmed by a series of NMR spectroscopic studies. Chiral metal-salen complexes are widely employed as asymmetric catalysts and helicity has been proposed to play a role in asymmetric induction by metal salen catalysts. A tool for measuring the ability of chiral diamine to induce asymmetry in metal-salen complexes was developed. This was accomplished by juxtaposing competing elements of chirality within Ni(salen) complexes that are predisposed to fold. The chiral end group biases for the formation of the (M)-helix, whereas the diamine biases for the diastereomeric metallofoldamer of (P)-helicity. Spectroscopic and crystallographic studies of these complexes show that the trans -cyclohexanediamine is only a weak director of absolute helicity in Ni(salen) complexes. The bias of the diamine is completely overridden by the chiral end group. An implication of this study for asymmetric catalysis is that both helical diastereomers must be considered in any models that invoke helicity to explain asymmetric induction with chiral salens. To create metal salen-based foldamers that are appropriate for asymmetric catalysis, a small foldamer was designed and synthesized. The ends of this foldamer do not wrap. The complex retains the virtue of peripheral stereocenter control over catalyst helicity. A new steric interaction is created in the design to bias the absolute sense of helicity. The helical structure of the minimalist foldamer in solid state was confirmed by x-ray crystallography and the strong bias of absolute helicity in solution was determined by chiroptical data and low temperature NMR studies.
Download or read book Chirality in Supramolecular Assemblies written by F. Richard Keene and published by John Wiley & Sons. This book was released on 2017-01-03 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular chemistry deals with the organisation of molecules into defined assemblies using non-covalent interactions, including weaker and reversible interactions such as hydrogen bonds, and metal-ligand interactions. The aspect of stereochemistry within such chemical architectures, and in particular chirality, is of special interest as it impacts on considerations of molecular recognition, the development of functional materials, the vexed question of homochirality, nanoscale effects of interactions at interfaces, biocatalysis and enzymatic catalysis, and applications in organic synthesis. Chirality in Supramolecular Assemblies addresses many of these aspects, presenting a broad overview of this important and rapidly developing interdisciplinary field. Topics covered include: Origins of molecular and topological chirality Homochirogenesis Chirality in crystallinity Host-guest behavior Chiral influences in functional materials Chirality in network solids and coordination solids Aspects of chirality at interfaces Chirality in organic assemblies Chirality related to biocatalysis and enzymes in organic synthesis. This book is a valuable reference for researchers in the molecular sciences, materials science and biological science working with chiral supramolecular systems. It provides summaries and special insights by acknowledged international experts in the various fields.
Download or read book Middle Molecular Strategy written by Koichi Fukase and published by Springer Nature. This book was released on 2021-07-13 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights recently discovered aspects of “middle-size molecules,” focusing on (1) their unique bio-functions on the basis of derivatives and conjugates of natural products, saccharides, peptides, and nucleotides; (2) the synthesis of structurally complex natural products; (3) special synthetic methods for π-conjugated functional molecules; and (4) novel synthetic methods using flow chemistry. Given its scope, the book is of interest to industrial researchers and graduate students in the fields of organic chemistry, medicinal chemistry, and materials science.
Download or read book Biomimicry for Materials Design and Habitats written by Marjan Eggermont and published by Elsevier. This book was released on 2022-02-21 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomimicry for Materials, Design and Habitats: Innovations and Applications and is a survey of the recent work of recognized experts in a variety of fields who employ biomimicry and related paradigms to solve key problems of interest within design, science, technology, and society. Topics covered include innovations from biomimicry in materials, product design, architecture, and biological sciences. The book is a useful resource for educators, designers, researchers, engineers, and materials scientists, taking them from the theory behind biomimicry to real world applications. Living systems have evolved innovative solutions to challenges that humans face on a daily basis. Nonlinear multifunctional systems that have a symbiotic relationship with their environment are the domain of nature. Morphological solutions for buildings inspired by nature can be used for skins, surfaces, and structures to facilitate environmental adaptation of buildings to increase occupant comfort and reduce energy demands. Birds can teach us to produce novel structures, 3D printing can be informed by oysters and mussels, and mycelium may show us the way to fabricate new biocomposites in architecture. Therefore, it is in nature that we seek inspiration for the solutions to tomorrow's challenges. - Presents new directions in education and the various applications of biomimicry within industry, including bio-inspired entrepreneurship - Discusses the role of biomimicry in education, innovation, and product design - Covers applications in systems engineering and design, novel materials with applications in 3D printing, and bio-inspired architecture - Includes perspectives on sustainability detailing the role that bio-inspiration or biomimicry plays in sustainability
Download or read book Synergy in Supramolecular Chemistry written by Tatsuya Nabeshima and published by CRC Press. This book was released on 2014-12-18 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cooperative and synergistic chemical events have attracted significant attention from many researchers engaged in organic chemistry, inorganic chemistry, biological chemistry, polymer chemistry, medicinal chemistry, and other related materials sciences. Synergistic supramolecular systems could be developed to amplify the functions and integration o
Download or read book Bioorganometallic Chemistry written by Gérard Jaouen and published by John Wiley & Sons. This book was released on 2015-04-20 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date reference reflecting the significant advances and important breakthroughs made in this emerging discipline over the last decade. As such, the book provides an overview of the latest developments and future trends in the field, focusing on such applications as the development of potentially active organometallic drugs against incurable diseases, as well as in such areas as catalysis, energy, analytical chemistry, and imaging. The renowned editor, who established the term "bioorganometallics", and his international team of experts have put together a valuable resource for researchers in organometallic, inorganic, medicinal, and biochemistry.
Download or read book Advances in Physical Organic Chemistry written by and published by Academic Press. This book was released on 2021-11-22 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Physical Organic Chemistry, Volume 55, presents the latest reviews of recent work in physical organic chemistry. The book provides a valuable source of information that is ideal not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. The book's hallmark is its quantitative, molecular level understanding of phenomena across a diverse range of disciplines. Reviews the application of quantitative and mathematical methods to help readers understand chemical problems Provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry Covers organic, organometallic, bioorganic, enzymes and materials topics Presents the only regularly published resource for reviews in physical organic chemistry Written by authoritative experts who cover a wide range of topics that require a quantitative, molecular-level understanding of phenomena across a diverse range of disciplines
Download or read book Synthesis and Characterization of a Ru Coordinated Azobenzene Metallofoldamer written by Christina E. Forties and published by . This book was released on 2008 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Inspired by naturally occurring molecules that fold, twist and interact, the formation and conformation of molecular structure is a wide area of research in synthetic organic chemistry. In our group, Chenyang Tie found that extended oligomers with alternating pyridine-2,6-dicarboxamide and azobenzene units fold into M- and P-type helices in the solid state. Here, metallated complexes composed of oligomers with pyridine-2,6-dicarboxamide and azobenzene units were investigated. Monte Carlo conformational searching suggested that upon metallation of ortho-bis-azobenzene diimine oligomers with a [RuCl2(p-cymene)]2 complex, the molecules would adopt a low energy, helical structure. Syntheses of ortho- and meta- azobenzene diimine compounds, as well as the metallation of the diimnes, are described in this thesis. Product formation for one of the meta-mono azo metallated structures was suggested according to various spectroscopic methods, and the full characterization of this complex is also detailed. The focus of future work will be to synthesize extended metallofoldamers of the meta-mono azo diimine variety, to investigate the conformational properties of the metallated compounds and apply them towards functional applications such as molecular recognition or catalysis.
Download or read book Circularly Polarized Luminescence of Isolated Small Organic Molecules written by Tadashi Mori and published by Springer Nature. This book was released on 2020-04-13 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects all the latest advances in the leading research of the circularly polarized luminescence (CPL) of small organic molecules. Compared with that of lanthanide-based fluorophores, the research into the CPL of small organic molecules is still at the developmental stage for their relatively smaller dissymmetric factors, but has been a source of widespread attention recently. The book includes the state of the art of the discoveries in CPL organic molecules, such as helicenes, biaryls, cyclophanes, boron dipyrromethene dyes, and other chiral molecules, mostly in their isolated states, covering all possible chiral substances for future applications. This book also highlights the recent development of CPL instruments as well as time-resolved circular dichroism spectroscopy, to facilitate the further development and future design of CPL molecules.
Download or read book Protein Folding and Metal Ions written by Cláudio M. Gomes and published by CRC Press. This book was released on 2016-04-19 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of metal ions in protein folding and structure is a critical topic to a range of scientists in numerous fields, particularly those working in structural biology and bioinorganic chemistry, those studying protein folding and disease, and those involved in the molecular and cellular aspects of metals in biological systems. Protein Folding an
Download or read book Supramolecular Chemistry written by Jonathan W. Steed and published by John Wiley & Sons. This book was released on 2013-05-21 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular chemistry is ‘chemistry beyond the molecule’ - the chemistry of molecular assemblies and intermolecular bonds. It is one of today’s fastest growing disciplines, crossing a range of subjects from biological chemistry to materials science; and from synthesis to spectroscopy. Supramolecular Chemistry is an up-to-date, integrated textbook that tells the newcomer to the field everything they need to know to get started. Assuming little in the way of prior knowledge, the book covers the concepts behind the subject, its breadth, applications and the latest contemporary thinking in the area. It also includes coverage of the more important experimental and instrumental techniques needed by supramolecular chemists. The book has been thoroughly updated for this second edition. In addition to the strengths of the very popular first edition, this comprehensive new version expands coverage into a broad range of emerging areas. Clear explanations of both fundamental and nascent concepts are supplemented by up-to-date coverage of exciting emerging trends in the literature. Numerous examples and problems are included throughout the book. A system of “key references” allows rapid access to the secondary literature, and of course comprehensive primary literature citations are provided. A selection of the topics covered is listed below. Cation, anion, ion-pair and molecular host-guest chemistry Crystal engineering Topological entanglement Clathrates Self-assembly Molecular devices Dendrimers Supramolecular polymers Microfabrication Nanoparticles Chemical emergence Metal-organic frameworks Gels Ionic liquids Supramolecular catalysis Molecular electronics Polymorphism Gas sorption Anion-pinteractions Nanochemistry Supramolecular Chemistry is a must for both students new to the field and for experienced researchers wanting to explore the origins and wider context of their work. Review: "At just under 1000 pages, the second edition of Steed and Atwood's Supramolecular Chemistry is the most comprehensive overview of the area available in textbook form...highly recommended." —Chemistry World, August 2009
Download or read book Single Chain Polymer Nanoparticles written by José A. Pomposo and published by John Wiley & Sons. This book was released on 2017-08-18 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first book on this important and emerging topic presents an overview of the very latest results obtained in single-chain polymer nanoparticles obtained by folding synthetic single polymer chains, painting a complete picture from synthesis via characterization to everyday applications. The initial chapters describe the synthetics methods as well as the molecular simulation of these nanoparticles, while subsequent chapters discuss the analytical techniques that are applied to characterize them, including size and structural characterization as well as scattering techniques. The final chapters are then devoted to the practical applications in nanomedicine, sensing, catalysis and several other uses, concluding with a look at the future for such nanoparticles. Essential reading for polymer and materials scientists, materials engineers, biochemists as well as environmental chemists.
Download or read book Comprehensive Coordination Chemistry III written by and published by Elsevier. This book was released on 2021-07-29 with total page 6948 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Coordination Chemistry III describes the fundamentals of metal-ligand interactions, provides an overview of the systematic chemistry of this class of compounds, and details their importance in life processes, medicine, industry and materials science. This new edition spans across 9 volumes, 185 entries and 6600 printed pages. Comprehensive Coordination Chemistry III is not just an update of the second edition, it includes a significant amount of new content. In the descriptive sections 3-6, emphasis is placed upon material that has appeared in primary and secondary review literature since the previous edition published. The material in other sections is newly written, with an emphasis on modern aspects of coordination chemistry and the latest developments. The metal-ligand interaction is the link between the award of the 1913 Nobel Prize in Chemistry to Alfred Werner, the father of Coordination Chemistry, the 1987 prize for supramolecular chemistry and the 2016 award for molecular machines. The key role of coordination chemistry in the assembly of hierarchical nano- and micro-dimensioned structures lies at the core of these applications and so this Major Reference Work bridges several sub-disciplines of chemistry, thus targeting a truly interdisciplinary audience. Provides the go-to foundational resource on coordination chemistry research, providing insights into future directions of the field Written and edited by renowned academics and practitioners from various fields and regions this authoritative and interdisciplinary work is of interest to a large audience, including coordination, supramolecular and molecular chemists Presents content that is clearly structured, organized and cross-referenced to allow students, researchers and professionals to find relevant information quickly and easily
Download or read book Metallomacrocycles written by Hai-Bo Yang and published by Royal Society of Chemistry. This book was released on 2018-10-05 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of metallomacrocycles from designing complex functional metallosupramolecular systems to their applications.
