Download or read book Medicinal Fatty Acids in Inflammation written by J. Kremer and published by Springer. This book was released on 2013-03-11 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Progress in Inflammation Research is a unique compilation of work performed by a wide spectrum of investigators from different medical disciplines. It is fascinating that dietary alterations of fatty acid intake can result in a range of salutory changes in a great variety of medical conditions. Most of the good scien tific work which has led to these observations has been performed over just the last two decades. This is of course not a very long time in the context of the history of the human species. Recently performed analysis of fat intake from paleolithic times has indicated that our hunter-gatherer ancestors consumed as much cholesterol as modern Western man, but strikingly less saturated fatty acid and more polyunsatu rates, including n-3 fatty acids. Wild game has the terrestrial source of n-3 incorpo rated in its fat since browsing animals derive 18:3n-3 (alpha-linolenic acid) natural ly from leafy plants. There is, however, little opportunity for modern Western man to get n-3 fatty acids from the diet if one does not consume fish. Modern agribusiness provides ani mal feeds high in n-6 fatty acids, mostly derived from linoleic acid (18:2n-6) in corn feed. Therefore, grazing animals have no access to alternative fatty acids in either feed or grasses, the latter containing little or none of these potentially beneficial highly polyunsaturated fatty acids.
Download or read book Nutrition and Traumatic Brain Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.
Download or read book Lipids in Health and Disease written by Peter Quinn and published by Springer Science & Business Media. This book was released on 2008-08-27 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
Download or read book Omega Fatty Acids in Brain and Neurological Health written by Ronald Ross Watson and published by Academic Press. This book was released on 2019-06-12 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases. Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6 Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements
Download or read book Health Effects of Omega 3 Fatty Acids on Asthma written by and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diet immunity and inflammation written by P.C. Calder and published by Elsevier Inc. Chapters. This book was released on 2013-09-30 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: This chapter discusses the influence of dietary long-chain fatty acids on aspects of inflammation including markers of the inflammatory process and functional responses of inflammatory cells. It discusses the underlying mechanisms by which fatty acids can act and places the observations made in the context of treatment of chronic inflammatory diseases.
Download or read book Fatty Acids and Inflammatory Skin Diseases written by Jens-Michael Schröder and published by Springer Science & Business Media. This book was released on 1999 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book combines the two major functions of fatty acids in skin biol ogy. Fatty acids play an important role in the barrier function of ski n and represent a major source of proinflammatory mediators such as pr ostaglandins, leukotrienes and other lipids in inflammatory skin disor ders (e.g. proinflammatory eicosanoids which play a role in psoriasis and a topic dermatitis). The pharmacological inhibition of eicosanoid biosynthesis is also reviewed.
Download or read book The Health Benefits of Omega 3 Fatty Acids in Inflammatory Bowel Disease and Irritable Bowel Syndrome written by Maria Martin and published by Lulu.com. This book was released on 2012-06-16 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omega-3 fatty acids are known to be beneficial supplements and can benefit one's health. This book is an updated thesis that was presented to Clayton College of Natural Health in 2004 and discusses the benefits of omega-3 fatty acids in inflammatory bowel disease and irritable bowel syndrome. In addtion to explaining what these substances are and how they work in the human body, actual studies are discussed that show the benefits that these fatty acids may have in cases of IBD and IBS. Anti-inflammatory properties as well as changes in serotonin signalling with the use of omega-3's are discussed as well as the dangers of taking medications for these disorders. The omega-3 fatty acids have been shown to have many benefits in inflammatory conditions and may be useful supplements in the treatment of these digestive disorders.
Download or read book The Resolution of Inflammation written by Adriano Rossi and published by Springer Science & Business Media. This book was released on 2008-03-17 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.
Download or read book Anti inflammatory Bio activities in Fatty acid Fractions of a Lebanese Medicinal Plant written by Sabreen Faraj Fostok and published by . This book was released on 2007 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of dietary fatty acid (FA) composition in modulating inflammation has b een extensively studied. However, studies were limited to food-derived FAs, rath er than those reported to occur in certain plants, such as members of the Ranunc ulaceae family. The purpose of this study is to investigate potential anti-infla mmatory bio-activities in Ranunculus constantinopolitanus (MP), traditionally us ed in Lebanese folk medicine for the treatment of fungal infections, to compare such activities to those of fish oil and conjugated linoleic acid (CLA), via in- vitro and in-vivo models of inflammation, and to identify the bio-active molecul es underlying these activities. The endotoxin (ET)-stimulated mouse mammary epit helial SCp2 cells were utilized to assess the effect of MP on inflammation marke rs in-vitro. Wild MPI. 2 (wMPI. 2), the chloroform fraction derived from the crude methanol extract of the wild plant, in addition to wild Y2+3 (wY2+3), a FA mix isolated from this fraction and containing palmitic acid, C18:2 and C18:1, presu med to be linoleic and oleic acid, respectively, and stearic acid (1:5:8:1 ratio), reduced ET-induced interleukin (IL)-6 levels, as shown by Enzyme-Linked Immun oSorbent Assay (ELISA), without affecting cell viability or morphology. Our stud y also demonstrates that the observed effect of wY2+3 was not due to any of its individual FA constituents. Furthermore, Electrophoretic Mobility Shift Assay (E MSA) showed that the reduction in IL-6 levels was due to an upstream inhibition of ET-induced nuclear factor-KB (NF-KB) DNA-binding activity by wY2+3. However, wY2+3 did not reduce the activities of ET-induced or serum-derived gelatinase A and B, as monitored by zymography. When compared to fish oil, CLA and an analogo us synthetic FA mix, wY2+3 exhibited higher potency in reducing ET-induced IL-6 levels, both at lower effective concentrations and within a shorter period of ti me. Similar effects to those of wY2+3 were noted in cultivated Y2+3 (cY2+3), tha t showed similarities in their infrared (IR) spectra. cY2+3 did not reverse infl ammation in-vivo. A single intraperitoneal (i.p.) injection of rats with cY2+3 a t 12 mg/kg was not enough to reduce ET-induced paw edema. Taken together, our st udies demonstrate the existence of anti-inflammatory bio-activities in MP, and a ttribute them to a FA ...
Download or read book Bioactive Lipids written by A Nicolaou and published by Oily Press. This book was released on 2004-09-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Bioactive lipids, Anna Nicolaou and George Kokotos have brought together an international team of authors to discuss the nomenclature, structures, biochemistry, pharmacology and recent developments in the main classes of bioactive lipids. These lipids are essential components of the cell membrane and play many dynamic roles in mediating and controlling a wide array of cellular activities including membrane structure and organization, metabolic and gene regulation, protein structure and function, energy production, and signalling pathways. The lipid interests of scientists in the pharmaceutical and food industries are converging as the broader significance of bioactive lipids is increasingly recognized. Lipids and lipid-metabolizing enzymes are targeted for the development of new drugs. Meanwhile, functional foods, nutraceuticals and supplements already have lipids as major active ingredients. The food industry will progress from simply using lipids as ingredients, to the formulation of products that influence the synthesis, metabolism and effects of bioactive lipids in the body. These advances in applied lipid biochemistry will build on the fundamental research of lipid scientists in universities worldwide, such as those scientists contributing to Bioactive lipids.
Download or read book Military Strategies for Sustainment of Nutrition and Immune Function in the Field written by Institute of Medicine and published by National Academies Press. This book was released on 1999-05-13 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.
Download or read book Dhasco and Arasco Oils as Sources of Long chain Polyunsaturated Fatty Acids in Infant Formula written by and published by . This book was released on 2003 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lipid Mediators written by Fiona M. Cunningham and published by . This book was released on 1994 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an overview of lipid mediators from synthesis to inhibition. It addresses the immune system and its diseases from a pharmacological viewpoint and combines clinical aspects with basic science.
Download or read book Omega 3 Fatty Acids written by Mahabaleshwar V. Hegde and published by Humana Press. This book was released on 2016-09-15 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume argues for the importance of essential nutrients in our diet. Over the last two decades there has been an explosion of research on the relationship of Omega-3 fatty acids and the importance of antioxidants to human health. Expert authors discuss the importance of a diet rich in Omega-3 Fatty acids for successful human growth and development and for the prevention of disease. Chapters highlight their contribution to the prevention and amelioration of a wide range of conditions such as heart disease, diabetes, arthritis, cancer, obesity, mental health and bone health. An indispensable text designed for nutritionists, dietitians, clinicians and health related professionals, Omega-3 Fatty Acids: Keys to Nutritional Health presents a comprehensive assessment of the current knowledge about the nutritional effects of Omega-3 fatty acids and their delivery in foods.
Download or read book Lifestyle Modification for the Prevention and Treatment of Hypertension written by Paul K. Whelton and published by CRC Press. This book was released on 2003-05-16 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text compiles all available scientific evidence on the efficacy of lifestyle modification, focusing on the effective implementation of the interventional techniques and skills necessary to assist clinicians in the management of the hypertensive patient.
Download or read book Fatty Acids and Inflammatory Skin Diseases written by Jens-Michael Schroder and published by . This book was released on 2014-01-15 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: