Download or read book Natural Products Analysis written by Vladimir Havlicek and published by John Wiley & Sons. This book was released on 2014-10-13 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights analytical chemistry instrumentation and practices applied to the analysis of natural products and their complex mixtures, describing techniques for isolating and characterizing natural products. • Applies analytical techniques to natural products research – an area of critical importance to drug discovery • Offers a one-stop shop for most analytical methods: x-ray diffraction, NMR analysis, mass spectrometry, and chemical genetics • Includes coverage of natural products basics and highlights antibacterial research, particularly important as efforts to combat drug resistance gain prominence • Covers instrumental techniques with enough detail for both current practitioners and beginning researchers

Download or read book Mass Spectrometry of Natural Products written by B. Sklarz and published by Franklin Book Company. This book was released on 1978 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mass Spectrometry of Natural Substances in Food written by Fred Mellon and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introducing the principles, practice and applications of mass spectrometric techniques in the study of natural substances in foods, this book conveys the depth and breadth of modern mass spectrometry in relation to food analysis. It covers traditional techniques such as electron and chemical ionisation and newer soft ionisation techniques such as matrix-assisted laser desorption ionisation and electrospray. All of these techniques are especially relevant in food quality and safety studies and in biopolymer analysis. The ability to analyse biopolymers by mass spectrometry is having a major impact on the study of food structure components, food proteins, food pathogens and food components produced from genetically modified organisms. The principles and practice of mass spectrometry are covered in the early chapters and are followed by applications in flavour analysis and the determination of non-nutrient, biologically-active, natural substances in foods. The analysis and metabolic studies of amino acids, peptides, proteins, lipids, sugars, carbohydrates and vitamins is also discussed, with separate chapters on mineral and micronutrient metabolism and techniques of pyrolysis mass spectrometry. Mass Spectrometry of Natural Substances in Food will be a valuable resource for food scientists, food analysts and others working in food research, nutrition and safety.

Download or read book Methodologies for Metabolomics written by Norbert W. Lutz and published by Cambridge University Press. This book was released on 2013-01-21 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.

Download or read book Modern Phytochemical Methods written by Nikolaus H. Fischer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains reviews which are based on a symposium, given th at the 30 meeting of The Phytochemical Society of North America, held at Laval University in Quebec City, Canada on August 11-15, 1990. During the past two decades, there have been major new developments in methods which can be applied toward the isolation, separation and structure determination of complex natural products. Therefore, the topic of this symposium, "Modem Phytochemical Methods", is a very timely one. The organizers of the symposium recognized that it would not be possible to cover in detail all new advances in phytochemical methodology. It was therefore decided to emphasize general reviews on recent developments of major separation techniques such as high performance liquid chromatography as well as supercritical fluid chromato graphy. In addition, advances in commonly used structure determination methods, mainly NMR and MS, are reviewed. Other topics include methodo logies of micro-sampling for isolation and analysis of trichome constituents as well as recent breakthroughs on biosynthetic studies of monoterpenes using "enriched" basal cells of trichomes. The volume concludes with a review of quantitative structure-activity relationship (QSAR) studies of biologically active natural products. In Chapter I, K. Hostettmann and his colleagues give a general review of recent developments in the separation of natural products with major emphasis on preparative separations of biologically active plant constituents. The authors present a comparison of droplet countercurrent chromatography (OCCC) with the highly rapid and more versatile centrifugal partition chromatography (CPC).

Download or read book Mass Spectrometry Based Metabolomics in Clinical and Herbal Medicines written by Aihua Zhang and published by John Wiley & Sons. This book was released on 2021-08-20 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlights the importance and benefit of mass spectrometry-based metabolomics for identifying biomarkers that accurately screen for potential biomarkers of diseases Mass spectrometry-based metabolomics offer new opportunities for biomarker discovery in complex diseases and may provide pathological understanding of diseases beyond traditional technologies. It is the systematic analysis of low-molecular-weight metabolites in biological samples and has been applied to discovering and identifying the perturbed pathways. Currently, mass spectrometry-based metabolomics has become an important tool in clinical research and the diagnosis of human disease. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines comprehensively presents the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics such as metabolites analysis, biomarker discovery, technical challenges, discovery of natural product, mechanism interpretation of action, discovery of active ingredients, clinical application and precision medicine, and enhancing their biomedical value in a real world of biomedicine, shedding light on the potential for spectrometry-based metabolomics. It highlights the value of mass spectrometry-based metabolomics and metabolism to address the complexity of herbal medicines in systems pharmacology, especially, to link phytochemical analysis with the assessment of pharmacological effect and therapeutic potential. Each chapter has been laid out with introduction, method, up-to-date literature, identification of biomarker, and applications Covers the current state, challenges, and applications of high-throughput mass spectrometry-based metabolomics in the discovery of biomarker, active ingredients, natural product, etc. Constitutes a unique and indispensable practical guide for any phytochemistry or related laboratory, and provides hands-on description of new techniques Provides a guide for new practitioners of pharmacologists, pharmacological scholars, drug developers, botanist, researchers of traditional medicines. Mass Spectrometry-Based Metabolomics in Clinical and Herbal Medicines provides a landmark of mass spectrometry-based metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all biomedical science fields.

Download or read book Bioactive Natural Products written by Steven M. Colegate and published by CRC Press. This book was released on 2007-12-14 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive natural products are proving to be a rich source of novel therapeutics to both protect against and combat diseases, as well as serve as lead compounds in crop protection. Following the successful format of the first edition, this volume brings together collective research from many new contributors and emphasizes the rationale behind the

Download or read book Mass Spectrometry of Natural Products written by B. Sklarz and published by Elsevier. This book was released on 2013-09-11 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry of Natural Products covers the plenary lectures presented at the International Mass Spectrometry Symposium on Natural Products, held in Rehovot, Israel from August 28 to September 2, 1977. The book focuses on the sequencing, spectroscopy, chromatography, and spectrometry of natural products. The selection first discusses mass spectrometric sequencing of peptides and proteins and mass spectroscopic investigation of nucleic acid degradation products. The book then examines advances in the mass spectrometry of steroids, including sterols with unsaturated side chains and ring D fragmentation of saturated sterols and steranes. The text evaluates the mass spectrometry and language of biological fluids. Topics include separation by glass capillary chromatography and structure of determination of unknown compounds. The book also focuses on structural and sequencing studies on peptides, proteins, and glycopeptide by mass spectrometry and directed fragmentation in mass spectrometry by the introduction of functional groups. The selection is a dependable reference for readers interested in mass spectrometry of natural products.

Download or read book Recent Advances in Natural Products Analysis written by Seyed Mohammad Nabavi and published by Elsevier. This book was released on 2020-03-07 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Natural Products Analysis is a thorough guide to the latest analytical methods used for identifying and studying bioactive phytochemicals and other natural products. Chemical compounds, such as flavonoids, alkaloids, carotenoids and saponins are examined, highlighting the many techniques for studying their properties. Each chapter is devoted to a compound category, beginning with the underlying chemical properties of the main components followed by techniques of extraction, purification and fractionation, and then techniques of identification and quantification. Biological activities, possible interactions, levels found in plants, the effects of processing, and current and potential industrial applications are also included. Focuses on the latest analytical techniques used for studying phytochemical and other biological compounds Authored and edited by the top worldwide experts in their field Discusses the current and potential applications and predicts future trends of each compound group

Download or read book Chemistry of Natural Products written by K. Anand Solomon and published by MJP Publisher. This book was released on 2019-06-11 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products, i.e., products from Nature, be it of plant or animal origin, plays a major role in human life. Hence their isolation and characterization of natural products will help in understanding their mode of action with reference to their biological and pharmacological activity. The book has been written with a view that it would help both students and researchers who are in their initial stages of exploration in the field of Natural product chemistry.The importance of natural products, techniques for the analysis,interpretation of the data and finally its role in health care has been dealt with. With the voluminous information available on each such topic, only the basic aspect, hopefully to elicit interest in further exploration has been discussed.

Download or read book Mass Spectrometry in Chemical Biology written by Norberto Peporine Lopes and published by Royal Society of Chemistry. This book was released on 2017-11-16 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry is one of the most widespread technologies in chemistry and has been increasingly used in biology with the rise of omics sciences. This book summarizes some important methodological approaches in mass spectrometry and applications in the field of chemical biology. The core chapters build on basic concepts introduced in the opening chapter and explore established fields such as high throughput screening, proteomics and metabolomics. Emerging applications of mass spectrometry in elucidating biosynthetic pathways, enzyme mechanisms and protein-protein interactions are then presented. Connections between these diverse research fields are highlighted throughout. The book concludes with a discussion of databases and future perspectives. This book will be a useful tool to early chemical biology researchers wishing to incorporate mass spectrometry as a tool in their research.

Download or read book Mass spectrometry of natural products written by and published by . This book was released on 1978 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Microbial Natural Products Chemistry written by Taícia Pacheco Fill and published by Springer Nature. This book was released on 2023-10-16 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​This book focuses on the importance of omics strategies and de-replication analysis to unveil new molecules from microbial sources with diverse chemical structures and biological functions. Chapters address metabolomics strategies, which will lead to a better understanding of the chemical interactions between microorganisms, plant-microorganisms, and virus-microorganisms. Authors also describe analytical tools used in microbial metabolomics and natural products discovery, in addition to describing a step-by-step protocol to identify and annotate metabolites using various databases and online platforms. The book presents the newest research, tools, and protocols for chemists, biochemists, bio-and chemical engineers, and biotechnologists, among others.

Download or read book Mass Spectrometry of Organic Ions written by F.W. McLafferty and published by Elsevier. This book was released on 2012-12-02 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry of Organic Ions covers the underlying theories and major applications of mass spectrometry. This 13-chapter book starts with a survey of the mechanisms by which organic ions can decompose and rearrange, as well as the generalized concept in terms of physical-organic chemistry. The discussion then shifts to the advantages and potential of mass spectrometry in structure determination by the elucidation of the empirical formulas of organic ions. Considerable chapters are devoted to the detailed correlations and mechanisms of the mass spectra of long-chain esters, alkylbenzenes, a variety of natural products, aliphatic compounds, and terpenes. The remaining chapters demonstrate the illustrative power of mass spectrometry in structure of petroleum, which is composed of hydrocarbon mixture. This book will be of great benefit to organic and analytical chemists, scientists, and students.

Download or read book Rays of Positive Electricity and Their Application to Chemical Analyses written by Joseph John Thomson and published by . This book was released on 1913 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Analytical Techniques for Natural Product Research written by Satyanshu Kumar and published by CABI. This book was released on 2015-12-15 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants are important source of lead molecules for drug discovery. These lead molecules serve as starting materials for laboratory synthesis of drug as well a model for production of biologically active compounds. Phytochemical processing of raw plant materials is essentially required to optimize the concentration of known constituents and also to maintain their activities. Extraction techniques and analytical techniques have played critical roles in phytochemical processing of raw materials. Extraction technologies from conventional extraction to green extraction as well as analytical techniques from single technique to hyphenated/coupled techniques most frequently used in phytochemistry laboratories are covered in the book.

Download or read book Organic Mass Spectrometry in Art and Archaeology written by Prof Maria Perla Colombini and published by John Wiley & Sons. This book was released on 2009-07-28 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers an overview of the analysis of art and archaeological materials using techniques based on mass spectrometry Illustrates basic principles, procedures and applications of mass spectrometric techniques. Fills a gap in the field of application on destructive methods in the analysis of museum objects Edited by a world-wide respected specialists with extensive experience of the GC/MS analysis of art objects Such a handbook has been long-awaited by scientists, restorers and other experts in the analysis of art objects