Download or read book Genomic and Precision Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2022-04-09 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. - Provides a comprehensive volume written and edited by oncology genomic specialists for oncology health providers - Includes succinct commentary and key learning points that will assist providers with their local needs for implementation of genomic and personalized medicine into practice - Presents an up-to-date overview on major opportunities for genomic and personalized medicine in practice - Covers case studies that highlight the practical use of genomics in the management of patients

Download or read book Algebra in the Stone Cech Compactification written by Neil Hindman and published by Walter de Gruyter. This book was released on 2011-12-23 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second revised and extended edition of the successful book on the algebraic structure of the Stone-Čech compactification of a discrete semigroup and its combinatorial applications, primarily in the field known as Ramsey Theory. There has been very active research in the subject dealt with by the book in the 12 years which is now included in this edition. This book is a self-contained exposition of the theory of compact right semigroups for discrete semigroups and the algebraic properties of these objects. The methods applied in the book constitute a mosaic of infinite combinatorics, algebra, and topology. The reader will find numerous combinatorial applications of the theory, including the central sets theorem, partition regularity of matrices, multidimensional Ramsey theory, and many more.

Download or read book Algebraic Homotopy written by Hans J. Baues and published by Cambridge University Press. This book was released on 1989-02-16 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a general outlook on homotopy theory; fundamental concepts, such as homotopy groups and spectral sequences, are developed from a few axioms and are thus available in a broad variety of contexts. Many examples and applications in topology and algebra are discussed, including an introduction to rational homotopy theory in terms of both differential Lie algebras and De Rham algebras. The author describes powerful tools for homotopy classification problems, particularly for the classification of homotopy types and for the computation of the group homotopy equivalences. Applications and examples of such computations are given, including when the fundamental group is non-trivial. Moreover, the deep connection between the homotopy classification problems and the cohomology theory of small categories is demonstrated. The prerequisites of the book are few: elementary topology and algebra. Consequently, this account will be valuable for non-specialists and experts alike. It is an important supplement to the standard presentations of algebraic topology, homotopy theory, category theory and homological algebra.

Download or read book Recent Advances in Geometric Inequalities written by Dragoslav S. Mitrinovic and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cryptology and Error Correction written by Lindsay N. Childs and published by Springer. This book was released on 2019-04-18 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents a careful introduction to methods of cryptology and error correction in wide use throughout the world and the concepts of abstract algebra and number theory that are essential for understanding these methods. The objective is to provide a thorough understanding of RSA, Diffie–Hellman, and Blum–Goldwasser cryptosystems and Hamming and Reed–Solomon error correction: how they are constructed, how they are made to work efficiently, and also how they can be attacked. To reach that level of understanding requires and motivates many ideas found in a first course in abstract algebra—rings, fields, finite abelian groups, basic theory of numbers, computational number theory, homomorphisms, ideals, and cosets. Those who complete this book will have gained a solid mathematical foundation for more specialized applied courses on cryptology or error correction, and should also be well prepared, both in concepts and in motivation, to pursue more advanced study in algebra and number theory. This text is suitable for classroom or online use or for independent study. Aimed at students in mathematics, computer science, and engineering, the prerequisite includes one or two years of a standard calculus sequence. Ideally the reader will also take a concurrent course in linear algebra or elementary matrix theory. A solutions manual for the 400 exercises in the book is available to instructors who adopt the text for their course.

Download or read book Genetics and Biotechnology written by Ulrich Kück and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycology, the study of fungi, originated as a subdiscipline of botany and was a descriptive discipline, largely neglected as an experimental science until the early years of this century. A seminal paper by Blakeslee in 1904 provided evidence for self incompatibility, termed "heterothallism", and stimulated interest in studies related to the control of sexual reproduction in fungi by mating-type specificities. Soon to follow was the demonstration that sexually reproducing fungi exhibit Mendelian inheritance and that it was possible to conduct formal genetic analysis with fungi. The names Burgeff, Kniep and Lindegren are all associated with this early period of fungal genetics research. These studies and the discovery of penicillin by Fleming, who shared a Nobel Prize in 1945, provided further impetus for experimental research with fungi. Thus began a period of interest in mutation induction and analysis of mutants for bio chemical traits. Such fundamental research, conducted largely with Neurospora crassa, led to the one gene: one enzyme hypothesis and to a second Nobel Prize for fungal research awarded to Beadle and Tatum in 1958. Fundamental research in biochemical genetics was extended to other fungi, especially to Saccharomyces cere visiae, and by the mid-1960s fungal systems were much favored for studies in eukaryotic molecular biology and were soon able to compete with bacterial systems in the molecular arena.

Download or read book Electromagnetics and Calculation of Fields written by Nathan Ida and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: This introduction to electromagnetic fields emphasizes the computation of fields and the development of theoretical relations. It presents the electromagnetic field and Maxwell's equations with a view toward connecting the disparate applications to the underlying relations, along with computational methods of solving the equations.

Download or read book Knowledge Based Simulation written by Paul A. Fishwick and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge-Based Simulation: Methodology and Application represents a recent compilation of research material that reviews fundamental concepts of simulation methodology and knowledge-based simulation applications. Knowledge-based simulation represents a new and exciting bridge area linking the fields of computer simulation and artificial intelligence. This book will appeal to both theorists and practitioners who require simulation to solve complex problems. A primary attraction of the book is its emphasis on both methodology and applications. In this way, the reader can explore new methods for encoding knowledge-inten- sive information into a simulation model, and new applications that utilize these methods.

Download or read book HIV Vaccines and Cure written by Linqi Zhang and published by Springer. This book was released on 2018-07-20 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.

Download or read book Advanced Information Systems Engineering written by Anne Persson and published by Springer. This book was released on 2004-08-18 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: th CAiSE 2004 was the 16 in the series of International Conferences on Advanced Information Systems Engineering. In the year 2004 the conference was hosted by the Faculty of Computer Science and Information Technology, Riga Technical University, Latvia. Since the late 1980s, the CAiSE conferences have provided a forum for the presentation and exchange of research results and practical experiences within the ?eld of Information Systems Engineering. The conference theme of CAiSE 2004 was Knowledge and Model Driven Information Systems Engineering for Networked Organizations. Modern businesses and IT systems are facing an ever more complex en- ronment characterized by openness, variety, and change. Organizations are - coming less self-su?cient and increasingly dependent on business partners and other actors. These trends call for openness of business as well as IT systems, i.e. the ability to connect and interoperate with other systems. Furthermore, organizations are experiencing ever more variety in their business, in all c- ceivable dimensions. The di?erent competencies required by the workforce are multiplying. In the same way, the variety in technology is overwhelming with a multitude of languages, platforms, devices, standards, and products. Moreover, organizations need to manage an environment that is constantly changing and where lead times, product life cycles, and partner relationships are shortening. ThedemandofhavingtoconstantlyadaptITtochangingtechnologiesandbu- ness practices has resulted in the birth of new ideas which may have a profound impact on the information systems engineering practices in future years, such as autonomic computing, component and services marketplaces and dynamically generated software.

Download or read book Biosensors for Direct Monitoring of Environmental Pollutants in Field written by D.P. Nikolelis and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors offer clear and distinct advantages over standard analytical methods for the direct monitoring of environmental pollutants in the field, such as real-time detection with minimum sample preparation and handling. The present book highlights recent advantages that will be of great value to a range of scientists, researchers and students dealing with analytical and environmental chemistry and biosensor technology. It presents recent trends in analytical methodology for the determination of indoor and outdoor pollutants, advances in DNA, biological and recognition-based sensors, examples of biosensors for use in field and water analysis, biosensors based on non-aqueous systems, and recent advances in the miniaturisation and micromachining of biosensors.

Download or read book Transmission of Information by Orthogonal Functions written by Henning F. Harmuth and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: The orthogonality of functions has been exploited in communications since its very beginning. Conscious and 1 extensive use was made of it by KOTEL NIKOV in theoretical work in 1947. Ten years later a considerable number of people were working in this field rather independently. However, little experimental use could be made of the theo retical results before the arrival of solid state opera tional amplifiers and integrated circuits. A theory of communication based on orthogonal functions could ·have been published many years ago. However, the only useful examples of orthogonal functions at that time were sine .... cosine functions and block pulses, and this made the theory appear to be a complicated way to derive known re sults. It was again the advance of semiconductor techno logy that produced the first really new, useful example of orthogonal functions: the little-known Walsh functions. In this book emphasis is placed on the Walsh functions, since ample literature is available on sine-cosine func tions as well as on block pulses and pulses derived from them.

Download or read book Dynamics Theory and Applications written by Thomas R. Kane and published by McGraw-Hill College. This book was released on 1985-01-01 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Wavelets Made Easy written by Yves Nievergelt and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the nature and computation of mathematical wavelets, which provide a framework and methods for the analysis and the synthesis of signals, images, and other arrays of data. The material presented here addresses the au dience of engineers, financiers, scientists, and students looking for explanations of wavelets at the undergraduate level. It requires only a working knowledge or memories of a first course in linear algebra and calculus. The first part of the book answers the following two questions: What are wavelets? Wavelets extend Fourier analysis. How are wavelets computed? Fast transforms compute them. To show the practical significance of wavelets, the book also provides transitions into several applications: analysis (detection of crashes, edges, or other events), compression (reduction of storage), smoothing (attenuation of noise), and syn thesis (reconstruction after compression or other modification). Such applications include one-dimensional signals (sounds or other time-series), two-dimensional arrays (pictures or maps), and three-dimensional data (spatial diffusion). The ap plications demonstrated here do not constitute recipes for real implementations, but aim only at clarifying and strengthening the understanding of the mathematics of wavelets.

Download or read book Perception of Displayed Information written by Lucien Biberman and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: As this book took form, its contents furnished the material for a graduate course at the University of Rhode Island. Toward the end of that course, the class reviewed the literature on display characteristics and design. The universal criticism voiced in those reviews was that there was lots of hardware information but no criteria upon which one could base a sound design. Though one could learn all about the size and brightness of various displays, one could not form any judgment about how ef fectively the display transferred information to an observer. As I reviewed our nearly completed text, an announcement crossed my desk stating that one of the professional societies in a seminar was to consider if one should not attempt to formulate a theory concerning information transfer from displays to an observer. That was the first title chosen for our book, before our publisher told us that "that was a paragraph, not a title. " The group of contributors to this book have labored long in the conviction that there was a real need to develop and present a consolidated theory based upon the work of a number of pioneers, including Barnes and Czerny, de Vries, Rose, Coltman and Anderson, Schade, Johnson, van Meeteren, and others, who established the various parts of a substantial theoretical and experimental back ground that seemed ripe for consolidation.

Download or read book Physics in Biology and Medicine written by Paul Davidovits and published by Academic Press. This book was released on 2008 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition covers topics in physics as they apply to the life sciences, specifically medicine, physiology, nursing and other applied health fields. It includes many figures, examples and illustrative problems and appendices which provide convenient access to the most important concepts of mechanics, electricity, and optics.

Download or read book Grasping in Robotics written by Giuseppe Carbone and published by Springer Science & Business Media. This book was released on 2012-11-15 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Grasping in Robotics contains original contributions in the field of grasping in robotics with a broad multidisciplinary approach. This gives the possibility of addressing all the major issues related to robotized grasping, including milestones in grasping through the centuries, mechanical design issues, control issues, modelling achievements and issues, formulations and software for simulation purposes, sensors and vision integration, applications in industrial field and non-conventional applications (including service robotics and agriculture). The contributors to this book are experts in their own diverse and wide ranging fields. This multidisciplinary approach can help make Grasping in Robotics of interest to a very wide audience. In particular, it can be a useful reference book for researchers, students and users in the wide field of grasping in robotics from many different disciplines including mechanical design, hardware design, control design, user interfaces, modelling, simulation, sensors and humanoid robotics. It could even be adopted as a reference textbook in specific PhD courses.