Download or read book Master Control Genes in Development and Evolution written by Walter J. Gehring and published by Yale University Press. This book was released on 1998-01-01 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fascinating book, one of the world's most eminent developmental biologists discusses some of the exciting new insights into how genes control development. Walter Gehring describes in vivid detail his essential contributions to the landmark discovery of the homeobox, a characteristic DNA segment found in the genes of all higher organisms from the fruitfly to humans, and he explains how this has provided the key to our modern understanding of development and evolution. The book thus becomes not only a lucid discussion of genetics but also an engaging description of the art of scientific investigation. Gehring begins his story by looking at the work of the many researchers who laid the foundation for the fields of molecular, cellular, and developmental biology, providing insightful vignettes of past and present investigators. He then describes his laboratory's hunt for the gene that caused odd mutations in the fruitfly--in which, for example, antennae on the head were transformed into legs. He explains that researchers eventually found that the same master control genes that dictate the body plan in flies also pattern human bodies, limbs, hands, heart, and brain. And he illustrates the universality of the genetic control of development by describing the development of the eye; eyes as different as those of humans, squids, and flies, he shows, develop under the same master control gene.
Download or read book The Regulatory Genome written by Eric H. Davidson and published by Elsevier. This book was released on 2010-07-19 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. - The only book in the market that is solely devoted to the genomic regulatory code for animal development - Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding - Presents a comprehensive treatment of molecular control elements that determine the function of genes - Provides a comparative treatment of development, based on principles rather than description of developmental processes - Considers the evolutionary processes in terms of the structural properties of gene regulatory networks - Includes 42 full-color descriptive figures and diagrams
Download or read book Drosophila Eye Development written by Kevin Moses and published by Springer Science & Business Media. This book was released on 2002-03-12 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1 Kevin Moses It is now 25 years since the study of the development of the compound eye in Drosophila really began with a classic paper (Ready et al. 1976). In 1864, August Weismann published a monograph on the development of Diptera and included some beautiful drawings of the developing imaginal discs (Weismann 1864). One of these is the first description of the third instar eye disc in which Weismann drew a vertical line separating a posterior domain that included a regular pattern of clustered cells from an anterior domain without such a pattern. Weismann suggested that these clusters were the precursors of the adult ommatidia and that the line marks the anterior edge of the eye. In his first suggestion he was absolutely correct - in his second he was wrong. The vertical line shown was not the anterior edge of the eye, but the anterior edge of a moving wave of patterning and cell type specification that 112 years later (1976) Ready, Hansen and Benzer would name the "morphogenetic furrow". While it is too late to hear from August Weismann, it is a particular pleasure to be able to include a chapter in this Volume from the first author of that 1976 paper: Don Ready! These past 25 years have seen an astonishing explosion in the study of the fly eye (see Fig.
Download or read book The Concept of the Gene in Development and Evolution written by Peter J. Beurton and published by Cambridge University Press. This book was released on 2000-05-29 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biological research in the latter half of the twentieth century have made the story of the gene vastly complicated: the more we learn about genes, the less sure we are of what a gene really is. Knowledge about the structure and functioning of genes abounds, but the gene has also become curiously intangible. This collection of essays renews the question: what are genes? Philosophers, historians and working scientists re-evaluate the question in this volume, treating the gene as a focal point of interdisciplinary and international research. It will be of interest to professionals and students in the philosophy and history of science, genetics and molecular biology.
Download or read book Chance and Necessity written by Jacques Monod and published by . This book was released on 1997 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Change and necessity is a statement of Darwinian natural selection as a process driven by chance necessity, devoid of purpose or intent.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Morpho functional Machines The New Species written by F. Hara and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Morpho-functional Machines are a set of tools for investigating the design of embodied intelligence in autonomous bio-artifact systems. The focus in Morpho-functional Machines is on the balance of morphology, materials, and control; intelligent behavior emerges from the interaction of an autonomous system with a real-world environment. How, then, should body morphology, body materials, and sensory systems be designed to achieve a certain set of tasks or desired behaviors in a particular environment? This and other questions were addressed at the International Workshop on Morpho-functional Machines held in Tokyo in 2001. Collected here are the revised papers from the workshop, providing a new perspective for understanding embodied intelligence. Presenting the innovative concept of Morpho-functional Machines, this book is a valuable source for scientists and engineers working in ethnology, cognitive sciences, robotic engineering, and artificial intelligence.
Download or read book HOX Genes written by and published by Academic Press. This book was released on 2009-07-19 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: A subgroup of homeobox genes, which play an important role in the developmental processes of a variety of multicellular organisms, Hox genes have been shown to play a critical role in vertebrate pattern formation. Hox genes can be thought of as general purpose control genes—that is, they are similar in many organisms and direct the same processes in a variety of organisms, from mouse, to fly, to human. - Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area - Inclusion of chapters that discuss the evolutionary development of a wide variety of organisms - Gives researchers and clinicians insight into how defective Hox genes trigger developmental abnormalities in embryos
Download or read book The Epistemology of Development Evolution and Genetics written by Richard Burian and published by Cambridge University Press. This book was released on 2005 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: These essays examine the developments in three fundamental biological disciplines--embryology, evolutionary biology, and genetics. These disciplines were in conflict for much of the 20th century and the essays in this collection examine key methodological problems within these disciplines and the difficulties faced in overcoming the conflicts between them. Burian skillfully weaves together historical appreciation of the settings within which scientists work, substantial knowledge of the biological problems at stake and the methodological and philosophical issues faced in integrating biological knowledge drawn from disparate sources.
Download or read book Developmental Genetics written by Gurbachan S. Miglani and published by I. K. International Pvt Ltd. This book was released on 2013-12-30 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development is behind what one looks like. It is directed by genes, the units of heredity, which are made up to deoxyribonucleic acid (DNA) in all animals (including man), plants, microorganisms and most of the viruses except in some viruses where ribonucleic acid (RNA) is the genetic material. Developmental Genetics integrates the two disciplines of development and genetics into one. Key Features: Each chapter begins with a brief introduction and historical background. The text explains both classical and recent material. Various phenomena of developmental genetics explained with examples of animals, plant, bacteria and viruses. Text explained with suitable examples, illustrations, tables and figures. List of references and review questions given at the end of each chapter Exhaustive glossary, author index and subject index given at the end of the book. This book is essential reading for postgraduate in developmental genetics, teachers teaching this subject and developmental biologists conducting research in this area. It is also suitable for candidates preparing for ARS/UGC NET examination.
Download or read book Modularity in Development and Evolution written by Gerhard Schlosser and published by University of Chicago Press. This book was released on 2004-07 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modularity in Development and Evolution offers the first sustained exploration of modules from developmental and evolutionary perspectives. Contributors discuss what modularity is, how it can be identified and modeled, how it originated and evolved, and its biological significance. Covering modules at levels ranging from genes to colonies, the book focuses on their roles not just in structures but also in processes such as gene regulation. Among many exciting findings, the contributors demonstrate how modules can highlight key constraints on evolutionary processes. A timely synthesis of a crucial topic, Modularity in Development and Evolution shows the invaluable insights modules can give into both developmental complexities and their evolutionary origins.
Download or read book Genetics written by Daniel L. Hartl and published by Jones & Bartlett Publishers. This book was released on 2012 with total page 830 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetics written by Daniel Hartl and published by Jones & Bartlett Publishers. This book was released on 2012 with total page 831 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook gives an introduction to genetics and genomics at the college level. It contains a chapter on human genetic evolution. Other chapters treat transmission genetics, molecular genetics and evolutionary genetics and provide an understanding of the basic process of gene transmission, mutation, expression and regulation.
Download or read book The Structure of Evolutionary Theory written by Stephen Jay Gould and published by Harvard University Press. This book was released on 2002-03-21 with total page 1099 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world's most revered and eloquent interpreter of evolutionary ideas offers here a work of explanatory force unprecedented in our time--a landmark publication, both for its historical sweep and for its scientific vision. With characteristic attention to detail, Stephen Jay Gould first describes the content and discusses the history and origins of the three core commitments of classical Darwinism: that natural selection works on organisms, not genes or species; that it is almost exclusively the mechanism of adaptive evolutionary change; and that these changes are incremental, not drastic. Next, he examines the three critiques that currently challenge this classic Darwinian edifice: that selection operates on multiple levels, from the gene to the group; that evolution proceeds by a variety of mechanisms, not just natural selection; and that causes operating at broader scales, including catastrophes, have figured prominently in the course of evolution. Then, in a stunning tour de force that will likely stimulate discussion and debate for decades, Gould proposes his own system for integrating these classical commitments and contemporary critiques into a new structure of evolutionary thought. In 2001 the Library of Congress named Stephen Jay Gould one of America's eighty-three Living Legends--people who embody the "quintessentially American ideal of individual creativity, conviction, dedication, and exuberance." Each of these qualities finds full expression in this peerless work, the likes of which the scientific world has not seen--and may not see again--for well over a century.
Download or read book Gene Regulation and Metabolism written by Julio Collado-Vides and published by MIT Press. This book was released on 2002 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of current computational approaches to metabolism and gene regulation.
Download or read book Genes Development and Cancer written by Howard D. Lipshitz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: - For the first time, Nobel Prize winner, Edward B. Lewis' research papers are published within one volume - Papers are organized into sections that reflect the focus of the research - Commentaries by Howard Lipshitz highlight key methods and results by explaining the science so it is accessible to upper-level undergraduates, graduate students, and professional researchers
Download or read book Towards a Theory of Development written by Alessandro Minelli and published by Oxford University Press. This book was released on 2014 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the foundations of ontogeny by asking how the development of living things should be understood. It explores key concepts of developmental biology, asks whether general principles of development can be discovered, and what the role of models and theories is in developmental biology.
