Download or read book Mechanisms of Exacerbations and Exacerbation Frequency in Chronic Obstructive Pulmonary Disease written by Irem S. Patel and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chronic Obstructive Pulmonary Disease Exacerbations written by Jadwiga A. Wedzicha and published by CRC Press. This book was released on 2008-09-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Obstructive Pulmonary Disease Exacerbations covers the definition, diagnosis, epidemiology, mechanisms, and treatment associated with COPD exacerbations. This text also addresses imaging and how it plays a pivotal role in the diagnosis and study of exacerbations.Written by today's top experts, Chronic Obstructive Pulmonary Disease Exacerbat
Download or read book Mechanisms of Excerbations and Exacerbation Frequency in Chronic Obstructive Pulmonary Disease written by Irem S. Patel and published by . This book was released on 2009 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms and Management of COPD Exacerbations written by L. Allegra and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic obstructive pulmonary disease (COPD) is an increasingly important health problem world-wide. Whereas most other leading diseases have shown a decline in the past decades, COPD morbidity and mortality is on a steady increase. Exacerbations are usually defined as an increase in cough, a change in the colour or quantity of sputum, and a worsening dyspnea. The role of bacterial infections and the efficacy of antimicrobial therapy in acute exacerbations of chronic bronchitis (AECD) is still controversial. Exacerbations of chronic bronchitis are a common occurrence in clinical practice and are a leading cause of antibiotic prescription among respiratory infections. It is still uncertain whether each new exacerbation may deteriorate the natural history of chronic bronchitis. Undoubtedly, every episode includes a temporary worsening in lung function and may therefore pose the threat of respiratory failure or death in more severely obstructed patients.
Download or read book Models of Exacerbations in Asthma and COPD written by Ulf Sjöbring and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an overview of exacerbation models of asthma and chronic obstructive pulmonary disease (COPD). Within this wide field the book focuses on experimental systems that mimic pathobiological processes likely to be critical in exacerbations of these conditions. To generate insight into the mechanisms of exacerbation of pulmonary disease and to promote the discovery of future treatments, both animal models and human experimental models are described. For this update some of the most eminent scientists within the area of pulmonology could be recruited to share their knowledge of this evolving field of human medicine. Models of Exacerbations in Asthma and COPD will be of great interest to pulmonologists, allergologists, specialists in internal medicine and critical care, as well as to microbiologists, infectiologists and pharmacologists studying the response to respiratory infections.
Download or read book Controversies in COPD written by Antonio Anzueto and published by European Respiratory Society. This book was released on 2015-09-01 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: COPD is one of the most common diseases worldwide and is projected to be the third leading cause of death by 2020. But that does not mean it is easy to understand or manage. In everyday practice, pulmonologists face areas of controversy in COPD, for which evidence-based medicine is often unavailable. This ERS Monograph considers where the current controversies in COPD lie, discussing areas such as screening, premature birth, asthma–COPD overlap syndrome, treatment, rehabilitation and palliative care. This book will be of great interest to both clinicians and scientists, and aims to stimulate further discussion about this diverse and fascinating disease. "...contains a vast amount of information on the disease, its prevalence, signs and symptoms, diagnositc tests and treatment options. The book's format makes it quick and simple to find out what you need to know, and its size would make it easy to take to work for use in practice [...] invaluable for anyone working with patients with the disease." Emma Vincent, Nursing Standard
Download or read book Translating the Impacts of Chronic Obstructive Pulmonary Disease Exacerbations written by Laura Labonté and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Chronic obstructive pulmonary disease (COPD) is one of the most under-diagnosed chronic diseases. Its burden is mostly attributable to exacerbations, acute events of worsened symptoms that lead to disease progression as well as significant morbidity and mortality. As many individuals remain undiagnosed, exacerbations are simply treated as acute events by healthcare providers. Through lack of proper disease management, these individuals will continue to experience exacerbations, and as disease progresses, will become susceptible to many comorbid conditions. Cardiovascular (CV) comorbidity is the second cause of death among COPD patients. However, some determinants of increased CV risk could be mediated using specific interventions. An important common link between CV disease and COPD is enhanced inflammation. As such, inflammatory mediators are attractive targets for modulating CV risk in COPD. The purpose of this thesis was to evaluate the wide range of impacts of COPD exacerbations, from population burdens, to CV risk, to inflammation in subjects representing different stages of disease using a translational research approach. Two research projects were carried out to address this objective. The first consisted of an analysis of exacerbation-like respiratory events among subjects with undiagnosed and previously diagnosed COPD, embedded within an existing population based cohort study called Canadian Cohort Obstructive Lung Disease (CanCOLD). Exacerbation-like respiratory events were measured in these subjects using a questionnaire administered every three months. Differences in the characteristics of subjects with undiagnosed and diagnosed COPD were assessed, as well as those associated with reporting exacerbation-like respiratory events. The proportion of subjects reporting events and odds of using health services were also compared. The second was a local study of diagnosed COPD patients hospitalized for exacerbations, who have advanced disease and elevated CV risk. A measure of arterial stiffness, carotid-femoral pulse wave velocity (cf-PWV), and powerful predictor of CV events, was measured sequentially in these patients, as well as several inflammatory mediators and other clinical variables. The associations between these were determined over time. In the CanCOLD cohort, subjects with undiagnosed COPD had milder symptoms, better lung function and less functional impairment compared to diagnosed subjects. However, lower health-related quality of life was associated with reporting exacerbation-like respiratory events in both groups of subjects. Although the proportion of subjects reporting these events was lower among undiagnosed subjects, health service utilization was similar to that of diagnosed subjects. Within the local study, several important predictors of increased cf-PWV over time were identified, including decline in lung function and subsequent exacerbations. Additionally, club cell (CC)-16, a lung-specific inflammatory mediator was identified as a determinant of changes in cf-PWV and exacerbation frequency over time. Moreover, RelB, a nuclear factor (NF)-[kappa]B family member and mediator of pulmonary inflammation, was identified as a potential novel mediator of CV function in COPD patients.This thesis demonstrates that, at the populational level, many subjects are not diagnosed for their COPD, but experience exacerbation-like respiratory events that result in a much greater utilization of health services than previously thought. With regards to CV morbidity, several novel predictors of arterial stiffening were identified; some of these representing potentially modifiable targets. CC-16 was identified as an important novel inflammatory link between pulmonary function and CV function in COPD patients. Consequently, the results of this thesis describe the wide range of impacts of exacerbations from populational burdens to inflammation." --
Download or read book Dyspnea written by Donald A. Mahler and published by CRC Press. This book was released on 2014-01-20 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the high prevalence of chronic pulmonary diseases, including asthma, COPD, and interstitial lung disease, physicians need to recognize the cause of dyspnea and know how to treat it so that patients can cope effectively with this distressing symptom. Detailing recent developments and treatment methods, this revised and updated third edition of
Download or read book Patient Assessment in Clinical Pharmacy written by Sherif Hanafy Mahmoud and published by Springer. This book was released on 2019-03-28 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, first-of-its kind title is an indispensable resource for pharmacists looking to learn or improve crucial patient assessment skills relevant to all pharmacy practice settings. Pharmacists’ role as health care practitioners is evolving as they are taking a more active part in primary patient care -- helping patients manage their medications and diseases, providing patient education, and, in some jurisdictions, prescribing and adapting medications. To perform their day-to-day duties, pharmacists are best-served using a framework called the patient care process. This framework involves three steps: patient assessment; care plan development and implementation; and monitoring and follow up. Organized in four parts, this practical book begins with introductory chapters regarding the basics of patient assessment and the patient care process. Part II includes a detailed assessment of common symptoms encountered by pharmacists. Part III discusses assessment of patients with various chronic illnesses. Part IV addresses select specialized topics and assessment considerations. An invaluable contribution to the literature, Patient Assessment in Clinical Pharmacy: A Comprehensive Guide will be of great benefit to pharmacists, regardless of their practice setting, and to pharmacy students as well.
Download or read book Respiratory Epidemiology written by Isabella Annesi-Maesano and published by European Respiratory Society. This book was released on 2014-09-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, the volume of research into the pathophysiology and genetics of pulmonary diseases has increased greatly. This has led to the development of new treatments and therapies for many diseases, including lung cancer, asthma and cystic fibrosis. This issue of the ERS Monograph comprehensively demonstrates the developments in respiratory medicine in recent years. It outlines the importance of epidemiology in respiratory medicine, and will prove a methodological tool that will help disease management. It should also be used as an advocacy tool for the sake of public health.
Download or read book Public Health Consequences of E Cigarettes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-05-18 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.
Download or read book Chronic Obstructive Lung Diseases written by Norbert F. Voelkel and published by PMPH-USA. This book was released on 2008 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This clinical reference for practitioners offers a new and comprehensive look at chronic obstructive lung disease. Global in scale and importance, it is an important cause of morbidity and mortality. Bringing together a roster of internationally renowned contributors from the front lines of pulmonary medicine and research, it is aimed at practitioners in pulmonary medicine, pathology, thoracic radiology and epidemiology. Its focus is on the pathobiology of chronic obstructive pathology disease and emphysema and its exacerbation of chronic obstructive pulmonary disease and on treatment options. This reference works to 'connect the dots' by collating and centralizing the various data on the subject.
Download or read book Asthma and COPD written by Peter J. Barnes and published by Elsevier. This book was released on 2009-03-19 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations
Download or read book Airway Remodeling written by Peter Howarth and published by CRC Press. This book was released on 2001 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This landmark volume discusses the characteristics and impact of the remodeling process on airway function and clinical disease expression within the airway in asthma, covering pharmacological therapies and possible future targets relevant to regulating the remodeling process. Emphasizes the importance of treating underlying airway inflammation and the relevance of structural alterations to the airway wall, including glandular increases, enhanced collagen deposition within the submucosa, increased vasculature, smooth hypertrophy, and hyperplasias! Tracing the development and maintenance of bronchial hyperresponsiveness, decline in lung function, and loss of reversibility evident in chronic asthma, Airway Remodelingdescribes the contribution of inflammatory cells in the development of airway structural changes examines how pharmaceutical agents act and whether existing treatments modify or prevent remodeling in chronically inflamed asthmatic airways considers whether neural pathways initiate as well as contribute to the airway inflammatory cascade that leads to remodeling reviews the action of cytokines and growth factors on ASM signaling outlines novel approaches to regulating smooth muscle growth clarifies whether permanent ventilatory incapacity in asthma is caused by the uncoupling of the airway and the role of the lung parenchyma details high-resolution computerized tomography scan to measure the internal size of the airway at baseline, during challenge, or after bronchodilatation and more!Improving lung function and quality of life by reducing the need for emergency care, hospital admissions, and systemic steroid administration, Airway Remodeling is a superb reference for pulmonologists and respiratory system specialists; physiologists; pneumologists; allergists; pharmacologists; molecular, cellular, and lung biologists; and graduate and medical school students in these disciplines.
Download or read book Chronic Obstructive Pulmonary Disease COPD written by Onn Min Kon and published by Oxford University Press, USA. This book was released on 2008 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Obstructive Pulmonary Disease (COPD) is growing in reocnition as a major chronic disease, and a key cause of acute medical admissions. It kills approximately 30,000 patients each year in England and Wales alone, and is set to be the third commonest cause of death by 2020 globally. This pocketbook is a concise companion for all health care professionals who come into contact with patients wtih COPD. It covers the full spectrum of COPD management, ranging from smoking cessation to advanced COPD, bridging both the primary and secondary care aspects of treatment and discussing the latest advances in our understanding of the pathophysiology and new drug treatments of this disease. This compact volume of the Oxford Respiratory Medicine Library summarizes up-to-date literature in a style that will have direct clinical application to busy health care professionals.
Download or read book Global Burden of Disease and Risk Factors written by Alan D. Lopez and published by World Bank Publications. This book was released on 2006-04-02 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strategic health planning, the cornerstone of initiatives designed to achieve health improvement goals around the world, requires an understanding of the comparative burden of diseases and injuries, their corresponding risk factors and the likely effects of invervention options. The Global Burden of Disease framework, originally published in 1990, has been widely adopted as the preferred method for health accounting and has become the standard to guide the setting of health research priorities. This publication sets out an updated assessment of the situation, with an analysis of trends observed since 1990 and a chapter on the sensitivity of GBD estimates to various sources of uncertainty in methods and data.
Download or read book Lung Volume Reduction Surgery written by Michael Argenziano and published by Springer Science & Business Media. This book was released on 2002 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: A panel of recognized authorities comprehensively review the medical, surgical, and pathophysiologic issues relevant to lung volume reduction surgery for emphysema. Topics range from the open technique and video-assisted thoracoscopic approaches to LVRS, to anesthetic management, to perioperative and nursing care of the patient. The experts also detail the selection of candidates for LVRS, the clinical results and clinical trials in LVRS, and the effects of LVRS on survival rates.
