Download or read book Management of the Patient at High Risk for Breast Cancer written by Nora M. Hansen and published by Springer Science & Business Media. This book was released on 2013-01-08 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of the Patient at High Risk for Breast Cancer provides a state-of-the art review of patients who are at high risk for breast cancer, how to identify them, the tools available for risk assessment and quantification and indications for genetic counseling and testing. The book summarizes the high risk breast imaging options, including newest techniques and schedules. Pathologic evaluation of high risk lesions are featured as well as the management issues surrounding these lesions. The volume also covers the management of concomitant cancer risk and screening strategies. A concise, yet comprehensive overview of the current status of the topic, Management of the Patient at High Risk for Breast Cancer serves as a useful resource for physicians and researchers dealing with and interested in patients at high risk for breast cancer.
Download or read book Breast Cancer Prevention and Treatment written by Lida A. Mina and published by Springer. This book was released on 2016-06-02 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniquely designed for oncologists and general practitioners, this book offers clinicians comprehensive guidelines when dealing with women at high risk for breast cancer. Written by experts in the field on the cutting edge of this research, the following questions will be answered for the reader by the end of the book: · Who is at elevated risk for breast cancer? · Who should be genetically screened? · When and how often should we obtain imaging? · What type of imaging is adequate? · What medications are available for prevention? · When is surgical intervention appropriate? · What lifestyle changes should be implemented to prevent this disaster? With one in eight women likely to contract breast cancer in her lifetime, the significance of identifying and managing the high-risk patient is evident. Breakthroughs in the identification of genes associated with breast carcinoma, particularly BRCA1 and 2, as well as other risk factors, influence not only how patients are screened, but also how they are treated. Breast Cancer Prevention and Treatment provides a guided approach to prevention of breast cancer in women at elevated risk for this malignancy.
Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Download or read book Reducing Breast Cancer Risk in Women written by B.A. Stoll and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer is not only a burning public issue, but very soon we shall see genetic testing for a woman's predisposition to breast cancer. Many women will be demanding to know their degree of risk and will need counselling to cope with that information. This book is particularly aimed at primary health care professionals, including physicians, medical assistants, nurses and counsellors, who daily deal with questions from women concerned about their risk of developing breast cancer. To answer such questions, this book has combined a guide to identifying women at higher risk to breast cancer, with a balanced review of approaches which aim to reduce that risk. The book provides practical general measures which may reduce risk for women at average risk. For women at clearly increased risk various protective options with different levels of efficacy and acceptability are discussed. Central to the book is the patient-centered view. We need to face reality that it still will take many years before the current clinical trials of preventive measures provide meaningful results. Meanwhile, women who seek to diminish their risk of breast cancer need all the available information. They must be given full responsibility to make an informed decision on their own health care. Reducing Breast Cancer Risk in Women is a practical handbook, technicalities have been deliberately kept to a minimum, making it concise and easy to read.
Download or read book High Risk Breast Cancer written by Joseph Ragaz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The many advances in breast cancer research, as well as the large quantity of published material, make it very difficult to gain insight into the global aspects of cancer management. To follow and understand all the new developments is becoming a major challenge. For this reason, the editors decided to bring together a group of top researchers in breast cancer to provide a comprehensive, yet readable conceptual review of the state of the art of breast cancer diagnosis and therapy. The proposal to focus the review on the quantitative assessment of the risk at diagnosis, the determination of which may permit selective therapies for individual patients, was met with enthusiastic approval, resulting in the present volume with contributions by the leading investigators in the field. While the volume relating to diagnosis, published re cently, focused on efforts leading to refinement at diagnosis of risk criteria sensitive enough to reliably distinguish the low- and high-risk categories, the second volume, by provid ing a review of the main problems and results of therapy given to high-risk patients, can be considered as a continua tion of the first book. A refined risk assessment at diagnosis and the application of the most suitable treatments to well selected individuals are the most important steps towards avoiding the present worrisome reality of overtreating the low risk and undertreating the high-risk patients. The first few chapters of the present volume offer an insight into the general management of early breast cancer.
Download or read book Breasts The Owner s Manual written by Kristi Funk and published by Thomas Nelson. This book was released on 2018-05-01 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: A national bestseller! Breast cancer surgeon Dr. Kristi Funk offers a comprehensive and encouraging approach to breast care and breast cancer. Empower yourself with facts and strategies to understand your breasts, reduce your cancer risk, and open your eyes to interventions and treatments. Most women don’t want to hear about breast cancer unless they have it and need to make some decisions, but these days news about breast cancer—the number one killer of women ages twenty to fifty-nine—is everywhere. Chances are you know someone who has had it. But did you know that choices you make every day bring you closer to breast cancer—or move you farther away? That there are ways to reduce your risk factors? And that many of the things you’ve heard regarding the causes of breast cancer are flat-out false? Based on Dr. Kristi Funk’s experience as a board-certified breast cancer surgeon, she knows for a fact that women have the power to reduce breast cancer risk in dramatic ways. Many women believe that family history and genetics determine who gets breast cancer, but that’s not true for most people. In fact, 87 percent of women diagnosed with breast cancer do not have a single first-degree relative with breast cancer. This book will help you: Learn the breast-health basics that every woman should know Reduce your cancer risk and recurrence risk based on food choices and healthy lifestyle changes backed by rigorous scientific research Understand the controllable and uncontrollable risk factors for breast cancer Outline your medical choices if you're at elevated risk for or are already navigating life with breast cancer There have been few solid guidelines on how to improve your breast health, lower your risk of getting cancer, and make informed medical choices after treatment—until now. With her book available in 10 languages and in more than 30 countries, Dr. Funk is passionate about her mission of educating as many women as possible about what they can do to stop breast cancer before it starts. Praise for Breasts: The Owner’s Manual: “Dr. Funk writes Breasts: The Owner’s Manual just like she talks: with conviction, passion, and a laser focus on you.”—Dr. Mehmet Oz, Host of The Dr. Oz Show “Breasts: The Owner’s Manual will become an indispensable and valued guide for women looking to optimize health and minimize breast illness.”—Debu Tripathy, MD, Professor and Chair, Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center “Breasts: The Owner’s Manual not only provides a clear path to breast health, but a road that leads straight to your healthiest self. As someone who has faced breast cancer, I suggest you follow it.”—Robin Roberts, Co-anchor, Good Morning America
Download or read book Women at High Risk to Breast Cancer written by B.A. Stoll and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reprint of the 1989 edition of this book has been made necessary by continuing demand after rapid exhaustion of the first printing. In the two years since its appearance, there has been relatively little expansion of knowledge on this topic, and its massive accumulation of references still remains an authoritative guide in the difficult task of developing a national breast cancer prevention model. At the same time, its thesis has been sharpened by the publication of a companion volume Approaches to Breast Cancer Prevention (Kluwer, 1991) similarly edited byrne. Breast cancer is on the increase throughout the Western world where it is a major source of anxiety among women. The disease is also becoming more frequent in Asian and South American countries where once it was relatively uncommon. Multiple fac tors are suspected of promoting the disease and the increasing risk is attributed to recent changes in life-style and diet. This book is intended to provide an authorita tive and balanced survey of the latest research into the genetic, familial, hormonal, reproductive, nutritional, social and geographic factors known to be associated with an increased predisposition to the disease.
Download or read book Management of Patients at High Risk for Breast Cancer written by Victor G. Vogel and published by Wiley-Blackwell. This book was released on 2000-10-03 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assessment and management of predisposition to specific diseases is currently a very hot dimension of medicine. Once purely the realm of epidemiologists, the emergence of molecular genetic testing and other highly sophisticated diagnostic and prognostic techniques has made risk assessment and care a part of the work of many clinicians--from GPs to the super-specialist. Nowhere has the study of "prognostic factors" been more high-profile (and more clinically fruitful) than in breast cancer. Breakthroughs in the identification of genes associated with breast carcinoma, particularly BRCA1 and 2, as well as other risk factors, influence not only how patients are screened, but also how they are treated. With one in nine women likely to contract breast cancer in her lifetime, the significance of identifying and managing the high-risk patient is evident.
Download or read book The Breast E Book written by Kirby I. Bland and published by Elsevier Health Sciences. This book was released on 2023-03-18 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multidisciplinary in scope and fully up to date with the latest advances in medical oncology and more, Bland and Copeland's The Breast, 6th Edition, covers every clinically relevant aspect of the field: cancer, congenital abnormalities, hormones, reconstruction, anatomy and physiology, benign breast disease, and more. In a practical, easy-to-use format ideal for today’s busy practitioners, this truly comprehensive resource is ideal for surgical oncologists, breast surgeons, general surgeons, medical oncologists, and others who need to stay informed of the latest innovations in this complex and fast-moving area. Offers the most comprehensive, up-to-date information on the diagnosis and management of, and rehabilitation following, treatment for benign and malignant diseases of the breast. Updates include an extensively updated oncoplastic section and extended medical and radiation oncology sections. Delivers step-by-step clinical guidance highlighted by hundreds of superb illustrations that depict relevant anatomy and pathology, as well as medical and surgical procedures. Reflects the collaborative nature of diagnosis and treatment among radiologists, pathologists, breast and plastic surgeons, radiation and medical oncologists, geneticists and other health care professionals who contribute to the management of patients with breast disease. Includes access to procedural videos that provide expert visual guidance on how to execute key steps and techniques.
Download or read book The Role of Obesity in Cancer Survival and Recurrence written by Institute of Medicine and published by National Academies Press. This book was released on 2012-06-12 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent research suggests that obesity and excess weight can play a prominent role in the incidence and progression of various cancers. Obesity results from an energy imbalance - that is, energy intake that is higher than energy expenditure - could also influence the growth of cancers. Recognizing the impact that current findings on obesity and cancer could have on future cancer prevention and care, the National Cancer policy Forum (NCPF) of the Institute of Medicine (IOM) help a 2-day workshop on "The Role of Obesity in Cancer Survival and Recurrence," in Washington, DC, on October 31 and November 1, 2011. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary reviews each presenter's latest clinical evidence on the obesity-cancer link and the molecular mechanisms that might explain that link. Clinicians, researchers, cancer survivors, and policy makers also discussed potential interventions to counter the effects of obesity on cancer, and research and policy measures needed to stem the rising tide of cancer mortality predicted by an increasingly overweight and older population worldwide. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary explores the complex web of molecular mechanisms that underlie the obesity-cancer link, the ways to design future studies to acquire the information needed to guide patient care, what to advise cancer patients about weight loss, diet, exercise, and other measures to reduce their risk of cancer progression or recurrence and policy suggestions related to research, education, and dissemination of the findings on obesity and cancer.
Download or read book Managing Breast Cancer Risk written by Monica Morrow and published by PMPH-USA. This book was released on 2003 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing Breast Cancer Risk is a single source for information needed by primary care physicians, nurses, gynecologists, as well as oncologic specialists who deal with women who are concerned about breast cancer. Its purpose is to bring together a multidisciplinary group of experts to address breast cancer risk in a clinically meaningful way. Chapters providing detailed information on individual risk factors are accompanied by a discussion of models, which integrate multiple factors for a more complete assessment of risk. Traditional strategies for risk management, including surveillance and prophylactic surgery, are reviewed, and the data on newer techniques such as ductal lavage and screening with magnetic resonance is presented. The rational for chemoprevention with selective estrogen receptor modulators (SERMS) is discussed, and the evidence for tamoxifen as a chemopreventative is updated. The potential for chemoprevention with newer SERMS and the aromatase inhibitors is reviewed. Finally, the critical (and often ignored) areas of quality of life and symptom management are addressed.
Download or read book Breast Cancer written by Kelly K. Hunt and published by Springer Science & Business Media. This book was released on 2001 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: BREAST CANCER is the first volume of The MD Anderson Cancer Care Series, featuring the best standard treatment protocols from the experts at MD Anderson Cancer Center. As more is learned about the relative roles of different treatment modalities, a pattern of practice is emerging where several different disciplines are involved early in the diagnostic and treatment phases of breast cancer. The impact of new and established diagnostic approaches that utilize radiodiagnosis and pathology in combination are requiring that a full range of special expertise from these disciplines be made available to patients. This clinical guidebook is an essential resource for the busy practitioner, allowing for quick, authoritative access to the latest and best in multimodality therapies. Topics covered in this volume include screening for early detection of breast cancer, hereditary breast/ovarian cancer genetic sydromes, diagnostic radiology, ultrasonography, pathology, surgical options, radiation therapy for early and advanced breast disease, tumor markers, standard and high-dose chemotherapy, hormonal therapy, reconstructive surgery, post-treatment rehabilitation, and symptom management and quality of life. Over 125 photographs and line-drawings illustrate the principles discussed in the text. This handbook will become an important guide and resource for community oncologists, as well as general surgeons, internists, and family practioners.
Download or read book Toxicities of Radiation Treatment for Breast Cancer written by Jean L. Wright and published by Springer. This book was released on 2019-03-15 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide to breast toxicity. Adjuvant radiation remains standard for a majority of women who undergo breast-conserving surgery for breast cancer, and indications for post-mastectomy and regional lymph node irradiation have also broadened with recent publications. At the same time, locoregional recurrence has declined and survival has improved in recent decades. In the current era of excellent breast cancer outcomes, then, considering the balance between toxicity and outcomes becomes paramount. Several recent editorials recommend considering toxicity against the potential benefit of adjuvant radiation in tailoring radiation decisions for individual patients. Thus, a clear understanding of the potential toxicities of adjuvant radiation for breast cancer is critical to optimizing outcomes in modern breast cancer management. Here, authors have collected recent data focused on toxicity of treatment that provide an opportunity for improving this optimization. Chapters cover both acute and late toxicity of radiation for breast cancer, including tailored risk assessment for each of these potential toxicities, considerations for including risk of toxicity in management decisions, and toxicity management strategies. This is an ideal guide for radiation oncologists, residents, and oncologists seeking to optimize care for their patients.
Download or read book Diet and Breast Cancer written by American Institute for Cancer Research and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth annual American Institute for Cancer Research (AICR) conference on diet, nutrition and cancer was held at the L'Enfant Plaza Hotel in Washington, D. C. , September 2~3, 1993. In keeping with present concerns and in line with current trends, the theme was "Diet and Breast Cancer. " This proceedings volume is comprised of chapters from the platform presentations of the two day conference and abstracts from the poster session held at the end of the first day. Experimentally, there is sufficient evidence to support a relationship between dietary fat and the risk of breast cancer. A meta-analysis was provided by data from 114 experiments with over 10,000 animals, divided into groups fed ad libitum on diets with different levels or sources of fat, or different levels of energy restriction. This exercise suggested that linoleic acid was a major determinant of mammary tumor development but that other fatty acids also enhanced mammary tumor development in animals. However, as mentioned by several speakers, results from epidemiological studies often are conflicting, thus leading to confusion among both health professionals and the public. Surveys of specific populations which have migrated from countries with low breast cancer rates to those with higher rates are often some of the most compelling studies with respect to a high fat diet-breast cancer association. Nonetheless, various cohort and prospective studies, some quite large, did not appear to show a relationship between consumption of fat (any type) and breast cancer.
Download or read book Early Diagnosis and Treatment of Cancer Series Breast Cancer E Book written by Lisa Jacobs and published by Elsevier Health Sciences. This book was released on 2010-07-15 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each volume in the Early Detection and Treatment of Cancer Series is packed with practical, authoritative information designed to cover the full range of diagnostic procedures, including pathologic, radiologic, bronchoscopic, and surgical aspects. You’ll be able to determine the safest, shortest, least invasive way to reach an accurate diagnosis; stage the disease; and choose the best initial treatment for early stages. Based on current evidence in the literature, authors provide clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed to diagnose and stage each type of cancer. Practical, authoritative, and highly-illustrated, this volume in the brand new Early Detection and Treatment of Cancer series covers current protocols and the latest advances in diagnostic imaging and molecular and serologic markers for breast cancer. Apply expert advice on the best “next-step plan for different presentations and tips for less invasive protocols. Get clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed for accurate diagnosis and staging. Clear figures, tables, and boxes illustrate step-by-step care of the full range of problems encountered. The small size and convenient format make this an ideal purchase for diagnostic reference. Outlines the steps after diagnosis to guide you through formulating a treatment or patient care plan. Emphasizes important points—such as the promising new breast cancer vaccine, sentinel node biopsy, and hormone receptor tests—with “key points boxes at the beginning of each chapter and pedagogic features throughout. Summarizes the process of accurately diagnosing and staging cancer in a logical, almost algorithmic, approach for easy reference. Discusses the treatment of early-stage disease so you have clear options for care. Complements the procedures outlined in the text with full-color photographs and line drawings to reinforce your understanding of the material.
Download or read book Digital Breast Tomosynthesis written by Alberto Tagliafico and published by Springer. This book was released on 2016-05-03 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive description of the screening and clinical applications of digital breast tomosynthesis (DBT) and offers straightforward, clear guidance on use of the technique. Informative clinical cases are presented to illustrate how to take advantage of DBT in clinical practice. The importance of DBT as a diagnostic tool for both screening and diagnosis is increasing rapidly. DBT improves upon mammography by depicting breast tissue on a video clip made of cross‐sectional images reconstructed in correspondence with their mammographic planes of acquisition. DBT results in markedly reduced summation of overlapping breast tissue and offers the potential to improve mammographic breast cancer surveillance and diagnosis. This book will be an excellent practical teaching guide for beginners and a useful reference for more experienced radiologists.
Download or read book Optimizing Risk Reduction Decisions for Women at High Risk of Breast Cancer written by Mehmet Ali Ergun and published by . This book was released on 2018 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer is the most common non-skin cancer and a leading cause of death for U.S. women population. Depending on the personal and hereditary factors, each woman has a different risk of developing a breast cancer and the focus of recent studies has been on identifying the high-risk patients and reducing the mortality and adverse effects due to a breast cancer. For high-risk women, we can prevent breast cancer mortality either by aggressive screening and early detection or by taking preventative treatments such as hormonal therapy (i.e. Tamoxifen, Raloxifene, Exemestane) or a risk reduction surgery (i.e. Bilateral Prophylactic Mastectomy). In Chapter 3, we focus on the problem faced by clinicians and patients who are at higher risk of breast cancer: should a high-risk patient choose to go for a preventative treatment given her current risk estimates, age and treatment history? We formulate this optimal decision-making problem for preventing breast cancer as a discrete time, finite-horizon Markov Decision Process (MDP) model. The objective of this model is to maximize the total expected quality-adjusted life years (QALYs) for a patient while assuming that the decision makers are risk neutral. We use data from literature and Surveillance Epidemiology and End Results (SEER) database for estimating the model parameters. The interventions we consider in the model are tamoxifen and mastectomy for pre-menopausal women and tamoxifen, raloxifene, exemestane and mastectomy for post-menopausal women. The optimal policy in the preliminary results shows that the patients who have 47% or more risk of breast cancer should have a mastectomy if they are between 35-40 years old and have no previous history of preventative treatment. The risk threshold goes up with age for the mastectomy decisions. Among the pharmacological interventions, tamoxifen is optimal for pre-menopausal women around the age of 40 with a lifetime risk of 39% or above which also corresponds to a 5-year risk of 1.6% and above around the age of 40. Exemestane is optimal for post-menopausal women with a lifetime risk of 13% (corresponding 5-year risk of 1%) or above after age of 51. Raloxifene is optimal only when we have elevated risks after age 65 or older. In Chapter 4, we consider optimal breast cancer risk reduction policies when direct and indirect costs associated with the treatments are considered. Although exemestane is the dominant recommendation in QALY maximizing model, the results of the cost model show that it is not cost-efficient up to willingness-to-pay (WTP) ratio of $150,000. We also demonstrated that the optimal policy is very sensitive to the discount factor from which most preventative interventions suffer. In Chapter 5, we investigate the effect of risk-averse behavior on the optimal policies for breast cancer risk reduction. We use two main approaches to model risk aversion. First, we use utility functions with different forms to see the effect of aversion from uncertainty. In the second approach, we utilize dynamic risk measures and explore cases in which aversion is from the cancer risk. While purely risk-averse utility functions lead to myopic decision making, increasing risk-aversion coefficient for dynamic risk measures result in more aggressive treatment policies.
