Download or read book Extracellular and Intracellular Signaling written by James D. Adams and published by Royal Society of Chemistry. This book was released on 2011 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.
Download or read book Adverse Events and Oncotargeted Kinase Inhibitors written by Giuseppe Tridente and published by Academic Press. This book was released on 2017-05-08 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse Events and Oncotargeted Kinase Inhibitors gathers and evaluates data on adverse events associated with tyrosine kinase inhibitors (TKIs), a powerful anti-tumor drug class that has recently been introduced for human therapy. This book compiles a comprehensive safety profile of each TKI from experiences in official therapeutic indications, also exploring off-label exploratory investigations and postmarketing pharmaceutical surveillance databases. A brief history of each drug's development and submission is provided, along with a more detailed analysis of the mechanism(s) of action involved in therapeutic activity or related to the insurgence of specific adverse events. Early chapters focus on general characteristics of TKIs, typology, and classification of adverse events, while the final chapters analyze TKIs as AE inducers and classes of AEs by system or organ involvement. This comprehensive resource compiles and critically reviews all of the relevant safety data for this class of drugs, with the goal of improving the understanding of pathogenesis and facilitating the prevention, monitoring, and management of these adverse events. - Offers a unique and comprehensive publication on the adverse events associated with a new and fast-growing class of medicines - Provides a systematic analysis of adverse events aimed at better prevention through understanding and offering insights for the development of safer drugs - Uses practical guidelines to establish a leading reference on this class of drugs for educators, researchers, drug developers, clinicians, safety professionals, and more
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1994 with total page 1470 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Highlights of Progress in Research on Cancer written by and published by . This book was released on 1957 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nutrition Action Healthletter written by and published by . This book was released on with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Epi Informatics written by Jose Medina-Franco and published by Academic Press. This book was released on 2016-02-24 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is intended for all those using or wanting to learn more about computational methodologies in epigenetic drug discovery, including molecular modelers, informaticians, pharmaceutical scientists, and medicinal chemists. With a better understanding of different molecular modeling and cheminformatic approaches, readers can incorporate these techniques into their own drug discovery projects that may involve chemical synthesis and medium- or high-throughput screening. In addition, this book highlights the significance of epigenetic targets to the public health for molecular modelers and chemoinformatians. The goal of this reference is to stimulate ongoing multidisciplinary research and to further improve current computational methodologies and workflows in order to accelerate the discovery and development of epi-drugs and epi-probes. - Focuses on the discovery of epi-drugs as candidates to be used in therapy including combined therapies - Describes new computational methodologies and screening assays utilizing recent and emerging novel structural data - Highlights the discovery, development and optimization of epi-probes, which are molecular probes that elucidate epigenetic mechanisms - Includes important topics such as computational-guided optimization of epi-hits, virtual screening to identify novel compounds for epigenetic targets, development and mining of epigenetic molecular databases, SAR modeling of screening data and much more
Download or read book Handbook of Secondary Fungal Metabolites written by Richard J. Cole and published by Gulf Professional Publishing. This book was released on 2003 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set is a desirable reference for a wide range of specialists who study secondary fungal metabolites ranging from pharmaceutical house researchers, agricultural researchers, those involved in food and feed control regulation, and veterinary researchers. It discusses in depth the molecular formula of, the molecular weights of, and fungal/plant source indexes of secondary fungal metabolites.
Download or read book Drug Transporters written by Guofeng You and published by John Wiley & Sons. This book was released on 2014-07-07 with total page 1012 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition overviews drug transporters and presents the principles of drug transport and associated techniques, featuring new chapters on multidrug and toxin extrusion proteins, placental transport, in silico approaches in drug discovery, and regulatory guidance for drug transport studies in drug development. • Describes drug transporter families, mechanisms, and clinical implications along with experimental methods for studying and characterizing drug transporters • Includes new chapters on multidrug and toxin extrusion proteins, placental transport and in silico approaches in drug discovery • Has a new chapter covering regulatory guidance for the evaluation of drug transport in drug development with global criteria used for drug transporters in clinical trials • Arranges material to go from fundamental mechanisms to clinical outcomes, making the book useful for novice and expert readers
Download or read book Placental Proteins written by A. Klopper and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In July 1978 a group met in Aberdeen to discuss the whole range of new proteins recently isolated from the human placenta. With the exception of Yuri Tatarinov all the main pioneers in the field were present, and this book arose from the discussions which took place. Each author was asked to bring a written man uscript corresponding to but not necessarily identical with their verbal presentation. Nobody was given a specified remit, for the reason that the subject is so new that it would be impossible to design the meeting or the book in advance. Each speaker was left free to put on display whatever he thought was interesting or important about the newly isolated proteins. Inevitably this has led to much overlap, since everybody tends to follow the same path at first. Nevertheless, we shall probably never achieve so much agreement again. Only Vernon Stevens was set a fixed title out side the immediate field of new placental proteins. This arose from the very exciting possibility that the new proteins could be used to induce an autoimmune state to products of conception and thus serve as the basis for a new method of contraception. There are few findings at present which bear specifically on this proposal, but the experience of Vernon Stevens with hCG could serve as a model of the problems that might be encountered with SP and PAPP-A.
Download or read book Gynecologic Radiation Therapy written by Akila N. Viswanathan and published by Springer Science & Business Media. This book was released on 2010-10-17 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in the treatment of gynecologic malignancies led to a new worldwide consensus to introduce image guidance to gynecologic radiation therapy, particularly to brachytherapy. The book summarizes the changed practice of management: treatment planning for cervical cancer, not modified for over 60 years, has been shifted to an image-based approach, endometrial cancer management with an increase in the use of chemotherapy and vaginal brachytherapy, and vaginal cancer therapy including image guidance and high-dose delivery with IMRT.
Download or read book Elsevier s Integrated Review Immunology and Microbiology E Book written by Jeffrey K. Actor and published by Elsevier Health Sciences. This book was released on 2011-09-28 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effectively merge basic science and clinical skills with Elsevier’s Integrated Review of Immunology and Microbiology, by Jeffrey K. Actor, PhD. This concise, high-yield title in the popular Integrated Review Series focuses on the core knowledge in immunology and microbiology while linking that information to related concepts from other basic science disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. . This concise and user-friendly reference provides crucial guidance for the early years of medical training and USMLE preparation. This title includes additional digital media when purchased in print format. For this digital book edition, media content is not included. Spend more time reviewing and less time searching thanks to an extremely focused, "high-yield" presentation. Gauge your mastery of the material and build confidence with case-based and USMLE-style questions that provide effective chapter review and quick practice for your exams. This title includes additional digital media when purchased in print format. For this digital book edition, media content is not included. Grasp and retain vital concepts more easily thanks to a color-coded format, succinct text, key concept boxes, and dynamic illustrations that facilitate learning in a highly visual approach. Effectively review for problem-based courses with the help of text boxes that help you clearly see the clinical relevance of the material.
Download or read book Death By Prescription written by Ray Strand and published by Thomas Nelson. This book was released on 2006-10-08 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experienced family doctor Ray Strand writes his patients prescriptions every week, but he also believes that prescribing drugs should be a last resort in most medical cases-not a first choice. In Death by Prescription he provides simple guidelines to help readers protect themselves and their families from suffering adverse reactions to prescription medication.
Download or read book Antifascisms written by David Ward and published by Fairleigh Dickinson Univ Press. This book was released on 1996 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an in-depth analysis of three of the most crucial years in twentieth-century Italian history, the years 1943-46. After more than two decades of a Fascist regime and a disastrous war experience during which Italy changed sides, these years saw the laying of the political and cultural foundations for what has since become known as Italy's First Republic. Drawing on texts from the literature, film, journalism, and political debate of the period, Antifascisms offers a thorough survey of the personalities and positions that informed the decisions taken in this crucial phase of modern Italian history.
Download or read book Physical Aspects of Medical Imaging written by B. M. Moores and published by John Wiley & Sons. This book was released on 1981 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vaccine Design written by Sunil Thomas and published by . This book was released on 2016 with total page 873 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Encyclopaedia of Food Science Food Technology and Nutrition written by R. Macrae and published by . This book was released on 1993 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromatin Proteins and Transcription Factors as Therapeutic Targets written by and published by Academic Press. This book was released on 2017-02-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatin Proteins and Transcription Factors as Therapeutic Targets, the latest volume in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.