Download or read book Melanocortins written by Anna Catania and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is clear that the melanocortins are of immense academic interest. Further, these molecules have remarkable potential as pharmaceutical agents for treatment of multiple human and veterinary disorders and diseases. The evidence to support academic interest and clinical applications lies in significant part within the chapters of this book, chapters written by noted experts in the field who have worked diligently to understand the molecules and to move them toward clinical applications. I personally believe that the - MSH molecule and its derivatives will be used as routine therapeutics in the very near future. My belief is so strong that I left academia to form a company based on -MSH analogs and have caused millions of dollars to be spent on melanocortin research. Now why would a sane professor pick up such a challenge and enter business, an essential step toward any clinical application? It is the - MSH story that drove me. Consider that - MSH occurs in exactly the same amino acid sequence in humans and in the sea lamprey, an organism unchanged since its appearance during the Pennsylvanian period of the Paleozoic era (about 300 million years ago—way before dinosaurs were to be considered). There is unpublished evidence that the stability of the molecule can be traced back a half billion years. Frankly, I believe that the molecule existed even when single cells began to live together.

Download or read book The Melanocortin Receptors written by Roger D. Cone and published by Springer Science & Business Media. This book was released on 2000-03-14 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Roger Cone and a distinguished team of expert investigators provide the first major treatment of this critically important receptor family. The book illuminates the structure and function of these receptors through a wide-ranging review of the latest findings concerning the biology, physiology, and pharmacology of their peptide ligands and covers the major melanocortin peptides, Melanocortin-1-Receptors through Melanocortin-5-Receptors. Topics include the characterization of the melanocortin receptors, the biochemical mechanism of receptor action, and receptor function and regulation. Timely and authoritative, The Melanocortin Receptors offers an up-to-date knowledge base on the remarkably complex structure and functions of the melanocortins, a guide that will prove invaluable for today's neuroscientists, endocrinologists, pharmacologists, and other clinical and experimental investigators working in this fast moving field.

Download or read book G Protein Coupled Receptors in Energy Homeostasis and Obesity Pathogenesis written by and published by Academic Press. This book was released on 2013-01-10 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal in terms of efficacy and side effects. Reviews in this volume of Progress in Molecular Biology and Translational Science summarize current status in studies of a number of G protein-coupled receptors that were shown to be promising targets for obesity treatments. Some of these receptors also cause monogenic obesity in humans. Subject matter: obesity is an epidemic and G protein-coupled receptors are promising drug targets, with significant potential as new anti-obesity drugs Chapters are written by leading experts

Download or read book The Melanocortin System written by Roger D. Cone and published by . This book was released on 2003 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the decade before the publication of this study, melanocortin biology matured. Three additional receptors were discovered, and animal models were established addressing the function of each receptor. Researchers now know that the diverse physiologic responses to melanocortins - including their role in development, weight and endocrine regulation, cortisol production, secretion from exocrine glands, and pigmentation - can be defined in terms of individual receptors. In this text, contributors from the field of evolutionary biology, peptide chemistry, pigmentation biology, neuroscience, endocrinology and genetics provide the reader with a comprehensive review of melanocortin biology. Six areas of active research are addressed: peptide and small molecule chemistry; receptor structure and function; energy homeostasis; pigmentation; adrenocorticol function; and behaviour. There are 56 papers and 20 posters altogether, taken from the Fifth Melanocortin Meeting, held in 2002.

Download or read book Melanocortins written by Anna Catania and published by . This book was released on 2010-10-01 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Neuroendocrinology written by George Fink and published by Academic Press. This book was released on 2012 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.

Download or read book Encyclopedia of Molecular Pharmacology written by Stefan Offermanns and published by Springer Science & Business Media. This book was released on 2008-08-14 with total page 1515 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.

Download or read book Hormones Brain and Behavior written by Donald W. Pfaff and published by Academic Press. This book was released on with total page 957 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery written by Henry I. Mosberg and published by MDPI. This book was released on 2020-03-13 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery is a book dedicated to Prof. Victor J. Hruby on the occasion of his 80th birthday. This book includes twenty contributions from authors representing diverse multidisciplinary fields of scientific expertise, and is focused on the extraordinary potential of peptides and peptidomimetics as a surging therapeutic modality and as tools for basic research and technology development.

Download or read book Melanocortins Advances in Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt: Melanocortins—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Melanocortins in a concise format. The editors have built Melanocortins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Melanocortins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Melanocortins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Melanocortins Advances in Research and Application 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Melanocortins: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Melanocortins in a concise format. The editors have built Melanocortins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Melanocortins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Melanocortins: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Handbook of Biologically Active Peptides written by Abba Kastin and published by Elsevier. This book was released on 2011-04-28 with total page 1682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar. *Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity.

Download or read book Pathophysiology and Imaging Diagnosis of Demyelinating Disorders written by Evanthia Bernitsas and published by MDPI. This book was released on 2018-06-27 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Pathophysiology and Imaging Diagnosis of Demyelinating Disorders" that was published in Brain Sciences

Download or read book Chemical Factors in Neural Growth Degeneration and Repair written by C. Bell and published by Elsevier. This book was released on 1996-12-17 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an up-to-date survey of current thinking concerning the actions of chemical factors in the regulation of neuronal behaviour under normal and pathological conditions. The book is divided into four sections, dealing with chemical factors involved with the formation of axon pathways, factors involved with neuronal survival and specialization during normal development, factors involved in normal maintenance and repair of adult neurons and, finally, factors that have been implicated as mediators of degenerative changes in neurological and neuropsychiatric disorders.

Download or read book Human Sexuality and its Problems written by J. H. J. Bancroft and published by Elsevier Health Sciences. This book was released on 2008-12-29 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prepared by one of the world's leading authorities, Human Sexuality and its Problems remains the foremost comprehensive reference in the field. Now available in a larger format, this classic volume continues to address the neurophysiological, psychological and socio-cultural aspects of human sexuality and how they interact. Fully updated throughout, the new edition places a greater emphasis on theory and its role in sex research and draws on the latest global research to review the clinical management of problematic sexuality providing clear, practical guidelines for clinical intervention. Clearly written, this highly accessible volume now includes a new chapter on the role of theory, and separate chapters on sexual differentiation and gender identity development, transgender and gender non-conformity, and HIV, AIDS and other sexually transmitted diseases. Human Sexuality and its Problems fills a gap in the literature for academics interested in human sexuality from an interdisciplinary perspective, as well as health professionals involved in the management of sexual problems. Long awaited new edition of the definitive reference text on human sexuality Addresses the neurophysiological, psychological and socio-cultural aspects of human sexuality and how they interact Examines the normal sexual experience and covers the various ways in which sex can be problematic, including dysfunctional, 'out of control', high risk and illegal sexual behaviour Reviews the clinical management of problematic sexuality and provides clear, practical guidelines for clinical intervention Presents a broad cross-disciplinary perspective of the subject area making the book suitable for all professionals involved in the field Presents a more theoretical approach to the study of human sexuality reflecting recent changes in research Includes a section on brain imaging to demonstrate the latest research findings in sexual arousal and to compare and contrast individuals with normal and low levels of sexual desire Discusses the use of sex as a mood regulator and the importance of current research in this area Discusses the impact on the internet on the modern sexual world Explores the relevance of transgender and gender non-conformity Contains a chapter on HIV and AIDS and other sexually transmitted infections Chapter on therapy fully updated to reflect the movement towards integration of psychological and pharmacological approaches to management Explores the complex relationships between anger, sexual arousal and sexual violence

Download or read book The Melanotropic Peptides written by M.E. Hadley and published by CRC Press. This book was released on 2018-01-18 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three volumes on "The Melanotropic Peptides" are the outcome of a conference of the same name that was held in Tucson, Arizona, from October 11-12, 1986. The format of the three volumes provides a complete coverage of what is known about the Melanotropic Peptides. Volume I provides information on the source, synthesis, chemistry, mechanism of secretion, control of secretion, and the circulation and metabolism of the melanotropic peptides.

Download or read book Progress in Drug Research written by and published by Birkhäuser. This book was released on 2012-12-06 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: S. Ren and E.J. Lien: CaCo-2 cell permeability vs human gastrointestinal absorption: QSPR analysis.- J.C.G. Halford and J.E. Blundell: Pharmacology of appetite suppression.- B. Olivier, W. Soudijn and I. van Wijngaarden: Serotonin, dopamine and norepinephrine transporters in the central nervous system and their inhibitors.- D. Poyner, H. Cox, M. Bushfield, J.M. Treherne and M.K. Demetrikopoulos: Neuropeptides in drug research.- M. Kumari and M.K. Ticku: Regulation of NMDA receptors by ethanol.- H. Horikoshi, T. Hashimoto and T. Fujiwara: Troglitazone and emerging glitazones: new avenues for potential therapeutic benefits beyond glycemic control.- Rosamund C. Smith and Simon J. Rhodes: Applications of developmental biology to medicine and animal agriculture.