Download or read book MECHANISMS AND REGULATION OF CRANIOFACIAL MORPHOGENESIS PROCEEDINGS OF THE INTERNATIONAL CRANIOFACIAL CONFERENCE written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms and Regulation of Craniofacial Morphogenesis written by Benjamin C. Moffett and published by . This book was released on 1972 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Craniofacial Development written by and published by Academic Press. This book was released on 2015-11-27 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: Craniofacial Development, the latest volume of Current Topics in Developmental Biology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in Craniofacial Development, and includes sections on such topics as microRNAs in craniofacial development and epigenetic regulation in craniofacial development. - Provides a comprehensive book on craniofacial development and tissue regeneration - Authored by leading experts in this field - Carefully organized to cover an array of topics critical in helping readers learn the most important aspects of craniofacial development and tissue regeneration
Download or read book Cellular Mechanisms during Normal and Abnormal Craniofacial Development written by Poongodi Geetha-Loganathan and published by Frontiers Media SA. This book was released on 2022-03-30 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms and Regulation of Craniofacial Morphogenesis written by B. C. Moffett and published by . This book was released on 1973 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Giving Shape To Genomic Regulatory Networks Controlling Craniofacial And Asymmetric Organ Morphogenesis written by Ian C. Welsh and published by . This book was released on 2016 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Morphogenesis is the most critical and dynamic utilization of genomic information in the life history of an organism and a powerful system for advancing our understanding of genomic regulation and function. Stereotyped morphogenic processes provide an invaluable system for directly visualizing the functional activity of the genome via our ability to position its operational components relationally in space and time through the techniques of experimental embryology, molecular biology, and transcriptome analysis. Developmental genomics seeks to establish in vivo models to provide a cellular context where the causal relationships between the expression of key morphoregulatory genes, their transcriptional targets, and the morphogenic cellular behaviors that they control are easily determined, quantifiable, and amenable to experimental manipulation. In pursuit of this challenge, I have developed and characterized gene regulatory network models focused on two critical morphogenic processes, craniofacial development and asymmetric organ morphogenesis. Formation of the vertebrate face requires the coordinated outgrowth and fusion of multiple paired prominences. How morphogenetic domains are integrated to coordinate craniofacial development is an important question, and while a number of genes and pathways important for palate development have been identified, an understanding of how these signals are organized and integrated to achieve precise control of craniofacial development has been lacking. My analysis identifies a previously unrecognized growth zone responsible for periodic signaling center formation and the modular organization of developmentally important signaling genes and transcription factors (e.g. Shh, Bmp4, Msx1, and Barx1) in the developing palate. This newly identified growth zone provides a distributed system of common instructional cues that maintain growth of the secondary palate in proper registration with the surrounding elements of the upper jaw. Patterning of the embryonic left-right axis is essential to directing the asymmetric growth and morphology of individual organs. Overall body situs and asymmetry of organ morphology is critical to normal function and regulated by the homeobox transcription factor Pitx2. Importantly however, the gene targets and cellular behaviors controlled by Pitx2 to manifest asymmetry remain obscure. Using transcriptomics of the simple binary left-right organization of the dorsal mesentery (DM), I have elaborated and functionally characterized Pitx2 dependent asymmetric cellular processes acting on very different scales of biological organization. At the tissue level I show that regulation of asymmetric intercellular signaling is a conserved mechanism through with Pitx2 manifests differential cellular behavior to achieve asymmetric organ growth. At the chromatin level, I have leveraged the novel finding that genes physically linked to Pitx2 exhibit complementary right-specific expression relative to left-sided Pitx2 in order to characterized the relationship between 3D chromatin folding and asymmetric gene expression from the Pitx2 locus itself.
Download or read book Craniofacial Morphogenesis and Dysmorphogenesis written by Katherine W. L. Vig and published by University of Michigan Press. This book was released on 1988 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Control Mechanisms of Craniofacial Development and Growth written by and published by . This book was released on 2005 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dento Oro Craniofacial Anomalies and Genetics written by Agnes Bloch-Zupan and published by Elsevier. This book was released on 2012-03-21 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dental defects may be the physical expression of genetic defects, and so they can often be seen in a variety of syndromes associated with malformations of organs. However, dental defects are often not recognized, identified, nor characterised despite representing a possible diagnostic sign for an undiagnosed condition. This book addresses this gap by providing an understanding of dental genetics and its developmental biology counterpart. With approximately seventy well-illustrated examples, the authors present the clinical oro-facial manifestations accompanying various syndromes, providing the necessary knowledge for diagnostic purposes, as well as giving insight into recent development for each specific condition. The clarity and format of this book make it an ideal support guide both in the clinic and while conducting research. Comprehensive examination of dento/oro/craniofacial anomalies Well-illustrated examples Presented in a compact, easy to use format
Download or read book New Molecular Mechanisms Controlling Dental Epithelial Stem Cell Maintenance Growth and Craniofacial Morphogenesis written by Zhao Sun (PhD) and published by . This book was released on 2016 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interestingly, Lef-1 overexpression rescues the tooth arrest defects but not the ankyloglossia or cleft palate in Sox2 conditional deletion mice. Our data also reveal that miRNA and histone remodeler are involved in regulating DESC proliferation and craniofacial morphogenesis. We describe a miR-23a/b:Hmgn2:Pitx2 signaling pathway in regulating dental epithelial cell growth and differentiation. Pitx2 activates expression of amelogenin which is the major protein component for enamel deposition. This activation can be repressed by the chromatin-associated factor Hmgn2. miR-23a and miR-23b directly target Hmgn2, leading to the release of the Hmgn2 inhibition of Pitx2 transcriptional activity and thus enhance Amelogenin production. Phenotypically, ablation of Hmgn2 in mice results in an overgrowth of incisors with increased Amelogenin expression. The findings in this study increase our current understanding of the molecular regulation of dental epithelial stem cell fate. It not only highlights new gene regulatory network that controls dental stem cell maintenance, growth and craniofacial morphogenesis, but also sheds new light on developing novel stem cell therapy or gene therapy for tooth regeneration and dental diseases.
Download or read book Craniofacial Sutures written by David P. Rice and published by Karger Medical and Scientific Publishers. This book was released on 2008 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In this volume craniofacial developmental and evolutionary biologists, oral and maxillofacial surgeons, orthodontists as well as pediatric and plastic surgeons will find a wealth of recent information on the field of craniofacial development, deformity and its treatment."--BOOK JACKET.
Download or read book Craniofacial Growth and Development Novel Insights written by Erika Kuchler and published by Frontiers Media SA. This book was released on 2021-10-13 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Extracellular Matrix in Development written by Douglas W. DeSimone and published by Springer Science & Business Media. This book was released on 2013-03-15 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.
Download or read book MicroRNA Profiling written by Sweta Rani and published by Springer Nature. This book was released on 2022-11-28 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides updated and comprehensive methods on miRNA biogenesis and their role in the development and progression of various human diseases. Chapters detail miRNA biogenesis, isolating RNA, extracellular vesicles (EVs), circulating miRNAs, analyzing miRNA and miRDeep-P2, protocols for total RNA isolation from cells, cell-derived products, isolation and characterization of exosomes, serum, plasma specimens, and software tools. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, MicroRNA Profiling: Methods and Protocols, Second Edition aims to provide comprehensive and accessible methods to undergraduate, graduate, and established scientist.
Download or read book Morphogenesis of Skin written by Sengel and published by CUP Archive. This book was released on 1976 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vertebrate Skeletal Development written by and published by Academic Press. This book was released on 2019-03-20 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vertebrate Skeletal Development, Volume 133, the latest release in the Current Topics in Developmental Biology series, presents interesting chapters on a variety of topics, with this edition focusing on Craniofacial skeletal development, Regulatory mechanism of jawbone and tooth development, Development of the axial skeleton and intervertebral discs, Stem and progenitor cells in skeletal development, Origin, functioning and morphogenetic activity of limb synovial joint, ECM signaling in cartilage development and endochondral ossification, Sox genes in skeletal development, Wnt-Signaling in Skeletal Development, Gas signaling in skeletal development and diseases, FGF signaling in skeletal development, Bone morphogenetic growth factors in bone development, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Includes the latest information on Vertebrate Skeletal Development
Download or read book Current Therapy In Oral and Maxillofacial Surgery written by Shahrokh C. Bagheri and published by Elsevier Health Sciences. This book was released on 2011-09-19 with total page 1133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by expert surgeons and educators, Current Therapy in Oral and Maxillofacial Surgery covers the latest treatment strategies, surgical techniques, and potential complications in OMS. Emphasizing an evidence-based approach, it covers all 12 subspecialties of OMS, addressing topics from surgical principles to oral surgery, anesthesia, cranio-maxillofacial trauma surgery, head and neck surgery, maxillofacial reconstructive surgery, orthognathic surgery, pediatric craniofacial surgery including cleft lip and palate, temporomandibular joint disorders, facial plastic surgery including rhinoplasty and facelifts, obstructive sleep apnea, and oral and maxillofacial infections. At the end of each chapter, Pearls and Pitfalls summarize the authors' insight, recommendations, and experience on that topic. Editor Dr. Shahrokh Bagheri is a noted professor, researcher, and speaker on OMS, and he leads an expert author team including Dr. R. Bryan Bell and Dr. Husain Ali Khan to help you master and apply the latest advances in OMS. More than 1,200 full-color photos and 200 color line drawings illustrate concepts and provide visual guidance in clinical areas. Comprehensive sections and chapters represent essential topics, the newest advances, and controversial topics. Clinical coverage brings together the latest knowledge in OMS in a concise, easy-to-apply way. Resident-specific coverage describes the wide array of subspecialties and treatments available in the armamentarium of the modern OMS. A focus on complications ensures that you are knowledgeable in this important part of any therapy or surgical discipline. Expert contributors include the "best of the best," featuring leading, well-established, and respected surgeons and educators writing on their areas of specialty and providing current treatment strategies.
