Download or read book Matrix assisted Laser Desorption ionization Mass Spectral Studies on Transition Metal and Main Group Atom Clusters written by Nancy Carter Dopke and published by . This book was released on 1998 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fundamental Studies of Matrix assisted Laser Desorption Ionization Mass Spectrometry written by Lisa Michelle Preston-Schaffter and published by . This book was released on 1994 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Laser Desorption Ionization Mass Spectrometry Based on Nanophotonic Structure From Material Design to Mechanistic Understanding written by Moon-Ju Kim and published by Springer Nature. This book was released on 2023-11-11 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents innovative laser desorption ionization (LDI)-active nanophotonic structures for addressing the challenges that matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) is currently facing and for enhancing LDI efficiency. It presents a variety of cutting-edge nanophotonic structures to satisfy the mass-analytical needs of sensitivity, reproducibility, and quantification. As opposed to the commercialized, conventional organic matrix used in MALDI-MS, these nanostructures are validated to be highly effective in detecting small metabolites and drugs, highlighting their considerable potential in the mass spectrometry field. It also systematically elucidates fundamental LDI processes in terms of the photo-thermal, electronic, and structural characteristics of nanophotonic structures, offering mechanistic knowledge of LDI-MS. Even though LDI-MS performance is heavily influenced by a number of nanostructure parameters, relatively little is known about the LDI processes associated with those characteristics. An in-depth understanding of nanostructure characteristics and LDI mechanisms thus paves the way for more effective, rational design and development of nanostructures with improved LDI capabilities. Further, with a focus on multiple cascades in nanostructure functions in response to laser pulse stimuli, this book provides detailed, step-by-step procedures to design and construct a nanophotonic, LDI-active platform, which may serve as a roadmap for graduate students in the field of mass spectrometry. Readers, including graduate students, researchers, and experts working in the related areas of mass spectrometry, nanophotonics, and material science and material engineering, will find a wealth of useful information in this book.

Download or read book Fundamental Studies of Matrix assisted Laser Desorption ionization Time of flight Mass Spectrometry MALDI TOF MS and Its Applications to the Analysis of Biological Materials written by Yongdong Zhu and published by . This book was released on 1999 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Matrix Assisted Laser Desorption Ionization Quadrupole Time of flight Mass Spectrometry of Poly 2 vinylpyridine written by Donna M. Smith and published by . This book was released on 2005 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Matrix assisted Laser Desorption ionization Mass Spectrometry written by Pao-Chi Liao and published by . This book was released on 1995 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Trinuclear Rhenium III Halide Clusters with Carboxylate Ligands written by Jeffrey S. Dougan and published by . This book was released on 2003 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in MALDI and Laser Induced Soft Ionization Mass Spectrometry written by Rainer Cramer and published by Springer. This book was released on 2016-08-23 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI (electrospray ionization) • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics

Download or read book Matrix assisted Laser Desorption ionization Mass Spectrometric Study of Biologic Molecules written by Yan-Hui Liu and published by . This book was released on 1996 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Matrix Isolation Spectroscopy written by A. Barnes and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: The matrix isolation (MI) method has now been used for nearly thirty years. During this period it has been actively developed and the range of problems tackled greatly extended. Originally it was used for studies of transient species involv ing vibrational, electronic and ESR spectroscopy. Nowadays the study of transient species forms a comparatively small part of HI work since it has been amply demonstrated that very fruitful information can be obtained of the structure and interactions of stable molecules and their aggregates. In addition to the s~ectroscopic methods mentioned above the MI technique is nowadays a standard method in research based on vibrational relaxation, luminescence, Mossbauer, magnetic circular dichroism, pulsed NMR and photoelectron spectroscopy. The matrix isolation technique affords considerable advantages over more conventional methods in most applications of spectroscopy. Areas where the technique has been widely applied, or shows great potential, include: metal atom chemistry, and its relation to surface chemistry, high temperature inorganic species, transition metal complexes, interstellar species, free radicals and unstable molecules, conformational studies, molecular com plexes, and intermolecular forces.

Download or read book Exploration of the Quantitative Aspects of Matrix assisted Laser Desorption Ionization Time of flight Mass Spectrometry written by Runbo Li and published by . This book was released on 2013 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advisor: Kevin G. Owens, Ph.D.

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2003 with total page 860 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Quantification by Matrix Assisted Laser Desorption Ionization Mass Spectrometry Using An Approach Based On Stochastic Dynamics Experimental And Theoretical Correspondences written by Bojidarka Ivanova and published by GRIN Verlag. This book was released on 2018-05-14 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Paper (postgraduate) from the year 2018 in the subject Chemistry - Analytical Chemistry, grade: Mass spectrometry, University of Dortmund (Institut für Umweltforschung, Lehrstuhl für Analytische Chemie), language: English, abstract: The goal of this work is to describe more recent developments in the quantitative mass spectrometry and to illustrate how our new model equations based on the stochastic dynamics relate to the determining the 3D molecular and electronic structures of analytes. It is aimed at researchers in Chemistry who would like to find out about what is going on in mass spectrometric methodological contributions more recently. The work could also be used to MSc and PhD students in the field of Chemistry, in particular, highlighting the ‘Analytical chemistry’, ‘Physico–chemistry’ and/or ‘Computational and theoretical chemistry’, respectively.

Download or read book Electrospray assisted Laser Desorption Ionization Mass Spectrometry for Proteomic Studies written by Ivory Xingyu Peng and published by . This book was released on 2009 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Matrix assisted Laser Desorption ionization and Ion Activation by Fourier transform Mass Spectroscopy written by John Anthony Castoro and published by . This book was released on 1993 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mass Spectrometry Bulletin written by and published by . This book was released on 1999 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies on Surface Assisted Laser Desorption Ionization and Its Analytical Application in Imaging Mass Spectrometry written by Ho-Wai Tang and published by . This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Studies on surface-assisted laser desorption/ionization and its analytical application in imaging mass spectrometry" by Ho-wai, Tang, 鄧浩維, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Surface-Assisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) is an analytical technique enabling direct chemical analysis of solid samples. Analytes could be desorbed/ionized upon nitrogen laser irradiation from a SALDI substrate-coated sample, then analyzed by MS. The substrate is involved in the transfer of laser energy to the analytes, and eventually assists the desorption/ionization of analytes. The analytical performance of SALDI-MS, such as detection sensitivity, is dependent on different parameters of the substrate, such as size, morphology and form. In this thesis, the effects of several substrate parameters on the SALDI process were investigated. SALDI-MS based Imaging Mass Spectrometry (IMS) method was also developed using efficient SALDI substrate identified in the fundamental studies. IMS is a chemical-specific mapping technique which allows parallel mapping of multiple analytes in solid samples. The desorption mechanism of SALDI is investigated using two groups of substrate, the carbon allotropes and the noble metal nanoparticles. Ion desorption efficiency and internal energy transfer were probed and correlated in carbon-based SALDI. It was found that the ion desorption efficiency and internal energy transfer was in opposite order. Substrate that transferred more internal energy to ions did not show higher ion desorption efficiency. This result could not be explained by the Thermal Desorption model which was a generally believed mechanism of the SALDI desorption process. A non-thermal model, the Phase Transition model is proposed to account for the SALDI desorption process. The Phase Transition model suggests that the substrate is melted/ restructured upon laser irradiation, and this will assist ion desorption. The Phase Transition model is supported by the morphological change of carbon substrates after SALDI and high initial velocity of ions desorbed by carbon-based SALDI (> 1,000 ms-1). SALDI-MS is useful for small molecule analysis due to the relatively clean background in the low mass region. SALDI-IMS is developed and applied to the imaging of spatial distribution of small molecules in forensic and biological samples. Gold nanoparticles (AuNPs) was selected as the substrate from several other noble metal NPs. A solvent-free method, argon ion sputtering, was employed for coating AuNPs on sample surface prior to SALDI-IMS analysis. Fine details of the samples, such as the fine pattern of latent fingerprints and handwriting on questioned documents can be preserved and imaged reliably by avoiding the use of solvent. Fatty acids, drugs and ink components can be imaged in forensic samples including latent fingerprints, banknotes and checks. The solvent-free SALDI-IMS method was also applied to image the distribution of metabolites in intact animal tissues. Spatial distributions of neurotransmitters, nucleobases and fatty acids can be imaged from mouse brain and tumor tissue sections. DOI: 10.5353/th_b4714555 Subjects: Mass spectrometry Imaging systems