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Book Mutations that Disrupt Meiosis in Males of Drosophila Melanogaster

Download or read book Mutations that Disrupt Meiosis in Males of Drosophila Melanogaster written by John Marshall Ivy and published by . This book was released on 1981 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Homologous Chromosome Pairing in Drosophila Melanogaster Male Meiosis

Download or read book Homologous Chromosome Pairing in Drosophila Melanogaster Male Meiosis written by Amy Lynn Creekmore and published by . This book was released on 2001 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Chromosomes Today

    Book Details:
  • Author : Ettore Olmo
  • Publisher : Birkhäuser
  • Release : 2013-03-09
  • ISBN : 3034884842
  • Pages : 339 pages

Download or read book Chromosomes Today written by Ettore Olmo and published by Birkhäuser. This book was released on 2013-03-09 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromosomes Today, Volume 13 includes the plenary lectures presented at the 13th International Chromosome Conference, covering the most recent advances in the studies on chromosomes. The contributions in this volume were presented by some of the world's leaders in cytogenetic and molecular research and outline the present status of knowledge on the composition, structure, function and evolution of chromosomes, including, among others, the advancement of the human genome project. The use of cytogenetic studies has greatly increased in the last few years, resulting in a progressive improvement in the available methods that has consequently allowed a more detailed analysis of the molecular organization of eukaryotic chromosomes and a precise in situ localisation of specific gene sequences. This volume of Chromosomes Today provides up-to-date information regarding the topics at the forefront of chromosome research: genetic regulation, imprinting, DNA duplication, meiotic pairing, and the regulation of the...

Book Determining Requirements for Meiotic Pairing in Drosophila Melanogaster Spermatogenesis

Download or read book Determining Requirements for Meiotic Pairing in Drosophila Melanogaster Spermatogenesis written by Christopher Andrew Hylton and published by . This book was released on 2020 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Diploid germline cells must undergo two consecutive meiotic divisions before differentiating as haploid sex cells. During meiosis I, homologs pair and remain conjoined until segregation at anaphase. Drosophila melanogaster spermatocytes are unique in that the canonical events of meiosis I including synaptonemal complex (SC) formation, double-strand DNA breaks, and chiasmata are absent. Sex chromosomes pair at intergenic spacer sequences within the rDNA. Autosomes pair at numerous euchromatic homologies, but not at heterochromatin, suggesting that pairing may be limited to specific sequences. However, previous work generated from genetic segregation assays or observations of late prophase I/prometaphase I chromosome associations fail to differentiate pairing from maintenance of pairing (conjunction). To begin, the capability of X euchromatin to pair and conjoin with the Y chromosome was examined using an rDNA-deficient X and a series of Dp(1;Y) chromosomes. Genetic assays determined that duplicated X euchromatin can substitute for endogenous rDNA pairing sites; however, segregation was not proportional to homology length. Using fluorescent in situ hybridization (FISH) to early prophase I spermatocytes, pairing was shown to occur with high fidelity at all homologies tested. By comparing genetic and cytological data, we determined that centromere proximal pairings were best at segregation. Segregation was dependent on the conjunction protein Stromalin in Meiosis while the autosomal-specific Teflon was dispensable. Next, the ability of the X euchromatic homology to pair with and segregate from the heterolog chromosome 3 was examined using Dp(1;3) chromosomes containing X euchromatin duplications ranging in size from 21 to 177 Kb. In contrast to duplications of X euchromatin on the Y, duplications of X material on chromosome 3 are not as effective in directing segregation. In early prophase I, however, homologies on the X and chromosome 3 pair. Pairing between homologs is normally released at S2b of prophase I. Using a control probe to only select cells where chromosome 2 has already unpaired, the X and Dp(1;3) was unpaired in a significantly higher number of cells than was the X and Dp(1;Y). This result suggests different mechanisms exist to manage pairings between homologs and pairings between heterologs. The FISH pairing assay was used to score meiotic I nondisjunction (NDJ) and compared to genetic NDJ. Some NDJ frequencies were significantly different between the two methods. Data suggests genetic NDJ calculations are not always a true measure of the meiotic defect. The FISH pairing assay was also used to investigate an uncharacterized male meiotic mutant since the assay provides a rapid identification of the defective meiotic stage. FISH identified a unique defect that caused sister chromatids to segregate to opposite poles during meiosis I. This identification would not have been possible by only monitoring the outcome of meiosis through genetic crosses. The molecular techniques and approaches described within are suggested to be useful in defining the mechanisms regulating the establishment of conjunction and segregation between paired sequences."--Abstract from author supplied metadata. [This abstract has been edited to remove characters that will not display in this system. Please see the PDF for the full abstract.]

Book A Screen for Modifiers of Teflon Identifies Novel Components of the Meiotic Segregation Pathway in Male Drosophila Melanogaster

Download or read book A Screen for Modifiers of Teflon Identifies Novel Components of the Meiotic Segregation Pathway in Male Drosophila Melanogaster written by Amanda L. Thomas and published by . This book was released on 2007 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: The teflon (tef) gene is required specifically for ensuring adhesion between autosomes in male meiosis. In tef mutants, autosomal homologs pair correctly, but separate prior to metaphase, resulting in random segregation of homologs at meiosis I.

Book Fly Pushing

    Book Details:
  • Author : Ralph J. Greenspan
  • Publisher :
  • Release : 1997
  • ISBN :
  • Pages : 176 pages

Download or read book Fly Pushing written by Ralph J. Greenspan and published by . This book was released on 1997 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: The practicalities of "fly pushing"--an affectionate term for doing genetic experiments and crosses with Drosophila--is presented here for those who want to use fly genetics in their work, but have heretofore been unable to gain access to the "large folklore of classical genetic tools lurking somewhere in the fly field" (from the introduction). The practicalities of making crosses, isolating variants, mapping genes, constructing specific genotypes, and analyzing mutations are explained, with some theory thrown in to make the techniques intelligible. Requires only an elementary (undergraduate course level) knowledge of genetics. Spiral wire bound, with a cloth cover. Annotation copyrighted by Book News, Inc., Portland, OR

Book Entomology Abstracts

Download or read book Entomology Abstracts written by and published by . This book was released on 1998 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Mapping the Essential Genes in the Pericentromeric Heterochromatin of the Second Chromosome s Left Arm in Drosophila Melanogaster

Download or read book Mapping the Essential Genes in the Pericentromeric Heterochromatin of the Second Chromosome s Left Arm in Drosophila Melanogaster written by Richard Yuditskiy and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterochromatic regions perform essential roles in model organisms such as Drosophila melanogaster, yet not all have been genetically mapped. The current project focused on identifying and mapping the essential heterochromatic genes found in the lethal region of the left arm of the second chromosome (2Lh) in D. melanogaster, constructing a genetic map in the process. This was achieved by finding fatal mutations in D. melanogaster lines via the candidate gene approach, which compared genomic DNA sequences of potential mutant candidates with the genes control line sequence. To indicate their importance, the mutations found were discussed and their effects on the genes are explained. Six out of the seven essential genes have been located: one which was previously found (light), and five in this project: CG42748, Ir40a, CG17493, Slmap, and Cht10. The seventh and final gene, l(2)40Fe, has been deemed unfindable and is explained more thoroughly later in this paper.

Book Genetics Abstracts

Download or read book Genetics Abstracts written by and published by . This book was released on 2001 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Cumulated Index Medicus

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Advances in Genetics

    Book Details:
  • Author : Jeffrey C. Hall
  • Publisher : Elsevier
  • Release : 1994-05-27
  • ISBN : 9780120176311
  • Pages : 308 pages

Download or read book Advances in Genetics written by Jeffrey C. Hall and published by Elsevier. This book was released on 1994-05-27 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Under the leadership of Dr. Jeffrey C. Hall and Dr. Jay C. Dunlap, Advances in Genetics covers all genetic systems-from prokaryotic to human-with an eye toward identifying emerging problems as they coalesce. Volumes present both synoptic and topical reviews in a comprehensible, informative, and insightful manner. Articles range from detailed and discursive to brief and sharply focused, as benefits the problem under study. Founded in 1946 by Dr. Miloslav Demerc, this serial publication continues to be critical reading for researchers who need current overviews of areas outside their specialty and for students who need comprehensive introduction to topics genetic research. Under new editorial direction beginning with this volume Publishes comprehensive and timely chapters of genetic Delves into genetic phenomena at a molecular level Ties together related issues in cell and developmental biology and neurobiology

Book Chromosome Maps of Drosophila

Download or read book Chromosome Maps of Drosophila written by Veikko Sorsa and published by Springer. This book was released on 1988-07-31 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Heterochromatin

    Book Details:
  • Author : Ram Sagar Verma
  • Publisher : Cambridge University Press
  • Release : 1988-05-27
  • ISBN : 9780521334808
  • Pages : 324 pages

Download or read book Heterochromatin written by Ram Sagar Verma and published by Cambridge University Press. This book was released on 1988-05-27 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The material included in Heterochromatin is impressively comprehensive and provides timely, authoritative information that would otherwise be difficult to obtain.' BioScience