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Book Mathematical Structures in Population Genetics

Download or read book Mathematical Structures in Population Genetics written by I︠U︡riĭ Ilʹich Li︠u︡bich and published by Springer. This book was released on 1992-03-16 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Very Good,No Highlights or Markup,all pages are intact.

Book Mathematical Structures in Population Genetics

Download or read book Mathematical Structures in Population Genetics written by Yuri I. Lyubich and published by Springer. This book was released on 1992 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical methods have been applied successfully to population genet ics for a long time. Even the quite elementary ideas used initially proved amazingly effective. For example, the famous Hardy-Weinberg Law (1908) is basic to many calculations in population genetics. The mathematics in the classical works of Fisher, Haldane and Wright was also not very complicated but was of great help for the theoretical understanding of evolutionary pro cesses. More recently, the methods of mathematical genetics have become more sophisticated. In use are probability theory, stochastic processes, non linear differential and difference equations and nonassociative algebras. First contacts with topology have been established. Now in addition to the tra ditional movement of mathematics for genetics, inspiration is flowing in the opposite direction, yielding mathematics from genetics. The present mono grapll reflects to some degree both patterns but especially the latter one. A pioneer of this synthesis was S. N. Bernstein. He raised-and partially solved- -the problem of characterizing all stationary evolutionary operators, and this work was continued by the author in a series of papers (1971-1979). This problem has not been completely solved, but it appears that only cer tain operators devoid of any biological significance remain to be addressed. The results of these studies appear in chapters 4 and 5. The necessary alge braic preliminaries are described in chapter 3 after some elementary models in chapter 2.

Book Information Geometry and Population Genetics

Download or read book Information Geometry and Population Genetics written by Julian Hofrichter and published by Springer. This book was released on 2017-02-23 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner. In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner. Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.

Book Some Mathematical Models from Population Genetics

Download or read book Some Mathematical Models from Population Genetics written by Alison Etheridge and published by Springer Science & Business Media. This book was released on 2011-01-07 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work reflects sixteen hours of lectures delivered by the author at the 2009 St Flour summer school in probability. It provides a rapid introduction to a range of mathematical models that have their origins in theoretical population genetics. The models fall into two classes: forwards in time models for the evolution of frequencies of different genetic types in a population; and backwards in time (coalescent) models that trace out the genealogical relationships between individuals in a sample from the population. Some, like the classical Wright-Fisher model, date right back to the origins of the subject. Others, like the multiple merger coalescents or the spatial Lambda-Fleming-Viot process are much more recent. All share a rich mathematical structure. Biological terms are explained, the models are carefully motivated and tools for their study are presented systematically.

Book Foundations of Mathematical Genetics

Download or read book Foundations of Mathematical Genetics written by Anthony William Fairbank Edwards and published by Cambridge University Press. This book was released on 2000-01-13 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: A definitive account of the origins of modern mathematical population genetics, first published in 2000.

Book Mathematical Topics in Population Genetics

Download or read book Mathematical Topics in Population Genetics written by Ken-ichi Kojima and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: A basic method of analyzing particulate gene systems is the proba bilistic and statistical analyses. Mendel himself could not escape from an application of elementary probability analysis although he might have been unaware of this fact. Even Galtonian geneticists in the late 1800's and the early 1900's pursued problems of heredity by means of mathe matics and mathematical statistics. They failed to find the principles of heredity, but succeeded to establish an interdisciplinary area between mathematics and biology, which we call now Biometrics, Biometry, or Applied Statistics. A monumental work in the field of popUlation genetics was published by the late R. A. Fisher, who analyzed "the correlation among relatives" based on Mendelian gene theory (1918). This theoretical analysis over came "so-called blending inheritance" theory, and the orientation of Galtonian explanations for correlations among relatives for quantitative traits rapidly changed. We must not forget the experimental works of Johanson (1909) and Nilsson-Ehle (1909) which supported Mendelian gene theory. However, a large scale experiment for a test of segregation and linkage of Mendelian genes affecting quantitative traits was, prob ably for the first time, conducted by K. Mather and his associates and Panse in the 1940's.

Book Mathematical Population Genetics 1

Download or read book Mathematical Population Genetics 1 written by Warren J. Ewens and published by Springer Science & Business Media. This book was released on 2012-10-01 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.

Book Genetic Structure and Selection in Subdivided Populations  MPB 40

Download or read book Genetic Structure and Selection in Subdivided Populations MPB 40 written by François Rousset and published by Princeton University Press. This book was released on 2013-02-15 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Various approaches have been developed to evaluate the consequences of spatial structure on evolution in subdivided populations. This book is both a review and new synthesis of several of these approaches, based on the theory of spatial genetic structure. François Rousset examines Sewall Wright's methods of analysis based on F-statistics, effective size, and diffusion approximation; coalescent arguments; William Hamilton's inclusive fitness theory; and approaches rooted in game theory and adaptive dynamics. Setting these in a framework that reveals their common features, he demonstrates how efficient tools developed within one approach can be applied to the others. Rousset not only revisits classical models but also presents new analyses of more recent topics, such as effective size in metapopulations. The book, most of which does not require fluency in advanced mathematics, includes a self-contained exposition of less easily accessible results. It is intended for advanced graduate students and researchers in evolutionary ecology and population genetics, and will also interest applied mathematicians working in probability theory as well as statisticians.

Book The Geometry of Population Genetics

Download or read book The Geometry of Population Genetics written by Ethan Akin and published by Springer Science & Business Media. This book was released on 2013-04-09 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: The differential equations which model the action of selection and recombination are nonlinear equations which are impossible to It is even difficult to describe in general the solve explicitly. Recently, Shahshahani began using qualitative behavior of solutions. differential geometry to study these equations [28]. with this mono graph I hope to show that his ideas illuminate many aspects of pop ulation genetics. Among these are his proof and clarification of Fisher's Fundamental Theorem of Natural Selection and Kimura's Maximum Principle and also the effect of recombination on entropy. We also discover the relationship between two classic measures of 2 genetic distance: the x measure and the arc-cosine measure. There are two large applications. The first is a precise definition of the biological concept of degree of epistasis which applies to general (i.e. frequency dependent) forms of selection. The second is the unexpected appearance of cycling. We show that cycles can occur in the two-locus-two-allele model of selection plus recombination even when the fitness numbers are constant (i.e. no frequency dependence). This work is addressed to two different kinds of readers which accounts for its mode of organization. For the biologist, Chapter I contains a description of the entire work with brief indications of a proof for the harder results. I imagine a reader with some familiarity with linear algebra and systems of differential equations. Ideal background is Hirsch and Smale's text [15].

Book Mathematical Theories of Populations

Download or read book Mathematical Theories of Populations written by Frank. Hoppensteadt and published by SIAM. This book was released on 1975-01-01 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical theories of populations have appeared both implicitly and explicitly in many important studies of populations, human populations as well as populations of animals, cells and viruses. They provide a systematic way for studying a population's underlying structure. A basic model in population age structure is studied and then applied, extended and modified, to several population phenomena such as stable age distributions, self-limiting effects, and two-sex populations. Population genetics are studied with special attention to derivation and analysis of a model for a one-locus, two-allele trait in a large randomly mating population. The dynamics of contagious phenomena in a population are studied in the context of epidemic diseases.

Book From Genetics to Mathematics

Download or read book From Genetics to Mathematics written by Miroslaw Lachowicz and published by World Scientific. This book was released on 2009 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains pedagogical and elementary introductions to genetics for mathematicians and physicists as well as to mathematical models and techniques of population dynamics. It also offers a physicist''s perspective on modeling biological processes. Each chapter starts with an overview followed by the recent results obtained by authors. Lectures are self-contained and are devoted to various phenomena such as the evolution of the genetic code and genomes, age-structured populations, demography, sympatric speciation, the Penna model, Lotka-Volterra and other predator-prey models, evolutionary models of ecosystems, extinctions of species, and the origin and development of language. Authors analyze their models from the computational and mathematical points of view.

Book Population Genetics and Microevolutionary Theory

Download or read book Population Genetics and Microevolutionary Theory written by Alan R. Templeton and published by John Wiley & Sons. This book was released on 2006-09-29 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

Book Mathematical Population Genetics

Download or read book Mathematical Population Genetics written by Warren J. Ewens and published by . This book was released on 1979 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Mathematical Population Genetics And Evolution Of Bacterial Cooperation

Download or read book Mathematical Population Genetics And Evolution Of Bacterial Cooperation written by Volker Hosel and published by World Scientific. This book was released on 2020-03-13 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Social life of bacteria is in the focus of recent research. Bacteria are simple enough to be accessible by science, but still complex enough to show cooperation, division of labor, bet-hedging, cross-talk and synchronized activities, and a rich variety of social traits. A central question of evolutionary theory is the explanation why this social life did develop, and why these systems are evolutionary stable. This book introduces the reader into the theory of evolution, covering classical models and as well as recent developments. The theory developed is used to represent the up-to-date understanding of social bacteria.This book will be useful for students and lecturers interested in mathematical evolutionary theory, as well as for researchers as a reference.

Book Introduction to Theoretical Population Genetics

Download or read book Introduction to Theoretical Population Genetics written by Thomas Nagylaki and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers those areas of theoretical population genetics that can be investigated rigorously by elementary mathematical methods. I have tried to formulate the various models fairly generally and to state the biological as sumptions quite explicitly. I hope the choice and treatment of topics will en able the reader to understand and evaluate detailed analyses of many specific models and applications in the literature. Models in population genetics are highly idealized, often even over idealized, and their connection with observation is frequently remote. Further more, it is not practicable to measure the parameters and variables in these models with high accuracy. These regrettable circumstances amply justify the use of appropriate, lucid, and rigorous approximations in the analysis of our models, and such approximations are often illuminating even when exact solu tions are available. However, our empirical and theoretical limitations justify neither opaque, incomplete formulations nor unconvincing, inadequate analy ses, for these may produce uninterpretable, misleading, or erroneous results. Intuition is a principal source of ideas for the construction and investigation of models, but it can replace neither clear formulation nor careful analysis. Fisher (1930; 1958, pp. x, 23-24, 38) not only espoused similar ideas, but he recognized also that our concepts of intuition and rigor must evolve in time. The book is neither a review of the literature nor a compendium of results. The material is almost entirely self-contained. The first eight chapters are a thoroughly revised and greatly extended version of my published lecture notes (Nagylaki, 1977a).

Book Theoretical Aspects of Population Genetics

Download or read book Theoretical Aspects of Population Genetics written by Motoo Kimura and published by Princeton University Press. This book was released on 1971-10-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: To show the importance of stochastic processes in the change of gene frequencies, the authors discuss topics ranging from molecular evolution to two-locus problems in terms of diffusion models. Throughout their discussion, they come to grips with one of the most challenging problems in population genetics--the ways in which genetic variability is maintained in Mendelian populations. R.A. Fisher, J.B.S. Haldane, and Sewall Wright, in pioneering works, confirmed the usefulness of mathematical theory in population genetics. The synthesis their work achieved is recognized today as mathematical genetics, that branch of genetics whose aim is to investigate the laws governing the genetic structure of natural populations and, consequently, to clarify the mechanisms of evolution. For the benefit of population geneticists without advanced mathematical training, Professors Kimura and Ohta use verbal description rather than mathematical symbolism wherever practicable. A mathematical appendix is included.