Download or read book Metabolic Inhibitors V3 written by R Hochster and published by Elsevier. This book was released on 2012-12-02 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Inhibitors: A Comprehensive Treatise, Volume III reviews developments in metabolic and enzyme inhibition. With contributions by investigators experienced in their respective fields, the book explores metabolic processes or systems and covers topics ranging from membrane transport to immunization; gene activity; DNA, RNA, and protein syntheses; photosynthesis; lipid metabolism; and blood clotting. Organized into 12 chapters, this volume begins with an overview of transport reactions and their inhibition, emphasizing inhibitors of ATPase including cations, substrates, and products. Some chapters deal with inhibitors, such as antibiotics; polypeptide and protein hormones; modified transfer RNAs; and oligonucleotides. Other chapters discuss inhibitors of immune reactions; animal virus replication; plant viruses and mycoplasma; and isozymes. An account of genetic deletions is also given. Finally, the book considers molecules that act as repressors and derepressors of gene activity. This book will be beneficial to biochemists and medical research workers, as well as to virologists, microbiologists, plant physiologists, and agronomists.
Download or read book Metabolic Inhibitors Vol III written by Hochster R M. and published by . This book was released on 1972 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Inhibitors written by Rolf Martin Hochster and published by . This book was released on 1972 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Inhibitors V1 written by R Hochster and published by Elsevier. This book was released on 2012-12-02 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Inhibitors: A Comprehensive Treatise, Volume I focuses on the properties of inhibitors of metabolic processes or enzyme systems. The book explores a wide range of substances that interfere with (and usually retard) metabolic and enzymic processes, emphasizing the inhibitor rather than the metabolic or enzymic system that is affected. Organized into 15 chapters, this volume begins with a historical overview of research on the mode of action of biological inhibitors, touching on the principle of competitive inhibition by structural analogues. The book then turns to the concept of a competitive enzymic relationship by growth inhibitory analogues and their corresponding amino acids; the metabolic inhibitory effects of polypeptides and proteins; and the use of pentoses as analogues in carbohydrate metabolism. The reader is also introduced to the metabolic inhibitory effects of fatty acids; the intermediary metabolism of phospholipids; and the inhibition of purine and pyrimidine analogues. The remaining chapters discuss the role of nucleic acids and nucleoproteins in the regulation of cellular metabolism and the inhibition of amino acid decarboxylases, cholesterol, and steroid biosynthesis. This book will be of value to biochemists, advanced students, medical research workers, and research workers in the various fields of biological chemistry, as well as those working in the microbiological, botanical, and other agricultural fields.
Download or read book Metabolic Inhibitors written by R. M. Hochster and published by . This book was released on 1970 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Inhibitors written by R. M. Hochster and published by . This book was released on 1963 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: There seems to be little doubt, when the general field of metabolic inhibition is contemplated, that the role of metabolic inhibitors in the direct control of disease is undergoing serious assessment at the present time. The manner in whitch inhibitors act, a firm knowledge of the underlying principles concerning their activities, will provide the means in the future for the development of drugs with greater potency and specieficity. The recognition of the importance of feedback mechanisms, whereby products of enzymic reactions the rates of their own synthesis, or of cases where a metabolite of one enzymic reaction sequence is also a competitive inhibitor od another, separete but related, sequence is an important step forward our understanding of cellular reaction processees. An appreciation of the properties of methabolic inhibitors drawn from a great variety of enzyme studies is vital for work which is expected to lead to further understanding of abnormal cell growth, for the development of antitumor agents, for obtaining knowledge of genetic relationships to disease conditions, and for the exploration of processes as distinct from static metabolic states. A relatively new field in the realms of biochemistry and physiology is energing from the recent work on trasport carriers across cell membrannes. Here again, a knowledge of the effects of structural analogues and other types of metabolic inhibitors on the specific processes governing the activity of such carriers is of paramount importance in the development of experimental approaches to problems of this type. This field promisses to be as crucial in future work on the control of cell behavior as knowledge of specific inhibitory phenomena of isolated enzyme systems has been in bringing us to the present stage of understanding.
Download or read book Metabolic Inhibitors V2 written by R Hochster and published by Elsevier. This book was released on 2012-12-02 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Inhibitors: A Comprehensive Treatise, Volume II charts the major advances that have been made in understanding metabolic inhibition and inhibitors. The book explores the inhibition of enzymes, such as catechol amines, acetylcholinesterases, and succinic dehydrogenases, as well as inhibitors of processes ranging from gas transport to photosynthesis, nitrogen fixation, nitrification, and oxidative phosphorylation. Organized into 23 chapters, this volume begins with a discussion on the biosynthesis of nicotinamide adenine dinucleotide and dinucleotide analogues. The reader is then introduced to the biochemical significance and mode of action of antibiotics; substances interfering with the biogenesis and metabolism of catechol amines; and inhibition of enzyme activities by thioarsenites. Some chapters focus on mercaptide-forming agents, biological alkylating agents, organophosphates, and carbamates, while others examine the metabolic inhibitory effects of quinones, fungicides, and surface active agents. The book also considers the effects of anesthetics, depressants, and tranquilizers on cerebral metabolism, and then concludes with a chapter on inhibition caused by radiation. This book is a valuable resource for biochemists, advanced students, medical research workers, and research workers in the fields of biological chemistry, microbiology, botany, and agriculture.
Download or read book Metabolic Inhibitors V4 written by R Hochster and published by Elsevier. This book was released on 2012-12-02 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Inhibitors: A Comprehensive Treatise, Volume IV reviews developments in studies of inhibition of metabolic and enzymic processes ranging from photosynthesis and blood clotting to protein synthesis, fatty acid metabolism, and phospholipid metabolism. The book also explores the inhibition of specific enzyme reactions, such as amino acid activation, amino acid hydroxylation, and cyclic AMP formation. Organized into nine chapters, this volume begins with an overview of allosteric inhibition and inhibitors, and then discusses amino acid hydroxylase inhibitors. The reader is also introduced to inhibitors and activators of enzymes that regulate the cellular concentration of cyclic AMP. In particular, the book describes the role of lipids in the activation of adenyl cyclase by hormones; modification of adenyl cyclase in various physiological and pathological conditions; and synthesis of glycerophosphatides as well as phospho- and glycosphingolipids. This book is a valuable source of information for biochemists and medical research workers as well as virologists, microbiologists, plant physiologists, and agronomists.
Download or read book Metabolic Inhibitors written by Rolf Martin Hochster and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Inhibitors written by Rolf Martin Hochster and published by . This book was released on 1965 with total page 669 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Inhibitors written by Goudot-Perrot and published by Wiley-Liss. This book was released on 1993-01-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Inhibitors written by R. M. Hochster and published by . This book was released on 1963 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Inhibitors Vol 1 written by R. M. Hochester and published by . This book was released on 1963 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic inhibitors written by R. M.. Hochster and published by . This book was released on 1963 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Inhibitors a Comprehensive Treatise V 1 4 written by R. M. K. Hochster and published by . This book was released on 1963 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Inhibitors written by Andrée Goudot-Perrot and published by . This book was released on 1992 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Method for the Detection of Metabolic Inhibitors written by Curtis Glenn Fry and published by . This book was released on 1970 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
