Download or read book Mechanics in Development and Disease written by and published by Elsevier. This book was released on 2024-07-01 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanics in Development and Disease, Volume 160 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Gut developmental mechanics, Long bone developmental mechanics, Cranial plate fusion developmental mechanics, Mechanobiology and vasculogenesis, Morphogenesis and mechanics of the developing inner ear, Morphogenesis and mechanics of body wall closure in mammals, Salivary bud developmental mechanics, Lateral plate mesoderm developmental mechanics, Biomechanics of human embryo implantation, gastrulation, and organ formation, Mechanics of lung development across species, Mechanics early development in vertebrates. Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

Download or read book Mechanobiology in Health and Disease written by Stefaan Verbruggen and published by Academic Press. This book was released on 2018-08-09 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science

Download or read book Multi scale Extracellular Matrix Mechanics and Mechanobiology written by Yanhang Zhang and published by . This book was released on 2020 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.

Download or read book Mechanics of Biological Tissue written by Gerhard A. Holzapfel and published by Springer Science & Business Media. This book was released on 2006-06-03 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book points to important directions combining mechanical sciences with the new developments in biology. It delivers articles on mechanics of tissues at the molecular, cellular, tissue and organ levels.

Download or read book The Pathomechanics Of Tissue Injury And Disease And The Mechanophysiology Of Healing written by Amit Gefen and published by . This book was released on 2009-01-01 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, it became clear that mechanical factors, such as deformations, forces and stiffness properties have critical influence on a wide spectrum of diseases. Traditionally, since the 1960's, mechanics has been associated mainly with orthopaedics, trauma and rehabilitation as well as with cardiovascular problems, and so, the work of biomechanists was mostly related to these areas. This led, for example, to good understanding of the loading conditions at which bone fractures occur, and how bone fractures can be healed more quickly if their mechanical environment is adequately controlled (e.g. via compression plate-screw systems). However, more recently, on the 1980's-1990's, it was discovered that mechanics has much more fundamental roles and effects on biological processes, as many cell types appeared to be responsive to mechanical stimuli. This boosted biomechanical research on the effects of mechanical factors at the microscopic scale of tissues, and the fields of mechanobiology and mechanotransduction emerged. Most recently, on the 2000's, there were studies, e.g. by Dr. Valerie Weaver and colleagues (as described in this book), reporting that at the cell scale, inadequate mechanical stimuli may even provoke cancer. Hence, the role of integration between mechanics, life sciences and medicine is growing rapidly, and becomes more important by the day. What allows this integration to expand so fast is the development of sophisticated bioengineering research and analysis tools. These include highly realistic computer simulations, small animal MRI, micro-sensors, bio-reactors and many other recent breakthroughs that allow precision measurements of the mechanical conditions that apply in tissues at different levels of architectural hierarchy, whereas at the same time, close monitoring of the biological responses to these mechanical conditions became possible. This exciting atmosphere is at the background of the present book, which contains perspectives from leading scientists worldwide on the role of mechanics in injury, disease and healing. The topics covered span from bone tumors to pressure ulcers and from osteoarthritis to breast cancer, which illustrates how mechanics is now identified as the common denominator in so many important chronic conditions, as opposed to just trauma. In view of the multi-disciplinary and diverse nature of this book, I expect it to be appealing to a broad readership, obviously including biomechanists but also medical doctors, physiologists, cell biologists, physiotherapists, nurses and all those who are interested in reading on the latest developments in our journey towards understanding the complex connections between mechanics and biology.

Download or read book Cardiovascular Soft Tissue Mechanics written by Stephen C. Cowin and published by Springer Science & Business Media. This book was released on 2001 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cowin (New York Center for Biomedical Engineering) and Humphrey (biomedical engineering, Texas A&M U.) present seven papers that discuss current research and future directions. Topics concern tissues within the cardiovascular system (arteries, the heart, and biaxial testing of planar tissues such as heart valves). Themes include an emphasis on data on the underlying microstructure, especially collagen; the consideration of the fact that both arteries and the heart contain muscle and that there is, therefore, a need to quantify both the active and passive response; constitutive relations for active behavior; and the growth and remodeling of cardiovascular tissues. Of interest to cardiovascular and biomechanics soft tissue researchers, and bioengineers. Annotation copyrighted by Book News, Inc., Portland, OR.

Download or read book Forces in Biology Cell and Developmental Mechanobiology and Its Implications in Disease written by Selwin K. Wu and published by Frontiers Media SA. This book was released on 2020-12-11 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mechanical Engineering in Biomedical Application written by Jay Prakash Srivastava and published by John Wiley & Sons. This book was released on 2024-01-31 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: MECHANICAL ENGINEERING IN BIOMEDICAL APPLICATIONS The book explores the latest research and developments related to the interdisciplinary field of biomedical and mechanical engineering offering insights and perspectives on the research, key technologies, and mechanical engineering techniques used in biomedical applications. The book is divided into several sections that cover different aspects of mechanical engineering in biomedical research. The first section focuses on the role of additive manufacturing technologies, rehabilitation in healthcare applications, and artificial recreation of human organs. The section also covers the advances, risks, and challenges of bio 3D printing. The second section presents insight into biomaterials, including their properties, applications, and fabrication techniques. The section also covers the use of powder metallurgy methodology and techniques of biopolymer and bio-ceramic coatings on prosthetic implants. The third section covers biofluid mechanics, including the mechanics of fluid flow within our body, the mechanical aspects of human synovial fluids, and the design of medical devices for fluid flow applications. The section also covers the use of computational modeling to study the blockage of carotid arteries. The final section elaborates on soft robotic manipulation for use in medical sciences. Audience The book provides practical insights and applications for mechanical engineers, biomedical engineers, medical professionals, and researchers working on the design and development of biomedical devices and implants.

Download or read book Multi scale Extracellular Matrix Mechanics and Mechanobiology written by Yanhang Zhang and published by Springer. This book was released on 2019-07-12 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.

Download or read book Musculoskeletal Disorders and the Workplace written by Institute of Medicine and published by National Academies Press. This book was released on 2001-05-24 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every year workers' low-back, hand, and arm problems lead to time away from jobs and reduce the nation's economic productivity. The connection of these problems to workplace activities-from carrying boxes to lifting patients to pounding computer keyboards-is the subject of major disagreements among workers, employers, advocacy groups, and researchers. Musculoskeletal Disorders and the Workplace examines the scientific basis for connecting musculoskeletal disorders with the workplace, considering people, job tasks, and work environments. A multidisciplinary panel draws conclusions about the likelihood of causal links and the effectiveness of various intervention strategies. The panel also offers recommendations for what actions can be considered on the basis of current information and for closing information gaps. This book presents the latest information on the prevalence, incidence, and costs of musculoskeletal disorders and identifies factors that influence injury reporting. It reviews the broad scope of evidence: epidemiological studies of physical and psychosocial variables, basic biology, biomechanics, and physical and behavioral responses to stress. Given the magnitude of the problem-approximately 1 million people miss some work each year-and the current trends in workplace practices, this volume will be a must for advocates for workplace health, policy makers, employers, employees, medical professionals, engineers, lawyers, and labor officials.

Download or read book Integrative Mechanobiology written by Yu Sun and published by Cambridge University Press. This book was released on 2015-11-12 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of its kind, this comprehensive resource integrates cellular mechanobiology with micro-nano techniques to provide unrivalled in-depth coverage of the field, including state-of-the-art methods, recent advances, and biological discoveries. Structured in two parts, the first part offers detailed analysis of innovative micro-nano techniques including FRET imaging, electron cryo-microscopy, micropost arrays, nanotopography devices, laser ablation, and computational image analysis. The second part of the book provides valuable insights into the most recent technological advances and discoveries in areas such as stem cell, heart, bone, brain, tumor, and fibroblast mechanobiology. Written by a team of leading experts and well-recognised researchers, this is an essential resource for students and researchers in biomedical engineering.

Download or read book Biofluid Mechanics written by David Rubenstein and published by Academic Press. This book was released on 2015-07-28 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation shows how fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement, renal transport among other specialty circulations. This new second edition increases the breadth and depth of the original by expanding chapters to cover additional biofluid mechanics principles, disease criteria, and medical management of disease, with supporting discussions of the relevance and importance of current research. Calculations related both to the disease and the material covered in the chapter are also now provided. Uses language and math that is appropriate and conducive for undergraduate learning, containing many worked examples and end-of-chapter problems Develops all engineering concepts and equations within a biological context Covers topics in the traditional biofluids curriculum, and addresses other systems in the body that can be described by biofluid mechanics principles Discusses clinical applications throughout the book, providing practical applications for the concepts discussed NEW: Additional worked examples with a stronger connection to relevant disease conditions and experimental techniques NEW: Improved pedagogy, with more end-of-chapter problems, images, tables, and headings, to better facilitate learning and comprehension of the material

Download or read book Handbook of Imaging in Biological Mechanics written by Corey P. Neu and published by CRC Press. This book was released on 2014-10-24 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging imaging techniques have opened new fronts to investigate tissues, cells, and proteins. Transformative technologies such as microCT scans, super-resolution microscopy, fluorescence-based tools, and other methods now allow us to study the mechanics of cancer, dissect the origins of cellular force regulation, and examine biological specimens

Download or read book Understanding Lung Acinar Micromechanics in Health and Disease Linking Quantitative Imaging and Organ Scale Mechanics by Computational Modeling written by Matthias Ochs and published by Frontiers Media SA. This book was released on 2021-02-26 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Branching Morphogenesis written by Jamie Davies and published by Springer Science & Business Media. This book was released on 2007-03-20 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Branching morphogenesis, the creation of branched structures in the body, is a key feature of animal and plant development. This book brings together, for the first time, expert researchers working on a variety of branching systems to present a state-of-the-art view of the mechanisms that control branching morphogenesis. Systems considered range from single cells, to blood vessel and drainage duct systems to entire body plans, and approaches range from observation through experiment to detailed biophysical modelling. The result is an integrated overview of branching.

Download or read book Inborn Errors of Development written by Charles J. Epstein and published by Oxford University Press, USA. This book was released on 2004 with total page 1110 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the clinical chapters are organized into sections by defined developmental pathways or gene families, and each section is preceded by a general overview. For each disorder the authors cover the disease-causing genes, the role of these genes in development as elucidated in model organisms, the human mutations that have been identified, and the developmental pathogenesis of the condition. Clinical descriptions, along with discussions of therapy and counseling, are provided. This book will be an invaluable resource for physicians, dentists, and other health professionals and for basic scientists interested in developmental processes and genetic perturbations that affect them.

Download or read book Physical Biology of the Cell written by Rob Phillips and published by Garland Science. This book was released on 2012-10-29 with total page 1089 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that