Download or read book Mathilda Savitch written by Victor Lodato and published by Macmillan. This book was released on 2009-09-15 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathilda investigates her older sister's shattering death and learns perplexing truths when she accesses her sister's computer journals and reads about a secret underworld life.

Download or read book Ion Channels and Disease written by Frances M. Ashcroft and published by Academic Press. This book was released on 1999-10-20 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies. Ion Channels and Disease provides an informative and up-to-date account of our present understanding of ion channels and the molecular basis of ion channel diseases. It includes a basic introduction to the relevant aspects of molecular biology and biophysics and a brief description of the principal methods used to study channelopathies. For each channel, the relationship between its molecular structure and its functional properties is discussed and ways in which genetic mutations produce the disease phenotype are considered. This book is intended for research workers and clinicians, as well as graduates and advanced undergraduates. The text is clear and lively and assumes little knowledge, yet it takes the reader to frontiers of what is currently known about this most exciting and medically important area of physiology. - Introduces the relevant aspects of molecular biology and biophysics - Describes the principal methods used to study channelopathies - Considers single classes of ion channels with summaries of the physiological role, subunit composition, molecular structure and chromosomal location, plus the relationship between channel structure and function - Looks at those diseases associated with defective channel structures and regulation, including mutations affecting channel function and to what extent this change in channel function can account for the clinical phenotype

Download or read book Mathilda Savitch written by Victor Lodato and published by Anchor Canada. This book was released on 2010-08-03 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fiercely funny and touching debut novel of a young girl uncovering the truth about her sister’s death. Fear doesn’t come naturally to Mathilda Savitch. She prefers to look directly at things nobody else can even mention: for example, her beloved older sister’s death. She was pushed in front of a train by a man who is still on the loose, and after a year of searching for clues, Mathilda has come no closer to the truth about Helene’s murder…until she cracks her email password and a whole secret life emerges — one that swiftly draws Mathilda into her sister’s world of clouded motives and strange emotions. If she can find the keys to Helene’s past, she’s sure she can wake her family from their nightmare of grief. But in crossing into that underworld and tracing her sister’s footsteps, she has to risk everything that matters to her. Mathilda Savitch is a poignant, furiously funny, and tender page-turner from an extraordinary debut novelist.

Download or read book Edgar and Lucy written by Victor Lodato and published by Macmillan. This book was released on 2017-03-07 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eight-year-old Edgar Fini's loyalty is torn between the two women in his life. There's his mother, Lucy, who, though she has moments where she loves him, mostly disappears at night with her various 'suitors'. And then there's his grandmother, Florence, who dotes on him to the point where she is at a loss when he isn't around. Since his father's suicide, Florence and Edgar's relationship has become obsessive, each fully dependent on the other. When Florence suddenly dies, Lucy is thrown into the role of main caretaker and doesn't know how to handle her new job. But as Edgar and Lucy adjust, they must also deal with Ron, a local butcher who wants to court Lucy, and Conrad, an unsettlingly attentive adult whose intentions are at one more sinister and more innocent than Edgar could ever know.

Download or read book The Ice Age written by Kirsten Reed and published by Text Publishing. This book was released on 2009-06-29 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: We stopped at a roadside diner. People asked if I was his daughter. They ask all the time. Hoping, accusing. We never say yes, and we never say no. We ate our food at a booth in a hungry, self-conscious rush, straight out of the wrappers. They didn't have plates. We left a tip, just change. The waitress scooped it up straight away as we slid out of the booth. She was middle-aged and bulgy, in a proper matronly waitress's dress. She shot us what I suppose was intended to be a look of gratitude. She really only managed a weak glare. I guess that's the countryside for you. People are a little edgy.' Across the heartless expanse of middle America, a teenaged girl is riding shotgun with an older man. She watches him; she sees her fascination tallied in the black looks of waitresses, the knowing smiles of motel clerks. The man can see no proper way of conducting this relationship but is bound to her by concern and tenderness; perhaps desire. The girl craves only closeness. She knows the Ice Age is coming, and we will need to huddle together for warmth. Kirsten Reed's debut novel, with its echoes of Nabokov, Kerouac and Bret Easton Ellis, captures the translucent moment at the end of childhood in all its awkwardness, sincerity and heedless vulnerability. In prose both lyrical and earthy, comic and darkly harrowing, this extraordinary young writer creates a journey of irresistible momentum and tragic possibility. It will leave you with the sense that you have met someone significant; and you will not soon forget her.

Download or read book She s Come Undone written by Wally Lamb and published by Simon and Schuster. This book was released on 2012-12-11 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meet Dolores Price. She's thirteen, wise-mouthed but wounded. Beached like a whale in front of her bedroom TV, she spends the next few years nourishing herself with the chocolate, crisps and Pepsi her anxious mother supplies. When she finally rolls into young womanhood at 257 pounds, Dolores is no stronger and life is no kinder. But this time she's determined to rise to the occasion and give herself one more chance before really going belly up. In his extraordinary coming-of-age odyssey, Wally Lamb invites us to hitch an incredible ride on a journey of love, pain, and renewal with the most heartbreakingly comical heroine to come along in years. At once a fragile girl and a hard-edged cynic, so tough to love yet so inimitably loveable, Dolores is as poignantly real as our own imperfections.

Download or read book The Eyes of Darkness written by Dean Koontz and published by Penguin. This book was released on 2011-04-05 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: A mother’s greatest wish—or worst nightmare—comes true in this chilling novel by #1 New York Times bestselling author Dean Koontz. Tina Evans has spent a year suffering from incredible heartache since her son Danny's tragic death. But now, with her Vegas show about to premiere, Tina can think of no better time for a fresh start. Maybe she can finally move on and put her grief behind her. Only there is a message for Tina, scrawled on the chalkboard in Danny's room: NOT DEAD. Two words that send her on a terrifying journey from the bright lights of Las Vegas to the cold shadows of the High Sierras, where she uncovers a terrible secret...

Download or read book The Last Policeman written by Ben H. Winters and published by Quirk Books. This book was released on 2012-07-10 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: "[The] weird, beautiful, unapologetically apocalyptic Last Policeman trilogy is one of my favorite mystery series."—John Green, author of The Fault in Our Stars and Paper Towns Winner of the 2013 Edgar® Award Winner for Best Paperback Original! What’s the point in solving murders if we’re all going to die soon, anyway? Detective Hank Palace has faced this question ever since asteroid 2011GV1 hovered into view. There’s no chance left. No hope. Just six precious months until impact. The Last Policeman presents a fascinating portrait of a pre-apocalyptic United States. The economy spirals downward while crops rot in the fields. Churches and synagogues are packed. People all over the world are walking off the job—but not Hank Palace. He’s investigating a death by hanging in a city that sees a dozen suicides every week—except this one feels suspicious, and Palace is the only cop who cares. The first in a trilogy, The Last Policeman offers a mystery set on the brink of an apocalypse. As Palace’s investigation plays out under the shadow of 2011GV1, we’re confronted by hard questions way beyond “whodunit.” What basis does civilization rest upon? What is life worth? What would any of us do, what would we really do, if our days were numbered? Ebook contains an excerpt from the anticipated second book in the trilogy, Countdown City.

Download or read book The Long March written by Shuyun Sun and published by Doubleday Books. This book was released on 2006 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recounts the events of China's Long March, describing the odyssey of thousands of Chinese Communists from their bases to the remote north of China and discussing stories behind the March, including ruthless purges, hunger and disease, and mistreatment ofwomen.

Download or read book The Best American Short Stories 2015 written by T. Coraghessan Boyle and published by Houghton Mifflin Harcourt. This book was released on 2015-10-06 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents twenty of the best works of short fiction of the past year from a variety of acclaimed sources.

Download or read book Mobilizing Minerva written by Kimberly Jensen and published by University of Illinois Press. This book was released on 2008 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: American women did more than pursue roles as soldiers, doctors, and nurses during World War I. Mobilizing Minerva: American Women in the First World War reveals women's motivations for fighting for full citizenship rights both on and off the battlefield. The war provided chances for women to participate in the military, but also in other male-dominated career paths. Intense discussions of rape, methods of protecting women, and proper gender roles abound as Kimberly Jensen draws from rich case studies to show how female thinkers and activists wove wartime choices into long-standing debates about woman suffrage and economic parity. The war created new urgency in these debates, and Jensen forcefully presents the case of women participants and activists: women's involvement in the obligation of citizens to defend the state validated their right of full female citizenship.

Download or read book Miss O Dell written by Chris O'Dell and published by Simon and Schuster. This book was released on 2009-10-06 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ultimate fly-on-the wall memoir packed with revelations, intimate insights, and history-making moments from the tour manager, friend, lover, and confidante to some of the most revered rock icons of the 60's, 70's and 80's. Chris O’Dell wasn’t famous. She wasn’t even almost famous. But she was there. From witnessing music history in the recording studio with The Beatles to working for The Rolling Stones during their infamous 1972 American tour, Chris O'Dell has seen and worked for the most influential musicians in rock history during some of their most intimate and awe-inspiring moments. She was in the studio when the Beatles recorded The White Album, Abbey Road, and Let It Be, and she sang in the Hey Jude chorus. She lived with George Harrison and Pattie Boyd and unwittingly got involved in Pattie’s famous love story with Eric Clapton. She’s the subject of Leon Russell’s Pisces Apple Lady. She’s “the woman down the hall” in Joni Mitchell’s song Coyote, the “mystery woman” pictured on the Stones album Exile on Main Street, and the Miss O’Dell of George Harrison’s song. The remarkable, intimate story of an ordinary woman who lived the dream of millions—to be part of rock royalty’s inner circle—Miss O’Dell is a backstage pass to some of the most momentous events in rock history.

Download or read book The Last Camel Died at Noon written by Elizabeth Peters and published by Grand Central Publishing. This book was released on 2010-03-01 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bestselling author Peters brings back 19th-century Egyptologist Amelia Peabody and her entourage in a delicious caper that digs up mystery in the shadow of the pyramids.

Download or read book Pumpgirl written by Abbie Spallen and published by . This book was released on 2006 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: There's one in every town, and they call her the Pumpgirl. She works in the garage, changes the oil and thinks she's one of the lads. She's sweet on 'No-helmet' Hammy, but he loves no-one but himself. He's out all night with his racing boys, whilst wife Sinead's off on a joyride of her own, with an ache that's about to be cured. A turbo charged race through the diesel fumes and country music of the Armagh badlands. Abbie Spallen's explosively comic new play takes us deep into the unspoken thoughts and darkest desires of three lives destined to collide. The Bush Theatre's world premiere production of Pumpgirl opened at the Traverse Theatre, in the 2006 Edinburgh Fringe Festival.

Download or read book Kumiko and the Dragon written by Briony Stewart and published by Univ. of Queensland Press. This book was released on 2015-08-01 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kumiko doesn't like going to bed. She can't sleep, and the reason she can't sleep is because of the giant dragon that sits outside her bedroom window, every single night. So one night she plucks up the courage to ask the dragon to leave, not knowing that the truth she is about to discover is more thrilling than anything she could ever have imagined. This delightful story will take the young readers on a soaring dragon adventure, as Kumiko discovers a strength she never even knew she had.

Download or read book Motherhouse written by Victor Lodato and published by Samuel French, Inc.. This book was released on 2010 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Clive arrives unexpectedly at the house of his mother and his sister. He says that he is fleeing from the police, but perhaps it's another one of his delusions. Unbeknownst to him, he has shown up on a tragic anniversary. Three years prior, his sister's child was killed in a brutal shooting. As fate seems bent on shattering the walls, mother Mae valiantly attempts to keep house"--Publisher description.

Download or read book Arlington written by book and lyrics by Victor Lodato and published by Dramatists Play Service, Inc.. This book was released on 2016-05-16 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE STORY: It's a sunny day and Sara Jane is trying valiantly to keep it that way. Her young husband, Jerry, is away at war, and though Sara Jane believes in the cause, nothing has seemed quite right lately—especially the last few messages from Jerry. At least she has her piano—and Jerry’s bourbon—to keep her company as she tries to figure things out. But how far will she go to keep the impending storm at bay? ARLINGTON is a stirring, funny and powerful new work from playwright/novelist Victor Lodato and award-winning composer Polly Pen.